Rad50 (RAD50 double strand break repair protein) - Rat Genome Database

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Gene: Rad50 (RAD50 double strand break repair protein) Mus musculus
Analyze
Symbol: Rad50
Name: RAD50 double strand break repair protein
RGD ID: 733900
MGI Page MGI
Description: Predicted to enable DNA binding activity; identical protein binding activity; and protein-macromolecule adaptor activity. Predicted to contribute to 3'-5' exonuclease activity; DNA helicase activity; and single-stranded DNA endodeoxyribonuclease activity. Acts upstream of or within chromosome organization involved in meiotic cell cycle and regulation of mitotic cell cycle. Located in pronucleus. Is expressed in several structures, including aorta; hemolymphoid system gland; liver; lung; and testis. Human ortholog(s) of this gene implicated in transitional cell carcinoma. Orthologous to human RAD50 (RAD50 double strand break repair protein); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; non-homologous end joining pathway of double-strand break repair; INTERACTS WITH (S)-nicotine; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA repair protein RAD50; Mr; mRad50; Mrell; Rad; RAD50 homolog; Rad50l
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,540,346 - 53,598,146 (-)NCBIGRCm39mm39
GRCm39 Ensembl1153,540,346 - 53,598,146 (-)Ensembl
GRCm381153,649,519 - 53,707,319 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,649,519 - 53,707,319 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,463,021 - 53,520,821 (-)NCBIGRCm37mm9NCBIm37
MGSCv361153,492,993 - 53,550,720 (-)NCBImm8
Celera1158,229,063 - 58,286,859 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-methylcholine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
amphibole asbestos  (ISO)
arecoline  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
Brevetoxin B  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcium dichloride  (ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
clorgyline  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
disodium selenite  (ISO)
erlotinib hydrochloride  (ISO)
fenofibrate  (ISO)
fenvalerate  (ISO)
ferric oxide  (EXP)
flavone  (ISO)
folic acid  (EXP)
hydrogen peroxide  (ISO)
indole-3-methanol  (ISO)
isocyanates  (EXP)
kojic acid  (EXP)
L-ascorbic acid  (EXP)
lipopolysaccharide  (ISO)
lycopene  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (EXP)
myristicin  (ISO)
N,N-dimethylformamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel dichloride  (ISO)
nicotine  (EXP,ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenytoin  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
Ptaquiloside  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
retinyl acetate  (EXP)
rifampicin  (EXP)
rotenone  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
tamibarotene  (ISO)
testosterone enanthate  (ISO)
tetrachloroethene  (ISO)
thapsigargin  (EXP)
thioacetamide  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
usnic acid  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
wortmannin  (ISO)
zinc pyrithione  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal airway resistance  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal CD4-positive, alpha beta T cell morphology  (IAGP)
abnormal cell cycle checkpoint function  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal DNA methylation  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal gait  (IAGP)
abnormal gametogenesis  (IAGP)
abnormal hematopoietic stem cell morphology  (IAGP)
abnormal hematopoietic system morphology/development  (IAGP)
abnormal hematopoietic system physiology  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal immune system cell morphology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal intestine morphology  (IAGP)
abnormal pro-B cell morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal sperm number  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal T-helper 1 physiology  (IAGP)
abnormal T-helper 2 physiology  (IAGP)
abnormal testis morphology  (IAGP)
abnormal testis size  (IAGP)
abnormal thymus morphology  (IAGP)
absent bone marrow cell  (IAGP)
anemia  (IAGP)
chromosome breakage  (IAGP)
decreased airway responsiveness  (IAGP)
decreased apoptosis  (IAGP)
decreased B cell number  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased cell proliferation  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased embryo size  (IAGP)
decreased hepatocyte proliferation  (IAGP)
decreased IgE level  (IAGP)
decreased immature B cell number  (IAGP)
decreased inflammatory response  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-13 secretion  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased interleukin-5 secretion  (IAGP)
decreased litter size  (IAGP)
decreased macrophage cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased pro-B cell number  (IAGP)
decreased T cell number  (IAGP)
embryonic growth arrest  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
female infertility  (IAGP)
hydrocephaly  (IAGP)
impaired hematopoiesis  (IAGP)
increased cellular sensitivity to gamma-irradiation  (IAGP)
increased cellular sensitivity to ionizing radiation  (IAGP)
increased foot pad pigmentation  (IAGP)
increased hepatoblastoma incidence  (IAGP)
increased interleukin-13 secretion  (IAGP)
increased interleukin-4 secretion  (IAGP)
increased interleukin-5 secretion  (IAGP)
increased late pro-B cell number  (IAGP)
increased leukemia incidence  (IAGP)
increased liver adenoma incidence  (IAGP)
increased liver tumor incidence  (IAGP)
increased lymphoma incidence  (IAGP)
increased macrophage cell number  (IAGP)
increased skin pigmentation  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased tail pigmentation  (IAGP)
increased tumor latency  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
liver hypoplasia  (IAGP)
male infertility  (IAGP)
ovary atrophy  (IAGP)
pancytopenia  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
reduced female fertility  (IAGP)
small testis  (IAGP)
spleen hyperplasia  (IAGP)
testicular atrophy  (IAGP)
thrombocytopenia  (IAGP)
References

