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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Chemical and Drug Induced Liver Injury
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Accession:DOID:9007383 term browser browse the term
Definition:A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
Synonyms:exact_synonym: Chemically Induced Liver Toxicity;   Drug Induced Acute Liver Injury;   Drug Induced Liver Disease;   Drug Induced Liver Injury;   Drug-Induced Liver Diseases;   Drug-Induced Liver Injuries;   Toxic Hepatitis;   chemically-induced liver toxicities;   hepatotoxicity;   toxic hepatitides
 narrow_synonym: Drug-induced liver injury due to flucloxacillin
 primary_id: MESH:D056486
 alt_id: RDO:0007742
 xref: EFO:0004228;   EFO:0011052;   NCI:C84427


show annotations for term's descendants           Sort by:
Chemical and Drug Induced Liver Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 severity ISO DNA:SNP: :rs2287616(human) RGD PMID:27293027 RGD:14402413 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A severity
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP::2677G>T/A(rs2032582)(human)		 CTD
RGD		 PMID:20623750 PMID:26134275 PMID:26134275 PMID:27296832 RGD:11041130, RGD:14700895 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:27193730 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18466103 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter:-24C>T(human)		 CTD
RGD		 PMID:18381794 PMID:18466103 PMID:25196354 PMID:17241877 RGD:14700812, RGD:14700814 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abi1 abl-interactor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr17:85,098,837...85,179,829
Ensembl chr17:85,098,550...85,179,792 		JBrowse link
G Ace angiotensin I converting enzyme IEP mRNA:increased expression:liver (rat) RGD PMID:25143335 RGD:25671447 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr14:75,133,986...75,176,767
Ensembl chr14:75,094,676...75,176,205 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541 		JBrowse link
G Actb actin, beta IEP
ISO		 mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25231249 PMID:22563491 RGD:9587759 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actn4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Actr3 actin related protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Ada adenosine deaminase IEP protein:increased expression:liver RGD PMID:21161045 RGD:5128859 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24646716 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:20709802 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adipor2 adiponectin receptor 2 severity IEP associated with obesity, LPS;mRNA:decreased expression:liver (rat) RGD PMID:23838384 RGD:8695926 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Adora2b adenosine A2B receptor ISO CTD Direct Evidence: therapeutic CTD PMID:35292334 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:29499335 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor ISO
IEP		 CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:decreased expression:liver (rat)		 CTD
RGD		 PMID:21890736 PMID:34848246 PMID:28959666 RGD:401794432 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25743375 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ak4 adenylate kinase 4 IEP protein:increased expression:liver (rat) RGD PMID:16538043 RGD:2301096 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:32805337 PMID:29763686 RGD:27226688 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Alb albumin treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18779383 PMID:22310181 PMID:27567545 RGD:14694844 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility
severity		 IEP
ISO		 protein:increased expression:liver
DNA:deletion:exon 3 (mouse)		 RGD PMID:21138988 PMID:24492981 PMID:30121625 RGD:7241599, RGD:14975148, RGD:15036810 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16115720 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18779383 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Anxa2 annexin A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa6 annexin A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Apoa1 apolipoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoe apolipoprotein E ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apoh apolipoprotein H IEP
ISO		 mRNA:increased expression:plasma:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16099942 PMID:23288050 RGD:10054107 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Arg1 arginase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22872058 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20935161 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Atg5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22491424 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:97,656,725...97,672,295
Ensembl chr 6:97,656,576...97,672,303 		JBrowse link
G Avp arginine vasopressin ISO DNA:SNP:intron: (rs2282018) RGD PMID:28462386 RGD:408364979 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:25447754 RGD:10053709 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:17906064 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Bdkrb2 bradykinin receptor B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30685357 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Blvrb biliverdin reductase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 ISO CTD Direct Evidence: therapeutic CTD PMID:36602574 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503 		JBrowse link
G Brd4 bromodomain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Btd biotinidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15469856 NCBI chr16:6,863,068...6,894,345
Ensembl chr16:6,862,407...6,940,945 		JBrowse link
