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Gene: ZNF175 (zinc finger protein 175) Homo sapiens

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Symbol:

ZNF175

Name:

zinc finger protein 175

RGD ID:

1346277

HGNC Page

HGNC:12964

Description:

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleolus.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

OTK18; zinc finger protein OTK18

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	51,571,283 - 51,592,510 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	51,571,283 - 51,592,510 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	52,074,536 - 52,095,763 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	56,766,343 - 56,784,803 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	56,766,342 - 56,784,802	NCBI
Celera	19	49,125,591 - 49,144,051 (+)	NCBI		Celera
Cytogenetic Map	19	q13.41	NCBI
HuRef	19	48,406,861 - 48,425,367 (+)	NCBI		HuRef
CHM1_1	19	52,076,460 - 52,094,902 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	54,659,955 - 54,681,159 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF175	Human	arsane	multiple interactions	EXP		6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ZNF175 more ...	CTD	PMID:39836092
ZNF175	Human	arsenic atom	multiple interactions	EXP		6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ZNF175 more ...	CTD	PMID:39836092
ZNF175	Human	atrazine	decreases expression	EXP		6480464	Atrazine results in decreased expression of ZNF175 mRNA	CTD	PMID:22378314
ZNF175	Human	bisphenol A	decreases expression	ISO	RGD:7510716	6480464	bisphenol A results in decreased expression of ZNF175 mRNA	CTD	PMID:25181051
ZNF175	Human	CU-O LINKAGE	increases expression	EXP		6480464	cupric oxide results in increased expression of ZNF175 mRNA	CTD	PMID:22077320
ZNF175	Human	Dibutyl phosphate	affects expression	EXP		6480464	di-n-butylphosphoric acid affects the expression of ZNF175 mRNA	CTD	PMID:37042841
ZNF175	Human	doxorubicin	affects expression	EXP		6480464	Doxorubicin affects the expression of ZNF175 mRNA	CTD	PMID:29803840
ZNF175	Human	ethyl methanesulfonate	increases expression	EXP		6480464	Ethyl Methanesulfonate results in increased expression of ZNF175 mRNA	CTD	PMID:23649840
ZNF175	Human	GSK-J4	decreases expression	EXP		6480464	GSK-J4 results in decreased expression of ZNF175 mRNA	CTD	PMID:29301935
ZNF175	Human	lead(0)	decreases expression	EXP		6480464	Lead results in decreased expression of ZNF175 mRNA	CTD	PMID:37386098
ZNF175	Human	manganese atom	multiple interactions	EXP		6480464	[manganese chloride results in increased abundance of Manganese] which results in increased expression of ZNF175 more ...	CTD	PMID:39836092
ZNF175	Human	manganese(0)	multiple interactions	EXP		6480464	[manganese chloride results in increased abundance of Manganese] which results in increased expression of ZNF175 more ...	CTD	PMID:39836092
ZNF175	Human	manganese(II) chloride	multiple interactions	EXP		6480464	[manganese chloride results in increased abundance of Manganese] which results in increased expression of ZNF175 more ...	CTD	PMID:39836092
ZNF175	Human	methotrexate	affects response to substance	EXP		6480464	ZNF175 protein affects the susceptibility to Methotrexate	CTD	PMID:16217747
ZNF175	Human	methyl methanesulfonate	increases expression	EXP		6480464	Methyl Methanesulfonate results in increased expression of ZNF175 mRNA	CTD	PMID:23649840
ZNF175	Human	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of ZNF175 mRNA	CTD	PMID:26690555
ZNF175	Human	sodium arsenite	multiple interactions	EXP		6480464	[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of ZNF175 more ...	CTD	PMID:39836092
ZNF175	Human	sunitinib	increases expression	EXP		6480464	Sunitinib results in increased expression of ZNF175 mRNA	CTD	PMID:31533062
ZNF175	Human	temozolomide	decreases expression	EXP		6480464	Temozolomide results in decreased expression of ZNF175 mRNA	CTD	PMID:31758290
ZNF175	Human	triphenyl phosphate	affects expression	EXP		6480464	triphenyl phosphate affects the expression of ZNF175 mRNA	CTD	PMID:37042841
ZNF175	Human	urethane	increases expression	EXP		6480464	Urethane results in increased expression of ZNF175 mRNA	CTD	PMID:28818685
ZNF175	Human	valproic acid	decreases expression	EXP		6480464	Valproic Acid results in decreased expression of ZNF175 mRNA	CTD	PMID:23179753\|PMID:28001369
ZNF175	Human	vorinostat	decreases expression	EXP		6480464	vorinostat results in decreased expression of ZNF175 mRNA	CTD	PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF175	Human	defense response to virus	involved_in	IEA	UniProtKB-KW:KW-0051	150520179		UniProt	GO_REF:0000043
ZNF175	Human	negative regulation of transcription by RNA polymerase II	involved_in	IDA		150520179	PMID:17170456	NTNU_SB	PMID:17170456
ZNF175	Human	positive regulation of transcription by RNA polymerase II	involved_in	IDA		150520179	PMID:17170456	NTNU_SB	PMID:17170456
ZNF175	Human	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR001909\|InterPro:IPR036051	150520179		InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF175	Human	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
ZNF175	Human	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
ZNF175	Human	cytosol	located_in	IDA		150520179		HPA	GO_REF:0000052
ZNF175	Human	nucleolus	located_in	IDA		150520179		HPA	GO_REF:0000052
ZNF175	Human	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044
ZNF175	Human	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF175	Human	DNA binding	enables	IEA	UniProtKB-KW:KW-0238	150520179		UniProt	GO_REF:0000043
ZNF175	Human	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	IDA		150520179	PMID:17170456	NTNU_SB	PMID:17170456
ZNF175	Human	DNA-binding transcription factor activity	enables	TAS		150520179	PMID:8838321	PINC	PMID:8838321
ZNF175	Human	DNA-binding transcription repressor activity, RNA polymerase II-specific	enables	IDA		150520179	PMID:17170456	NTNU_SB	PMID:17170456
ZNF175	Human	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
ZNF175	Human	protein binding	enables	IPI	UniProtKB:O43586\|UniProtKB:P13196\|UniProtKB:P15622-3\|UniProtKB:P60409\|UniProtKB:Q14C61	150520179	PMID:25416956	IntAct	PMID:25416956
ZNF175	Human	protein binding	enables	IPI	UniProtKB:O43296\|UniProtKB:P13196	150520179	PMID:32296183	IntAct	PMID:32296183
ZNF175	Human	RNA polymerase II transcription regulatory region sequence-specific DNA binding	enables	IDA		150520179	PMID:17170456	NTNU_SB	PMID:17170456
ZNF175	Human	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	150520179		UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:1602151	PMID:8838321	PMID:12477932	PMID:12574502	PMID:14688346	PMID:15057824	PMID:15081264	PMID:15489334	PMID:17170456	PMID:18029348	PMID:18773297	PMID:18776638
PMID:19034669	PMID:19034670	PMID:19247725	PMID:19274049	PMID:20211142	PMID:20379614	PMID:20936779	PMID:21873635	PMID:21988832	PMID:22491018	PMID:25416956	PMID:29987050
PMID:32296183	PMID:33637726	PMID:33660365	PMID:33961781	PMID:34048709	PMID:34644545	PMID:38334954