Additional References at PubMed
PMID:8910585   PMID:9149945   PMID:10349636   PMID:10377422   PMID:10464095   PMID:10655497   PMID:10704283   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12208847   PMID:12477932  
PMID:14610273   PMID:15378057   PMID:15489334   PMID:15507491   PMID:15589174   PMID:15608641   PMID:15615879   PMID:15734743   PMID:15880101   PMID:15965469   PMID:16141072   PMID:16141073  
PMID:16357220   PMID:17429352   PMID:17500065   PMID:17982445   PMID:18381424   PMID:18411308   PMID:19001091   PMID:19221393   PMID:19633670   PMID:19667071   PMID:19910469   PMID:20086180  
PMID:20483988   PMID:21267068   PMID:21677273   PMID:21677750   PMID:21725061   PMID:21873635   PMID:22027841   PMID:22771806   PMID:23248301   PMID:23569250   PMID:23643835   PMID:23665500  
PMID:23937658   PMID:24344331   PMID:24457600   PMID:24532689   PMID:24613343   PMID:24777530   PMID:25601756   PMID:26280532   PMID:26365490   PMID:26961797   PMID:27034005   PMID:27746211  
PMID:27878828   PMID:28132936   PMID:28671696   PMID:28819025   PMID:29091030   PMID:29459677   PMID:30017584  


Genomics

Comparative Map Data
Rad50
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,540,346 - 53,598,146 (-)NCBIGRCm39mm39
GRCm39 Ensembl1153,540,346 - 53,598,146 (-)Ensembl
GRCm381153,649,519 - 53,707,319 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,649,519 - 53,707,319 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,463,021 - 53,520,821 (-)NCBIGRCm37mm9NCBIm37
MGSCv361153,492,993 - 53,550,720 (-)NCBImm8
Celera1158,229,063 - 58,286,859 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.98NCBI
RAD50
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5132,556,019 - 132,646,349 (+)EnsemblGRCh38hg38GRCh38
GRCh385132,556,977 - 132,646,349 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,892,669 - 131,982,041 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,920,529 - 132,007,498 (+)NCBINCBI36hg18NCBI36
Build 345131,920,528 - 132,007,492NCBI
Celera5128,022,732 - 128,110,444 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,084,875 - 127,172,627 (+)NCBIHuRef
CHM1_15131,325,888 - 131,413,608 (+)NCBICHM1_1
Rad50
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21037,809,353 - 37,861,309 (-)NCBI
Rnor_6.0 Ensembl1039,001,498 - 39,054,142 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01039,002,130 - 39,054,042 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01038,783,860 - 38,835,810 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,112,733 - 39,164,694 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,121,979 - 39,173,935 (-)NCBI
Celera1037,153,558 - 37,205,520 (-)NCBICelera
Cytogenetic Map10q22NCBI
Rad50
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554083,953,801 - 4,035,494 (+)NCBIChiLan1.0ChiLan1.0
RAD50
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15134,134,506 - 134,222,261 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v05127,972,630 - 128,059,911 (+)NCBIMhudiblu_PPA_v0panPan3
RAD50
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,836,863 - 20,928,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,836,879 - 20,928,819 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,500,587 - 19,730,384 (+)NCBI
ROS_Cfam_1.01121,484,565 - 21,714,833 (+)NCBI
UMICH_Zoey_3.11120,203,382 - 20,433,320 (+)NCBI
UNSW_CanFamBas_1.01120,051,430 - 20,280,918 (+)NCBI
UU_Cfam_GSD_1.01120,693,292 - 20,923,363 (+)NCBI
Rad50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,536,406 - 115,761,319 (-)NCBI
SpeTri2.0NW_0049366472,546,100 - 2,637,524 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAD50
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12134,844,460 - 134,939,188 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,313,725 - 140,407,469 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAD50
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,375,206 - 35,458,801 (+)NCBI
Vero_WHO_p1.0NW_02366603442,481,288 - 42,568,716 (-)NCBI
Rad50
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,445,083 - 39,544,415 (-)NCBI