G C3 complement C3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cabp1 calcium binding protein 1 IEP protein:increased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927 		JBrowse link
G Cadps2 calcium dependent secretion activator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829 		JBrowse link
G Canx calnexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769 		JBrowse link
G Car3 carbonic anhydrase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 PMID:25231249 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:25447754 RGD:10053709 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cast calpastatin IEP RGD PMID:16871587 RGD:5683869 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver		 CTD
RGD		 PMID:20623750 PMID:25231249 PMID:21138988 RGD:7241599 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20623750 PMID:30663942 PMID:21813474 RGD:14995458, RGD:14995466 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 susceptibility ISO acetaminophen RGD PMID:24770590 RGD:14401733 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cdc25b cell division cycle 25B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681 		JBrowse link
G Cela1 chymotrypsin like elastase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285 		JBrowse link
G Cfap20 cilia and flagella associated protein 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr19:9,608,867...9,622,558
Ensembl chr19:9,608,859...9,622,558 		JBrowse link
G Cfh complement factor H ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20197374 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Ckb creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Clu clusterin ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:16679477 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Comt catechol-O-methyltransferase IEP protein:decreased expression:liver RGD PMID:21138988 RGD:7241599 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Coq9 coenzyme Q9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949 		JBrowse link
G Cp ceruloplasmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpb2 carboxypeptidase B2 IEP mRNA,protein:increased expression,increased activity:liver,plasma RGD PMID:19386599 RGD:7243112 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A IEP mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:20005281 PMID:33882750 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ctnnb1 catenin beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19679878 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctse cathepsin E ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16118408 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 ISO CTD Direct Evidence: therapeutic CTD PMID:11739529 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:38614205 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16118408 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 ISO mRNA, protein:decreased expression:kidney (mouse) RGD PMID:26476181 RGD:25671412 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 PMID:33814510 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12963435 PMID:28762043 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO DNA:hypermethylation:promoter RGD PMID:27490558 RGD:14700879 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
associated with Endotoxemia
DNA:hypermethylation:promoter		 CTD
RGD		 PMID:12668988 PMID:16770646 PMID:21741958 PMID:28762043 PMID:25681370 More... RGD:14700872, RGD:14700873, RGD:14700878, RGD:14700879, RGD:14700901 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28762043 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25448281 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609 		JBrowse link
G Ddb1 damage-specific DNA binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:207,252,890...207,278,685
Ensembl chr 1:207,252,890...207,278,676 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dhfr dihydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648163 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521 		JBrowse link
G Dsc2 desmocollin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392 		JBrowse link
G E2f1 E2F transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25411909 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946 		JBrowse link
G Endog endonuclease G IEP protein:decreased expression:mitochondrion: RGD PMID:22509279 RGD:9685364 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932 		JBrowse link
G Eng endoglin IEP protein:increased expression:liver (rat) RGD PMID:21146604 RGD:7257529 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Eno1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:25231249 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 IEP protein:increased activity:serum: RGD PMID:17850827 RGD:9685426 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Erlec1 endoplasmic reticulum lectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr14:104,655,745...104,693,508
Ensembl chr14:104,655,673...104,693,480 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30538632 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:22019897 RGD:11041813 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472 		JBrowse link
