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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydrazone
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Accession:CHEBI:38532 term browser browse the term
Definition:Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues).
Synonyms:related_synonym: hydrazones



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(E,E)-hydramethylnon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A affects binding
multiple interactions
ISO hydramethylnon binds to ABCB1 protein
hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]
CTD PMID:8917702 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Dio2 deiodinase, iodothyronine, type II decreases activity ISO hydramethylnon results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
carbonyl cyanide p-trifluoromethoxyphenylhydrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18854758 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Lactic Acid]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [AQP9 protein results in increased uptake of Selenious Acid] CTD PMID:28798983 NCBI chr 9:71,017,941...71,075,170
Ensembl chr 9:71,017,941...71,075,964
JBrowse link
G Bax BCL2-associated X protein decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BAX mRNA CTD PMID:16039398 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of BCL2L1 mRNA CTD PMID:16039398 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Casp3 caspase 3 increases activity EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased activity of CASP3 protein CTD PMID:20683024 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CASP8 mRNA CTD PMID:16039398 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CAT mRNA CTD PMID:16039398 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccnc cyclin C decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNC mRNA CTD PMID:16039398 NCBI chr 4:21,727,705...21,759,917
Ensembl chr 4:21,727,701...21,759,922
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCND1 mRNA CTD PMID:16039398 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccng1 cyclin G1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of CCNG1 mRNA CTD PMID:16039398 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Cdk4 cyclin dependent kinase 4 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] CTD PMID:19819288 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789
JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B multiple interactions
increases expression
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein]
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CDKN1B protein
CTD PMID:19819288 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein
[Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased activity of COMT protein] which results in decreased abundance of Adenosine Triphosphate
CTD PMID:14975680 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Coq10a coenzyme Q10A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ10A protein CTD PMID:21308897 NCBI chr10:128,198,965...128,204,849
Ensembl chr10:128,198,969...128,204,866
JBrowse link
G Coq2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ2 mRNA CTD PMID:21308897 NCBI chr 5:100,802,589...100,822,154
Ensembl chr 5:100,802,589...100,823,006
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of COQ3 mRNA CTD PMID:21308897 NCBI chr 4:21,879,646...21,912,163
Ensembl chr 4:21,879,673...21,912,162
JBrowse link
G Coq4 coenzyme Q4 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ4 mRNA CTD PMID:21308897 NCBI chr 2:29,677,505...29,687,947
Ensembl chr 2:29,677,505...29,687,947
JBrowse link
G Coq5 coenzyme Q5 methyltransferase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ5 mRNA CTD PMID:21308897 NCBI chr 5:115,417,752...115,435,029
Ensembl chr 5:115,417,725...115,435,031
JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ6 mRNA CTD PMID:21308897 NCBI chr12:84,408,530...84,420,570
Ensembl chr12:84,408,431...84,420,570
JBrowse link
G Coq7 demethyl-Q 7 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ7 mRNA CTD PMID:21308897 NCBI chr 7:118,108,881...118,132,529
Ensembl chr 7:118,108,882...118,132,579
JBrowse link
G Coq8a coenzyme Q8A increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ8A mRNA CTD PMID:21308897 NCBI chr 1:179,992,803...180,023,585
Ensembl chr 1:179,992,803...180,027,167
JBrowse link
G Coq9 coenzyme Q9 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of COQ9 mRNA CTD PMID:21308897 NCBI chr 8:95,565,041...95,581,523
Ensembl chr 8:95,564,949...95,581,523
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of CYP1A1 mRNA CTD PMID:16039398 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Ddb1 damage specific DNA binding protein 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DDB1 mRNA CTD PMID:16039398 NCBI chr19:10,582,961...10,607,186
Ensembl chr19:10,582,691...10,607,183
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of DNAJA1 mRNA CTD PMID:16039398 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G Egr1 early growth response 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EGR1 mRNA CTD PMID:16039398 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of EPHX2 mRNA CTD PMID:16039398 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Hydroxyl Radical]; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [FMR1 5' UTR mutant form results in increased abundance of Superoxides] CTD PMID:27385396 NCBI chr  X:67,722,144...67,761,569
Ensembl chr  X:67,722,147...67,761,569
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GADD45A mRNA CTD PMID:16039398 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA CTD PMID:16039398 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gsr glutathione reductase decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSR mRNA CTD PMID:16039398 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of GSTM3 mRNA CTD PMID:16039398 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HMOX1 mRNA CTD PMID:16039398 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HMOX2 mRNA CTD PMID:16039398 NCBI chr16:4,544,225...4,584,606
Ensembl chr16:4,544,225...4,584,606
JBrowse link
G Hsf1 heat shock factor 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSF1 mRNA CTD PMID:16039398 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSP90AA1 mRNA CTD PMID:16039398 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Hspa1a heat shock protein 1A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1A mRNA CTD PMID:16039398 NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132
JBrowse link
G Hspa1b heat shock protein 1B decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1B mRNA CTD PMID:16039398 NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214
JBrowse link
G Hspa1l heat shock protein 1-like decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA1L mRNA CTD PMID:16039398 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
JBrowse link
G Hspa2 heat shock protein 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA2 mRNA CTD PMID:16039398 NCBI chr12:76,450,688...76,453,712
Ensembl chr12:76,450,950...76,453,712
JBrowse link
G Hspa4 heat shock protein 4 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA4 mRNA CTD PMID:16039398 NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284
JBrowse link
G Hspa8 heat shock protein 8 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of HSPA8 mRNA CTD PMID:16039398 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of HSPE1 mRNA CTD PMID:16039398 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of ICAM1 mRNA CTD PMID:17416599 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il18 interleukin 18 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA CTD PMID:16039398 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL1A mRNA CTD PMID:16039398 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr11:60,912,970...60,964,095
Ensembl chr11:60,913,390...60,961,957
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [KCNJ4 protein results in increased transport of Potassium] CTD PMID:12118013 NCBI chr15:79,364,427...79,396,712
Ensembl chr15:79,367,915...79,389,442
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA CTD PMID:16039398 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Mt2 metallothionein 2 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MT2A mRNA CTD PMID:16039398 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NFKBIA mRNA CTD PMID:16039398 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nipa1 non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human) decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of NIPA1 mRNA CTD PMID:27157538 NCBI chr 7:55,628,232...55,669,348
Ensembl chr 7:55,627,315...55,669,702
JBrowse link
G Pdss1 prenyl (solanesyl) diphosphate synthase, subunit 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of PDSS1 mRNA CTD PMID:21308897 NCBI chr 2:22,784,393...22,830,273
Ensembl chr 2:22,785,534...22,830,278
JBrowse link
G Pdss2 prenyl (solanesyl) diphosphate synthase, subunit 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PDSS2 mRNA CTD PMID:21308897 NCBI chr10:43,095,396...43,340,878
Ensembl chr10:43,097,482...43,340,878
JBrowse link
G Pink1 PTEN induced putative kinase 1 multiple interactions EXP PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit increases phosphorylation EXP Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions
affects localization
EXP PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of PTGS2 mRNA CTD PMID:16039398 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RAD23A mRNA CTD PMID:16039398 NCBI chr 8:85,561,540...85,567,361
Ensembl chr 8:85,560,648...85,567,294
JBrowse link
G Rpl13a ribosomal protein L13A decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of RPL13A mRNA CTD PMID:16039398 NCBI chr 7:44,774,987...44,778,169
Ensembl chr 7:44,774,982...44,778,185
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNA CTD PMID:16039398 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin] CTD PMID:1438304 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444
JBrowse link
G Slc41a2 solute carrier family 41, member 2 increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SLC41A2 mRNA CTD PMID:27157538 NCBI chr10:83,066,712...83,174,657
Ensembl chr10:83,066,712...83,173,746
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of SOD2 mRNA CTD PMID:16039398 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects response to substance EXP STAT3 protein affects the susceptibility to Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone CTD PMID:20224768 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [TARDBP protein binds to PPP1R15A protein] CTD PMID:29109149 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476
JBrowse link
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 decreases expression ISO Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of XRCC5 mRNA CTD PMID:16039398 NCBI chr 1:72,346,576...72,434,112
Ensembl chr 1:72,346,586...72,434,111
JBrowse link
CCCP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:12130563 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Ambra1 autophagy/beclin 1 regulator 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein] CTD PMID:24879156 NCBI chr 2:91,560,464...91,749,194
Ensembl chr 2:91,560,479...91,749,194
JBrowse link
G Atm ataxia telangiectasia mutated increases phosphorylation
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of ATM protein
ATM protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]
CTD PMID:29660402 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions EXP
ISO
Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]
CTD PMID:24879156 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like multiple interactions
increases phosphorylation
ISO BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4 protein]; BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of BNIP3L protein
CTD PMID:32142837 NCBI chr14:67,222,688...67,246,580
Ensembl chr14:67,222,688...67,246,326
JBrowse link
G Canx calnexin affects localization ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of CANX protein CTD PMID:28940366 NCBI chr11:50,184,784...50,216,500
Ensembl chr11:50,184,788...50,216,500
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein] CTD PMID:33524445 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased cleavage of CASP3 protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]
CTD PMID:24658017 PMID:29241732 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form
DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form]
CTD PMID:29241732 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of CIRBP mRNA CTD PMID:15075239 NCBI chr10:80,001,824...80,008,620
Ensembl chr10:80,001,819...80,008,620
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4I1 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of COX4I1 protein CTD PMID:27318970 NCBI chr 8:121,394,964...121,400,948
Ensembl chr 8:121,394,961...121,400,946
JBrowse link
G Ctsl cathepsin L increases expression EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CTSL mRNA CTD PMID:15978749 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
ISO DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form]; DNM1L protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP9 protein modified form]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of DNM1L protein modified form
CTD PMID:28940366 PMID:29241732 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Eva1a eva-1 homolog A, regulator of programmed cell death multiple interactions ISO [1-Methyl-4-phenylpyridinium co-treated with Carbonyl Cyanide m-Chlorophenyl Hydrazone] results in increased localization of EVA1A protein CTD PMID:36078115 NCBI chr 6:82,018,058...82,070,079
Ensembl chr 6:82,018,024...82,070,080
JBrowse link
G Fasl Fas ligand multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of FASLG mRNA] CTD PMID:24658017 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fkbp5 FK506 binding protein 5 multiple interactions ISO [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein] CTD PMID:30734931 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 multiple interactions
decreases expression
ISO bafilomycin A1 inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of FMC1 protein] CTD PMID:29371327 NCBI chr 6:38,511,796...38,516,384
Ensembl chr 6:38,510,437...38,516,384
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HK2 protein] CTD PMID:34481905 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein
BNIP3L protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of HSPD1 protein]
CTD PMID:32142837 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA] CTD PMID:33524445 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30715550 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LDHA protein] CTD PMID:34481905 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
JBrowse link
G Lep leptin multiple interactions
decreases response to substance
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species]
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased susceptibility to LEP protein
CTD PMID:11342529 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of LONP1 mRNA CTD PMID:28940366 NCBI chr17:56,921,297...56,933,903
Ensembl chr17:56,921,297...56,933,887
JBrowse link
G Mapt microtubule-associated protein tau affects localization ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of MAPT protein CTD PMID:17634376 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and results in increased ubiquitination of MFN2 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of and affects the localization of MFN2 protein
CTD PMID:24879156 PMID:28940366 NCBI chr 4:147,958,043...147,989,527
Ensembl chr 4:147,958,056...147,989,161
JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial decreases expression
multiple interactions
ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein
Deoxyglucose inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of ND1 protein]
CTD PMID:34481905 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein] CTD PMID:30715550 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 increases expression EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of NFKB1 protein CTD PMID:15978749 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta decreases expression EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of NFKBIB protein CTD PMID:15978749 NCBI chr 7:28,457,676...28,466,069
Ensembl chr 7:28,457,676...28,466,937
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of OPA1 protein alternative form CTD PMID:28940366 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 multiple interactions EXP PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] CTD PMID:22872702 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894
JBrowse link
G Pgam5 phosphoglycerate mutase family member 5 multiple interactions ISO PGAM5 protein promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of CASP3 protein modified form] CTD PMID:29241732 NCBI chr 5:110,407,001...110,417,765
Ensembl chr 5:110,406,996...110,417,779
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein] CTD PMID:24879156 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179
JBrowse link
G Pink1 PTEN induced putative kinase 1 multiple interactions
affects localization
increases expression
increases stability
EXP
ISO
PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PINK1 protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein] promotes the reaction [FKBP5 protein binds to PINK1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PINK1 protein binds to ATM protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and affects the localization of PINK1 protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of and results in increased phosphorylation of PINK1 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of PINK1 protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased stability of PINK1 protein
CTD PMID:22872702 PMID:24879156 PMID:26070385 PMID:27318970 PMID:28673964 More... NCBI chr 4:138,040,718...138,053,631
Ensembl chr 4:138,040,720...138,053,618
JBrowse link
