ZNF534 (zinc finger protein 534) - Rat Genome Database

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Gene: ZNF534 (zinc finger protein 534) Homo sapiens
Analyze
Symbol: ZNF534
Name: zinc finger protein 534
RGD ID: 1604994
HGNC Page HGNC:26337
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of PcG protein complex and transcription regulator complex. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FLJ25344; KRAB domain only 3; KRAB domain only protein 3; KRBO3
RGD Orthologs
Bonobo
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381952,429,148 - 52,452,263 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1952,429,148 - 52,452,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371952,932,401 - 52,955,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361957,626,485 - 57,634,511 (+)NCBINCBI36Build 36hg18NCBI36
Celera1949,984,739 - 49,992,765 (+)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1949,265,050 - 49,273,076 (+)NCBIHuRef
CHM1_11952,936,479 - 52,944,505 (+)NCBICHM1_1
T2T-CHM13v2.01955,513,831 - 55,536,813 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21873635   PMID:32296183  


Genomics

Comparative Map Data
ZNF534
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381952,429,148 - 52,452,263 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1952,429,148 - 52,452,315 (+)EnsemblGRCh38hg38GRCh38
GRCh371952,932,401 - 52,955,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361957,626,485 - 57,634,511 (+)NCBINCBI36Build 36hg18NCBI36
Celera1949,984,739 - 49,992,765 (+)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1949,265,050 - 49,273,076 (+)NCBIHuRef
CHM1_11952,936,479 - 52,944,505 (+)NCBICHM1_1
T2T-CHM13v2.01955,513,831 - 55,536,813 (+)NCBIT2T-CHM13v2.0
ZNF534
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22058,478,793 - 58,495,334 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11960,403,238 - 60,419,776 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01949,382,312 - 49,393,070 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ZNF534
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1645,201,650 - 45,208,617 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607325,264,316 - 25,273,255 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in ZNF534
32 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3 copy number gain See cases [RCV000050883] Chr19:50191219..58535818 [GRCh38]
Chr19:50694476..59047185 [GRCh37]
Chr19:55386288..63738997 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3 copy number gain See cases [RCV000052926] Chr19:51141518..58539965 [GRCh38]
Chr19:51644775..59051332 [GRCh37]
Chr19:56336587..63743144 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
NM_001143938.1(ZNF534):c.568G>A (p.Glu190Lys) single nucleotide variant Malignant melanoma [RCV000072308] Chr19:52438028 [GRCh38]
Chr19:52941281 [GRCh37]
Chr19:57633093 [NCBI36]
Chr19:19q13.41		 not provided
NM_001143938.1(ZNF534):c.874C>T (p.His292Tyr) single nucleotide variant Malignant melanoma [RCV000072309] Chr19:52438334 [GRCh38]
Chr19:52941587 [GRCh37]
Chr19:57633399 [NCBI36]
Chr19:19q13.41		 not provided
NM_001143938.1(ZNF534):c.1019C>T (p.Ser340Phe) single nucleotide variant Malignant melanoma [RCV000072310] Chr19:52438479 [GRCh38]
Chr19:52941732 [GRCh37]
Chr19:57633544 [NCBI36]
Chr19:19q13.41		 not provided
NM_001143938.1(ZNF534):c.1203G>A (p.Arg401=) single nucleotide variant Malignant melanoma [RCV000072311] Chr19:52438663 [GRCh38]
Chr19:52941916 [GRCh37]
Chr19:57633728 [NCBI36]
Chr19:19q13.41		 not provided
NM_001143938.1(ZNF534):c.1706G>A (p.Arg569Lys) single nucleotide variant Malignant melanoma [RCV000072312] Chr19:52439166 [GRCh38]
Chr19:52942419 [GRCh37]
Chr19:57634231 [NCBI36]
Chr19:19q13.41		 not provided