G F3 coagulation factor III, tissue factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22407844 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:26062544 PMID:25447754 RGD:11341803, RGD:10053709 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fads1 fatty acid desaturase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fads2 fatty acid desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fas Fas cell surface death receptor IEP protein:increased expression:liver (rat) RGD PMID:16831245 RGD:8662853 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fasn fatty acid synthase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fcmr Fc mu receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Fga fibrinogen alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:20974703 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgf21 fibroblast growth factor 21 severity IEP mRNA:increased expression:liver (rat) RGD PMID:29883717 RGD:15045603 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21135413 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:24973094 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Ftl1 ferritin light chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 ISO mRNA:decreased expression:liver (mouse) RGD PMID:28189721 RGD:14695531 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase treatment IEP RGD PMID:21864513 RGD:10449168 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Ganab glucosidase II alpha subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695 		JBrowse link
G Gc GC, vitamin D binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19481141 PMID:17573345 RGD:10402383 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gda guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdi1 GDP dissociation inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:152,087,611...152,094,274
Ensembl chr  X:152,087,444...152,094,272 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment ISO
IDA		 RGD PMID:22033404 PMID:15968720 RGD:9685722, RGD:9685727 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869 		JBrowse link
G Ggh gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:21219404 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP RGD PMID:10934156 RGD:14701049 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:34151639 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Glud1 glutamate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:33483742 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529 		JBrowse link
G Gpt glutamic--pyruvic transaminase treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression, activity:serum:		 CTD
RGD		 PMID:145039 PMID:19481104 PMID:28487901 PMID:21772750 PMID:27293452 More... RGD:14975162, RGD:14975166, RGD:14975168, RGD:14975249, RGD:14975249 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 IEP
ISO		 protein:increased expression, activity:serum: RGD PMID:19085960 PMID:19085960 RGD:14975249, RGD:14975249 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Grk4 G protein-coupled receptor kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr14:75,998,554...76,080,808
Ensembl chr14:76,006,218...76,080,693 		JBrowse link
G Gsn gelsolin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP
ISO		 mRNA, protein:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25226513 PMID:28069987 PMID:23554813 PMID:24154663 RGD:7257532, RGD:10401878 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28412881 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 no_association ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:liver		 CTD
RGD		 PMID:17465707 PMID:18666253 PMID:21138988 PMID:29523098 PMID:24903797 More... RGD:7241599, RGD:14700937, RGD:14700941, RGD:14700959, RGD:14700970 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 ISO CTD Direct Evidence: therapeutic CTD PMID:25743375 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:25226513 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18397238 PMID:18666253 PMID:25226513 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:23265463 RGD:8693741 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hacl1 2-hydroxyacyl-CoA lyase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA:increased expression:hepatocyte RGD PMID:24373749 RGD:11041724 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hao2 hydroxyacid oxidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19783637 PMID:29091898 RGD:15090820 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:18227147 PMID:22688006 PMID:22886620 PMID:29091898 RGD:10762620, RGD:15090820 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 PMID:22872058 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hpx hemopexin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Hrh2 histamine receptor H 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22926047 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP protein:altered localization:liver (rat) RGD PMID:12376827 RGD:10059389 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:29091898 RGD:15090820 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:31121248 RGD:14985250 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ido2 indoleamine 2,3-dioxygenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:32289347 NCBI chr16:67,459,158...67,498,052
Ensembl chr16:67,459,190...67,496,324 		JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12153990 PMID:21245496 PMID:30013034 RGD:14975100 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23639586 PMID:25226513 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il11 interleukin 11 ISO CTD Direct Evidence: therapeutic CTD PMID:11421492 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: therapeutic CTD PMID:36520315 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19633216 PMID:24949944 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19164858 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: therapeutic CTD PMID:8218930 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta treatment IDA
ISO
IEP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:19164858 PMID:28138970 PMID:23102243 PMID:29278859 PMID:31077717 More... RGD:7204421, RGD:13793380, RGD:14975281, RGD:15036799, RGD:15090820 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il22 interleukin 22 ISO CTD Direct Evidence: therapeutic CTD PMID:15122762 PMID:16212920 PMID:23375450 NCBI chr 7:53,801,206...53,805,673
Ensembl chr 7:53,801,206...53,806,186 		JBrowse link