ZNF175
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	51,571,283 - 51,592,510 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	51,571,283 - 51,592,510 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	52,074,536 - 52,095,763 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	56,766,343 - 56,784,803 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	56,766,342 - 56,784,802	NCBI
Celera	19	49,125,591 - 49,144,051 (+)	NCBI		Celera
Cytogenetic Map	19	q13.41	NCBI
HuRef	19	48,406,861 - 48,425,367 (+)	NCBI		HuRef
CHM1_1	19	52,076,460 - 52,094,902 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	54,659,955 - 54,681,159 (+)	NCBI		T2T-CHM13v2.0

Zfp719
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	103,146,519 - 103,159,466 (+)	NCBI		GRCr8
mRatBN7.2	1	94,009,957 - 94,027,342 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	93,992,492 - 94,023,023 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	99,500,211 - 99,513,269 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	99,505,677 - 99,512,489 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
RGSC_v3.4	1	93,986,011 - 93,992,829 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	88,285,533 - 88,298,523 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

ZNF175
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	57,615,288 - 57,634,195 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	59,539,778 - 59,558,470 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	48,516,303 - 48,534,799 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	57,398,056 - 57,416,654 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	57,400,149 - 57,416,487 (+)	Ensembl	panpan1.1		panPan2

ZNF175
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	105,502,656 - 105,522,206 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	105,504,293 - 105,519,911 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	105,077,271 - 105,095,186 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	106,013,880 - 106,031,791 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	106,012,005 - 106,029,202 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	105,685,871 - 105,703,796 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	105,327,179 - 105,345,108 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	106,122,004 - 106,139,929 (-)	NCBI		UU_Cfam_GSD_1.0

