Mir374b (microRNA 374b) - Rat Genome Database

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Gene: Mir374b (microRNA 374b) Mus musculus
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Symbol: Mir374b
Name: microRNA 374b
RGD ID: 1625943
MGI Page MGI
Description: Acts upstream of or within cellular response to leukemia inhibitory factor; long-term synaptic potentiation; and response to bacterium. Part of RISC complex. Is expressed in early conceptus. Orthologous to human MIR374B (microRNA 374b).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-374b; Mir374; Mirn; Mirn374; mmu-mir-3; mmu-mir-374; mmu-mir-374b
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X102,616,666 - 102,616,760 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX102,616,666 - 102,616,760 (-)EnsemblGRCm39 Ensembl
GRCm38X103,573,060 - 103,573,154 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX103,573,060 - 103,573,154 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X100,768,399 - 100,768,493 (-)NCBIGRCm37MGSCv37mm9NCBIm37
CeleraX90,474,490 - 90,474,584 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX46.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:16582102   PMID:17604727   PMID:20215419   PMID:20413612   PMID:20439489   PMID:21037258   PMID:21267068   PMID:21822254   PMID:22373575   PMID:23185045   PMID:23940725  
PMID:24205035   PMID:24838392   PMID:24899465   PMID:25071082   PMID:25858512   PMID:26107383   PMID:26498529   PMID:29902458   PMID:29917179   PMID:30565678   PMID:32908913   PMID:33479745  
PMID:35038382   PMID:35481398  


Genomics

Comparative Map Data
Mir374b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X102,616,666 - 102,616,760 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX102,616,666 - 102,616,760 (-)EnsemblGRCm39 Ensembl
GRCm38X103,573,060 - 103,573,154 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX103,573,060 - 103,573,154 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X100,768,399 - 100,768,493 (-)NCBIGRCm37MGSCv37mm9NCBIm37
CeleraX90,474,490 - 90,474,584 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX46.22NCBI
MIR374B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X74,218,547 - 74,218,618 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX74,218,547 - 74,218,618 (-)EnsemblGRCh38hg38GRCh38
GRCh37X73,438,382 - 73,438,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X73,355,106 - 73,355,177 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX73,721,851 - 73,721,922 (-)NCBICelera
Cytogenetic MapXq13.2NCBI
HuRefX67,074,208 - 67,074,279 (-)NCBIHuRef
CHM1_1X73,331,321 - 73,331,392 (-)NCBICHM1_1
T2T-CHM13v2.0X72,652,070 - 72,652,141 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in Mir374b
2 total Variants
miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:15290
Count of gene targets:6610
Count of transcripts:10385
Interacting mature miRNAs:mmu-miR-374b-3p, mmu-miR-374b-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
4141803Lmr30_mleishmaniasis resistance 30 (mouse)Not determined85062606119062720Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X80189914114190059Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
1357500Mdmsc6_mmodifier of muscularity 6 (mouse)Not determinedX75306671109306758Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000102314
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX102,616,666 - 102,616,760 (-)Ensembl
GRCm38.p6 EnsemblX103,573,060 - 103,573,154 (-)Ensembl
RefSeq Acc Id: NR_030418
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X102,616,666 - 102,616,760 (-)NCBI
GRCm38X103,573,060 - 103,573,154 (-)ENTREZGENE
MGSCv37X100,768,399 - 100,768,493 (-)RGD
CeleraX90,474,490 - 90,474,584 (-)RGD
cM MapX ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3629958 AgrOrtholog
Ensembl Genes ENSMUSG00000076269 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000102314 ENTREZGENE
MGD MGI:3629958 ENTREZGENE
miRBase MI0004125 ENTREZGENE
NCBI Gene 751546 ENTREZGENE
PhenoGen Mir374b PhenoGen
RNAcentral URS000033F45D RNACentral
  URS0000441477 RNACentral
  URS000075A533 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-27 Mir374b  microRNA 374b  Mir374  microRNA 374  Symbol and/or name change 5135510 APPROVED
2011-08-17 Mir374  microRNA 374  Mir374  microRNA 374  Symbol and/or name change 5135510 APPROVED