G Il4 interleukin 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21094227 PMID:21735453 PMID:22107450 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 treatment ISO
IEP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:7532385 PMID:15763341 PMID:29091898 RGD:15090820 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Immt inner membrane mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:103,880,482...103,919,116
Ensembl chr 4:103,880,459...103,919,109 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:30515189 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO RGD PMID:18417483 RGD:6893370 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kitlg KIT ligand ISO CTD Direct Evidence: therapeutic CTD PMID:12594235 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:30685357 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Krt18 keratin 18 ISO mRNA, protein:increased expression:liver (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19783637 PMID:33483742 PMID:38521541 PMID:17340120 RGD:18337498 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt8 keratin 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Lap3 leucine aminopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Lcat lecithin cholesterol acyltransferase IEP mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lcn2 lipocalin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20362651 PMID:20623750 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldlr low density lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:36108984 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lgals3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22461450 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lipc lipase C, hepatic type IEP mRNA:decreased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lpl lipoprotein lipase treatment IEP RGD PMID:27071702 RGD:13794380 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrat lecithin retinol acyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Ltb4r leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:28487374 NCBI chr15:29,263,199...29,265,716 JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16141546 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18700144 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mat1a methionine adenosyltransferase 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mccc1 methylcrotonyl-CoA carboxylase subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:118,799,147...118,851,181
Ensembl chr 2:118,799,150...118,851,222 		JBrowse link
G Mdh1 malate dehydrogenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Me1 malic enzyme 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Med1 mediator complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16109766 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Mir100 microRNA 100 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304 		JBrowse link
G Mir103a1 microRNA 103a-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr10:20,244,412...20,244,497
Ensembl chr10:20,244,412...20,244,497 		JBrowse link
G Mir106b microRNA 106b IEP
IDA		 miRNA:decreased expression:liver (rat)
DNA:hypermethylation:promoter		 RGD PMID:29554950 PMID:29554950 RGD:15042854, RGD:15042854 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425 		JBrowse link
G Mir107 microRNA 107 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853 		JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir10b microRNA 10b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546 		JBrowse link
G Mir122 microRNA 122 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22045675 PMID:22363424 PMID:25359176 PMID:25527335 PMID:26489516 More... NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir1249 microRNA 1249 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712 		JBrowse link
G Mir125b1 microRNA 125b-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir1306 microRNA 1306 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:82,709,651...82,709,723
Ensembl chr11:82,709,637...82,709,719 		JBrowse link
G Mir130a microRNA 130a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir130b microRNA 130b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:83,880,163...83,880,244
Ensembl chr11:83,880,163...83,880,244 		JBrowse link
G Mir132 microRNA 132 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir141 microRNA 141 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 PMID:28545106 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332 		JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir143 microRNA 143 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30125006 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir148a microRNA 148a ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858 		JBrowse link
G Mir150 microRNA 150 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Mir151b microRNA 151b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 7:105,172,377...105,172,496
Ensembl chr 7:105,172,377...105,172,496 		JBrowse link
G Mir152 microRNA 152 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir155 microRNA 155 treatment ISO RGD PMID:29420849 PMID:27673475 PMID:26867493 RGD:21409750, RGD:25671463, RGD:25671474 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir17 microRNA 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir188 microRNA 188 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794 		JBrowse link
G Mir18a microRNA 18a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir191 microRNA 191 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:109,264,098...109,264,188 JBrowse link
G Mir192 microRNA 192 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22045675 PMID:25359176 PMID:28483554 PMID:28545106 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