Znf175
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	4,864,624 - 4,875,954 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004937026	30,049 - 37,338 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004937026	24,788 - 35,657 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZNF175
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	58,408,885 - 58,419,435 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	58,407,424 - 58,419,481 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,770,506 - 51,782,972 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZNF175
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	44,409,441 - 44,423,508 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	44,410,243 - 44,423,378 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	24,463,687 - 24,479,485 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in ZNF175
59 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:50191219-58535818)x3	copy number gain	See cases [RCV000050883]	Chr19:50191219..58535818 [GRCh38] Chr19:50694476..59047185 [GRCh37] Chr19:55386288..63738997 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3	copy number gain	See cases [RCV000052925]	Chr19:49907832..58557889 [GRCh38] Chr19:50411089..59069256 [GRCh37] Chr19:55102901..63761068 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.41-13.43(chr19:51141518-58539965)x3	copy number gain	See cases [RCV000052926]	Chr19:51141518..58539965 [GRCh38] Chr19:51644775..59051332 [GRCh37] Chr19:56336587..63743144 [NCBI36] Chr19:19q13.41-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3	copy number gain	See cases [RCV000052914]	Chr19:47908540..58539965 [GRCh38] Chr19:48411797..59051332 [GRCh37] Chr19:53103609..63743144 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3	copy number gain	See cases [RCV000052915]	Chr19:47929575..58572206 [GRCh38] Chr19:48432832..59083573 [GRCh37] Chr19:53124644..63775385 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:50152520-58581203)x3	copy number gain	See cases [RCV000135843]	Chr19:50152520..58581203 [GRCh38] Chr19:50655777..59092570 [GRCh37] Chr19:55347589..63784382 [NCBI36] Chr19:19q13.33-13.43	pathogenic
GRCh38/hg38 19q13.41(chr19:51202361-51993020)x3	copy number gain	See cases [RCV000143450]	Chr19:51202361..51993020 [GRCh38] Chr19:51705617..52496273 [GRCh37] Chr19:56397429..57188085 [NCBI36] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:50489390-59095359)x3	copy number gain	See cases [RCV000445925]	Chr19:50489390..59095359 [GRCh37] Chr19:19q13.33-13.43	pathogenic
NM_007147.4(ZNF175):c.1460A>G (p.Lys487Arg)	single nucleotide variant	not specified [RCV004293322]	Chr19:51587791 [GRCh38] Chr19:52091044 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3	copy number gain	See cases [RCV000511289]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic\|uncertain significance
NM_007147.4(ZNF175):c.100G>A (p.Val34Met)	single nucleotide variant	not specified [RCV004297924]	Chr19:51581418 [GRCh38] Chr19:52084671 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.1467G>C (p.Gln489His)	single nucleotide variant	not specified [RCV004304750]	Chr19:51587798 [GRCh38] Chr19:52091051 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)	copy number gain	See cases [RCV000512296]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3	copy number gain	not provided [RCV000752444]	Chr19:260912..59097160 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3	copy number gain	not provided [RCV000752439]	Chr19:68029..59110290 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19q13.33-13.43(chr19:50740074-59097160)x3	copy number gain	not provided [RCV000740208]	Chr19:50740074..59097160 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3	copy number gain	not provided [RCV001007050]	Chr19:44738088..53621561 [GRCh37] Chr19:19q13.31-13.42	pathogenic
NM_007147.4(ZNF175):c.638G>T (p.Gly213Val)	single nucleotide variant	not specified [RCV004322781]	Chr19:51586969 [GRCh38] Chr19:52090222 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871)	copy number gain	not provided [RCV001249294]	Chr19:47939842..54626871 [GRCh37] Chr19:19q13.32-13.42	not provided
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3	copy number gain	not provided [RCV001259944]	Chr19:48463931..57095254 [GRCh37] Chr19:19q13.33-13.43	pathogenic
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438)	copy number gain	not specified [RCV002052689]	Chr19:49911081..53127438 [GRCh37] Chr19:19q13.33-13.41	likely pathogenic