NM_001143938.3(ZNF534):c.13C>A (p.Gln5Lys) single nucleotide variant Malignant tumor of prostate [RCV000149066] Chr19:52431487 [GRCh38]
Chr19:52934740 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3 copy number gain See cases [RCV000135843] Chr19:50152520..58581203 [GRCh38]
Chr19:50655777..59092570 [GRCh37]
Chr19:55347589..63784382 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:52143873-58445521)x3 copy number gain See cases [RCV000142008] Chr19:52143873..58445521 [GRCh38]
Chr19:52647126..58956888 [GRCh37]
Chr19:57338938..63648700 [NCBI36]
Chr19:19q13.41-13.43		 pathogenic
NM_001291368.1(ZNF534):c.272-1534C>T single nucleotide variant Lung cancer [RCV000101309] Chr19:52449653 [GRCh38]
Chr19:52952906 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.41(chr19:52825019-53017595)x1 copy number loss See cases [RCV000240580] Chr19:52825019..53017595 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3 copy number gain See cases [RCV000445925] Chr19:50489390..59095359 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_001143938.3(ZNF534):c.649A>G (p.Ser217Gly) single nucleotide variant Inborn genetic diseases [RCV003299117] Chr19:52438109 [GRCh38]
Chr19:52941362 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
NM_001143938.3(ZNF534):c.1475A>C (p.Lys492Thr) single nucleotide variant Inborn genetic diseases [RCV003287592] Chr19:52438935 [GRCh38]
Chr19:52942188 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
NM_001143938.3(ZNF534):c.56A>C (p.Gln19Pro) single nucleotide variant Inborn genetic diseases [RCV003291526] Chr19:52433995 [GRCh38]
Chr19:52937248 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3 copy number gain not provided [RCV000740208] Chr19:50740074..59097160 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42		 not provided
NM_001143938.3(ZNF534):c.1511G>A (p.Arg504His) single nucleotide variant Inborn genetic diseases [RCV003242691] Chr19:52438971 [GRCh38]
Chr19:52942224 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438) copy number gain not specified [RCV002052689] Chr19:49911081..53127438 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
NM_001143938.3(ZNF534):c.1697C>T (p.Ala566Val) single nucleotide variant Inborn genetic diseases [RCV002753753] Chr19:52439157 [GRCh38]
Chr19:52942410 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.37G>A (p.Val13Met) single nucleotide variant Inborn genetic diseases [RCV002732404] Chr19:52433976 [GRCh38]
Chr19:52937229 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1961G>A (p.Ser654Asn) single nucleotide variant Inborn genetic diseases [RCV002682678] Chr19:52439421 [GRCh38]
Chr19:52942674 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.806C>G (p.Pro269Arg) single nucleotide variant Inborn genetic diseases [RCV002868216] Chr19:52438266 [GRCh38]
Chr19:52941519 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.239A>G (p.Asp80Gly) single nucleotide variant Inborn genetic diseases [RCV002660226] Chr19:52435177 [GRCh38]
Chr19:52938430 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.142G>C (p.Gly48Arg) single nucleotide variant Inborn genetic diseases [RCV002868390] Chr19:52434081 [GRCh38]
Chr19:52937334 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.310T>C (p.Ser104Pro) single nucleotide variant Inborn genetic diseases [RCV002661107] Chr19:52437770 [GRCh38]
Chr19:52941023 [GRCh37]
Chr19:19q13.41		 likely benign
NM_001143938.3(ZNF534):c.1316A>G (p.Glu439Gly) single nucleotide variant Inborn genetic diseases [RCV002889080] Chr19:52438776 [GRCh38]
Chr19:52942029 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.907T>C (p.Cys303Arg) single nucleotide variant Inborn genetic diseases [RCV002699288] Chr19:52438367 [GRCh38]