G Mir193a microRNA 193a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir193b microRNA 193b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824 		JBrowse link
G Mir194-1 microRNA 194-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28844483 NCBI chr13:96,851,166...96,851,248
Ensembl chr13:96,851,166...96,851,248 		JBrowse link
G Mir19a microRNA 19a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir1b microRNA 1b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30125006 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Mir200c microRNA 200c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir21 microRNA 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir210 microRNA 210 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir217 microRNA 217 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609 		JBrowse link
G Mir22 microRNA 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir221 microRNA 221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:serum,liver RGD PMID:28646120 RGD:21408574 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir23a microRNA 23a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mir23b microRNA 23b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763 		JBrowse link
G Mir27b microRNA 27b ISO CTD Direct Evidence: marker/mechanism CTD PMID:25359176 PMID:28545106 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir29b2 microRNA 29b-2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Mir301a microRNA 301a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435 		JBrowse link
G Mir30a microRNA 30a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 PMID:25359176 PMID:28545106 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir30b microRNA 30b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325 		JBrowse link
G Mir320a microRNA 320a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 PMID:30125006 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473 		JBrowse link
G Mir328 microRNA 328 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849 		JBrowse link
G Mir337 microRNA 337 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998 		JBrowse link
G Mir342 microRNA 342 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir345 microRNA 345 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir34a microRNA 34a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mir3545 microRNA 3545 ISO CTD Direct Evidence: therapeutic CTD PMID:32659284 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656 		JBrowse link
G Mir361 microRNA 361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275 		JBrowse link
G Mir410 microRNA 410 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434 		JBrowse link
G Mir423 microRNA 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mir455 microRNA 455 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 5:76,689,313...76,689,390
Ensembl chr 5:76,689,313...76,689,390 		JBrowse link
G Mir484 microRNA 484 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760 		JBrowse link
G Mir497 microRNA 497 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir499a microRNA 499a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 3:144,110,469...144,110,533
Ensembl chr 3:144,110,469...144,110,533 		JBrowse link
G Mir503 microRNA 503 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393 		JBrowse link
G Mir592 microRNA 592 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 PMID:28545106 NCBI chr 4:56,505,280...56,505,375
Ensembl chr 4:56,505,280...56,505,375 		JBrowse link
G Mir764 microRNA 764 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22363424 NCBI chr  X:110,678,597...110,678,704
Ensembl chr  X:110,678,597...110,678,704 		JBrowse link
G Mir877 microRNA 877 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27713024 NCBI chr20:2,811,476...2,811,560
Ensembl chr20:2,811,476...2,811,560 		JBrowse link
G Mir93 microRNA 93 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir99a microRNA 99a ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Mirlet7b microRNA let-7b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 PMID:30125006 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265 		JBrowse link
G Mirlet7d microRNA let-7d ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990 		JBrowse link
G Mirlet7g microRNA let-7g ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388 		JBrowse link
G Mirlet7i microRNA let-7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15763341 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416 		JBrowse link
G Mst1r macrophage stimulating 1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22575169 NCBI chr 8:108,596,100...108,611,441
Ensembl chr 8:108,597,299...108,612,455 		JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 IEP mRNA:decreased expression:blood RGD PMID:20130021 RGD:8657129 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase treatment ISO CTD Direct Evidence: marker/mechanism
associated with precursor lymphoblastic lymphoma/leukemia; DNA:SNP: :677C>T(human)		 CTD
RGD		 PMID:18551038 PMID:19648163 PMID:30545275 RGD:14696733 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtpn myotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Mug2 murinoglobulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ameliorates ISO RGD PMID:17615358 RGD:150521532 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nat2 N-acetyltransferase 2 treatment ISO associated with Tuberculosis;DNA:haplotype: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11915035 PMID:16799928 PMID:17950035 PMID:25693865 PMID:18023090 RGD:8552665 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 ISO CTD Direct Evidence: therapeutic CTD PMID:34192554 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment ISO
IEP		 CTD Direct Evidence: therapeutic
induced by methotrexate (CHEBI:44185), treated by ferulic acid (CHEBI:17620)		 CTD