GRCh37/hg19 19q13.41(chr19:51769834-52415762)x3	copy number gain	not provided [RCV001827892]	Chr19:51769834..52415762 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1574A>T (p.His525Leu)	single nucleotide variant	not specified [RCV004307962]	Chr19:51587905 [GRCh38] Chr19:52091158 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1904G>T (p.Arg635Ile)	single nucleotide variant	not specified [RCV004122512]	Chr19:51588235 [GRCh38] Chr19:52091488 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1363G>A (p.Ala455Thr)	single nucleotide variant	not specified [RCV004085977]	Chr19:51587694 [GRCh38] Chr19:52090947 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.2045A>G (p.Asn682Ser)	single nucleotide variant	not specified [RCV004134130]	Chr19:51588376 [GRCh38] Chr19:52091629 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.158G>A (p.Arg53Gln)	single nucleotide variant	not specified [RCV004137818]	Chr19:51581476 [GRCh38] Chr19:52084729 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.676G>T (p.Val226Phe)	single nucleotide variant	not specified [RCV004147876]	Chr19:51587007 [GRCh38] Chr19:52090260 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1747G>A (p.Gly583Ser)	single nucleotide variant	not specified [RCV004116663]	Chr19:51588078 [GRCh38] Chr19:52091331 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1400G>T (p.Arg467Ile)	single nucleotide variant	not specified [RCV004180201]	Chr19:51587731 [GRCh38] Chr19:52090984 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1615G>A (p.Ala539Thr)	single nucleotide variant	not specified [RCV004205762]	Chr19:51587946 [GRCh38] Chr19:52091199 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.193G>T (p.Ala65Ser)	single nucleotide variant	not specified [RCV004184250]	Chr19:51581511 [GRCh38] Chr19:52084764 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.1027G>T (p.Val343Phe)	single nucleotide variant	not specified [RCV004214674]	Chr19:51587358 [GRCh38] Chr19:52090611 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1125G>A (p.Met375Ile)	single nucleotide variant	not specified [RCV004132998]	Chr19:51587456 [GRCh38] Chr19:52090709 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.70G>A (p.Glu24Lys)	single nucleotide variant	not specified [RCV004173536]	Chr19:51573399 [GRCh38] Chr19:52076652 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.802A>G (p.Lys268Glu)	single nucleotide variant	not specified [RCV004165823]	Chr19:51587133 [GRCh38] Chr19:52090386 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.284A>G (p.Gln95Arg)	single nucleotide variant	not specified [RCV004236756]	Chr19:51581871 [GRCh38] Chr19:52085124 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1760A>G (p.Tyr587Cys)	single nucleotide variant	not specified [RCV004097909]	Chr19:51588091 [GRCh38] Chr19:52091344 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1918G>A (p.Glu640Lys)	single nucleotide variant	not specified [RCV004191022]	Chr19:51588249 [GRCh38] Chr19:52091502 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.680T>C (p.Val227Ala)	single nucleotide variant	not specified [RCV004175453]	Chr19:51587011 [GRCh38] Chr19:52090264 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1309C>T (p.His437Tyr)	single nucleotide variant	not specified [RCV004176388]	Chr19:51587640 [GRCh38] Chr19:52090893 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.653A>G (p.Asn218Ser)	single nucleotide variant	not specified [RCV004238471]	Chr19:51586984 [GRCh38] Chr19:52090237 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.544A>G (p.Ile182Val)	single nucleotide variant	not specified [RCV004274032]	Chr19:51586875 [GRCh38] Chr19:52090128 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1103G>A (p.Cys368Tyr)	single nucleotide variant	not specified [RCV004276161]	Chr19:51587434 [GRCh38] Chr19:52090687 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.36G>C (p.Gln12His)	single nucleotide variant	not specified [RCV004267969]	Chr19:51573365 [GRCh38] Chr19:52076618 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.767A>G (p.Gln256Arg)	single nucleotide variant	not specified [RCV004253782]	Chr19:51587098 [GRCh38] Chr19:52090351 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1745C>G (p.Thr582Arg)	single nucleotide variant	not specified [RCV004319040]	Chr19:51588076 [GRCh38] Chr19:52091329 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1988G>A (p.Arg663Gln)	single nucleotide variant	not specified [RCV004309574]	Chr19:51588319 [GRCh38] Chr19:52091572 [GRCh37] Chr19:19q13.41	uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3	copy number gain	not provided [RCV003485200]	Chr19:49625130..57647352 [GRCh37] Chr19:19q13.33-13.43	likely pathogenic