G Pkm pyruvate kinase, muscle multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PKM protein] CTD PMID:34481905 NCBI chr 9:59,563,859...59,586,655
Ensembl chr 9:59,563,651...59,586,658
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase affects localization
decreases response to substance
increases response to substance
decreases expression
affects expression
increases phosphorylation
multiple interactions
ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein
PRKN protein results in decreased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone
PRKN gene mutant form results in increased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of PRKN protein
Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form
Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Acetylcysteine inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PARK7 gene mutant form promotes the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; PINK1 gene mutant form inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; PINK1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]
[Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein; BECN1 protein inhibits the reaction [BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [AMBRA1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [BECN1 protein binds to PRKN protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone promotes the reaction [PIK3C3 protein binds to PRKN protein]; Tretinoin affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form]
CTD PMID:16517603 PMID:22872702 PMID:24879156 PMID:26070385 PMID:28673964 More... NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of PTGS2 protein]
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein]
CTD PMID:14514642 PMID:16024921 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rbm3 RNA binding motif (RNP1, RRM) protein 3 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of RBM3 mRNA CTD PMID:15075239 NCBI chr  X:8,005,214...8,012,119
Ensembl chr  X:8,005,214...8,012,119
JBrowse link
G Rel reticuloendotheliosis oncogene increases expression EXP Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased expression of REL protein CTD PMID:15978749 NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of RELA protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of RELA protein] CTD PMID:33524445 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC2A1 protein] CTD PMID:34481905 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [[Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]] which results in decreased activity of NFE2L2 protein; [Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein]] promotes the reaction [KEAP1 protein binds to NFE2L2 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SQSTM1 protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [SQSTM1 protein binds to KEAP1 protein] CTD PMID:30715550 PMID:34481905 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 decreases expression ISO Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of TIMM23 protein CTD PMID:29371327 NCBI chr14:31,902,123...31,923,848
Ensembl chr14:31,902,119...31,923,855
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Testosterone results in increased expression of TNF mRNA]
Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]
CTD PMID:24658017 PMID:33524445 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
dantrolene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) affects transport EXP ABCG2 protein affects the transport of Dantrolene CTD PMID:18322075 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression ISO Dantrolene results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Atf4 activating transcription factor 4 decreases expression
multiple interactions
ISO
EXP
Dantrolene results in decreased expression of ATF4 protein
Dantrolene affects the reaction [perfluorooctanoic acid results in increased expression of ATF4 protein]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Dantrolene promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]
CTD PMID:15921666 PMID:32578922 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of BAX mRNA] CTD PMID:32795494 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Dantrolene results in increased expression of BCL2 protein CTD PMID:10854250 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of BCL2L11 mRNA] CTD PMID:32795494 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions EXP Dantrolene inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein] CTD PMID:16553631 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Capn1 calpain 1 decreases expression ISO Dantrolene results in decreased expression of CAPN1 mRNA; Dantrolene results in decreased expression of CAPN1 protein CTD PMID:11236903 NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927
JBrowse link
G Capn2 calpain 2 decreases expression ISO Dantrolene results in decreased expression of CAPN2 mRNA; Dantrolene results in decreased expression of CAPN2 protein CTD PMID:11236903 NCBI chr 1:182,294,818...182,345,175
Ensembl chr 1:182,294,825...182,345,173
JBrowse link
G Capn3 calpain 3 decreases expression ISO Dantrolene results in decreased expression of CAPN3 mRNA; Dantrolene results in decreased expression of CAPN3 protein CTD PMID:11236903 NCBI chr 2:120,294,074...120,335,400
Ensembl chr 2:120,294,053...120,335,399
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Dantrolene inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]
Dantrolene inhibits the reaction [Indomethacin results in increased activity of CASP3 protein]
CTD PMID:17079870 PMID:23022152 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Dantrolene inhibits the reaction [Indomethacin results in increased activity of CASP9 protein] CTD PMID:23022152 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Dantrolene results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 affects expression ISO Dantrolene affects the expression of CCL5 protein CTD PMID:25051504 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of CXCL2 mRNA] CTD PMID:32795494 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases phosphorylation
multiple interactions
ISO
EXP
Dantrolene results in decreased phosphorylation of DDIT3 protein
Dantrolene inhibits the reaction [Halothane results in increased expression of DDIT3 mRNA]; Dantrolene promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA]; Dantrolene promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 protein]
CTD PMID:15921666 PMID:32578922 PMID:32795494 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Edn1 endothelin 1 decreases activity ISO Dantrolene results in decreased activity of EDN1 protein CTD PMID:12628492 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases phosphorylation ISO Dantrolene results in decreased phosphorylation of EIF2AK3 protein CTD PMID:15921666 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha decreases phosphorylation
multiple interactions
ISO Dantrolene results in decreased phosphorylation of EIF2S1 protein
Dantrolene inhibits the reaction [tributyltin results in increased phosphorylation of EIF2S1 protein]
CTD PMID:15921666 PMID:23743301 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Fkbp1a FK506 binding protein 1a multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of FKBP1A mRNA] CTD PMID:32795494 NCBI chr 2:151,384,403...151,403,611
Ensembl chr 2:151,384,403...151,403,612
JBrowse link
G Fkbp1b FK506 binding protein 1b multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of FKBP1B mRNA] CTD PMID:32795494 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein] CTD PMID:21863293 PMID:21879721 NCBI chr11:102,778,162...102,791,368
Ensembl chr11:102,778,162...102,791,738
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of GPT protein] CTD PMID:32795494 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of HMOX1 mRNA] CTD PMID:32795494 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Homer1 homer scaffolding protein 1 multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of HOMER1 mRNA] CTD PMID:32795494 NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO Dantrolene inhibits the reaction [tributyltin results in increased expression of HSPA5 protein] CTD PMID:23743301 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Ifng interferon gamma multiple interactions EXP Dantrolene inhibits the reaction [taurolithocholic acid 3-sulfate results in increased expression of IFNG mRNA] CTD PMID:22517774 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igf1 insulin-like growth factor 1 decreases response to substance ISO Dantrolene results in decreased susceptibility to IGF1 protein CTD PMID:16485066 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igf2 insulin-like growth factor 2 decreases response to substance ISO Dantrolene results in decreased susceptibility to IGF2 protein CTD PMID:16485066 NCBI chr 7:142,204,505...142,220,566
Ensembl chr 7:142,204,503...142,220,553
JBrowse link
G Il10 interleukin 10 multiple interactions
affects expression
ISO Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]
Dantrolene affects the expression of IL10 protein
CTD PMID:17707769 PMID:25051504 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta affects expression
multiple interactions
ISO
EXP
Dantrolene affects the expression of IL1B mRNA
Dantrolene inhibits the reaction [Halothane results in increased expression of IL1B mRNA]
CTD PMID:25051504 PMID:32795494 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Dantrolene inhibits the reaction [taurolithocholic acid 3-sulfate results in increased expression of IL6 mRNA] CTD PMID:22517774 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Dantrolene results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 multiple interactions EXP Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium] CTD PMID:17189350 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188
JBrowse link
G Lep leptin decreases expression ISO Dantrolene results in decreased expression of LEP protein CTD PMID:25051504 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Ly6g lymphocyte antigen 6 family member G multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of LY6G mRNA] CTD PMID:32795494 NCBI chr15:75,027,110...75,030,977
Ensembl chr15:75,027,089...75,030,975
JBrowse link
G Mef2a myocyte enhancer factor 2A multiple interactions ISO Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A mRNA]; Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A protein] CTD PMID:25093688 NCBI chr 7:66,880,911...67,026,435
Ensembl chr 7:66,880,911...67,022,606
JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions ISO Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2C mRNA]; Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2C protein] CTD PMID:25093688 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199
JBrowse link
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta multiple interactions ISO Dantrolene inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA] CTD PMID:25093688 NCBI chr14:55,208,141...55,232,083
Ensembl chr14:55,208,141...55,232,083
JBrowse link
G Nefl neurofilament, light polypeptide multiple interactions ISO Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 PMID:21879721 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
JBrowse link
G Nefm neurofilament, medium polypeptide multiple interactions ISO Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21863293 PMID:21879721 NCBI chr14:68,356,994...68,362,453
Ensembl chr14:68,320,039...68,362,295
JBrowse link
G Nppa natriuretic peptide type A multiple interactions ISO Dantrolene inhibits the reaction [Caffeine results in increased expression of NPPA mRNA] CTD PMID:25093688 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536
JBrowse link
G Nppb natriuretic peptide type B multiple interactions ISO Dantrolene inhibits the reaction [Caffeine results in increased expression of NPPB mRNA] CTD PMID:25093688 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Ryr1 ryanodine receptor 1, skeletal muscle multiple interactions ISO Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium] CTD PMID:17707769 NCBI chr 7:28,702,765...28,824,599
Ensembl chr 7:28,702,769...28,824,604
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac multiple interactions ISO Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of S100A8 mRNA] CTD PMID:32795494 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of S100A9 mRNA] CTD PMID:32795494 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP Dantrolene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA] CTD PMID:23183170 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO
EXP
Dantrolene results in decreased expression of TNF protein
Dantrolene inhibits the reaction [Halothane results in increased expression of TNF mRNA]
CTD PMID:11236903 PMID:32795494 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP Dantrolene inhibits the reaction [Halothane results in increased expression of VCAM1 mRNA] CTD PMID:32795494 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vim vimentin multiple interactions ISO Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21863293 PMID:21879721 NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637
JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions EXP Dantrolene inhibits the reaction [perfluorooctanoic acid results in increased expression of XBP1 mRNA alternative form]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of XBP1 mRNA alternative form] CTD PMID:32578922 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893
JBrowse link
etazolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 decreases expression
decreases secretion
ISO Etazolate results in decreased expression of IL13 mRNA
Etazolate results in decreased secretion of IL13 protein
CTD PMID:16083514 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Ltc4s leukotriene C4 synthase decreases secretion ISO Etazolate results in decreased secretion of LTC4S protein CTD PMID:16083514 NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443
JBrowse link
hydramethylnon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A affects binding
multiple interactions
ISO hydramethylnon binds to ABCB1 protein
hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]
CTD PMID:8917702 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Dio2 deiodinase, iodothyronine, type II decreases activity ISO hydramethylnon results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
nitrofurazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccne1 cyclin E1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of CCNE1 mRNA] CTD PMID:15945272 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases expression
ISO [Nitrofurazone co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CXCL8 mRNA
Nitrofurazone results in increased expression of CXCL8 mRNA
CTD PMID:29594315 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects binding ISO Nitrofurazone binds to GSK3B protein CTD PMID:18222664 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of HRAS mRNA] CTD PMID:15945272 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA CTD PMID:29594315 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Nitrofurazone results in increased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Nitrofurazone inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of JUN mRNA] CTD PMID:15945272 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Lhb luteinizing hormone beta decreases expression ISO Nitrofurazone results in decreased expression of LHB protein CTD PMID:11548123 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Mir128-1 microRNA 128-1 increases expression ISO Nitrofurazone results in increased expression of MIR128-1 mRNA CTD PMID:32418910 NCBI chr 1:128,130,098...128,130,167
Ensembl chr 1:128,130,098...128,130,167
JBrowse link
G Myc myelocytomatosis oncogene increases expression
multiple interactions
ISO Nitrofurazone results in increased expression of MYC mRNA
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of MYC mRNA]
CTD PMID:15945272 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO [Nitrofurazone co-treated with POR protein co-treated with Copper] results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; Nitrofurazone inhibits the reaction [POR protein results in increased metabolism of Misonidazole] CTD PMID:6802140 PMID:15488632 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Prl prolactin decreases expression ISO Nitrofurazone results in decreased expression of PRL protein CTD PMID:11548123 NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188
JBrowse link
G Tgfa transforming growth factor alpha increases expression
multiple interactions
ISO Nitrofurazone results in increased expression of TGFA mRNA
Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of TGFA mRNA]
CTD PMID:15945272 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of TNF mRNA] CTD PMID:15945272 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 increases mutagenesis ISO Nitrofurazone results in increased mutagenesis of TP53 gene CTD PMID:15488632 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
rifampicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700011L22Rik RIKEN cDNA 1700011L22 gene decreases expression ISO Rifampin results in decreased expression of C4ORF51 mRNA CTD PMID:24552687 NCBI chr 8:79,937,059...79,975,212
Ensembl chr 8:79,937,060...79,975,199
JBrowse link
G 4921517D22Rik RIKEN cDNA 4921517D22 gene decreases expression ISO Rifampin results in decreased expression of C9ORF153 mRNA CTD PMID:24552687 NCBI chr13:59,835,216...59,841,917
Ensembl chr13:59,835,216...59,841,922
JBrowse link
G Aadac arylacetamide deacetylase multiple interactions
increases hydrolysis
decreases acetylation
ISO AADAC mRNA affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Isoflurophate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Phenylmethylsulfonyl Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Sodium Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]
AADAC protein results in increased hydrolysis of Rifampin
CTD PMID:21856291 PMID:22207054 NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 decreases expression