RGD		 PMID:22491424 PMID:22627062 PMID:24813929 PMID:26958860 PMID:30215777 More... RGD:6893370, RGD:15090820, RGD:21201280, RGD:21201283, RGD:21201305, RGD:21201308 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 treatment
susceptibility		 IEP
ISO		 associated with tuberculosis ;DNA:SNPs,haplotypes: 3'utr,5'utr: (rs78872571,rs4647992) (human) RGD PMID:29091898 PMID:31490979 RGD:15090820, RGD:40902984 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr14:35,626,086...35,667,505
Ensembl chr14:35,626,066...35,667,498 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Notch1 notch receptor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:30394310 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nox4 NADPH oxidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IDA
ISO
IEP		 RGD PMID:28522909 PMID:28472605 PMID:29091898 RGD:13439737, RGD:13439739, RGD:15090820 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29943110 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 treatment ISO RGD PMID:24497272 RGD:10448995 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 ISO CTD Direct Evidence: therapeutic CTD PMID:17256725 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 treatment
severity		 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:liver (rat)
mRNA:decreased expression:liver (rat)		 CTD
RGD		 PMID:12875239 PMID:20573685 PMID:22711662 PMID:30068870 PMID:28827769 More... RGD:14701035, RGD:14701036, RGD:15042870, RGD:15045609, RGD:15090820 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism|therapeutic
associated with tuberculosis ;DNA:SNP,haplotypes:promoter: (rs3814055) (human)		 CTD
RGD		 PMID:19797606 PMID:28058446 PMID:31490979 RGD:40902984 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14742670 PMID:25656644 PMID:28058446 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29515023 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Nrep neuronal regeneration related protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Ntn1 netrin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:35292334 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO CTD Direct Evidence: therapeutic CTD PMID:33812996 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561 		JBrowse link
G Obp3 alpha-2u globulin PGCL4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757 		JBrowse link
G Ociad1 OCIA domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr14:34,897,851...34,915,291
Ensembl chr14:34,897,847...34,915,286 		JBrowse link
G Ogdh oxoglutarate dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Olr59 olfactory receptor 59 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Pah phenylalanine hydroxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130 		JBrowse link
G Pan2 poly(A) specific ribonuclease subunit PAN2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 7:729,146...747,744
Ensembl chr 7:729,562...747,744 		JBrowse link
G Panx1 Pannexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29246445 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Park7 Parkinsonism associated deglycase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pcolce procollagen C-endopeptidase enhancer ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr12:19,084,191...19,090,508
Ensembl chr12:19,084,210...19,090,508 		JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:21182459 PMID:31809757 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172 		JBrowse link
G Pgm1 phosphoglucomutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plg plasminogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22507835 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Pls3 plastin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Pnp purine nucleoside phosphorylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit no_association
susceptibility		 ISO
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:missense mutations:cds:p.Q1236H, p.E1143G (33708G>T, 3428A>G) (human)
DNA:missense mutation:cds:p.W748S, p.E1143G (2243G>C, 3428A>G) (human)		 CTD
RGD		 PMID:18208989 PMID:20138553 PMID:30255931 PMID:25065347 RGD:15039297, RGD:15039302 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Polr2g RNA polymerase II subunit G ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 1:205,689,160...205,692,537
Ensembl chr 1:205,689,160...205,692,686 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO LPS-induced acute liver damage
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:24385052 PMID:38181850 PMID:21262334 RGD:5509941 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO mRNA, protein:decreased expression:liver RGD PMID:26599535 RGD:11554658 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Pptc7 protein phosphatase targeting COQ7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr12:34,249,963...34,288,339
Ensembl chr12:34,249,977...34,288,339 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 treatment IEP RGD PMID:29091898 RGD:15090820 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkcd protein kinase C, delta ISO CTD Direct Evidence: therapeutic CTD PMID:30393195 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:21224054 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Ptf1a pancreas associated transcription factor 1a ISO CTD Direct Evidence: therapeutic CTD PMID:21182459 NCBI chr17:82,051,281...82,053,135
Ensembl chr17:82,051,281...82,053,135 		JBrowse link
G Ptges2 prostaglandin E synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31444509 NCBI chr 3:15,690,501...15,697,688
Ensembl chr 3:15,690,501...15,697,688 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment ISO
IEP		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:11743745 PMID:29091898 RGD:15090820 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pum1 pumilio RNA-binding family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039 		JBrowse link