NM_007147.4(ZNF175):c.1351G>A (p.Glu451Lys)	single nucleotide variant	not specified [RCV004491553]	Chr19:51587682 [GRCh38] Chr19:52090935 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.158G>C (p.Arg53Pro)	single nucleotide variant	not specified [RCV004491554]	Chr19:51581476 [GRCh38] Chr19:52084729 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1670A>C (p.Lys557Thr)	single nucleotide variant	not specified [RCV004491556]	Chr19:51588001 [GRCh38] Chr19:52091254 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.676G>A (p.Val226Ile)	single nucleotide variant	not specified [RCV004491561]	Chr19:51587007 [GRCh38] Chr19:52090260 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.781T>C (p.Cys261Arg)	single nucleotide variant	not specified [RCV004491562]	Chr19:51587112 [GRCh38] Chr19:52090365 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1975A>G (p.Lys659Glu)	single nucleotide variant	not specified [RCV004491558]	Chr19:51588306 [GRCh38] Chr19:52091559 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.2065C>T (p.His689Tyr)	single nucleotide variant	not specified [RCV004491560]	Chr19:51588396 [GRCh38] Chr19:52091649 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.851G>A (p.Cys284Tyr)	single nucleotide variant	not specified [RCV004491563]	Chr19:51587182 [GRCh38] Chr19:52090435 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1652G>A (p.Arg551Lys)	single nucleotide variant	not specified [RCV004491555]	Chr19:51587983 [GRCh38] Chr19:52091236 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.203A>T (p.Tyr68Phe)	single nucleotide variant	not specified [RCV004491559]	Chr19:51581790 [GRCh38] Chr19:52085043 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.709T>C (p.Ser237Pro)	single nucleotide variant	not specified [RCV004687556]	Chr19:51587040 [GRCh38] Chr19:52090293 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1289A>G (p.Gln430Arg)	single nucleotide variant	not specified [RCV004687559]	Chr19:51587620 [GRCh38] Chr19:52090873 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1274G>C (p.Gly425Ala)	single nucleotide variant	not specified [RCV004688058]	Chr19:51587605 [GRCh38] Chr19:52090858 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.2054A>G (p.Asn685Ser)	single nucleotide variant	not specified [RCV004687555]	Chr19:51588385 [GRCh38] Chr19:52091638 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1382A>G (p.His461Arg)	single nucleotide variant	not specified [RCV004687557]	Chr19:51587713 [GRCh38] Chr19:52090966 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.994G>T (p.Asp332Tyr)	single nucleotide variant	not specified [RCV004687553]	Chr19:51587325 [GRCh38] Chr19:52090578 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.431G>A (p.Arg144His)	single nucleotide variant	not specified [RCV004688057]	Chr19:51586762 [GRCh38] Chr19:52090015 [GRCh37] Chr19:19q13.41	likely benign
NM_007147.4(ZNF175):c.383A>G (p.Asp128Gly)	single nucleotide variant	not specified [RCV004687558]	Chr19:51586714 [GRCh38] Chr19:52089967 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.853G>T (p.Gly285Trp)	single nucleotide variant	not specified [RCV004687554]	Chr19:51587184 [GRCh38] Chr19:52090437 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.749C>T (p.Thr250Ile)	single nucleotide variant	not specified [RCV004886110]	Chr19:51587080 [GRCh38] Chr19:52090333 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1277A>T (p.Lys426Ile)	single nucleotide variant	not specified [RCV004886113]	Chr19:51587608 [GRCh38] Chr19:52090861 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1355G>A (p.Cys452Tyr)	single nucleotide variant	not specified [RCV004886109]	Chr19:51587686 [GRCh38] Chr19:52090939 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.557C>T (p.Pro186Leu)	single nucleotide variant	not specified [RCV004886115]	Chr19:51586888 [GRCh38] Chr19:52090141 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.363G>T (p.Met121Ile)	single nucleotide variant	not specified [RCV004886119]	Chr19:51586694 [GRCh38] Chr19:52089947 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.301G>A (p.Glu101Lys)	single nucleotide variant	not specified [RCV004886111]	Chr19:51586632 [GRCh38] Chr19:52089885 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.679G>T (p.Val227Phe)	single nucleotide variant	not specified [RCV004886112]	Chr19:51587010 [GRCh38] Chr19:52090263 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.789T>G (p.His263Gln)	single nucleotide variant	not specified [RCV004886114]	Chr19:51587120 [GRCh38] Chr19:52090373 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.1390G>T (p.Val464Phe)	single nucleotide variant	not specified [RCV004886116]	Chr19:51587721 [GRCh38] Chr19:52090974 [GRCh37] Chr19:19q13.41	uncertain significance
NM_007147.4(ZNF175):c.101T>C (p.Val34Ala)	single nucleotide variant	not specified [RCV004886118]	Chr19:51581419 [GRCh38] Chr19:52084672 [GRCh37] Chr19:19q13.41	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	956
Count of miRNA genes:	645
Interacting mature miRNAs:	704
Transcripts:	ENST00000262259, ENST00000436511, ENST00000545217, ENST00000596504, ENST00000600460
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1559110	SCL22_H	Serum cholesterol level QTL 22 (human)	3.59	0.000241	Lipid level	LDL cholesterol	19	31907594	57907594	Human
1331657	COPD9_H	Chronic obstructive pulmonary disease QTL 9 (human)	1.94		Chronic airflow obstruction	post-bronchodilator FEV1	19	31021760	57021760	Human
406957534	GWAS606510_H	response to xenobiotic stimulus QTL GWAS606510 (human)		0.0000003	response to xenobiotic stimulus		19	51581583	51581584	Human