increases expression
ISO Rifampin results in decreased expression of ABCA1 mRNA; Rifampin results in decreased expression of ABCA1 protein
Rifampin results in increased expression of ABCA1 mRNA; Rifampin results in increased expression of ABCA1 protein
CTD PMID:15883047 PMID:17088262 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abca2 ATP-binding cassette, sub-family A member 2 increases expression ISO Rifampin results in increased expression of ABCA2 mRNA CTD PMID:27199754 NCBI chr 2:25,318,611...25,338,556
Ensembl chr 2:25,318,715...25,338,552
JBrowse link
G Abca8b ATP-binding cassette, sub-family A member 8b decreases expression ISO Rifampin results in decreased expression of ABCA8 mRNA CTD PMID:27199754 NCBI chr11:109,823,016...109,886,642
Ensembl chr11:109,823,016...109,886,671
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases expression
multiple interactions
decreases activity
ISO
EXP
Rifampin results in decreased expression of ABCB11 mRNA
Rifampin results in decreased expression of ABCB11 protein
[Rifampin co-treated with Isoniazid] results in decreased expression of ABCB11 protein
tanshinone inhibits the reaction [Rifampin results in decreased expression of ABCB11 mRNA]; tanshinone inhibits the reaction [Rifampin results in decreased expression of ABCB11 protein]
Rifampin results in decreased activity of ABCB11 protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of ABCB11 protein; Rifampin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Rifampin results in decreased expression of ABCB11 mRNA; Rifampin results in decreased expression of ABCB11 protein
CTD PMID:12135489 PMID:16837569 PMID:20829430 PMID:24014644 PMID:25886055 More... NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A affects activity
increases expression
multiple interactions
decreases activity
ISO Rifampin affects the activity of ABCB1 protein
Rifampin results in increased expression of ABCB1 mRNA; Rifampin results in increased expression of ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate
[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]; Rifampin promotes the reaction [NR1I2 protein binds to ABCB1 promoter]
CTD PMID:8632764 PMID:11744607 PMID:14722322 PMID:15276086 PMID:15290871 More... NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 increases expression ISO Rifampin results in increased expression of ABCB4 mRNA CTD PMID:27199754 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcb6 ATP-binding cassette, sub-family B member 6 increases expression ISO Rifampin results in increased expression of ABCB6 mRNA CTD PMID:27199754 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases expression ISO Rifampin results in increased expression of ABCC1 mRNA CTD PMID:17191263 PMID:35972551 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc10 ATP-binding cassette, sub-family C member 10 increases expression ISO Rifampin results in increased expression of ABCC10 mRNA CTD PMID:27199754 NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 affects export
multiple interactions
increases expression
ISO ABCC2 protein affects the export of Rifampin
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of ABCC2 protein
Rifampin results in increased expression of ABCC2; Rifampin results in increased expression of ABCC2 mRNA; Rifampin results in increased expression of ABCC2 protein
[Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein
CTD PMID:11836020 PMID:12206135 PMID:15652233 PMID:16837569 PMID:16952291 More... NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions
increases expression
increases activity
ISO [Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; Rifampin inhibits the reaction [decitabine results in increased expression of ABCC3 mRNA]
Rifampin results in increased expression of ABCC3 mRNA
Rifampin results in increased activity of ABCC3 protein
CTD PMID:14570758 PMID:16837569 PMID:16952291 PMID:19041851 PMID:20832446 More... NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 increases expression ISO Rifampin results in increased expression of ABCC5 mRNA CTD PMID:19041851 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 increases expression ISO Rifampin results in increased expression of ABCC6 mRNA CTD PMID:27199754 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
JBrowse link
G Abcf1 ATP-binding cassette, sub-family F member 1 increases expression ISO Rifampin results in increased expression of ABCF1 mRNA CTD PMID:27199754 NCBI chr17:36,267,711...36,280,642
Ensembl chr17:36,267,711...36,280,653
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Rifampin results in increased expression of ABCG1 mRNA; Rifampin results in increased expression of ABCG1 protein CTD PMID:12040753 PMID:17088262 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression ISO Rifampin results in increased expression of ABCG2 mRNA CTD PMID:16837569 PMID:27199754 PMID:35972551 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Rifampin results in increased expression of ABCG8 mRNA CTD PMID:27199754 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Abi3 ABI family member 3 decreases expression ISO Rifampin results in decreased expression of ABI3 mRNA CTD PMID:24552687 NCBI chr11:95,720,898...95,733,302
Ensembl chr11:95,720,900...95,733,302
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases expression EXP Rifampin results in increased expression of ACACA mRNA CTD PMID:27806127 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Rifampin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein CTD PMID:36878459 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531
JBrowse link
G Actr10 ARP10 actin-related protein 10 increases expression ISO Rifampin results in increased expression of ACTR10 mRNA CTD PMID:24552687 NCBI chr12:70,984,631...71,011,492
Ensembl chr12:70,984,631...71,011,492
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Rifampin results in increased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of ADIPOQ mRNA CTD PMID:33412187 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Rifampin results in decreased expression of ADORA2A mRNA CTD PMID:24552687 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 decreases expression ISO Rifampin results in decreased expression of AGAP2 mRNA CTD PMID:24552687 NCBI chr10:126,911,154...126,929,039
Ensembl chr10:126,911,153...126,929,038
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases expression
ISO [Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in decreased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of AHR protein; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]
Rifampin results in increased expression of AHR mRNA; Rifampin results in increased expression of AHR protein
CTD PMID:22733800 PMID:28428138 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Akr1b10 aldo-keto reductase family 1, member B10 multiple interactions
increases expression
ISO pazopanib inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA] CTD PMID:29356861 NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885
JBrowse link
G Alas1 aminolevulinic acid synthase 1 increases expression ISO Rifampin results in increased expression of ALAS1 mRNA CTD PMID:24259679 PMID:24552687 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions
increases activity
EXP [Rifampin co-treated with Isoniazid] results in increased activity of ALPL protein
Rifampin results in increased activity of ALPL protein
CTD PMID:25886055 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Rifampin results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 4:98,919,191...98,926,429
Ensembl chr 4:98,919,191...98,934,348
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA CTD PMID:21127053 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression ISO Rifampin results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:94,218,827...94,232,673
Ensembl chr11:94,218,827...94,232,667
JBrowse link
G Ankrd65 ankyrin repeat domain 65 decreases expression ISO Rifampin results in decreased expression of ANKRD65 mRNA CTD PMID:24552687 NCBI chr 4:155,875,432...155,884,132
Ensembl chr 4:155,874,896...155,877,659
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Rifampin results in decreased expression of ANKS1B mRNA CTD PMID:24552687 NCBI chr10:89,707,238...90,809,162
Ensembl chr10:89,709,371...90,809,162
JBrowse link
G Anxa5 annexin A5 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA CTD PMID:21224054 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Apob apolipoprotein B decreases expression
multiple interactions
affects secretion
ISO Rifampin results in decreased expression of APOB mRNA
ursodoxicoltaurine inhibits the reaction [Rifampin results in decreased expression of APOB mRNA]
Rifampin affects the secretion of APOB protein
CTD PMID:32535746 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
JBrowse link
G Apoc3 apolipoprotein C-III decreases secretion
decreases expression
ISO Rifampin results in decreased secretion of APOC3 protein
Rifampin results in decreased expression of APOC3 mRNA
CTD PMID:32535746 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
JBrowse link
G Aqp3 aquaporin 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA CTD PMID:21127053 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO Rifampin results in decreased expression of AQP4 mRNA CTD PMID:24552687 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039
JBrowse link
G Arsj arylsulfatase J decreases expression ISO Rifampin results in decreased expression of ARSJ mRNA CTD PMID:24552687 NCBI chr 3:126,157,566...126,234,025
Ensembl chr 3:126,157,333...126,234,024
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions EXP [Rifampin co-treated with Cobicistat] results in increased expression of ATF3 mRNA CTD PMID:33629115 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
Rifampin results in increased expression of ATF4 mRNA; Rifampin results in increased expression of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 protein]
CTD PMID:24638036 PMID:27470132 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Rifampin results in increased expression of ATF6 mRNA CTD PMID:32535746 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein
Rifampin results in decreased expression of ATM mRNA
CTD PMID:21224054 PMID:24552687 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 increases expression
multiple interactions
ISO Rifampin results in increased expression of ATP6V0A1 protein
[Rotenone co-treated with Rifampin] results in increased expression of ATP6V0A1 protein; Rifampin inhibits the reaction [Rotenone results in decreased expression of ATP6V0A1 mRNA]; Rotenone inhibits the reaction [Rifampin results in increased expression of ATP6V0A1 protein]
CTD PMID:31648047 NCBI chr11:100,899,262...100,954,545
Ensembl chr11:100,900,278...100,954,545
JBrowse link
G Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1 multiple interactions ISO ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]] CTD PMID:31648047 NCBI chr 8:106,251,093...106,292,696
Ensembl chr 8:106,251,097...106,292,679
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Rifampin results in increased expression of ATRX mRNA CTD PMID:24552687 NCBI chr  X:104,841,221...104,972,978
Ensembl chr  X:104,841,221...104,973,009
JBrowse link
G Bax BCL2-associated X protein multiple interactions
decreases expression
EXP
ISO
[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of BAX mRNA; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein]
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein
Rifampin results in decreased expression of BAX protein
CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:21419764 PMID:31629065 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression
multiple interactions
ISO
EXP
Rifampin results in increased expression of BCL2 protein
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein
[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein]
CTD PMID:11958592 PMID:21419764 PMID:31629065 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
multiple interactions
ISO
EXP
Rifampin results in increased expression of BCL2L1 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA
CTD PMID:11958592 PMID:12645856 PMID:21224054 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA CTD PMID:21127053 NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA CTD PMID:21127053 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression ISO Rifampin results in decreased expression of CA1 mRNA CTD PMID:24552687 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Casp1 caspase 1 multiple interactions EXP Rifampin inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein] CTD PMID:26086368 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [Staurosporine results in increased cleavage of CASP3 protein]; Rifampin promotes the reaction [Galactosamine results in increased activity of CASP3 protein]
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of CASP3
[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]
CTD PMID:11958592 PMID:12645856 PMID:17936189 PMID:21419764 PMID:23764483 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:11958592 PMID:12645856 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of CAT protein CTD PMID:36878459 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbr3 carbonyl reductase 3 multiple interactions EXP [Rifampin co-treated with Cobicistat] results in increased expression of CBR3 mRNA CTD PMID:33629115 NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Rifampin results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Rifampin results in decreased expression of CCL5 protein CTD PMID:25051504 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA CTD PMID:21127053 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA CTD PMID:21224054 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccng1 cyclin G1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA CTD PMID:21224054 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA CTD PMID:21127053 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA CTD PMID:21127053 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
JBrowse link
G Cd36 CD36 molecule increases expression EXP Rifampin results in increased expression of CD36 mRNA CTD PMID:27806127 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA CTD PMID:21127053 NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of CEBPA mRNA; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA protein] CTD PMID:33412187 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of CEBPB mRNA; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB protein] CTD PMID:33412187 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of CEBPD mRNA; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPD mRNA] CTD PMID:33412187 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Rifampin results in increased expression of CES1 protein CTD PMID:10640517 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2a carboxylesterase 2A multiple interactions EXP [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA CTD PMID:22467028 NCBI chr 8:105,460,635...105,468,266
Ensembl chr 8:105,460,635...105,468,266
JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions
ISO Rifampin results in increased expression of CES2 mRNA; Rifampin results in increased expression of CES2 protein
Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]
CTD PMID:10640517 PMID:17003103 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression
ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]
Rifampin results in increased expression of CFLAR protein
CTD PMID:11958592 PMID:12645856 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA CTD PMID:21224054 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 decreases expression ISO Rifampin results in decreased expression of CIZ1 mRNA CTD PMID:24552687 NCBI chr 2:32,252,724...32,268,311
Ensembl chr 2:32,242,339...32,270,982
JBrowse link
G Clk2 CDC-like kinase 2 decreases expression ISO Rifampin results in decreased expression of CLK2 mRNA CTD PMID:24552687 NCBI chr 3:89,072,102...89,084,394
Ensembl chr 3:89,072,102...89,084,228
JBrowse link
G Cntln centlein, centrosomal protein increases expression ISO Rifampin results in increased expression of CNTLN mRNA CTD PMID:24552687 NCBI chr 4:84,800,024...85,050,160
Ensembl chr 4:84,802,546...85,050,158
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression EXP Rifampin results in increased expression of CPT1A mRNA CTD PMID:27806127 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 decreases expression ISO Rifampin results in decreased expression of CRHR1 mRNA CTD PMID:24552687 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions ISO [Floxacillin co-treated with Gentamicins co-treated with Rifampin] results in increased expression of CRP protein CTD PMID:16943303 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 decreases expression ISO Rifampin results in decreased expression of CSNK1G1 mRNA CTD PMID:24552687 NCBI chr 9:65,816,235...65,952,297
Ensembl chr 9:65,816,206...65,952,297
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO Rifampin results in increased expression of CXCL1 protein CTD PMID:25051504 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
affects expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA
Rifampin affects the expression of CXCL10 protein
CTD PMID:21224054 PMID:25051504 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cyb5rl cytochrome b5 reductase-like increases expression ISO Rifampin results in increased expression of CYB5RL mRNA CTD PMID:24552687 NCBI chr 4:106,924,035...106,945,204
Ensembl chr 4:106,924,185...106,945,465
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression
ISO Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Rifampin results in increased activity of CYP1A1 protein
Rifampin results in increased expression of CYP1A1 mRNA; Rifampin results in increased expression of CYP1A1 protein
[Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP1A1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 protein; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A1 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:12040753 PMID:18493746 PMID:19118567 PMID:19409404 PMID:22733800 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO
EXP
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Rifampin results in increased expression of CYP1A2 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein
Rifampin results in increased expression of CYP1A2 mRNA; Rifampin results in increased expression of CYP1A2 protein
CTD PMID:15977188 PMID:17590308 PMID:18493746 PMID:25835148 PMID:29162470 More... NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1B1 mRNA
CTD PMID:21224054 PMID:29162470 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]
Rifampin results in increased activity of CYP24A1 protein
CTD PMID:15630458 PMID:21127053 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA CTD PMID:21127053 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]
Rifampin results in increased expression of CYP27A1 mRNA
CTD PMID:17088262 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 increases expression ISO Rifampin results in increased expression of CYP2A1 mRNA CTD PMID:19118567 NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 increases expression EXP Rifampin results in increased expression of CYP2A4 mRNA CTD PMID:30503582 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 multiple interactions
increases expression
increases activity
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA
Rifampin results in increased expression of CYP2A6 mRNA; Rifampin results in increased expression of CYP2A6 protein
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP2A6 mRNA; Rifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [PPARGC1A protein binds to CYP2A6 promoter]
Rifampin results in increased expression of CYP2A5 mRNA
Rifampin results in increased activity of CYP2A5 protein
CTD PMID:11038160 PMID:14709624 PMID:15629111 PMID:16857725 PMID:19118567 More... NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression
increases activity
EXP
ISO
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA
Rifampin results in increased expression of CYP2B10 mRNA
Rifampin results in increased expression of CYP2B6 mRNA; Rifampin results in increased expression of CYP2B6 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2B6 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Dexamethasone promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; GW 3965 inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP2B6 protein
Rifampin results in increased activity of CYP2B6 protein
CTD PMID:12040753 PMID:12571232 PMID:12695351 PMID:14709624 PMID:14977870 More... NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 multiple interactions
decreases expression
EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA
Rifampin results in decreased expression of CYP2B9 mRNA
CTD PMID:21224054 PMID:30503582 NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 multiple interactions
increases expression
affects binding
increases activity
EXP
ISO
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein
Rifampin results in increased expression of CYP2C29 mRNA
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]
Rifampin results in increased expression of CYP2C8 mRNA; Rifampin results in increased expression of CYP2C8 protein
[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter
Rifampin results in increased activity of CYP2C8 protein
CTD PMID:12040753 PMID:15771232 PMID:15933212 PMID:17954527 PMID:19118567 More... NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 increases expression EXP Rifampin results in increased expression of CYP2C37 mRNA CTD PMID:30503582 NCBI chr19:39,980,868...40,000,687
Ensembl chr19:39,980,868...40,000,687
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions
increases activity
increases expression
ISO Rifampin results in increased expression of and results in increased activity of CYP2C19 protein
Rifampin results in increased activity of CYP2C19 protein
Rifampin results in increased expression of CYP2C19 mRNA; Rifampin results in increased expression of CYP2C19 protein
CTD PMID:12584154 PMID:14709624 PMID:15629111 PMID:17954527 PMID:19118567 More... NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene decreases expression ISO Rifampin results in decreased expression of CYP2C18 mRNA; Rifampin results in decreased expression of CYP2C18 protein CTD PMID:22258563 PMID:31629065 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
affects response to substance
increases expression
increases activity
ISO Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin results in increased activity of and results in increased expression of CYP2C9 protein; Rifampin results in increased expression of and results in increased activity of CYP2C9 protein
CYP2C9 alternative form affects the susceptibility to Rifampin
Rifampin results in increased expression of CYP2C9 mRNA; Rifampin results in increased expression of CYP2C9 protein
Rifampin results in increased activity of CYP2C9 protein
CTD PMID:14600250 PMID:14709624 PMID:14722322 PMID:15629111 PMID:15802389 More... NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases expression
increases activity
decreases expression
ISO
EXP
Rifampin results in increased expression of CYP2D6 mRNA
Rifampin results in increased activity of CYP2D6 protein
Rifampin results in decreased expression of CYP2D22 mRNA
CTD PMID:19041851 PMID:30503582 PMID:33844597 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2d9 cytochrome P450, family 2, subfamily d, polypeptide 9 decreases expression EXP Rifampin results in decreased expression of CYP2D9 mRNA CTD PMID:30503582 NCBI chr15:82,336,578...82,341,028
Ensembl chr15:82,317,638...82,341,046
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
decreases expression
multiple interactions
increases expression
ISO
EXP
Rifampin results in increased activity of CYP2E1 protein
Rifampin results in decreased expression of CYP2E1 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein
Rifampin results in increased expression of CYP2E1 mRNA; Rifampin results in increased expression of CYP2E1 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein; [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]
CTD PMID:15132840 PMID:18071298 PMID:22258563 PMID:22733800 PMID:25835148 More... NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 decreases expression ISO Rifampin results in decreased expression of CYP2F1 mRNA CTD PMID:22258563 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 decreases expression ISO Rifampin results in decreased expression of CYP2J2 mRNA CTD PMID:33263786 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA CTD PMID:21127053 NCBI chr 7:25,501,894...25,515,950
Ensembl chr 7:25,501,900...25,516,338
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions
increases expression
EXP [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; sulforaphane inhibits the reaction [Rifampin results in increased expression of CYP3A11 mRNA]
Rifampin results in increased expression of CYP3A11 mRNA; Rifampin results in increased expression of CYP3A11 protein
CTD PMID:20869979 PMID:21224054 PMID:22467028 PMID:23153560 PMID:25835148 More... NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 increases expression ISO Rifampin results in increased expression of CYP3A7 mRNA
Rifampin results in increased expression of CYP3A5 mRNA
CTD PMID:12040753 PMID:12673034 PMID:15629111 PMID:15681896 PMID:19118567 More... NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 increases activity
multiple interactions
EXP Rifampin results in increased activity of CYP3A4 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]
CTD PMID:20361990 PMID:21224054 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684
JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 multiple interactions
increases expression
EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A10 mRNA
Rifampin results in increased expression of CYP4A10 mRNA
CTD PMID:21224054 PMID:27806127 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions
increases expression
EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A14 mRNA
Rifampin results in increased expression of CYP4A14 mRNA
CTD PMID:21224054 PMID:27806127 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of CYP7A1 protein
Rifampin results in decreased expression of CYP7A1 mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of CYP7A1 protein; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]
CTD PMID:15629111 PMID:21127053 PMID:21224054 PMID:22258563 PMID:24259679 More... NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA CTD PMID:21127053 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 decreases expression ISO Rifampin results in decreased expression of DCAF5 mRNA CTD PMID:24552687 NCBI chr12:80,382,622...80,483,375
Ensembl chr12:80,382,622...80,483,375
JBrowse link
G Dclre1b DNA cross-link repair 1B decreases expression ISO Rifampin results in decreased expression of DCLRE1B mRNA CTD PMID:24552687 NCBI chr 3:103,707,921...103,716,703
Ensembl chr 3:103,707,921...103,716,760
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of DDIT3 mRNA
Rifampin results in increased expression of DDIT3 mRNA; Rifampin results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of DDIT3 mRNA]
CTD PMID:21224054 PMID:27470132 PMID:32535746 PMID:33629115 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA CTD PMID:22101211 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dio1 deiodinase, iodothyronine, type I increases expression ISO Rifampin results in increased expression of DIO1 mRNA CTD PMID:24552687 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Dlx4 distal-less homeobox 4 decreases expression ISO Rifampin results in decreased expression of DLX4 mRNA CTD PMID:24552687 NCBI chr11:95,031,273...95,037,116
Ensembl chr11:95,031,273...95,037,089
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA CTD PMID:21224054 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA CTD PMID:21127053 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA
CTD PMID:21127053 PMID:21224054 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA CTD PMID:21127053 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Egr4 early growth response 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA CTD PMID:21127053 NCBI chr 6:85,488,103...85,490,571
Ensembl chr 6:85,488,103...85,490,571
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
multiple interactions
increases expression
ISO Rifampin results in increased phosphorylation of EIF2AK3 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 protein]
Rifampin results in increased expression of EIF2AK3 mRNA; Rifampin results in increased expression of EIF2AK3 protein
CTD PMID:24638036 PMID:27470132 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation ISO Rifampin results in increased phosphorylation of EIF2S1 protein CTD PMID:24638036 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Elk1 ELK1, member of ETS oncogene family decreases expression ISO Rifampin results in decreased expression of ELK1 mRNA CTD PMID:24552687 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression
multiple interactions
ISO Rifampin results in increased expression of EPHX1 mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA]
CTD PMID:22258563 PMID:25313206 PMID:29356861 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions
increases expression
ISO Rifampin results in increased expression of and results in increased phosphorylation of ERN1 protein
Rifampin results in increased expression of ERN1 mRNA
CTD PMID:32535746 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Etnppl ethanolamine phosphate phospholyase increases expression ISO Rifampin results in increased expression of ETNPPL mRNA CTD PMID:24552687 NCBI chr 3:130,411,097...130,429,399
Ensembl chr 3:130,411,097...130,431,170
JBrowse link
G F13b coagulation factor XIII, beta subunit increases expression ISO Rifampin results in increased expression of F13B mRNA CTD PMID:24552687 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein] CTD PMID:11958592 PMID:12645856 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA
Rifampin results in decreased expression of FASLG mRNA; Rifampin results in decreased expression of FASLG protein
Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]
CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:24552687 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase increases expression
affects expression
multiple interactions
EXP
ISO
Rifampin results in increased expression of FASN mRNA
Rifampin affects the expression of FASN mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of FASN mRNA]
CTD PMID:27806127 PMID:29356861 PMID:34689256 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fgf15 fibroblast growth factor 15 multiple interactions
increases expression
ISO [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA
Rifampin results in increased expression of FGF19 mRNA
CTD PMID:17696253 NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
JBrowse link
G Fmo1 flavin containing monooxygenase 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA CTD PMID:21224054 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
JBrowse link
G Fmo4 flavin containing monooxygenase 4 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA CTD PMID:21224054 NCBI chr 1:162,620,757...162,643,788
Ensembl chr 1:162,620,757...162,641,541
JBrowse link
G Foxa1 forkhead box A1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA CTD PMID:21127053 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702
JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Rifampin results in increased expression of FOXP1 mRNA CTD PMID:24552687 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682
JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO Rifampin results in decreased expression of FUT1 mRNA CTD PMID:24552687 NCBI chr 7:45,266,862...45,270,483
Ensembl chr 7:45,266,713...45,270,483
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
decreases expression
affects expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]
Rifampin results in decreased expression of G6PC1 mRNA
CTD PMID:24204015 PMID:34689256 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA CTD PMID:21224054 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA] CTD PMID:21127053 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
JBrowse link
G Gata5 GATA binding protein 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA CTD PMID:21127053 NCBI chr 2:179,966,881...179,977,296
Ensembl chr 2:179,966,926...179,976,492
JBrowse link
G Gck glucokinase decreases expression
multiple interactions
ISO Rifampin results in decreased expression of GCK protein
NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]
CTD PMID:26616219 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Rifampin results in increased expression of GLIS2 mRNA CTD PMID:24552687 NCBI chr16:4,412,217...4,443,076
Ensembl chr16:4,412,577...4,442,788
JBrowse link
G Gm14295 predicted gene 14295 increases expression ISO Rifampin results in increased expression of ZNF441 mRNA CTD PMID:24552687 NCBI chr 2:176,489,972...176,512,508
Ensembl chr 2:176,490,405...176,503,016
JBrowse link
G Gm24031 predicted gene, 24031 decreases expression ISO Rifampin results in decreased expression of SNORA71C mRNA CTD PMID:24552687 NCBI chr14:26,218,810...26,218,940
Ensembl chr14:26,218,810...26,218,940
JBrowse link
G Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type decreases expression ISO Rifampin results in decreased expression of GNAL mRNA CTD PMID:24552687 NCBI chr18:67,221,369...67,359,863
Ensembl chr18:67,221,287...67,359,863
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions
increases activity
EXP [Rifampin co-treated with Isoniazid] results in increased activity of GOT1 protein
Rifampin results in increased activity of GOT1 protein
CTD PMID:25886055 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions
increases activity
increases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of GPT protein]; [Rifampin co-treated with Acetaminophen] results in decreased activity of GPT protein
Rifampin results in increased activity of GPT protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPT protein; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein]
[Rifampin co-treated with Isoniazid] results in increased activity of GPT protein; Rifampin inhibits the reaction [Acetaminophen results in increased expression of GPT protein]
CTD PMID:24685772 PMID:25886055 PMID:27470132 PMID:31678598 PMID:35544702 More... NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of GPX2 mRNA CTD PMID:21224054 PMID:33629115 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein] CTD PMID:36878459 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) decreases expression ISO Rifampin results in decreased expression of GRIA1 mRNA CTD PMID:24552687 NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070
JBrowse link
G Gsr glutathione reductase increases activity EXP Rifampin results in increased activity of GSR protein CTD PMID:20848779 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein CTD PMID:21224054 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA CTD PMID:21224054 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression
multiple interactions
ISO Rifampin results in increased expression of GSTP1 mRNA; Rifampin results in increased expression of GSTP1 protein
[Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 protein
CTD PMID:22733800 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 multiple interactions ISO GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin]; GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide] CTD PMID:18397238 PMID:20485159 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 increases expression ISO Rifampin results in increased expression of GTF2IRD2 mRNA CTD PMID:24552687 NCBI chr 5:134,211,629...134,246,988
Ensembl chr 5:134,212,858...134,253,209
JBrowse link
