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Gene: ZNF197 (zinc finger protein 197) Homo sapiens
Symbol: ZNF197
Name: zinc finger protein 197
Description: This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Naturally-occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID:110354863. [provided by RefSeq, May 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D3S1363E; P18; pVHL-associated KRAB domain-containing protein; VHL-associated KRAB-A domain-containing protein; VHLaK; zinc finger protein 166; zinc finger protein 20; zinc finger protein with KRAB and SCAN domains 9; ZKSCAN9; ZNF166; ZNF20; ZSCAN41
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF197 (zinc finger protein 197)
Canis lupus familiaris (dog) : LOC491421 (zinc finger protein 197)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Znf197 (zinc finger protein 197)
Sus scrofa (pig) : ZNF197 (zinc finger protein 197)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38344,625,036 - 44,648,471 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37344,666,511 - 44,689,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36344,641,515 - 44,664,967 (+)NCBINCBI36hg18NCBI36
Build 34344,645,646 - 44,661,754NCBI
Celera344,604,505 - 44,627,956 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef344,710,651 - 44,734,094 (+)NCBIHuRef
CHM1_1344,616,603 - 44,640,053 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ZNF197
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353796
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.