Chr19:52941620 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.553C>G (p.Pro185Ala) single nucleotide variant Inborn genetic diseases [RCV002697474] Chr19:52438013 [GRCh38]
Chr19:52941266 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.565A>C (p.Asn189His) single nucleotide variant Inborn genetic diseases [RCV002956034] Chr19:52438025 [GRCh38]
Chr19:52941278 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1648T>C (p.Tyr550His) single nucleotide variant Inborn genetic diseases [RCV002964218] Chr19:52439108 [GRCh38]
Chr19:52942361 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1159T>A (p.Cys387Ser) single nucleotide variant Inborn genetic diseases [RCV002672780] Chr19:52438619 [GRCh38]
Chr19:52941872 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.142+15C>A single nucleotide variant Inborn genetic diseases [RCV003214945] Chr19:52434096 [GRCh38]
Chr19:52937349 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.342G>T (p.Gln114His) single nucleotide variant Inborn genetic diseases [RCV003209775] Chr19:52437802 [GRCh38]
Chr19:52941055 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1721G>A (p.Gly574Glu) single nucleotide variant Inborn genetic diseases [RCV003212172] Chr19:52439181 [GRCh38]
Chr19:52942434 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1898C>T (p.Pro633Leu) single nucleotide variant Inborn genetic diseases [RCV003261248] Chr19:52439358 [GRCh38]
Chr19:52942611 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1846A>C (p.Ser616Arg) single nucleotide variant Inborn genetic diseases [RCV003341348] Chr19:52439306 [GRCh38]
Chr19:52942559 [GRCh37]
Chr19:19q13.41		 uncertain significance
NM_001143938.3(ZNF534):c.1438A>G (p.Asn480Asp) single nucleotide variant Inborn genetic diseases [RCV003357641] Chr19:52438898 [GRCh38]
Chr19:52942151 [GRCh37]
Chr19:19q13.41		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
NM_001143938.3(ZNF534):c.1698G>A (p.Ala566=) single nucleotide variant not provided [RCV003415402] Chr19:52439158 [GRCh38]
Chr19:52942411 [GRCh37]
Chr19:19q13.41		 likely benign
NM_001143938.3(ZNF534):c.1497T>C (p.Cys499=) single nucleotide variant not provided [RCV003425400] Chr19:52438957 [GRCh38]
Chr19:52942210 [GRCh37]
Chr19:19q13.41		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:940
Count of miRNA genes:449
Interacting mature miRNAs:484
Transcripts:ENST00000301085, ENST00000332323, ENST00000432303, ENST00000433050
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1 1 1 1
Low 177 119 110 9 79 9 666 132 2305 29 544 134 1 97 545
Below cutoff 1948 2297 1249 318 987 175 3335 1949 1353 214 709 1249 146 1061 2134 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000301085   ⟹   ENSP00000301085
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1952,429,187 - 52,452,315 (+)Ensembl
RefSeq Acc Id: ENST00000332323   ⟹   ENSP00000327538
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1952,431,414 - 52,439,446 (+)Ensembl
RefSeq Acc Id: ENST00000432303   ⟹   ENSP00000409421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1952,431,414 - 52,451,939 (+)Ensembl
RefSeq Acc Id: ENST00000433050   ⟹   ENSP00000391358
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1952,429,148 - 52,442,499 (+)Ensembl
RefSeq Acc Id: ENST00000617900   ⟹   ENSP00000480956
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1952,431,414 - 52,451,939 (+)Ensembl
RefSeq Acc Id: NM_001143938   ⟹   NP_001137410
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381952,429,148 - 52,442,499 (+)NCBI
GRCh371952,932,394 - 52,942,720 (+)NCBI
Celera1949,984,739 - 49,992,765 (+)RGD
HuRef1949,265,050 - 49,273,076 (+)ENTREZGENE
CHM1_11952,936,479 - 52,944,505 (+)NCBI
T2T-CHM13v2.01955,513,831 - 55,527,158 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001143939   ⟹   NP_001137411