G31547

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	52,077,039 - 52,077,153	UniSTS	GRCh37
Build 36	19	56,768,851 - 56,768,965	RGD	NCBI36
Celera	19	49,128,099 - 49,128,213	RGD
Cytogenetic Map	19	q13.4	UniSTS
HuRef	19	48,409,369 - 48,409,483	UniSTS

SHGC-110678

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	52,076,263 - 52,076,380	UniSTS	GRCh37
Build 36	19	56,768,075 - 56,768,192	RGD	NCBI36
Celera	19	49,127,323 - 49,127,440	RGD
Cytogenetic Map	19	q13.4	UniSTS
HuRef	19	48,408,593 - 48,408,710	UniSTS
TNG Radiation Hybrid Map	19	21903.0	UniSTS

RH12308

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	52,092,709 - 52,092,896	UniSTS	GRCh37
Build 36	19	56,784,521 - 56,784,708	RGD	NCBI36
Celera	19	49,143,769 - 49,143,956	RGD
Cytogenetic Map	19	q13.33	UniSTS
Cytogenetic Map	19	q13.4	UniSTS
HuRef	19	48,425,085 - 48,425,272	UniSTS
GeneMap99-GB4 RH Map	19	275.75	UniSTS
NCBI RH Map	19	562.5	UniSTS

SHGC-32377

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	52,088,284 - 52,088,433	UniSTS	GRCh37
Build 36	19	56,780,096 - 56,780,245	RGD	NCBI36
Celera	19	49,139,344 - 49,139,493	RGD
Cytogenetic Map	19	q13.4	UniSTS
HuRef	19	48,420,660 - 48,420,809	UniSTS
TNG Radiation Hybrid Map	19	21894.0	UniSTS

ZNF175__4968

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	19	52,092,142 - 52,093,004	UniSTS	GRCh37
Build 36	19	56,783,954 - 56,784,816	RGD	NCBI36
Celera	19	49,143,202 - 49,144,064	RGD
HuRef	19	48,424,518 - 48,425,380	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2438	2788	2253	4974	1725	2349	5	623	1951	464	2270	7303	6471	53	3734	1	852	1744	1616	174	1


RefSeq Transcripts	NM_007147	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_136208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017027249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC018755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC020914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AI221738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK292687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AW500087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC052997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX474148	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471135	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CQ840917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D50419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DB528741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FB353527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000262259 ⟹ ENSP00000262259

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	51,571,283 - 51,592,510 (+)	Ensembl

Ensembl Acc Id:

ENST00000436511 ⟹ ENSP00000440578

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	51,573,328 - 51,589,738 (+)	Ensembl

Ensembl Acc Id:

ENST00000545217 ⟹ ENSP00000444424

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	51,571,298 - 51,574,210 (+)	Ensembl

Ensembl Acc Id:

ENST00000596504 ⟹ ENSP00000470922

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	51,571,304 - 51,581,546 (+)	Ensembl

Ensembl Acc Id:

ENST00000600460

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	51,581,368 - 51,587,362 (+)	Ensembl

RefSeq Acc Id:

NM_007147 ⟹ NP_009078

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	51,571,283 - 51,592,510 (+)	NCBI
GRCh37	19	52,074,531 - 52,092,991 (+)	ENTREZGENE
Build 36	19	56,766,343 - 56,784,803 (+)	NCBI Archive
HuRef	19	48,406,861 - 48,425,367 (+)	ENTREZGENE
CHM1_1	19	52,076,419 - 52,094,902 (+)	NCBI
T2T-CHM13v2.0	19	54,659,955 - 54,681,159 (+)	NCBI

Sequence:

