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Gene: Aco2 (aconitase 2, mitochondrial) Mus musculus
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Symbol: Aco2
Name: aconitase 2, mitochondrial
Description: Exhibits aconitate hydratase activity. Predicted to be involved in citrate metabolic process; isocitrate metabolic process; and tricarboxylic acid cycle. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in infantile cerebellar-retinal degeneration and optic atrophy. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human ACO2 (aconitase 2); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; mitochondrial complex II deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrabromodibenzodioxine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Aco-2; Aco3; aconitate hydratase, mitochondrial; citrate hydro-lyase; D10Wsu183e
Orthologs:
Homo sapiens (human) : ACO2 (aconitase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aco2 (aconitase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aco2 (aconitase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACO2 (aconitase 2)
Canis lupus familiaris (dog) : ACO2 (aconitase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aco2 (aconitase 2)
Sus scrofa (pig) : ACO2 (aconitase 2)
more info ...
Related Pseudogenes: Gm18398   Gm5421  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381581,872,463 - 81,915,137 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371581,702,893 - 81,745,567 (+)NCBIGRCm37mm9NCBIm37
MGSCv361581,699,718 - 81,742,392 (+)NCBImm8
Celera1583,991,539 - 84,036,379 (+)NCBICelera
Cytogenetic Map15 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Aco2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332293
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.