G Gzmb granzyme B increases secretion ISO Rifampin results in increased secretion of GZMB protein CTD PMID:27933861 NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 affects expression ISO Rifampin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-DMa histocompatibility 2, class II, locus DMa increases expression ISO Rifampin results in increased expression of HLA-DMA mRNA CTD PMID:24552687 NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 affects expression ISO Rifampin affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA CTD PMID:21127053 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA CTD PMID:21127053 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992
JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA CTD PMID:21127053 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316
JBrowse link
G Hgf hepatocyte growth factor multiple interactions EXP HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species]; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] CTD PMID:23764483 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of HIF1A mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of HIF1A protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein]; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein]; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein]
CTD PMID:21127053 PMID:36878459 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgn5 high-mobility group nucleosome binding domain 5 increases expression ISO Rifampin results in increased expression of HMGN5 mRNA CTD PMID:24552687 NCBI chr  X:108,048,143...108,056,986
Ensembl chr  X:108,048,140...108,057,010
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA
dorsomorphin inhibits the reaction [Rifampin results in increased expression of HMOX1 protein]
Rifampin results in increased expression of HMOX1 mRNA; Rifampin results in increased expression of HMOX1 protein
[arsenite co-treated with Rifampin] results in increased expression of HMOX1 mRNA
CTD PMID:21224054 PMID:22159698 PMID:22258563 PMID:31678598 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha multiple interactions ISO [HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:21127053 PMID:21292004 PMID:21764778 PMID:25069801 NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
JBrowse link
G Hrh1 histamine receptor H1 increases expression ISO Rifampin results in increased expression of HRH1 mRNA CTD PMID:24552687 NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Hspa1l heat shock protein 1-like multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA CTD PMID:21224054 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
increases expression
ISO
EXP
ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
[Rifampin co-treated with Cobicistat] results in increased expression of HSPA5 mRNA
Rifampin results in increased expression of HSPA5 mRNA; Rifampin results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
CTD PMID:24638036 PMID:27470132 PMID:32535746 PMID:33629115 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspb1 heat shock protein 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA CTD PMID:21224054 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA CTD PMID:21224054 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA CTD PMID:21224054 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
JBrowse link
G Ifng interferon gamma increases secretion ISO Rifampin results in increased secretion of IFNG protein CTD PMID:27933861 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA CTD PMID:21127053 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA CTD PMID:21127053 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA CTD PMID:21127053 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
JBrowse link
G Il10 interleukin 10 affects expression ISO Rifampin affects the expression of IL10 protein CTD PMID:25051504 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 decreases expression ISO Rifampin results in decreased expression of IL12RB2 mRNA CTD PMID:24552687 NCBI chr 6:67,263,914...67,353,277
Ensembl chr 6:67,268,302...67,353,172
JBrowse link
G Il13 interleukin 13 increases secretion ISO Rifampin results in increased secretion of IL13 protein CTD PMID:27933861 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il18 interleukin 18 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; Rifampin inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Rifampin results in decreased expression of IL1B mRNA; Rifampin results in decreased expression of IL1B protein
CTD PMID:21224054 PMID:25051504 PMID:26086368 PMID:31648047 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
increases expression
ISO
EXP
Rifampin results in decreased expression of IL6 protein
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]
Rifampin results in increased expression of IL6 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA
CTD PMID:21224054 PMID:21357946 PMID:25051504 PMID:31648047 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ino80d INO80 complex subunit D decreases expression ISO Rifampin results in decreased expression of INO80D mRNA CTD PMID:24552687 NCBI chr 1:63,086,960...63,153,693
Ensembl chr 1:62,997,577...63,153,849
JBrowse link
G Ins2 insulin II multiple interactions ISO
EXP
INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]
Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA protein]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB protein]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPD mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA alternative form]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG protein]
CTD PMID:24204015 PMID:33412187 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO Rifampin results in decreased expression of INTS6 mRNA CTD PMID:24552687 NCBI chr14:62,913,774...62,998,617
Ensembl chr14:62,913,779...62,998,618
JBrowse link
G Iqca1 IQ motif containing with AAA domain 1 decreases expression ISO Rifampin results in decreased expression of IQCA1 mRNA CTD PMID:24552687 NCBI chr 1:89,969,854...90,081,158
Ensembl chr 1:89,969,854...90,081,123
JBrowse link
G Itgbl1 integrin, beta-like 1 decreases expression ISO Rifampin results in decreased expression of ITGBL1 mRNA CTD PMID:24552687 NCBI chr14:123,897,331...124,215,173
Ensembl chr14:123,897,383...124,213,030
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA CTD PMID:21127053 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression ISO Rifampin results in decreased expression of KIRREL3 mRNA CTD PMID:24552687 NCBI chr 9:34,396,850...34,952,103
Ensembl chr 9:34,397,190...34,948,012
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA CTD PMID:21127053 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Klf5 Kruppel-like transcription factor 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA CTD PMID:21127053 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Klf6 Kruppel-like transcription factor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA CTD PMID:21127053 NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
JBrowse link
G Ldlr low density lipoprotein receptor increases expression EXP Rifampin results in increased expression of LDLR mRNA CTD PMID:27806127 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lefty1 left right determination factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA CTD PMID:21127053 NCBI chr 1:180,762,587...180,765,966
Ensembl chr 1:180,762,587...180,765,965
JBrowse link
G Lep leptin increases expression ISO Rifampin results in increased expression of LEP protein CTD PMID:25051504 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Ltk leukocyte tyrosine kinase increases expression ISO Rifampin results in increased expression of LTK mRNA CTD PMID:24552687 NCBI chr 2:119,581,807...119,590,912
Ensembl chr 2:119,581,801...119,590,912
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA CTD PMID:21127053 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases metabolic processing
multiple interactions
increases lipidation
ISO Rifampin results in decreased metabolism of MAP1LC3B protein
ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]]; Chloroquine promotes the reaction [Rifampin results in increased lipidation of MAP1LC3B protein]; Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]
CTD PMID:29908302 PMID:31648047 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]]; Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 increases phosphorylation ISO Rifampin results in increased phosphorylation of MAPKAPK2 protein CTD PMID:21127053 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 increases expression ISO Rifampin results in increased expression of MAPRE3 mRNA CTD PMID:24552687 NCBI chr 5:30,972,075...31,023,447
Ensembl chr 5:30,971,985...31,023,450
JBrowse link
G Matn2 matrilin 2 increases expression ISO Rifampin results in increased expression of MATN2 mRNA CTD PMID:27177772 NCBI chr15:34,306,827...34,436,388
Ensembl chr15:34,306,823...34,436,419
JBrowse link
G Mbp myelin basic protein affects expression ISO Rifampin affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions ISO [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein CTD PMID:31629065 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA CTD PMID:21224054 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions
decreases expression
ISO Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]
Rifampin results in decreased expression of MED1 mRNA
CTD PMID:21292004 PMID:22214767 PMID:24552687 NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119
JBrowse link
G Minpp1 multiple inositol polyphosphate histidine phosphatase 1 increases expression ISO Rifampin results in increased expression of MINPP1 mRNA CTD PMID:24552687 NCBI chr19:32,463,169...32,492,770
Ensembl chr19:32,463,169...32,492,764
JBrowse link
G Mir143 microRNA 143 increases expression ISO Rifampin results in increased expression of MIR143 mRNA CTD PMID:24552687 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329
JBrowse link
G Mir145a microRNA 145a increases expression ISO Rifampin results in increased expression of MIR145 mRNA CTD PMID:24552687 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965
JBrowse link
G Mir148b microRNA 148b decreases expression ISO Rifampin results in decreased expression of MIR148B mRNA CTD PMID:24552687 NCBI chr15:103,193,552...103,193,648
Ensembl chr15:103,193,552...103,193,648
JBrowse link
G Mir149 microRNA 149 decreases expression ISO Rifampin results in decreased expression of MIR149 mRNA CTD PMID:24552687 NCBI chr 1:92,778,100...92,778,165
Ensembl chr 1:92,778,100...92,778,165
JBrowse link
G Mir15b microRNA 15b increases expression ISO Rifampin results in increased expression of MIR15B mRNA CTD PMID:24552687 NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168
JBrowse link
G Mir192 microRNA 192 decreases expression ISO Rifampin results in decreased expression of MIR192 mRNA CTD PMID:24552687 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
JBrowse link
G Mir200a microRNA 200a increases expression ISO Rifampin results in increased expression of MIR200A mRNA CTD PMID:24552687 NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442
JBrowse link
G Mir202 microRNA 202 increases expression ISO Rifampin results in increased expression of MIR202 mRNA CTD PMID:24552687 NCBI chr 7:139,537,602...139,537,673
Ensembl chr 7:139,537,602...139,537,673
JBrowse link
G Mir204 microRNA 204 increases expression ISO Rifampin results in increased expression of MIR204 mRNA CTD PMID:24552687 NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036
JBrowse link
G Mir20b microRNA 20b increases expression ISO Rifampin results in increased expression of MIR20B mRNA CTD PMID:24552687 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069
JBrowse link
G Mir212 microRNA 212 decreases expression ISO Rifampin results in decreased expression of MIR212 mRNA CTD PMID:24552687 NCBI chr11:75,064,214...75,064,304
Ensembl chr11:75,064,214...75,064,304
JBrowse link
G Mir215 microRNA 215 increases expression ISO Rifampin results in increased expression of MIR215 mRNA CTD PMID:24552687 NCBI chr 1:185,045,778...185,045,889
Ensembl chr 1:185,045,778...185,045,889
JBrowse link
G Mir21a microRNA 21a increases expression ISO Rifampin results in increased expression of MIR21 mRNA CTD PMID:24552687 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mir22 microRNA 22 increases expression ISO Rifampin results in increased expression of MIR22 mRNA CTD PMID:24552687 NCBI chr11:75,354,542...75,354,636
Ensembl chr11:75,354,542...75,354,636
JBrowse link
G Mir26b microRNA 26b increases expression ISO Rifampin results in increased expression of MIR26B mRNA CTD PMID:24552687 NCBI chr 1:74,433,469...74,433,553
Ensembl chr 1:74,433,469...74,433,553
JBrowse link
G Mir296 microRNA 296 decreases expression ISO Rifampin results in decreased expression of MIR296 mRNA CTD PMID:24552687 NCBI chr 2:174,108,840...174,108,918
Ensembl chr 2:174,108,840...174,108,918
JBrowse link
G Mir29a microRNA 29a decreases expression ISO Rifampin results in decreased expression of MIR29A mRNA CTD PMID:24552687 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682
JBrowse link
G Mir31 microRNA 31 increases expression ISO Rifampin results in increased expression of MIR31 mRNA CTD PMID:24552687 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899
JBrowse link
G Mir328 microRNA 328 increases expression ISO Rifampin results in increased expression of MIR328 mRNA CTD PMID:24552687 NCBI chr 8:106,034,996...106,035,092
Ensembl chr 8:106,034,996...106,035,092
JBrowse link
G Mir340 microRNA 340 increases expression ISO Rifampin results in increased expression of MIR340 mRNA CTD PMID:24552687 NCBI chr11:49,960,529...49,960,626
Ensembl chr11:49,960,529...49,960,626
JBrowse link
G Mir34a microRNA 34a decreases expression ISO Rifampin results in decreased expression of MIR34A mRNA CTD PMID:24552687 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012
JBrowse link
G Mir362 microRNA 362 decreases expression ISO Rifampin results in decreased expression of MIR362 mRNA CTD PMID:24552687 NCBI chr  X:7,108,221...7,108,285
Ensembl chr  X:7,108,221...7,108,285
JBrowse link
G Mir374b microRNA 374b increases expression ISO Rifampin results in increased expression of MIR374B mRNA CTD PMID:24552687 NCBI chr  X:102,616,666...102,616,760
Ensembl chr  X:102,616,666...102,616,760
JBrowse link
G Mir532 microRNA 532 decreases expression ISO Rifampin results in decreased expression of MIR532 mRNA CTD PMID:24552687 NCBI chr  X:7,114,641...7,114,736
Ensembl chr  X:7,114,641...7,114,736
JBrowse link
G Mir539 microRNA 539 increases expression ISO Rifampin results in increased expression of MIR539 mRNA CTD PMID:24552687 NCBI chr12:109,694,563...109,694,636
Ensembl chr12:109,694,563...109,694,636
JBrowse link
G Mir652 microRNA 652 decreases expression ISO Rifampin results in decreased expression of MIR652 mRNA CTD PMID:24552687 NCBI chr  X:141,521,996...141,522,093
Ensembl chr  X:141,521,996...141,522,093
JBrowse link
G Mir874 microRNA 874 decreases expression ISO Rifampin results in decreased expression of MIR874 mRNA CTD PMID:24552687 NCBI chr13:58,170,939...58,171,014
Ensembl chr13:58,170,939...58,171,014
JBrowse link
G Mirlet7e microRNA let7e increases expression ISO Rifampin results in increased expression of MIRLET7E mRNA CTD PMID:24552687 NCBI chr17:18,050,614...18,050,706
Ensembl chr17:18,050,614...18,050,706
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein CTD PMID:21224054 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases secretion ISO Rifampin results in decreased secretion of MMP3 protein CTD PMID:24890593 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:24101390 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Rifampin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr 1:155,003,620...155,022,560
Ensembl chr 1:155,003,023...155,022,560
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO Rifampin results in decreased expression of MTTP mRNA CTD PMID:32535746 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha increases expression ISO Rifampin results in increased expression of MYH6 mRNA CTD PMID:24552687 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384
JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein decreases expression ISO Rifampin results in decreased expression of NAF1 mRNA CTD PMID:24552687 NCBI chr 8:67,312,594...67,343,216
Ensembl chr 8:67,312,869...67,343,216
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 increases expression ISO Rifampin results in increased expression of NAP1L5 mRNA CTD PMID:24552687 NCBI chr 6:58,882,218...58,884,111
Ensembl chr 6:58,882,218...58,884,061
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Miconazole promotes the reaction [Rifampin results in increased expression of NCOA1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein] CTD PMID:11581012 PMID:12072427 PMID:16819505 PMID:17088262 PMID:17438109 More... NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 1:13,209,329...13,444,451
Ensembl chr 1:13,209,329...13,444,307
JBrowse link
G Ncoa6 nuclear receptor coactivator 6 multiple interactions ISO NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 2:155,232,585...155,315,741
Ensembl chr 2:155,232,576...155,315,814
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein] CTD PMID:22214767 NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein] CTD PMID:12072427 PMID:22214767 PMID:25313206 PMID:26883953 PMID:28289823 More... NCBI chr 5:125,094,217...125,256,302
Ensembl chr 5:125,094,217...125,256,283
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression
decreases activity
multiple interactions
ISO
EXP
Rifampin results in increased expression of NFE2L2 protein
Rifampin results in decreased activity of NFE2L2 protein
Rifampin inhibits the reaction [arsenite results in increased activity of NFE2L2 protein]
CTD PMID:31678598 PMID:33412187 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfya nuclear transcription factor-Y alpha decreases expression ISO Rifampin results in decreased expression of NFYA mRNA CTD PMID:24552687 NCBI chr17:48,693,917...48,716,782
Ensembl chr17:48,693,913...48,716,934
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Rifampin inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] CTD PMID:26086368 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA
Rifampin results in increased expression of NOS2 mRNA
CTD PMID:21224054 PMID:24552687 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Npas1 neuronal PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA CTD PMID:21127053 NCBI chr 7:16,189,643...16,210,741
Ensembl chr 7:16,189,646...16,211,653
JBrowse link
G Nppb natriuretic peptide type B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA CTD PMID:21127053 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression
decreases expression
ISO Rifampin results in increased expression of NR0B2 mRNA
Rifampin results in decreased expression of NR0B2 mRNA
CTD PMID:15670600 PMID:34689256 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO NR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:23732298 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of NR1H4 CTD PMID:35835356 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
decreases acetylation
affects localization
increases response to substance
increases activity
decreases response to substance
multiple interactions
increases expression
increases localization
affects binding
ISO
EXP
NR1I2 protein affects the susceptibility to Rifampin
Rifampin results in decreased acetylation of NR1I2 protein
Rifampin affects the localization of NR1I2 protein
NR1I2 protein results in increased susceptibility to Rifampin
[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein; Rifampin results in increased activity of NR1I2 protein
NR1I2 protein mutant form results in decreased susceptibility to Rifampin
1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein] which results in increased metabolism of and results in increased activity of and results in increased susceptibility to Cobicistat; [fexofenadine co-treated with Rifampin] results in increased activity of NR1I2 protein; [Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein; [Loperamide co-treated with Rifampin] results in increased activity of NR1I2 protein; [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; [NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein; [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA; [Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Camptothecin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; caraway oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Clove Oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; coriander oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Doxorubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Epirubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Fluconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; hydroxyitraconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Itraconazole promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; jasmine oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; lemongrass oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Miconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Nelfinavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]; NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased abundance of Lipids]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Oils, Volatile inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Oils, Volatile promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; oxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]; oxiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pazopanib inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin binds to and results in increased activity of NR1I2 protein; Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin inhibits the reaction [oxiconazole results in increased expression of NR1I2 mRNA]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin inhibits the reaction [trichostatin A results in increased acetylation of NR1I2 protein]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to ABCB1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]; sodium arsenite inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; trichostatin A affects the reaction [Rifampin affects the localization of NR1I2 protein]; triptolide inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
Rifampin results in increased expression of NR1I2 mRNA; Rifampin results in increased expression of NR1I2 protein
Rifampin results in increased localization of NR1I2 protein
[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; arsenite inhibits the reaction [Rifampin results in increased localization of NR1I2 protein]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]; sodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA]
Rifampin binds to NR1I2 gene mutant form
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]; Rifampin affects the localization of and results in increased activity of NR1I2 protein; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter; Rifampin binds to NR1I2 protein
CTD PMID:11581012 PMID:12065438 PMID:12072427 PMID:12370413 PMID:12417264 More... NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions
ISO
EXP
Rifampin results in increased expression of NR1I3 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein
Rifampin results in increased expression of NR1I3 mRNA; Rifampin results in increased expression of NR1I3 protein
[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 protein
CTD PMID:19118567 PMID:22733800 PMID:25835148 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression
ISO Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; NR3C1 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
Rifampin results in increased expression of NR3C1 mRNA
CTD PMID:10219967 PMID:12673034 PMID:12695351 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Nrl neural retina leucine zipper gene increases expression ISO Rifampin results in increased expression of NRL mRNA CTD PMID:24552687 NCBI chr14:55,756,973...55,762,438
Ensembl chr14:55,756,435...55,762,438
JBrowse link
G Obsl1 obscurin-like 1 decreases expression ISO Rifampin results in decreased expression of OBSL1 mRNA CTD PMID:24552687 NCBI chr 1:75,462,469...75,483,134
Ensembl chr 1:75,455,954...75,483,096
JBrowse link
G Ocln occludin affects localization EXP Rifampin affects the localization of OCLN protein CTD PMID:19577586 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Or4a47 olfactory receptor family 4 subfamily A member 47 decreases expression ISO Rifampin results in decreased expression of OR4A47 mRNA CTD PMID:24552687 NCBI chr 2:89,665,367...89,666,287
Ensembl chr 2:89,655,655...89,671,899
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide decreases expression ISO Rifampin results in decreased expression of P4HB mRNA CTD PMID:32535746 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein] CTD PMID:31678598 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pax7 paired box 7 decreases expression ISO Rifampin results in decreased expression of PAX7 mRNA CTD PMID:24552687 NCBI chr 4:139,464,357...139,560,841
Ensembl chr 4:139,464,373...139,560,839
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions
increases expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]
Rifampin results in increased expression of PCK1 mRNA
CTD PMID:24204015 PMID:34689256 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pclaf PCNA clamp associated factor increases expression ISO Rifampin results in increased expression of PCLAF mRNA CTD PMID:24552687 NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548
JBrowse link
G Pdap1 PDGFA associated protein 1 decreases expression ISO Rifampin results in decreased expression of PDAP1 mRNA CTD PMID:24552687 NCBI chr 5:145,065,580...145,076,835
Ensembl chr 5:145,065,579...145,077,048
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific decreases expression ISO Rifampin results in decreased expression of PDE4D mRNA CTD PMID:24552687 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
G Peg3 paternally expressed 3 increases expression ISO Rifampin results in increased expression of PEG3 mRNA CTD PMID:24552687 NCBI chr 7:6,706,891...6,733,443
Ensembl chr 7:6,706,891...6,733,430
JBrowse link
G Pias1 protein inhibitor of activated STAT 1 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr 9:62,785,648...62,888,161
Ensembl chr 9:62,785,650...62,895,206
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha decreases expression ISO Rifampin results in decreased expression of PILRA mRNA CTD PMID:24552687 NCBI chr 5:137,820,214...137,834,540
Ensembl chr 5:137,820,214...137,834,543
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA CTD PMID:21127053 NCBI chr 2:18,847,066...19,003,101
Ensembl chr 2:18,847,066...19,002,937
JBrowse link
G Pkd2l1 polycystic kidney disease 2-like 1 decreases expression ISO Rifampin results in decreased expression of PKD2L1 mRNA CTD PMID:24552687 NCBI chr19:44,136,076...44,235,355
Ensembl chr19:44,136,076...44,180,881
JBrowse link
G Pklr pyruvate kinase liver and red blood cell increases expression ISO Rifampin results in increased expression of PKLR mRNA CTD PMID:24552687 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
JBrowse link
G Plat plasminogen activator, tissue decreases expression ISO Rifampin results in decreased expression of PLAT mRNA CTD PMID:24552687 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO Rifampin results in increased expression of PON1 mRNA CTD PMID:26434531 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Por cytochrome p450 oxidoreductase increases activity EXP Rifampin results in increased activity of POR protein CTD PMID:12051692 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Pou2f1 POU domain, class 2, transcription factor 1 decreases expression ISO Rifampin results in decreased expression of POU2F1 mRNA CTD PMID:16837569 NCBI chr 1:165,692,719...165,830,318
Ensembl chr 1:165,692,723...165,830,247
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO
EXP
[Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA
[Isoniazid co-treated with Rifampin] results in decreased expression of PPARA protein
CTD PMID:16292757 PMID:36347327 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression
EXP [Isoniazid co-treated with Rifampin] results in decreased expression of PPARG protein; [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of PPARG mRNA; [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of PPARG mRNA alternative form; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA alternative form]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG protein]; Rifampin results in increased expression of and affects the localization of PPARG protein
Rifampin results in increased expression of PPARG mRNA
CTD PMID:27806127 PMID:33412187 PMID:36347327 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions ISO [PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [PPARGC1A protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:16857725 PMID:21292004 PMID:25069801 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A14 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA; PRKDC gene mutant form results in increased susceptibility to [Rifampin co-treated with Phenytoin co-treated with Monocrotaline] CTD PMID:21224054 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:31877331 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Prune1 prune exopolyphosphatase decreases expression ISO Rifampin results in decreased expression of PRUNE1 mRNA CTD PMID:24552687 NCBI chr 3:95,160,985...95,190,817
Ensembl chr 3:95,160,985...95,189,387
JBrowse link
G Psip1 PC4 and SFRS1 interacting protein 1 increases expression ISO Rifampin results in increased expression of PSIP1 mRNA CTD PMID:24552687 NCBI chr 4:83,373,917...83,404,700
Ensembl chr 4:83,373,917...83,404,696
JBrowse link
G Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein increases expression ISO Rifampin results in increased expression of PSMC3IP mRNA CTD PMID:24552687 NCBI chr11:100,981,238...100,986,261
Ensembl chr11:100,982,649...100,986,262
JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA CTD PMID:21224054 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B decreases expression ISO Rifampin results in decreased expression of RIC8B mRNA CTD PMID:24552687 NCBI chr10:84,753,136...84,854,201
Ensembl chr10:84,753,480...84,854,201
JBrowse link
G Rnf6 ring finger protein (C3H2C3 type) 6 decreases expression ISO Rifampin results in decreased expression of RNF6 mRNA CTD PMID:24552687 NCBI chr 5:146,146,003...146,158,267
Ensembl chr 5:146,146,002...146,158,365
JBrowse link
G Rragb Ras-related GTP binding B decreases expression ISO Rifampin results in decreased expression of RRAGB mRNA CTD PMID:24552687 NCBI chr  X:151,920,640...151,973,188
Ensembl chr  X:151,922,977...151,954,939
JBrowse link
G Rspo3 R-spondin 3 decreases expression ISO Rifampin results in decreased expression of RSPO3 mRNA CTD PMID:24552687 NCBI chr10:29,329,102...29,411,863
Ensembl chr10:29,328,412...29,411,863
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO
EXP
1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
CTD PMID:12370413 PMID:16292757 PMID:16632523 PMID:21315811 PMID:25069801 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO Rifampin results in decreased expression of SCARB1 mRNA; Rifampin results in decreased expression of SCARB1 protein CTD PMID:15883047 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 increases expression EXP Rifampin results in increased expression of SCD1 mRNA CTD PMID:27806127 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Septin8 septin 8 increases expression ISO Rifampin results in increased expression of SEPTIN8 mRNA CTD PMID:24552687 NCBI chr11:53,410,224...53,440,432
Ensembl chr11:53,410,084...53,440,392
JBrowse link
G Serpina4-ps1 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA CTD PMID:21127053 NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983
JBrowse link
G Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA CTD PMID:21127053 NCBI chr13:33,026,075...33,037,189
Ensembl chr13:33,026,075...33,035,168
JBrowse link
G Serpinb8 serine (or cysteine) peptidase inhibitor, clade B, member 8 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA CTD PMID:21127053 NCBI chr 1:107,517,668...107,536,708
Ensembl chr 1:107,517,736...107,538,214
JBrowse link
G Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 multiple interactions
increases expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA
Rifampin results in increased expression of SERPINB9 mRNA
CTD PMID:21127053 PMID:24552687 NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA
CTD PMID:21127053 PMID:21224054 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Sfxn1 sideroflexin 1 decreases expression ISO Rifampin results in decreased expression of SFXN1 mRNA CTD PMID:24552687 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions
increases expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]
Rifampin results in increased expression of SGK2 mRNA
CTD PMID:21127053 PMID:24204015 NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
JBrowse link
G Sik2 salt inducible kinase 2 decreases expression ISO Rifampin results in decreased expression of SIK2 mRNA CTD PMID:24552687 NCBI chr 9:50,800,944...50,920,432
Ensembl chr 9:50,804,101...50,920,373
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases expression
multiple interactions
ISO
EXP
Rifampin results in decreased expression of SLC10A1 mRNA
Rifampin results in decreased expression of SLC10A1 protein
[Rifampin co-treated with Isoniazid] results in decreased expression of SLC10A1 protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of SLC10A1
CTD PMID:16837569 PMID:25886055 PMID:35835356 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slc13a5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 increases expression ISO Rifampin results in increased expression of SLC13A5 mRNA; Rifampin results in increased expression of SLC13A5 protein CTD PMID:25628225 PMID:27199754 NCBI chr11:72,132,816...72,158,092
Ensembl chr11:72,132,815...72,158,048
JBrowse link
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 decreases expression ISO Rifampin results in decreased expression of SLC15A1 mRNA CTD PMID:27199754 NCBI chr14:121,697,033...121,742,666
Ensembl chr14:121,697,033...121,742,664
JBrowse link
G Slc16a12 solute carrier family 16 (monocarboxylic acid transporters), member 12 increases expression
decreases expression
ISO Rifampin results in increased expression of SLC16A12 mRNA
Rifampin results in decreased expression of SLC16A12 mRNA
CTD PMID:24552687 PMID:27199754 NCBI chr19:34,645,801...34,725,223
Ensembl chr19:34,645,803...34,724,689
JBrowse link
G Slc17a1 solute carrier family 17 (sodium phosphate), member 1 decreases expression ISO Rifampin results in decreased expression of SLC17A1 mRNA CTD PMID:27199754 NCBI chr13:24,051,607...24,079,713
Ensembl chr13:24,051,733...24,079,713
JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 decreases expression ISO Rifampin results in decreased expression of SLC1A2 mRNA CTD PMID:27199754 NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
JBrowse link
G Slc20a2 solute carrier family 20, member 2 decreases expression ISO Rifampin results in decreased expression of SLC20A2 mRNA CTD PMID:27199754 NCBI chr 8:22,966,771...23,059,632
Ensembl chr 8:22,966,804...23,059,628
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 decreases expression
multiple interactions
ISO Rifampin results in decreased expression of SLC22A1 mRNA; Rifampin results in decreased expression of SLC22A1 protein
[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]
CTD PMID:26920453 PMID:27199754 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a19 solute carrier family 22 (organic anion transporter), member 19 decreases expression ISO Rifampin results in decreased expression of SLC22A9 mRNA CTD PMID:27199754 NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 decreases expression ISO Rifampin results in decreased expression of SLC22A7 mRNA CTD PMID:16837569 PMID:27199754 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link
G Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 increases expression ISO Rifampin results in increased expression of SLC23A2 mRNA CTD PMID:27199754 NCBI chr 2:131,894,416...131,987,287