show sequence

GACCATTTAGCTTCTGTTGTTAAGTGGATCTAAGCCTATGTCGCTTACTGGACGCTGAAGTGATTGGGAATATTAGCAGTGGGGGTTCTGTAGGGTCAGGAAGGGGCGGCTGGCTTTGGGGGAGTGAT
GAGGGGCTTGTTGGGGGTGGGGGTGCGTGATAAAGGGATTTCTCGGCTGAAGACGAGGCTGTGAGGCTTCTGCAGAACCCCCAGGTCAGGCCACATCATTGAGGCTGCAGGATCTCTCTTCATAGCCC
AGTACGACTCTCCGCCGTGTCCCTGGTTGGAAAATCCAAACACCTATCCAGCTTCTGGCTCCTGGGAAAAGTGGAGTTGTCAGCAAGAGAGACCGAGAGTAGAAGCCCAGAGTGGAGATGCCTGCTGA
TGTGAATTTATCCCAGAAGCCTCAGGTCCTGGGTCCAGAGAAGCAGGATGGATCTTGCGAGGCATCAGTGTCATTTGAGGACGTGACCGTGGACTTCAGCAGGGAGGAGTGGCAGCAACTGGACCCTG
CCCAGAGATGCCTGTACCGGGATGTGATGCTGGAGCTCTATAGCCATCTCTTCGCAGTGGGGTATCACATTCCCAACCCAGAGGTCATCTTCAGAATGCTAAAAGAAAAGGAGCCGCGTGTGGAGGAG
GCTGAAGTCTCACATCAGAGGTGTCAAGAAAGGGAGTTTGGGCTTGAAATCCCACAAAAGGAGATTTCTAAGAAAGCTTCATTTCAAAAGGATATGGTAGGTGAGTTCACAAGAGATGGTTCATGGTG
TTCCATTTTAGAAGAACTGAGGCTGGATGCTGACCGCACAAAGAAAGATGAGCAAAATCAAATTCAACCCATGAGTCACAGTGCTTTCTTCAACAAGAAAACATTGAACACAGAAAGCAATTGTGAAT
ATAAGGACCCTGGGAAAATGATTCGCACGAGGCCCCACCTTGCTTCTTCACAGAAACAACCTCAGAAATGTTGCTTATTTACAGAAAGTTTGAAGCTGAACCTAGAAGTGAACGGTCAGAATGAAAGC
AATGACACAGAACAGCTTGATGACGTTGTTGGGTCTGGTCAGCTATTCAGCCATAGCTCTTCTGATGCCTGCAGCAAGAATATTCATACAGGAGAGACATTTTGCAAAGGTAACCAGTGTAGAAAAGT
CTGTGGCCATAAACAGTCACTCAAGCAACATCAAATTCATACTCAGAAGAAACCAGATGGATGTTCTGAATGTGGGGGGAGCTTCACCCAGAAGTCACACCTCTTTGCCCAACAGAGAATTCATAGTG
TAGGAAACCTCCATGAATGTGGCAAATGTGGAAAAGCCTTCATGCCACAACTAAAACTCAGTGTATATCTGACAGATCATACAGGTGATATACCCTGTATATGCAAGGAATGTGGGAAGGTCTTTATT
CAGAGATCAGAATTGCTTACGCACCAGAAAACACACACTAGAAAGAAGCCCTATAAATGCCATGACTGTGGAAAAGCCTTTTTCCAGATGTTATCTCTCTTCAGACATCAGAGAACTCACAGTAGAGA
AAAACTCTATGAATGCAGTGAATGTGGCAAAGGCTTCTCCCAAAACTCAACCCTCATTATACATCAGAAAATTCATACTGGTGAGAGACAGTATGCATGCAGTGAATGTGGGAAAGCCTTTACCCAGA
AGTCAACACTCAGCTTGCACCAGAGAATCCACTCAGGGCAGAAGTCCTATGTGTGTATCGAATGCGGGCAGGCCTTCATCCAGAAGGCACACCTGATTGTCCATCAAAGAAGCCACACAGGAGAAAAA
CCTTATCAGTGCCACAACTGTGGGAAATCCTTCATTTCCAAGTCACAGCTTGATATACATCATCGAATTCATACAGGGGAGAAACCTTATGAATGCAGTGACTGTGGAAAAACCTTCACCCAAAAGTC
ACACCTGAATATACACCAGAAAATTCATACTGGAGAAAGACACCATGTATGCAGTGAATGCGGGAAAGCCTTCAACCAGAAGTCAATACTCAGCATGCATCAGAGAATTCACACCGGAGAGAAGCCTT
ACAAATGCAGTGAATGTGGGAAAGCCTTCACTTCTAAGTCTCAATTCAAAGAGCATCAGCGAATTCACACGGGTGAGAAACCCTATGTGTGCACTGAATGTGGGAAGGCCTTCAACGGCAGGTCAAAT
TTCCATAAACATCAAATAACTCACACTAGAGAGAGGCCTTTTGTCTGTTACAAATGTGGGAAGGCTTTTGTCCAGAAATCAGAGTTGATTACCCATCAAAGAACTCACATGGGAGAGAAACCCTATGA
ATGCCTTGACTGTGGGAAATCGTTCAGTAAGAAACCACAACTCAAGGTGCATCAGCGAATTCACACGGGAGAAAGACCTTATGTGTGTTCTGAATGTGGAAAGGCCTTCAACAACAGGTCAAACTTCA