G Pygl glycogen phosphorylase L ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:serum (rat)		 CTD
RGD		 PMID:25231249 PMID:25336395 RGD:21079733 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310 		JBrowse link
G Rasa1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rbp1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rdh13 retinol dehydrogenase 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27865848 NCBI chr 1:69,373,014...69,401,454
Ensembl chr 1:69,373,113...69,400,908 		JBrowse link
G Reep5 receptor accessory protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509 		JBrowse link
G Rgn regucalcin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 ISO CTD Direct Evidence: therapeutic
protein:increased expression:liver (mouse)		 CTD
RGD		 PMID:26769846 PMID:28205631 RGD:127229945 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G RT1-Ba RT1 class II, locus Ba susceptibility ISO DNA:polymorphism: :HLA-DQA1*0102(human)
associated with tuberculosis;DNA:polymorphism: :HLA-DQA1*0102(human)		 RGD PMID:20639878 PMID:12359646 RGD:14398844, RGD:14401573 NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Bb RT1 class II, locus Bb susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism, haplotype
DNA:polymorphism: :HLA-DQB1*05(human)		 CTD
RGD		 PMID:21570397 PMID:26959717 PMID:25250564 RGD:11573514, RGD:36174016 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-CE16 RT1 class I, locus CE16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21570397 PMID:28043905 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21570397 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G S100a11 S100 calcium binding protein A11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 IEP mRNA:increased expression:liver (rat) RGD PMID:28959666 RGD:401794432 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Selenbp1 selenium binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594 		JBrowse link
G Sema3a semaphorin 3A ISO CTD Direct Evidence: therapeutic CTD PMID:33290778 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Sema4a semaphorin 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:33290778 NCBI chr 2:173,896,432...173,917,903
Ensembl chr 2:173,896,439...173,914,442 		JBrowse link
G Senp2 SUMO specific peptidase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:29535048 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238 		JBrowse link
G Serpina1 serpin family A member 1 susceptibility IEP
ISO		 protein:decreased expression:plasma
DNA:missense mutation:cds:p.E264V(human)		 RGD PMID:11140575 PMID:20170533 RGD:1643168, RGD:14695048 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serpina6 serpin family A member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO associated with precursor lymphoblastic lymphoma/leukemia;DNA:SNPs: :DNA:SNPs: :677C>T, 1298A>C(human) RGD PMID:23183238 RGD:14696750 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serping1 serpin family G member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sesn2 sestrin 2 ISO CTD Direct Evidence: therapeutic CTD PMID:28209544 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sgf29 SAGA complex associated factor 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:181,238,458...181,271,931
Ensembl chr 1:181,238,468...181,274,781 		JBrowse link
G Shc1 SHC adaptor protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 PMID:32659284 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 IEP mRNA:decreased expression:liver (rat) RGD PMID:28827769 RGD:15045609 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc10a7 solute carrier family 10, member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464 		JBrowse link
G Slc13a4 solute carrier family 13 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc25a29 solute carrier family 25 member 29 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 treatment IEP RGD PMID:9200186 RGD:151357001 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Snx18 sorting nexin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr 2:45,232,325...45,258,345
Ensembl chr 2:45,232,325...45,258,345 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 PMID:27349771 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 susceptibility
severity
treatment		 ISO
IMP		 CTD Direct Evidence: marker/mechanism
DNA:SNP:cds:p.Val16Ala(human)
associated with acute lymphoblastic leukemia;DNA:SNP: :(rs4880)(human)		 CTD
RGD		 PMID:25226513 PMID:20578157 PMID:19332662 PMID:19647030 PMID:27019981 RGD:26923957, RGD:26923959, RGD:26923961, RGD:11060605 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11529661 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sord sorbitol dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12763371 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Sorl1 sortilin related receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Spin2a spindlin family member 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr  X:17,511,018...17,513,001
Ensembl chr  X:17,511,022...17,513,001 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Srp72 signal recognition particle 72 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: therapeutic CTD PMID:38460807 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 severity ISO protein:increased phosphorylation:liver, inflammatory cell (mouse)
mRNA:increased expression:liver, macrophage (mouse)		 RGD PMID:24731448 PMID:23876342 RGD:25671417, RGD:25671422 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 ISO CTD Direct Evidence: therapeutic CTD PMID:36520315 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27052460 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295 		JBrowse link
G Suox sulfite oxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038 		JBrowse link
