Gm14295 (predicted gene 14295) - Rat Genome Database

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Gene: Gm14295 (predicted gene 14295) Mus musculus
Analyze
Symbol: Gm14295
Name: predicted gene 14295
RGD ID: 2302328
MGI Page MGI
Description: Predicted to enable transcription cis-regulatory region binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: KRAB box and zinc finger, C2H2 type domain containing; novel KRAB box and zinc finger, C2H2 type domain containing protein; uncharacterized protein LOC100039123
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392176,489,972 - 176,512,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2176,490,405 - 176,505,418 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382176,798,179 - 176,814,092 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2176,798,612 - 176,811,223 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv372176,583,364 - 176,596,400 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362176,584,013 - 176,597,914 (+)NCBIMGSCv36mm8
Cytogenetic Map2H4NCBI
cM Map299.06NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14610273   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Gm14295
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392176,489,972 - 176,512,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2176,490,405 - 176,505,418 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382176,798,179 - 176,814,092 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2176,798,612 - 176,811,223 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv372176,583,364 - 176,596,400 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362176,584,013 - 176,597,914 (+)NCBIMGSCv36mm8
Cytogenetic Map2H4NCBI
cM Map299.06NCBI
ZNF840P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,490,940 - 46,492,292 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,459,441 - 46,495,558 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh372045,119,579 - 45,120,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,525,716 - 44,554,686 (+)NCBIBuild 36Build 36hg18NCBI36
Celera2041,803,725 - 41,832,694 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,860,488 - 41,861,840 (+)NCBIHuRef
CHM1_12045,022,185 - 45,023,537 (+)NCBICHM1_1
T2T-CHM13v2.02048,227,076 - 48,228,428 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in Gm14295
232 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:272
Count of miRNA genes:198
Interacting mature miRNAs:207
Transcripts:ENSMUST00000118012, ENSMUST00000132883, ENSMUST00000179435
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158078337178442452Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142593476178442452Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148238204181755017Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150212221181755017Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151778297181755017Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150212221181755017Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150212221181755017Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144515861180896594Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149236907181755017Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145228719179228841Mouse
1300676Prdt2_mprion disease incubation time 2 (mouse)Not determined2164515154181755017Mouse
1558991Tailq4_mtail length QTL 4 (mouse)Not determined2162736926178442452Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152329820181755017Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2149988902181755017Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155823920181755017Mouse
12910811Pwbwq3_mpre-weaning body weight QTL 3 (mouse)2169794802178920791Mouse
1302003Sluc17_msusceptibility to lung cancer 17 (mouse)Not determined2162433493181755017Mouse
12738409Lfibq1_mliver fibrosis QTL 1 (mouse)2167716420179207088Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145196949179197085Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1357435Epfq2_mepididymal fat pad weight QTL 2 (mouse)Not determined2162736926178442452Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156196464181755017Mouse
1301348Alcp5_malcohol preference locus 5 (mouse)Not determined2163486407181755017Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145518775179518926Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148664893181755017Mouse
1301677Alcp6_malcohol preference locus 6 (mouse)Not determined2163486407181755017Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000118012   ⟹   ENSMUSP00000113133
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2176,490,405 - 176,505,418 (+)Ensembl
GRCm38.p6 Ensembl2176,798,612 - 176,808,618 (+)Ensembl
Ensembl Acc Id: ENSMUST00000132883   ⟹   ENSMUSP00000119262
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2176,494,026 - 176,503,016 (+)Ensembl
GRCm38.p6 Ensembl2176,802,233 - 176,811,223 (+)Ensembl
Ensembl Acc Id: ENSMUST00000179435   ⟹   ENSMUSP00000136320
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2176,499,155 - 176,499,552 (+)Ensembl
GRCm38.p6 Ensembl2176,807,362 - 176,807,759 (+)Ensembl
RefSeq Acc Id: NM_001205057   ⟹   NP_001191986
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392176,490,393 - 176,500,497 (+)NCBI
GRCm382176,798,600 - 176,808,704 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030245886   ⟹   XP_030101746
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392176,489,972 - 176,512,508 (+)NCBI
GRCm382176,798,179 - 176,814,092 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030245890   ⟹   XP_030101750
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392176,489,972 - 176,512,508 (+)NCBI
GRCm382176,798,179 - 176,814,092 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001191986   ⟸   NM_001205057
- UniProtKB: A2BG90 (UniProtKB/TrEMBL),   Q8C1K5 (UniProtKB/TrEMBL),   Q8CFP2 (UniProtKB/TrEMBL),   J3QMJ8 (UniProtKB/TrEMBL),   F7CEF8 (UniProtKB/TrEMBL),   F7CEI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030101750   ⟸   XM_030245890
- Peptide Label: isoform X2
- UniProtKB: A2BG91 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030101746   ⟸   XM_030245886
- Peptide Label: isoform X1
Ensembl Acc Id: ENSMUSP00000113133   ⟸   ENSMUST00000118012
Ensembl Acc Id: ENSMUSP00000119262   ⟸   ENSMUST00000132883
Ensembl Acc Id: ENSMUSP00000136320   ⟸   ENSMUST00000179435
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A2BG91-F1-model_v2 AlphaFold A2BG91 1-834 view protein structure

Promoters
RGD ID:6879986
Promoter ID:EPDNEW_M3444
Type:multiple initiation site
Name:Gm14295_1
Description:Mus musculus predicted gene 14295 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382176,798,628 - 176,798,688EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3709624 AgrOrtholog
Ensembl Genes ENSMUSG00000078875 UniProtKB/TrEMBL
  ENSMUSG00000078877 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000095648 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000118012 ENTREZGENE
  ENSMUST00000118012.9 UniProtKB/TrEMBL
  ENSMUST00000132883 ENTREZGENE
  ENSMUST00000132883.8 UniProtKB/TrEMBL
  ENSMUST00000156844.9 UniProtKB/TrEMBL
  ENSMUST00000179349.9 UniProtKB/TrEMBL
  ENSMUST00000179435.2 UniProtKB/TrEMBL
  ENSMUST00000249361.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2-type UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:100039123 UniProtKB/TrEMBL
MGD MGI:3709624 ENTREZGENE
NCBI Gene 100039123 ENTREZGENE
PANTHER RIKEN CDNA 6720489N17 GENE-RELATED UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 544-RELATED UniProtKB/TrEMBL
  ZNF44 PROTEIN UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
  zf-H2C2_2 UniProtKB/TrEMBL
PhenoGen Gm14295 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A2BG90 ENTREZGENE, UniProtKB/TrEMBL
  A2BG91 ENTREZGENE, UniProtKB/TrEMBL
  F7CEF8 ENTREZGENE
  F7CEI1 ENTREZGENE
  J3QMJ8 ENTREZGENE, UniProtKB/TrEMBL
  Q8C1K5 ENTREZGENE, UniProtKB/TrEMBL
  Q8CFP2 ENTREZGENE, UniProtKB/TrEMBL