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381952,429,148 - 52,442,499 (+)NCBI
GRCh371952,932,394 - 52,942,720 (+)NCBI
Celera1949,984,739 - 49,992,765 (+)RGD
HuRef1949,265,050 - 49,273,076 (+)ENTREZGENE
CHM1_11952,936,479 - 52,944,505 (+)NCBI
T2T-CHM13v2.01955,513,831 - 55,527,158 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291368   ⟹   NP_001278297
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381952,429,148 - 52,452,263 (+)NCBI
CHM1_11952,936,479 - 52,956,879 (+)NCBI
T2T-CHM13v2.01955,513,831 - 55,536,813 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291369   ⟹   NP_001278298
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381952,429,148 - 52,452,263 (+)NCBI
CHM1_11952,936,479 - 52,956,879 (+)NCBI
T2T-CHM13v2.01955,513,831 - 55,536,813 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001351679   ⟹   NP_001338608
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381952,429,148 - 52,442,499 (+)NCBI
T2T-CHM13v2.01955,513,831 - 55,527,158 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001137410   ⟸   NM_001143938
- Peptide Label: isoform 1
- UniProtKB: Q76KX8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001137411   ⟸   NM_001143939
- Peptide Label: isoform 2
- UniProtKB: Q76KX9 (UniProtKB/Swiss-Prot),   Q76KX8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001278297   ⟸   NM_001291368
- Peptide Label: isoform 3
- UniProtKB: Q1T7F5 (UniProtKB/TrEMBL),   Q96LN7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278298   ⟸   NM_001291369
- Peptide Label: isoform 4
- UniProtKB: Q1T7F6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001338608   ⟸   NM_001351679
- Peptide Label: isoform 5
- Sequence:
RefSeq Acc Id: ENSP00000327538   ⟸   ENST00000332323
RefSeq Acc Id: ENSP00000409421   ⟸   ENST00000432303
RefSeq Acc Id: ENSP00000480956   ⟸   ENST00000617900
RefSeq Acc Id: ENSP00000391358   ⟸   ENST00000433050
RefSeq Acc Id: ENSP00000301085   ⟸   ENST00000301085
Protein Domains
KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q76KX8-F1-model_v2 AlphaFold Q76KX8 1-674 view protein structure

Promoters
RGD ID:13205473
Promoter ID:EPDNEW_H26317
Type:initiation region
Name:ZNF534_1
Description:zinc finger protein 534
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381952,429,148 - 52,429,208EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:26337 AgrOrtholog
COSMIC ZNF534 COSMIC
Ensembl Genes ENSG00000198633 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000301085 ENTREZGENE
  ENST00000301085.8 UniProtKB/TrEMBL
  ENST00000332323 ENTREZGENE
  ENST00000332323.10 UniProtKB/Swiss-Prot
  ENST00000432303 ENTREZGENE
  ENST00000432303.6 UniProtKB/TrEMBL
  ENST00000433050 ENTREZGENE
  ENST00000433050.6 UniProtKB/Swiss-Prot
  ENST00000617900.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/Swiss-Prot
GTEx ENSG00000198633 GTEx
HGNC ID HGNC:26337 ENTREZGENE
Human Proteome Map ZNF534 Human Proteome Map
InterPro KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report hsa:147658 UniProtKB/Swiss-Prot
NCBI Gene 147658 ENTREZGENE
PANTHER GENE 12845-RELATED UniProtKB/Swiss-Prot
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED UniProtKB/TrEMBL
  TRANSCRIPTIONAL REPRESSOR PROTEIN YY UniProtKB/Swiss-Prot
Pfam KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/Swiss-Prot
PharmGKB PA134911920 PharmGKB
PROSITE KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
SMART KRAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57667 UniProtKB/Swiss-Prot
UniProt Q1T7F5 ENTREZGENE, UniProtKB/TrEMBL
  Q1T7F6 ENTREZGENE, UniProtKB/TrEMBL
  Q76KX8 ENTREZGENE
  Q76KX9 ENTREZGENE
  Q96LN7 ENTREZGENE, UniProtKB/TrEMBL
  ZN534_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q76KX9 UniProtKB/Swiss-Prot