G Tagln2 transgelin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Taldo1 transaldolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19436114 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tbxa2r thromboxane A2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22206755 NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176 		JBrowse link
G Tctn1 tectonic family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17984051 NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267 		JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO RGD PMID:27516150 RGD:14995464 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28560358 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35357534 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thpo thrombopoietin ISO CTD Direct Evidence: therapeutic CTD PMID:33122006 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Tlr4 toll-like receptor 4 disease_progression IEP RGD PMID:17504260 RGD:14697733 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr5 toll-like receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30508503 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tlr9 toll-like receptor 9 severity
treatment		 ISO protein:increased expression: blood, neutrophil (human) RGD PMID:26457748 PMID:23509352 PMID:19164858 RGD:18337465, RGD:18337473, RGD:18337476 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640 		JBrowse link
G Tmem117 transmembrane protein 117 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 7:125,757,591...126,219,692
Ensembl chr 7:125,757,591...126,219,690 		JBrowse link
G Tmem164 transmembrane protein 164 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr  X:106,288,019...106,448,642
Ensembl chr  X:106,289,371...106,448,640 		JBrowse link
G Tmem38b transmembrane protein 38B ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025 		JBrowse link
G Tnf tumor necrosis factor treatment
severity		 IDA
IEP
ISO
IMP		 protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:7532385 PMID:9696492 PMID:17709330 PMID:19638433 PMID:20623750 More... RGD:10450531, RGD:14696804, RGD:14975281, RGD:14995429, RGD:14995432, RGD:14995435, RGD:14995437, RGD:14995485, RGD:15036799, RGD:15090820 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 ISO RGD PMID:24569808 RGD:9999438 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181 		JBrowse link
G Ttr transthyretin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16099942 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tuba1a tubulin, alpha 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Uba5 ubiquitin-like modifier activating enzyme 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26881866 NCBI chr 8:104,665,241...104,680,915
Ensembl chr 8:104,665,046...104,680,894 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 susceptibility ISO DNA:SNP:exon (rs4148323)(human) RGD PMID:28900877 RGD:14694824 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20623750 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:201,167,388...201,178,343
Ensembl chr 1:201,152,693...201,178,338 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Ust5r integral membrane transport protein UST5r EXP CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 1:205,210,558...205,286,868
Ensembl chr 1:205,211,034...205,286,718 		JBrowse link
G Vegfa vascular endothelial growth factor A treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:25231249 PMID:17784864 RGD:15003197 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vwf von Willebrand factor IEP
ISO		 protein:increased expression:liver:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:28527913 PMID:7531171 RGD:11079232 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wasl WASP like actin nucleation promoting factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr 4:53,083,536...53,132,061
Ensembl chr 4:53,083,536...53,132,022 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility ISO DNA:haploinsufficiency: : (mouse) RGD PMID:21737425 RGD:15036796 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xylb xylulokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231249 NCBI chr 8:119,093,466...119,128,858
Ensembl chr 8:119,096,029...119,128,848 		JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25226513 NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194 		JBrowse link
drug-induced hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 susceptibility
no_association		 ISO DNA:polymorphisms,haplotype:promoter:g.-1774delG,g.-1549G>A(human)
DNA:SNPs:multiple:		 RGD PMID:17502832 PMID:22178260 RGD:14700816, RGD:14700817 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IDA DNA:hypermethylation:promoter RGD PMID:23619520 RGD:14700910 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IDA RGD PMID:16140414 RGD:2316848 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 ISO protein:increased expression:liver (mouse) RGD PMID:12201952 RGD:10054288 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Mir22 microRNA 22 ISO in male; RNA:increased expression:liver: RGD PMID:21750200 RGD:14700876 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
Halothane Hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:28921207 RGD:14975164 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    Chemically-Induced Disorders 1418
      Poisoning 781
        Chemical and Drug Induced Liver Injury 449
          Halothane Hepatitis 1
          drug-induced hepatitis 5
Path 2
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      gastrointestinal system disease 7175
        hepatobiliary disease 3116
          liver disease 3006
            Liver Injury 535
              Chemical and Drug Induced Liver Injury 449
                Halothane Hepatitis 1
                drug-induced hepatitis 5
paths to the root