Ensembl chr 2:131,894,416...131,987,028
JBrowse link
G Slc23a3 solute carrier family 23 (nucleobase transporters), member 3 decreases expression ISO Rifampin results in decreased expression of SLC23A3 mRNA CTD PMID:27199754 NCBI chr 1:75,102,185...75,112,113
Ensembl chr 1:75,102,185...75,110,534
JBrowse link
G Slc25a22 solute carrier family 25 (mitochondrial carrier, glutamate), member 22 increases expression ISO Rifampin results in increased expression of SLC25A22 mRNA CTD PMID:27199754 NCBI chr 7:141,009,662...141,017,787
Ensembl chr 7:141,009,657...141,017,805
JBrowse link
G Slc25a34 solute carrier family 25, member 34 decreases expression ISO Rifampin results in decreased expression of SLC25A34 mRNA CTD PMID:27199754 NCBI chr 4:141,346,130...141,351,202
Ensembl chr 4:141,346,135...141,351,132
JBrowse link
G Slc25a40 solute carrier family 25, member 40 decreases expression ISO Rifampin results in decreased expression of SLC25A40 mRNA CTD PMID:24552687 NCBI chr 5:8,472,730...8,504,840
Ensembl chr 5:8,472,850...8,504,797
JBrowse link
G Slc26a2 solute carrier family 26 (sulfate transporter), member 2 decreases expression ISO Rifampin results in decreased expression of SLC26A2 mRNA CTD PMID:27199754 NCBI chr18:61,329,926...61,344,668
Ensembl chr18:61,325,991...61,344,684
JBrowse link
G Slc26a4 solute carrier family 26, member 4 decreases expression ISO Rifampin results in decreased expression of SLC26A4 mRNA CTD PMID:27199754 NCBI chr12:31,569,813...31,610,054
Ensembl chr12:31,569,826...31,609,968
JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 increases expression EXP Rifampin results in increased expression of SLC27A1 mRNA CTD PMID:27806127 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 increases expression ISO Rifampin results in increased expression of SLC27A2 mRNA CTD PMID:27199754 NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
JBrowse link
G Slc27a3 solute carrier family 27 (fatty acid transporter), member 3 decreases expression ISO Rifampin results in decreased expression of SLC27A3 mRNA CTD PMID:27199754 NCBI chr 3:90,292,540...90,298,693
Ensembl chr 3:90,292,546...90,297,245
JBrowse link
G Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 increases expression ISO Rifampin results in increased expression of SLC27A5 mRNA CTD PMID:27199754 NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119
JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 increases expression ISO Rifampin results in increased expression of SLC29A1 mRNA CTD PMID:27199754 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532
JBrowse link
G Slc29a4 solute carrier family 29 (nucleoside transporters), member 4 increases expression ISO Rifampin results in increased expression of SLC29A4 mRNA CTD PMID:27199754 NCBI chr 5:142,678,226...142,708,245
Ensembl chr 5:142,678,267...142,708,245
JBrowse link
G Slc2a12 solute carrier family 2 (facilitated glucose transporter), member 12 increases expression ISO Rifampin results in increased expression of SLC2A12 mRNA CTD PMID:27199754 NCBI chr10:22,488,821...22,579,779
Ensembl chr10:22,520,910...22,580,184
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions
decreases expression
ISO NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]
Rifampin results in decreased expression of SLC2A2 mRNA; Rifampin results in decreased expression of SLC2A2 protein
CTD PMID:26616219 PMID:27199754 PMID:34689256 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO Rifampin results in decreased expression of SLC30A10 mRNA CTD PMID:27199754 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO Rifampin results in decreased expression of SLC38A2 mRNA CTD PMID:27199754 NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611
JBrowse link
G Slc3a1 solute carrier family 3, member 1 decreases expression ISO Rifampin results in decreased expression of SLC3A1 mRNA CTD PMID:27199754 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
JBrowse link
G Slc46a3 solute carrier family 46, member 3 increases expression ISO Rifampin results in increased expression of SLC46A3 mRNA CTD PMID:27199754 NCBI chr 5:147,812,707...147,831,670
Ensembl chr 5:147,815,247...147,831,625
JBrowse link
G Slc47a1 solute carrier family 47, member 1 increases expression ISO Rifampin results in increased expression of SLC47A1 mRNA CTD PMID:27199754 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc51a solute carrier family 51, alpha subunit increases expression ISO Rifampin results in increased expression of SLC51A mRNA CTD PMID:27199754 NCBI chr16:32,294,396...32,306,697
Ensembl chr16:32,293,322...32,306,697
JBrowse link
G Slc51b solute carrier family 51, beta subunit increases expression ISO Rifampin results in increased expression of SLC51B mRNA CTD PMID:27199754 NCBI chr 9:65,320,035...65,330,055
Ensembl chr 9:65,319,996...65,330,237
JBrowse link
G Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 increases expression ISO Rifampin results in increased expression of SLC5A11 mRNA CTD PMID:27199754 NCBI chr 7:122,813,817...122,873,612
Ensembl chr 7:122,814,003...122,872,476
JBrowse link
G Slc5a12 solute carrier family 5 (sodium/glucose cotransporter), member 12 increases expression ISO Rifampin results in increased expression of SLC5A12 mRNA CTD PMID:27199754 NCBI chr 2:110,427,644...110,479,690
Ensembl chr 2:110,427,643...110,478,124
JBrowse link
G Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 increases expression ISO Rifampin results in increased expression of SLC6A12 mRNA CTD PMID:27199754 NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734
JBrowse link
G Slc6a20b solute carrier family 6 (neurotransmitter transporter), member 20B increases expression ISO Rifampin results in increased expression of SLC6A20 mRNA CTD PMID:27199754 NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630
JBrowse link
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 increases expression ISO Rifampin results in increased expression of SLC6A9 mRNA CTD PMID:27199754 NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein] CTD PMID:36878459 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 increases expression ISO Rifampin results in increased expression of SLC9A8 mRNA CTD PMID:27199754 NCBI chr 2:167,261,678...167,318,920
Ensembl chr 2:167,263,632...167,318,920
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions EXP Rifampin inhibits the reaction [SLCO1A1 protein results in increased uptake of epyrifenacil metabolite] CTD PMID:34619012 NCBI chr 6:141,853,007...141,892,688
Ensembl chr 6:141,853,008...141,892,688
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions
decreases activity
ISO
EXP
Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of Digoxin]
Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]
Rifampin results in decreased activity of SLCO1A4 protein
CTD PMID:11883641 PMID:34619012 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions
decreases activity
decreases expression
ISO
EXP
Rifampin inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of epyrifenacil metabolite]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of fexofenadine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Hydroxyurea]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Ursodeoxycholic Acid metabolite]
Rifampin inhibits the reaction [SLCO1B2 protein results in increased uptake of epyrifenacil metabolite]
Rifampin results in decreased activity of SLCO1B3 protein
Rifampin results in decreased expression of SLCO1B3 mRNA
CTD PMID:17369605 PMID:18180276 PMID:21256917 PMID:21430235 PMID:27199754 More... NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 multiple interactions
decreases activity
ISO [Rifampin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate CTD PMID:32259555 NCBI chr 6:141,470,080...141,515,903
Ensembl chr 6:141,470,094...141,515,903
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 multiple interactions ISO Rifampin inhibits the reaction [decitabine results in increased expression of SLCO2A1 mRNA] CTD PMID:23137910 NCBI chr 9:102,885,686...102,973,201
Ensembl chr 9:102,865,911...102,973,201
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions
increases expression
ISO Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]
Rifampin results in increased expression of SLCO2B1 mRNA
CTD PMID:21430235 PMID:27199754 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases expression ISO Rifampin results in increased expression of SLCO4C1 mRNA CTD PMID:27199754 NCBI chr 1:96,744,918...96,800,027
Ensembl chr 1:96,743,995...96,799,896
JBrowse link
G Smad9 SMAD family member 9 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA CTD PMID:21127053 NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678
JBrowse link
G Snca synuclein, alpha multiple interactions
increases sumoylation
ISO Rifampin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein modified form]; UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:17280646 PMID:28132806 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA CTD PMID:21127053 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Rifampin results in decreased expression of SORBS1 mRNA CTD PMID:24552687 NCBI chr19:40,280,484...40,502,399
Ensembl chr19:40,283,197...40,502,223
JBrowse link
G Sptb spectrin beta, erythrocytic increases expression ISO Rifampin results in increased expression of SPTB mRNA CTD PMID:24552687 NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Rifampin results in increased expression of SQSTM1 protein CTD PMID:29908302 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO [SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA] CTD PMID:25069801 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA CTD PMID:21127053 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Stk39 serine/threonine kinase 39 increases expression ISO Rifampin results in increased expression of STK39 mRNA CTD PMID:24552687 NCBI chr 2:68,040,789...68,302,381
Ensembl chr 2:68,040,789...68,302,612
JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 multiple interactions ISO [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer] CTD PMID:21764778 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions EXP
ISO
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter] CTD PMID:12370413 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 increases expression ISO Rifampin results in increased expression of SUMO1 protein CTD PMID:28132806 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr10:77,441,931...77,454,165
Ensembl chr10:77,441,931...77,454,165
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO Rifampin results in decreased expression of SUN1 mRNA CTD PMID:24552687 NCBI chr 5:139,186,313...139,235,594
Ensembl chr 5:139,186,392...139,235,595
JBrowse link
G Tbata thymus, brain and testes associated decreases expression ISO Rifampin results in decreased expression of TBATA mRNA CTD PMID:24552687 NCBI chr10:61,007,743...61,024,620
Ensembl chr10:61,007,733...61,024,620
JBrowse link
G Tfec transcription factor EC increases expression ISO Rifampin results in increased expression of TFEC mRNA CTD PMID:24552687 NCBI chr 6:16,830,926...16,898,463
Ensembl chr 6:16,833,372...16,898,440
JBrowse link
G Thsd4 thrombospondin, type I, domain containing 4 increases expression ISO Rifampin results in increased expression of THSD4 mRNA CTD PMID:24552687 NCBI chr 9:59,874,214...60,429,394
Ensembl chr 9:59,874,214...60,429,329
JBrowse link
G Tjp1 tight junction protein 1 affects localization
decreases expression
EXP Rifampin affects the localization of TJP1 protein
Rifampin results in decreased expression of TJP1 mRNA
CTD PMID:19577586 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tjp2 tight junction protein 2 decreases expression EXP Rifampin results in decreased expression of TJP2 mRNA CTD PMID:19577586 NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Rifampin results in increased expression of TLR1 mRNA CTD PMID:24552687 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906
JBrowse link
G Tmem120b transmembrane protein 120B decreases expression ISO Rifampin results in decreased expression of TMEM120B mRNA CTD PMID:24552687 NCBI chr 5:123,214,329...123,256,272
Ensembl chr 5:123,206,478...123,255,812
JBrowse link
G Tmem145 transmembrane protein 145 increases expression ISO Rifampin results in increased expression of TMEM145 mRNA CTD PMID:24552687 NCBI chr 7:25,004,981...25,015,621
Ensembl chr 7:25,005,531...25,015,620
JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Rifampin results in increased expression of TMEM88 mRNA CTD PMID:24552687 NCBI chr11:69,287,342...69,289,060
Ensembl chr11:69,287,345...69,289,060
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Rifampin results in decreased expression of TNF protein CTD PMID:21357946 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b multiple interactions EXP [Rifampin co-treated with Cobicistat] results in increased expression of TNFRSF10B mRNA CTD PMID:33629115 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA CTD PMID:21224054 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA CTD PMID:21224054 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
JBrowse link
G Trim43a tripartite motif-containing 43A decreases expression ISO Rifampin results in decreased expression of TRIM51 mRNA CTD PMID:24552687 NCBI chr 9:88,462,944...88,470,877
Ensembl chr 9:88,462,944...88,470,872
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression ISO Rifampin results in increased expression of TSKU mRNA CTD PMID:24552687 PMID:27177772 NCBI chr 7:97,999,875...98,010,602
Ensembl chr 7:97,999,875...98,010,535
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions ISO UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:28132806 NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856
JBrowse link
G Ugdh UDP-glucose dehydrogenase multiple interactions
increases expression
ISO [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA
Rifampin results in increased expression of UGDH mRNA
CTD PMID:16292757 NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 affects expression
increases expression
multiple interactions
ISO Rifampin affects the expression of UGT1A1 mRNA
Rifampin results in increased expression of UGT1A1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of UGT1A1 mRNA
CTD PMID:15104253 PMID:15771232 PMID:15849716 PMID:18098064 PMID:22126990 More... NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions
increases expression
ISO pimecrolimus inhibits the reaction [Rifampin results in increased expression of UGT1A3 mRNA] CTD PMID:25313206 PMID:29356861 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases expression ISO Rifampin results in increased expression of UGT1A6 mRNA CTD PMID:18094037 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases expression ISO Rifampin results in increased expression of UGT1A9 mRNA; Rifampin results in increased expression of UGT1A9 protein CTD PMID:25070100 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Uhrf2 ubiquitin-like, containing PHD and RING finger domains 2 decreases expression ISO Rifampin results in decreased expression of UHRF2 mRNA CTD PMID:24552687 NCBI chr19:30,007,920...30,071,126
Ensembl chr19:30,007,913...30,071,122
JBrowse link
G Ung uracil DNA glycosylase multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA CTD PMID:21224054 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Rifampin results in increased expression of VEGFA protein CTD PMID:25051504 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfd vascular endothelial growth factor D multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA CTD PMID:21127053 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 affects response to substance ISO VKORC1 alternative form affects the susceptibility to Rifampin CTD PMID:36789833 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 decreases expression ISO Rifampin results in decreased expression of VWA1 mRNA CTD PMID:24552687 NCBI chr 4:155,852,952...155,859,042
Ensembl chr 4:155,852,606...155,859,155
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO Rifampin results in increased expression of XIAP protein CTD PMID:12645856 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727
JBrowse link
G Zcchc13 zinc finger, CCHC domain containing 13 decreases expression ISO Rifampin results in decreased expression of ZCCHC13 mRNA CTD PMID:24552687 NCBI chr  X:102,674,187...102,675,277
Ensembl chr  X:102,674,192...102,675,276
JBrowse link
G Zfp11 zinc finger protein 11 decreases expression ISO Rifampin results in decreased expression of ZNF546 mRNA CTD PMID:24552687 NCBI chr 5:129,731,659...129,747,152
Ensembl chr 5:129,731,657...129,747,163
JBrowse link
G Zfp451 zinc finger protein 451 decreases expression ISO Rifampin results in decreased expression of ZNF451 mRNA CTD PMID:24552687 NCBI chr 1:33,800,622...33,854,683
Ensembl chr 1:33,800,626...33,853,676
JBrowse link
G Zfp46 zinc finger protein 46 decreases expression ISO Rifampin results in decreased expression of ZNF436 mRNA CTD PMID:24552687 NCBI chr 4:136,011,479...136,021,163
Ensembl chr 4:136,011,994...136,021,253
JBrowse link
G Zfp462 zinc finger protein 462 decreases expression ISO Rifampin results in decreased expression of ZNF462 mRNA CTD PMID:24552687 NCBI chr 4:54,942,038...55,083,563
Ensembl chr 4:54,945,048...55,083,563
JBrowse link
triacsin C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions ISO triacsin C inhibits the reaction [Fatty Acids results in increased degradation of ABCA1 protein]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Cholesterol]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Phospholipids]]; triacsin C inhibits the reaction [Linoleic Acid results in increased degradation of ABCA1 protein] CTD PMID:16118212 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcd3 ATP-binding cassette, sub-family D member 3 decreases expression ISO triacsin C results in decreased expression of ABCD3 mRNA CTD PMID:16704987 NCBI chr 3:121,552,553...121,609,851
Ensembl chr 3:121,552,423...121,608,951