Position Markers
Rad50  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A5-B1UniSTS
cM Map1128.9UniSTS
stSG601375  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381153,692,124 - 53,692,840UniSTSGRCm38
MGSCv371153,505,626 - 53,506,342UniSTSGRCm37
Celera1158,271,663 - 58,272,380UniSTS
Cytogenetic Map11A5-B1UniSTS
Rad50  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A5-B1UniSTS
cM Map1128.9UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
14746971Manh70_mmandible shape 70 (mouse)112001506354015063Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2127257955272579Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
1300569Eae6b_msusceptibility to experimental allergic encephalomyelitis 6b (mouse)Not determined114005990154203622Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined114005990154203622Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
1300713Vmbic10_mventral midbrain iron content 10 (mouse)Not determined114288179954190238Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
4141770Tcpm1_mT-cell phenotype modifier 1 (mouse)Not determined5156165253725103Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:973
Count of miRNA genes:559
Interacting mature miRNAs:671
Transcripts:ENSMUST00000020649, ENSMUST00000124352, ENSMUST00000126121, ENSMUST00000128483, ENSMUST00000152598
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000020649   ⟹   ENSMUSP00000020649
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1153,649,519 - 53,707,319 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124352   ⟹   ENSMUSP00000119618
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1153,683,255 - 53,707,295 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126121
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1153,678,835 - 53,680,212 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128483   ⟹   ENSMUSP00000120869
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1153,674,755 - 53,707,319 (-)Ensembl
RefSeq Acc Id: ENSMUST00000152598
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1153,691,921 - 53,695,000 (-)Ensembl
RefSeq Acc Id: NM_009012   ⟹   NP_033038
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391153,540,346 - 53,598,146 (-)NCBI
GRCm381153,649,519 - 53,707,319 (-)ENTREZGENE
MGSCv371153,463,021 - 53,520,821 (-)RGD
Celera1158,229,063 - 58,286,859 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033038   ⟸   NM_009012
- UniProtKB: Q5SV02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000119618   ⟸   ENSMUST00000124352
RefSeq Acc Id: ENSMUSP00000020649   ⟸   ENSMUST00000020649
RefSeq Acc Id: ENSMUSP00000120869   ⟸   ENSMUST00000128483
Protein Domains
AAA_23   Zinc-hook

Promoters
RGD ID:6821693
Promoter ID:MM_KWN:7399
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000102756,   ENSMUST00000108933,   NM_009012,   OTTMUST00000012556,   OTTMUST00000071546,   UC007IWU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361153,520,326 - 53,520,977 (-)MPROMDB
RGD ID:8674622
Promoter ID:EPDNEW_M15342
Type:initiation region
Name:Rad50_1
Description:Mus musculus RAD50 double strand break repair protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381153,707,317 - 53,707,377EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109292 AgrOrtholog
Ensembl Genes ENSMUSG00000020380 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000020649 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000119618 UniProtKB/TrEMBL
  ENSMUSP00000120869 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020649 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000124352 UniProtKB/TrEMBL
  ENSMUST00000128483 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad50/SbcC_AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad50_eukaryotes UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zn_hook_RAD50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19360 UniProtKB/TrEMBL
MGD MGI:109292 ENTREZGENE
NCBI Gene 19360 ENTREZGENE
Pfam AAA_23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rad50_zn_hook UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rad50 PhenoGen
PROSITE ZN_HOOK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs rad50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8Y5I3_MOUSE UniProtKB/TrEMBL
  E9PUJ2_MOUSE UniProtKB/TrEMBL
  P70388 ENTREZGENE
  Q3UNL2_MOUSE UniProtKB/TrEMBL
  Q3V0R5_MOUSE UniProtKB/TrEMBL
  Q5SV02 ENTREZGENE, UniProtKB/TrEMBL
  Q99M38_MOUSE UniProtKB/TrEMBL
  RAD50_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q6PEB0 UniProtKB/Swiss-Prot
  Q8C2T7 UniProtKB/Swiss-Prot
  Q9CU59 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 Rad50  RAD50 double strand break repair protein    RAD50 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED