ZNF197 (zinc finger protein 197) - Rat Genome Database

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Gene: ZNF197 (zinc finger protein 197) Homo sapiens
Analyze
Symbol: ZNF197
Name: zinc finger protein 197
RGD ID: 1353796
HGNC Page HGNC:12988
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: D3S1363E; P18; pVHL-associated KRAB domain-containing protein; VHL-associated KRAB-A domain-containing protein; VHLaK; zinc finger protein 166; zinc finger protein 20; zinc finger protein with KRAB and SCAN domains 9; ZKSCAN9; ZNF166; ZNF20; ZSCAN41
RGD Orthologs
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38344,625,036 - 44,648,471 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl344,584,888 - 44,648,471 (+)EnsemblGRCh38hg38GRCh38
GRCh37344,666,528 - 44,689,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36344,641,515 - 44,664,967 (+)NCBINCBI36Build 36hg18NCBI36
Build 34344,645,646 - 44,661,754NCBI
Celera344,604,505 - 44,627,956 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef344,710,651 - 44,734,094 (+)NCBIHuRef
CHM1_1344,616,603 - 44,640,053 (+)NCBICHM1_1
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7814019   PMID:8353497   PMID:9380504   PMID:12477932   PMID:12682018   PMID:17043677   PMID:19274049   PMID:21873635   PMID:25277244   PMID:26186194   PMID:26496610   PMID:28514442  
PMID:30021884   PMID:33961781   PMID:35914814  


Genomics

Comparative Map Data
ZNF197
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38344,625,036 - 44,648,471 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl344,584,888 - 44,648,471 (+)EnsemblGRCh38hg38GRCh38
GRCh37344,666,528 - 44,689,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36344,641,515 - 44,664,967 (+)NCBINCBI36Build 36hg18NCBI36
Build 34344,645,646 - 44,661,754NCBI
Celera344,604,505 - 44,627,956 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef344,710,651 - 44,734,094 (+)NCBIHuRef
CHM1_1344,616,603 - 44,640,053 (+)NCBICHM1_1
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBIT2T-CHM13v2.0
ZNF197
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2244,572,043 - 44,597,902 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1344,576,985 - 44,600,567 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0344,515,051 - 44,538,475 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1345,572,800 - 45,596,127 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl345,572,803 - 45,596,127 (+)Ensemblpanpan1.1panPan2
ZNF197
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.120292,573 - 336,930 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2023,913 - 75,398 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02049,438 - 100,868 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,100 - 76,199 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.020111,876 - 163,043 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02071,173 - 122,307 (-)NCBIUU_Cfam_GSD_1.0
Znf197
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118198,619,088 - 198,657,367 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936695985,590 - 994,560 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0 EnsemblNW_004936695971,217 - 981,940 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936695947,019 - 995,013 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF197
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1327,875,490 - 27,902,191 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11327,875,474 - 27,902,193 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21330,717,363 - 30,742,036 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF197
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,096,172 - 6,122,969 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,105,911 - 6,120,667 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041161,049,709 - 161,072,848 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF197
34 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_006991.3(ZNF197):c.3021C>T (p.Ile1007=) single nucleotide variant Malignant melanoma [RCV000060830] Chr3:44644151 [GRCh38]
Chr3:44685643 [GRCh37]
Chr3:44660647 [NCBI36]
Chr3:3p21.31		 not provided
GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 copy number gain See cases [RCV000240519] Chr3:37028313..49929220 [GRCh37]
Chr3:3p22.2-21.31		 likely pathogenic
NM_006991.5(ZNF197):c.296G>A (p.Arg99Gln) single nucleotide variant Inborn genetic diseases [RCV003280275] Chr3:44629450 [GRCh38]
Chr3:44670942 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2580C>G (p.Asn860Lys) single nucleotide variant Inborn genetic diseases [RCV003288087] Chr3:44643710 [GRCh38]
Chr3:44685202 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1129A>G (p.Lys377Glu) single nucleotide variant Inborn genetic diseases [RCV003262688] Chr3:44642259 [GRCh38]
Chr3:44683751 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_006991.5(ZNF197):c.182G>A (p.Ser61Asn) single nucleotide variant Inborn genetic diseases [RCV003286301] Chr3:44629336 [GRCh38]
Chr3:44670828 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_006991.5(ZNF197):c.2758C>G (p.His920Asp) single nucleotide variant Inborn genetic diseases [RCV003261024] Chr3:44643888 [GRCh38]
Chr3:44685380 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p24.3-21.31(chr3:16923595-45249923)x2,3 copy number gain not provided [RCV000682249] Chr3:16923595..45249923 [GRCh37]
Chr3:3p24.3-21.31		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_006991.5(ZNF197):c.2128G>A (p.Glu710Lys) single nucleotide variant Inborn genetic diseases [RCV003248779] Chr3:44643258 [GRCh38]
Chr3:44684750 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.869G>T (p.Ser290Ile) single nucleotide variant Inborn genetic diseases [RCV002901066] Chr3:44641999 [GRCh38]
Chr3:44683491 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p21.31(chr3:44444902-45413927)x1 copy number loss not provided [RCV001005429] Chr3:44444902..45413927 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2482A>C (p.Ser828Arg) single nucleotide variant Inborn genetic diseases [RCV003285883] Chr3:44643612 [GRCh38]
Chr3:44685104 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.184C>T (p.Arg62Trp) single nucleotide variant Inborn genetic diseases [RCV002754729] Chr3:44629338 [GRCh38]
Chr3:44670830 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2882A>G (p.Asn961Ser) single nucleotide variant Inborn genetic diseases [RCV002729715] Chr3:44644012 [GRCh38]
Chr3:44685504 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1565A>C (p.Lys522Thr) single nucleotide variant Inborn genetic diseases [RCV002860264] Chr3:44642695 [GRCh38]
Chr3:44684187 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2305A>G (p.Arg769Gly) single nucleotide variant Inborn genetic diseases [RCV002864099] Chr3:44643435 [GRCh38]
Chr3:44684927 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2257C>T (p.Arg753Trp) single nucleotide variant Inborn genetic diseases [RCV002945483] Chr3:44643387 [GRCh38]
Chr3:44684879 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1505G>C (p.Arg502Thr) single nucleotide variant Inborn genetic diseases [RCV002839746] Chr3:44642635 [GRCh38]
Chr3:44684127 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1499A>C (p.His500Pro) single nucleotide variant Inborn genetic diseases [RCV002693681] Chr3:44642629 [GRCh38]
Chr3:44684121 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.658G>A (p.Glu220Lys) single nucleotide variant Inborn genetic diseases [RCV002987652] Chr3:44632488 [GRCh38]
Chr3:44673980 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2207G>C (p.Cys736Ser) single nucleotide variant Inborn genetic diseases [RCV002664576] Chr3:44643337 [GRCh38]
Chr3:44684829 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.62A>G (p.Asp21Gly) single nucleotide variant Inborn genetic diseases [RCV002764904] Chr3:44629216 [GRCh38]
Chr3:44670708 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1229G>A (p.Arg410His) single nucleotide variant Inborn genetic diseases [RCV002987370] Chr3:44642359 [GRCh38]
Chr3:44683851 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.902G>T (p.Cys301Phe) single nucleotide variant Inborn genetic diseases [RCV002675377] Chr3:44642032 [GRCh38]
Chr3:44683524 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1730G>A (p.Arg577Gln) single nucleotide variant Inborn genetic diseases [RCV002961731] Chr3:44642860 [GRCh38]
Chr3:44684352 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.718G>A (p.Ala240Thr) single nucleotide variant Inborn genetic diseases [RCV002807594] Chr3:44632548 [GRCh38]
Chr3:44674040 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2545A>G (p.Ser849Gly) single nucleotide variant Inborn genetic diseases [RCV002677601] Chr3:44643675 [GRCh38]
Chr3:44685167 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1702T>C (p.Cys568Arg) single nucleotide variant Inborn genetic diseases [RCV003279737] Chr3:44642832 [GRCh38]
Chr3:44684324 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1423C>T (p.Arg475Cys) single nucleotide variant Inborn genetic diseases [RCV003172934] Chr3:44642553 [GRCh38]
Chr3:44684045 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1964G>A (p.Cys655Tyr) single nucleotide variant Inborn genetic diseases [RCV003189409] Chr3:44643094 [GRCh38]
Chr3:44684586 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.673T>C (p.Cys225Arg) single nucleotide variant Inborn genetic diseases [RCV003214515] Chr3:44632503 [GRCh38]
Chr3:44673995 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.152A>G (p.His51Arg) single nucleotide variant Inborn genetic diseases [RCV003219858] Chr3:44629306 [GRCh38]
Chr3:44670798 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2540C>T (p.Ala847Val) single nucleotide variant Inborn genetic diseases [RCV003180211] Chr3:44643670 [GRCh38]
Chr3:44685162 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2480T>G (p.Phe827Cys) single nucleotide variant Inborn genetic diseases [RCV003309986] Chr3:44643610 [GRCh38]
Chr3:44685102 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.2623G>A (p.Glu875Lys) single nucleotide variant Inborn genetic diseases [RCV003372321] Chr3:44643753 [GRCh38]
Chr3:44685245 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.3050A>G (p.Gln1017Arg) single nucleotide variant Inborn genetic diseases [RCV003373168] Chr3:44644180 [GRCh38]
Chr3:44685672 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_006991.5(ZNF197):c.1137T>G (p.Phe379Leu) single nucleotide variant Inborn genetic diseases [RCV003367832] Chr3:44642267 [GRCh38]
Chr3:44683759 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p21.31(chr3:44563378-45177006)x3 copy number gain not provided [RCV003484127] Chr3:44563378..45177006 [GRCh37]
Chr3:3p21.31		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2107
Count of miRNA genes:897
Interacting mature miRNAs:1048
Transcripts:ENST00000334075, ENST00000344387, ENST00000383744, ENST00000383745, ENST00000396058, ENST00000412641
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-35297  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37344,685,693 - 44,685,912UniSTSGRCh37
Build 36344,660,697 - 44,660,916RGDNCBI36
Celera344,623,686 - 44,623,905RGD
Cytogenetic Map3p21UniSTS
HuRef344,729,824 - 44,730,043UniSTS
TNG Radiation Hybrid Map328057.0UniSTS
GeneMap99-GB4 RH Map3144.91UniSTS
Whitehead-RH Map3168.9UniSTS
NCBI RH Map3433.1UniSTS
GeneMap99-G3 RH Map31836.0UniSTS
RH71310  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37344,683,521 - 44,683,683UniSTSGRCh37
Build 36344,658,525 - 44,658,687RGDNCBI36
Celera344,621,514 - 44,621,676RGD
Cytogenetic Map3p21UniSTS
HuRef344,727,652 - 44,727,814UniSTS
GeneMap99-GB4 RH Map3148.34UniSTS
NCBI RH Map3412.7UniSTS
STS-L32163  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37344,685,575 - 44,685,696UniSTSGRCh37
Build 36344,660,579 - 44,660,700RGDNCBI36
Celera344,623,568 - 44,623,689RGD
Cytogenetic Map3p21UniSTS
HuRef344,729,706 - 44,729,827UniSTS
GeneMap99-GB4 RH Map3144.91UniSTS
SHGC-76875  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37344,689,718 - 44,689,864UniSTSGRCh37
Build 36344,664,722 - 44,664,868RGDNCBI36
Celera344,627,711 - 44,627,857RGD
Cytogenetic Map3p21UniSTS
Cytogenetic Map3p21.32UniSTS
HuRef344,733,849 - 44,733,995UniSTS
TNG Radiation Hybrid Map328062.0UniSTS
GeneMap99-GB4 RH Map3143.05UniSTS
D3S1363  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3p21UniSTS
L18441  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q31UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map9p13.3-p12UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic Map2q33-q34UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map1p32UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map2p13UniSTS
Cytogenetic MapXq12UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map10q11.2UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map13q12.3UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map1p31UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map15q24-q25UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map16q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 89 51 375 16 474 18 393 45 423 46 307 452 1 10 144 1
Low 2350 2741 1350 607 1289 446 3963 2132 3309 372 1152 1161 174 1 1194 2644 4 2
Below cutoff 199 1 1 185 1 20 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001024855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001323293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001323294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001323295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001323296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_136582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF011573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK314196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL117657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY074878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY261677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY279353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC017584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ002665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT584382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z21707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000334075   ⟹   ENSP00000334616
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl344,625,095 - 44,647,778 (+)Ensembl
RefSeq Acc Id: ENST00000344387   ⟹   ENSP00000345809
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl344,625,036 - 44,648,471 (+)Ensembl
RefSeq Acc Id: ENST00000383744   ⟹   ENSP00000373250
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl344,625,019 - 44,647,504 (+)Ensembl
RefSeq Acc Id: ENST00000383745   ⟹   ENSP00000373251
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl344,625,049 - 44,648,471 (+)Ensembl
RefSeq Acc Id: ENST00000396058   ⟹   ENSP00000379370
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl344,628,988 - 44,645,262 (+)Ensembl
RefSeq Acc Id: ENST00000412641   ⟹   ENSP00000394713
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl344,584,888 - 44,629,390 (+)Ensembl
RefSeq Acc Id: NM_001024855   ⟹   NP_001020026
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
GRCh37344,666,511 - 44,689,963 (+)RGD
GRCh37344,666,511 - 44,689,963 (+)NCBI
Build 36344,641,515 - 44,664,967 (+)NCBI Archive
Celera344,604,505 - 44,627,956 (+)RGD
HuRef344,710,651 - 44,734,094 (+)ENTREZGENE
CHM1_1344,616,603 - 44,640,053 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001323293   ⟹   NP_001310222
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001323294   ⟹   NP_001310223
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001323295   ⟹   NP_001310224
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001323296   ⟹   NP_001310225
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006991   ⟹   NP_008922
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
GRCh37344,666,511 - 44,689,963 (+)RGD
Build 36344,641,515 - 44,661,758 (+)NCBI Archive
Celera344,604,505 - 44,627,956 (+)RGD
HuRef344,710,651 - 44,734,094 (+)ENTREZGENE
CHM1_1344,616,603 - 44,636,844 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
RefSeq Acc Id: NR_136582
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,648,471 (+)NCBI
T2T-CHM13v2.0344,640,750 - 44,664,179 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001020026   ⟸   NM_001024855
- Peptide Label: isoform 2
- UniProtKB: O14709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_008922   ⟸   NM_006991
- Peptide Label: isoform 1
- UniProtKB: B2RAH8 (UniProtKB/Swiss-Prot),   Q86VG0 (UniProtKB/Swiss-Prot),   O14709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001310222   ⟸   NM_001323293
- Peptide Label: isoform 1
- UniProtKB: B2RAH8 (UniProtKB/Swiss-Prot),   Q86VG0 (UniProtKB/Swiss-Prot),   O14709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001310224   ⟸   NM_001323295
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: NP_001310223   ⟸   NM_001323294
- Peptide Label: isoform 2
- UniProtKB: O14709 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001310225   ⟸   NM_001323296
- Peptide Label: isoform 4
- Sequence:
RefSeq Acc Id: ENSP00000334616   ⟸   ENST00000334075
RefSeq Acc Id: ENSP00000394713   ⟸   ENST00000412641
RefSeq Acc Id: ENSP00000379370   ⟸   ENST00000396058
RefSeq Acc Id: ENSP00000345809   ⟸   ENST00000344387
RefSeq Acc Id: ENSP00000373250   ⟸   ENST00000383744
RefSeq Acc Id: ENSP00000373251   ⟸   ENST00000383745
Protein Domains
C2H2-type   KRAB   SCAN box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O14709-F1-model_v2 AlphaFold O14709 1-1029 view protein structure

Promoters
RGD ID:6864128
Promoter ID:EPDNEW_H5229
Type:initiation region
Name:ZNF197_1
Description:zinc finger protein 197
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H5228  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38344,625,036 - 44,625,096EPDNEW
RGD ID:6801998
Promoter ID:HG_KWN:44677
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000344387,   NM_001024855,   OTTHUMT00000343835,   UC003CNO.1,   UC003CNP.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36344,641,436 - 44,642,087 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
COSMIC ZNF197 COSMIC
Ensembl Genes ENSG00000186448 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000281709 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000334075.6 UniProtKB/TrEMBL
  ENST00000344387 ENTREZGENE
  ENST00000344387.9 UniProtKB/Swiss-Prot
  ENST00000383744 ENTREZGENE
  ENST00000383744.8 UniProtKB/Swiss-Prot
  ENST00000383745 ENTREZGENE
  ENST00000383745.6 UniProtKB/Swiss-Prot
  ENST00000396058 ENTREZGENE
  ENST00000396058.1 UniProtKB/Swiss-Prot
  ENST00000412641.1 UniProtKB/TrEMBL
  ENST00000627004 UniProtKB/TrEMBL
  ENST00000627517.2 UniProtKB/Swiss-Prot
  ENST00000627752.2 UniProtKB/Swiss-Prot
  ENST00000627845.1 UniProtKB/Swiss-Prot
  ENST00000627858 UniProtKB/TrEMBL
  ENST00000628172.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.4020.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000186448 GTEx
  ENSG00000281709 GTEx
HGNC ID HGNC:12988 ENTREZGENE
Human Proteome Map ZNF197 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10168 UniProtKB/Swiss-Prot
NCBI Gene 10168 ENTREZGENE
OMIM 618359 OMIM
PANTHER GASTRULA ZINC FINGER PROTEIN XLCGF26.1-LIKE-RELATED UniProtKB/Swiss-Prot
  PROTEIN ZBED8-RELATED UniProtKB/TrEMBL
  SCAN DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/Swiss-Prot
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA37568 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN_BOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SCAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP Retrovirus capsid dimerization domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RAH8 ENTREZGENE
  C9JQH5_HUMAN UniProtKB/TrEMBL
  F8WEU5_HUMAN UniProtKB/TrEMBL
  O14709 ENTREZGENE
  Q4G1C8_HUMAN UniProtKB/TrEMBL
  Q7Z6G1_HUMAN UniProtKB/TrEMBL
  Q86VG0 ENTREZGENE
  ZN197_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B2RAH8 UniProtKB/Swiss-Prot
  Q86VG0 UniProtKB/Swiss-Prot