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha multiple interactions EXP triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of ACACA protein] CTD PMID:18390901 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases activity ISO triacsin C results in decreased activity of ACSL1 protein CTD PMID:11319222 NCBI chr 8:46,924,214...46,989,088
Ensembl chr 8:46,924,074...46,989,088
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases activity ISO triacsin C results in decreased activity of ACSL4 protein CTD PMID:11319222 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 decreases expression ISO triacsin C results in decreased expression of ADARB1 mRNA CTD PMID:16704987 NCBI chr10:77,126,561...77,254,125
Ensembl chr10:77,126,560...77,254,104
JBrowse link
G Aqp3 aquaporin 3 decreases expression ISO triacsin C results in decreased expression of AQP3 mRNA CTD PMID:16704987 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO triacsin C results in increased expression of ARHGDIA mRNA CTD PMID:16704987 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO triacsin C results in increased expression of ATF3 mRNA CTD PMID:16704987 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Bdnf brain derived neurotrophic factor decreases expression ISO triacsin C results in decreased expression of BDNF mRNA CTD PMID:16704987 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Casp3 caspase 3 increases activity ISO triacsin C results in increased activity of CASP3 protein CTD PMID:16704987 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 decreases expression ISO triacsin C results in decreased expression of COL18A1 mRNA CTD PMID:16704987 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382
JBrowse link
G Ctdspl CTD small phosphatase like decreases expression ISO triacsin C results in decreased expression of CTDSPL mRNA CTD PMID:16704987 NCBI chr 9:118,751,313...118,873,187
Ensembl chr 9:118,755,521...118,873,066
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO triacsin C results in increased expression of DDIT4 mRNA CTD PMID:16704987 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Ddx24 DEAD box helicase 24 decreases expression ISO triacsin C results in decreased expression of DDX24 mRNA CTD PMID:16704987 NCBI chr12:103,374,235...103,392,106
Ensembl chr12:103,374,241...103,392,089
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO triacsin C results in decreased expression of DHCR7 mRNA CTD PMID:16704987 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Ebp EBP cholestenol delta-isomerase decreases expression ISO triacsin C results in decreased expression of EBP mRNA CTD PMID:16704987 NCBI chr  X:8,051,568...8,059,751
Ensembl chr  X:8,051,568...8,059,751
JBrowse link
G Egr1 early growth response 1 increases expression ISO triacsin C results in increased expression of EGR1 mRNA CTD PMID:16704987 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Erg28 ergosterol biosynthesis 28 decreases expression ISO triacsin C results in decreased expression of ERG28 mRNA CTD PMID:16704987 NCBI chr12:85,862,221...85,871,667
Ensembl chr12:85,862,222...85,871,324
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO triacsin C results in decreased expression of FGFR3 mRNA CTD PMID:16704987 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO triacsin C results in increased expression of FOS mRNA CTD PMID:16704987 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosl1 fos-like antigen 1 increases expression ISO triacsin C results in increased expression of FOSL1 mRNA CTD PMID:16704987 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO triacsin C results in increased expression of GCLC mRNA CTD PMID:16704987 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO triacsin C results in increased expression of GCLM mRNA CTD PMID:16704987 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO triacsin C results in decreased expression of GNPDA1 mRNA CTD PMID:16704987 NCBI chr18:38,460,588...38,472,052
Ensembl chr18:38,460,588...38,472,056
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression ISO triacsin C results in decreased expression of HMGCR mRNA CTD PMID:16704987 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO triacsin C results in increased expression of HMOX1 mRNA CTD PMID:16704987 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO triacsin C results in decreased expression of HS2ST1 mRNA CTD PMID:16704987 NCBI chr 3:144,135,462...144,275,977
Ensembl chr 3:144,135,467...144,275,942
JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO triacsin C results in decreased expression of ID3 mRNA CTD PMID:16704987 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase decreases expression ISO triacsin C results in decreased expression of IDI1 mRNA CTD PMID:16704987 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
JBrowse link
G Ift25 intraflagellar transport 25 decreases expression ISO triacsin C results in decreased expression of IFT25 mRNA CTD PMID:16704987 NCBI chr 4:107,110,889...107,137,135
Ensembl chr 4:107,110,790...107,137,135
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression ISO triacsin C results in decreased expression of IGFBP7 mRNA CTD PMID:16704987 NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888
JBrowse link
G Ilvbl ilvB (bacterial acetolactate synthase)-like decreases expression ISO triacsin C results in decreased expression of ILVBL mRNA CTD PMID:16704987 NCBI chr10:78,410,178...78,420,336
Ensembl chr10:78,410,180...78,420,336
JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain decreases expression ISO triacsin C results in decreased expression of ISL1 mRNA CTD PMID:16704987 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225
JBrowse link
G Itga6 integrin alpha 6 increases expression ISO triacsin C results in increased expression of ITGA6 mRNA CTD PMID:16704987 NCBI chr 2:71,617,236...71,688,761
Ensembl chr 2:71,575,960...71,688,760
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO triacsin C results in increased expression of and results in increased phosphorylation of JUN protein
triacsin C results in increased expression of JUN mRNA
CTD PMID:16704987 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Klf5 Kruppel-like transcription factor 5 increases expression ISO triacsin C results in increased expression of KLF5 mRNA CTD PMID:16704987 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Lss lanosterol synthase decreases expression ISO triacsin C results in decreased expression of LSS mRNA CTD PMID:16704987 NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
JBrowse link
G Luc7l3 LUC7-like 3 (S. cerevisiae) decreases expression ISO triacsin C results in decreased expression of LUC7L3 mRNA CTD PMID:16704987 NCBI chr11:94,181,899...94,213,196
Ensembl chr11:94,178,716...94,212,814
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO triacsin C results in increased expression of MAFF mRNA CTD PMID:16704987 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO triacsin C results in decreased expression of NR2F1 mRNA CTD PMID:16704987 NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO triacsin C results in decreased expression of NR4A2 mRNA CTD PMID:16704987 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nrtn neurturin decreases expression ISO triacsin C results in decreased expression of NRTN mRNA CTD PMID:16704987 NCBI chr17:57,058,323...57,064,548
Ensembl chr17:57,058,325...57,064,530
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein (myomegalin) decreases expression ISO triacsin C results in decreased expression of PDE4DIP mRNA CTD PMID:16704987 NCBI chr 3:97,597,144...97,796,023
Ensembl chr 3:97,597,140...97,796,023
JBrowse link
G Pdss2 prenyl (solanesyl) diphosphate synthase, subunit 2 decreases expression ISO triacsin C results in decreased expression of PDSS2 mRNA CTD PMID:16704987 NCBI chr10:43,095,396...43,340,878
Ensembl chr10:43,097,482...43,340,878
JBrowse link
G Phlda1 pleckstrin homology like domain, family A, member 1 increases expression ISO triacsin C results in increased expression of PHLDA1 mRNA CTD PMID:16704987 NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO triacsin C results in increased expression of PMAIP1 mRNA CTD PMID:16704987 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit multiple interactions EXP triacsin C inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of PRKAA1 protein] CTD PMID:18390901 NCBI chr15:5,172,641...5,211,380
Ensembl chr15:5,173,343...5,211,380
JBrowse link
G Prpf4 pre-mRNA processing factor 4 decreases expression ISO triacsin C results in decreased expression of PRPF4 mRNA CTD PMID:16704987 NCBI chr 4:62,327,002...62,345,227
Ensembl chr 4:62,327,034...62,345,227
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO triacsin C results in increased expression of PSAT1 mRNA CTD PMID:16704987 NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4a1 increases expression ISO triacsin C results in increased expression of PTP4A1 mRNA CTD PMID:16704987 NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 increases expression ISO triacsin C results in increased expression of RAPGEF2 mRNA CTD PMID:16704987 NCBI chr 3:78,969,818...79,194,681
Ensembl chr 3:78,969,823...79,193,824
JBrowse link
G Skp2 S-phase kinase-associated protein 2 decreases expression ISO triacsin C results in decreased expression of SKP2 mRNA CTD PMID:16704987 NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO triacsin C results in increased expression of SLC7A11 mRNA CTD PMID:16704987 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Snai2 snail family zinc finger 2 increases expression ISO triacsin C results in increased expression of SNAI2 mRNA CTD PMID:16704987 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 decreases expression ISO triacsin C results in decreased expression of SOX9 mRNA CTD PMID:16704987 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein decreases expression ISO triacsin C results in decreased expression of SPARC mRNA CTD PMID:16704987 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
JBrowse link
G Spast spastin decreases expression ISO triacsin C results in decreased expression of SPAST mRNA CTD PMID:16704987 NCBI chr17:74,643,805...74,698,110
Ensembl chr17:74,645,982...74,698,110
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO triacsin C results in increased expression of SQSTM1 mRNA CTD PMID:16704987 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 decreases expression ISO triacsin C results in decreased expression of SRGAP2 mRNA CTD PMID:16704987 NCBI chr 1:131,212,989...131,455,269
Ensembl chr 1:131,212,989...131,455,090
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO triacsin C results in increased expression of STC2 mRNA CTD PMID:16704987 NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a increases expression ISO triacsin C results in increased expression of TNFRSF12A mRNA CTD PMID:16704987 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tns3 tensin 3 decreases expression ISO triacsin C results in decreased expression of TNS3 mRNA CTD PMID:16704987 NCBI chr11:8,381,652...8,614,758
Ensembl chr11:8,381,652...8,614,681
JBrowse link
G Top2a topoisomerase (DNA) II alpha decreases expression ISO triacsin C results in decreased expression of TOP2A mRNA CTD PMID:16704987 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
G Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) increases expression EXP triacsin C results in increased expression of UCP3 mRNA CTD PMID:11056218 NCBI chr 7:100,122,198...100,135,639
Ensembl chr 7:100,122,197...100,135,639
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide increases expression ISO triacsin C results in increased expression of YWHAZ mRNA CTD PMID:16704987 NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22208
    chemical entity 22207
      atom 22200
        nonmetal atom 22085
          nitrogen atom 20031
            nitrogen molecular entity 20031
              organonitrogen compound 19838
                hydrazone 590
                  (2-adamantylideneamino)thiourea 0
                  (3E)-3-(acetamidoimino)-2-methylpropanoic acid 0
                  (E)-2-[[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]benzoic acid 0
                  1,2-di(1-phenylethylidene)hydrazine 0
                  1,3-dimethyl-6-[2-(thiophen-2-ylmethylidene)hydrazinyl]pyrimidine-2,4-dione 0
                  1-(2-furanylmethylideneamino)-3-methylthiourea 0
                  1-(butan-2-ylidene)-2-[4-(4-chlorophenyl)thiazol-2-yl]hydrazine 0
                  1-[(2-cyclohexylcyclohexylidene)amino]-3-propan-2-ylthiourea 0
                  1-[4-(4-chlorophenyl)thiazol-2-yl]-2-(pentan-3-ylidene)hydrazine 0
                  1-[4-(4-chlorophenyl)thiazol-2-yl]-2-(propan-2-ylidene)hydrazine 0
                  1-butyl-3-[(3-methyl-2-thiophenyl)methylideneamino]thiourea 0
                  1-ethyl-3-(2-furanylmethylideneamino)thiourea 0
                  1-ethyl-3-(thiophen-2-ylmethylideneamino)thiourea 0
                  2-[(E)-(acetamidoimino)methyl]pentanedioic acid 0
                  2-[2-(1-isobutylcyclohexyl)-1-methylethylidene]hydrazine-1-carboxamide 0
                  2-hydroxy-3-methoxybenzaldehyde 2-pyridylhydrazone 0
                  21-phosphorifampicin 0
                  3,5,5-trimethyl-4H-pyrazole-1-carbothioamide 0
                  3-[(2E)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-2-(phenylhydrazono)-2H-pyrrol-3-yl]propanoic acid 0
                  4EGI-1 0
                  6-methyl-2-[2-[(3-methyl-2-thiophenyl)methylidene]hydrazinyl]-1H-pyrimidin-4-one 0
                  CCCP 46
                  FPR A14 0
                  GWARJD10 0
                  NG-061 0
                  acetaldehyde hydrazone + 0
                  ambazone 0
                  bisantrene 0
                  carbonyl cyanide p-trifluoromethoxyphenylhydrazone 70
                  cyclopentylidene-[4-(4-chlorophenyl)thiazol-2-yl]hydrazone 0
                  dantrolene 54
                  dynasore 0
                  etazolate 2
                  ferimzone 0
                  gyromitrin 0
                  hydramethylnon + 2
                  hydrazonomalononitrile + 111
                  levosimendan 0
                  mitoguazone 0
                  nifurtoinol 0
                  rhosin 0
                  rifampicin + 416
                  semicarbazone + 17
                  thiosemicarbazone + 0
                  triacsin C 66
Path 2
Term Annotations click to browse term
  CHEBI ontology 22208
    subatomic particle 22200
      composite particle 22200
        hadron 22200
          baryon 22200
            nucleon 22200
              atomic nucleus 22200
                atom 22200
                  main group element atom 22134
                    main group molecular entity 22134
                      p-block molecular entity 22134
                        carbon group molecular entity 21931
                          organic molecular entity 21857
                            heteroorganic entity 21513
                              organonitrogen compound 19838
                                hydrazone 590
                                  (2-adamantylideneamino)thiourea 0
                                  (3E)-3-(acetamidoimino)-2-methylpropanoic acid 0
                                  (E)-2-[[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]benzoic acid 0
                                  1,2-di(1-phenylethylidene)hydrazine 0
                                  1,3-dimethyl-6-[2-(thiophen-2-ylmethylidene)hydrazinyl]pyrimidine-2,4-dione 0
                                  1-(2-furanylmethylideneamino)-3-methylthiourea 0
                                  1-(butan-2-ylidene)-2-[4-(4-chlorophenyl)thiazol-2-yl]hydrazine 0
                                  1-[(2-cyclohexylcyclohexylidene)amino]-3-propan-2-ylthiourea 0
                                  1-[4-(4-chlorophenyl)thiazol-2-yl]-2-(pentan-3-ylidene)hydrazine 0
                                  1-[4-(4-chlorophenyl)thiazol-2-yl]-2-(propan-2-ylidene)hydrazine 0
                                  1-butyl-3-[(3-methyl-2-thiophenyl)methylideneamino]thiourea 0
                                  1-ethyl-3-(2-furanylmethylideneamino)thiourea 0
                                  1-ethyl-3-(thiophen-2-ylmethylideneamino)thiourea 0
                                  2-[(E)-(acetamidoimino)methyl]pentanedioic acid 0
                                  2-[2-(1-isobutylcyclohexyl)-1-methylethylidene]hydrazine-1-carboxamide 0
                                  2-hydroxy-3-methoxybenzaldehyde 2-pyridylhydrazone 0
                                  21-phosphorifampicin 0
                                  3,5,5-trimethyl-4H-pyrazole-1-carbothioamide 0
                                  3-[(2E)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-2-(phenylhydrazono)-2H-pyrrol-3-yl]propanoic acid 0
                                  4EGI-1 0
                                  6-methyl-2-[2-[(3-methyl-2-thiophenyl)methylidene]hydrazinyl]-1H-pyrimidin-4-one 0
                                  CCCP 46
                                  FPR A14 0
                                  GWARJD10 0
                                  NG-061 0
                                  acetaldehyde hydrazone + 0
                                  ambazone 0
                                  bisantrene 0
                                  carbonyl cyanide p-trifluoromethoxyphenylhydrazone 70
                                  cyclopentylidene-[4-(4-chlorophenyl)thiazol-2-yl]hydrazone 0
                                  dantrolene 54
                                  dynasore 0
                                  etazolate 2
                                  ferimzone 0
                                  gyromitrin 0
                                  hydramethylnon + 2
                                  hydrazonomalononitrile + 111
                                  levosimendan 0
                                  mitoguazone 0
                                  nifurtoinol 0
                                  rhosin 0
                                  rifampicin + 416
                                  semicarbazone + 17
                                  thiosemicarbazone + 0
                                  triacsin C 66
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