ATAAACACCAAACAACTCATACCAGAGACAAATCTTACAAATGCAGTTATTCTGTGAAAGGCTTTACCAAGCAATGAATTCCTAGTGCATCAGCATATTCATAAATGAAATATACTCCGAGTTTCTTG
AAGAAGAGAAAATCTTCTCAGAATCAGGTCTAATTATATGTTATTGAATTCATGCTTCAGAAAAACTCTAGGGATGCACTGCATGTGTGAACACATGATAAAAAAGTCATGCTTTATTTTAGTGAGGG
CAATTACAGAGAAAAGAGTAAGCAGAAATGTCCTTCTGAGTACTGGCCTCATTAAGGATTATAAATTTTCTCCCCGGGAAGAAACCCTGACTAACGCATTGAGAAAAGCCTTTCTGTAAAGAATGGTA
CAAGACAGGTTGTTACTCGATTATTTATAGTAAAATATGTGGGAAATTATATCAATGATAACCCTGTTTATTGTGGGATATCAATATTTTTAAAGTGCCAACACAGTCATGATAGGACAATATTTTAT
GTGTGTGTGTGCGCCTTATGTATATAAGCATATATATAATATATAAGCATATTATTATATACAGGTTGAGTATCCCTTCTCCAAAATGCCTGGGATCAGAAGCATTTTGGATTTCAGATACTTACAGA
TTTTGGAATATTTGCATTATATTTATTGGTTGAGCATCCCTAATCTGAAAATCCAAGATTAAATGCTCCAATTAGCATTTCCTTTGAGCGTCATGTTAGAGTTCAAAAAGTTTCAGATTTTGGGTTTT
CAGATTAGGAATACCCAACCTGTATGTACGTATATTTCTGTATCTATGTATGTATATATATGCATATGCAGACATATGTATATGGTCTGGTCAGCATATGTGTATGTATGCGTATGTATGTATGTATG
TATGCCCTCAGTGCAGTGGGGTTTGCTGCAGAATTCACTGCATAGCAGGAGATGTAAGCAGATGAGTTATTTTTTAAGAGAATCTAATCTAATTGTTTTTATAAAAATTATTCCCTATTGAATATTTA
TATAATGAGGTTGTATCAACAATGATTAACTCCTTTATTATACATACACATGAATGTGCATTTTTGGTAAATGCATAAATGAGATTCTATAATGTTTACTGATCTTTATATTACAGATTTTCTCTTCT
TTTAGGATTAGCTCAGCTTGCCCCCCCTTTCCATCTCCACCATCTATAGTGAGCCTCTCCATAATTAGTGCCAACCATTAGTCTCGTTCATATTTTTACACCAGGAGTCAACAAACTGTGGCCATTGG
CCAAATATGGCCTCCCAACTGTTTTTTTAAAATAAAGTTTTATTGGAACACAGCCATGTTCATTTGGACATGTATTGTCTGGGCTTCTTTTGTGCTGCACTGGCAGAATTGAGTAGTTTTGGCGGAGA
TCAAATAGCCCCCAAGCTGGAAACTGAAAATATCTACTCTCTGGCTCTTTACAGAAAATGTTTGCCAGCACATGATACACACACAAACACACACACATACACACATATTACTATGTTCATCATCATAT
ACCTGTGTAAGTACTCTTTCATTGATTTATAAAACTCAGATCTCTTACGTGTGTGGATGGTATTTTTTTCATTCTACAATCCATGATGGATTGTACACACGTGTATTCTATGAGGTTGACCTGCCATA
ATTTATTTAGCCATTCCCACAGTTTTGATTACTTATTTCCTCCCCACACACATTTTTTGCTAAAAAACGGAGAGGGAACTGTTATCAATACTTCCGAGAAGCAGACCAGCATAATCTTTTAAGTGCAC
AGGCCCAGGAGCCAGGTTCCTGCATTTGATTCCTGGCTCCACTCTCTACCCTCTGCATCTGCTGAGCAAGTTATTTGGTCTCATCTATTCTGGTTTTCTCATCTACAAAAGGGAGATGATGATAGTAC
CCTACCCCCATGCATTTGGTGTGAGAAGTGTGTGTGTGTTAAACCCTTGGAACTGCATGGACAGACCAAGTGCTGATGAATTTTAGCGGGCCTCGTATCCCTGAGCCTGCCTGGTTCCCTTGTGCTGG
GTGTGGGACTGTGGTGGGAGATTTCTGTCAGCTGGAAGTCTTTTCCAGAAGGGTGTTAGAGATGGGCACCCATGGCTTTAGTCTCCATACCCCTTCAAGGTTGATAGGGGCCCACACAGCTGGTCAGG
AACCAGCACAGACCTCAGGCTGTGTCTAAAACAAGGTGACTGCACATGCAGGAGCCTGTGCTGGGCCCTGGAGAGCAAATCTGTTCTGTGTCTCACTGGCCTCTCCCTGTCCAGGGGCGTAGTATCAG
TGACCATGTCCCACCTCCTGAGAAAGGTGGAAGAGTCTCACCTGGGGAGTCCAGGTACAAGGGCTGGCCGGCCGTAGATGACTGGTGTGGGGTGGAAAGGCTGCAGAGGCCTCTCCATGGTGGTGAGG
GGTGGAAATAGTGTGCACCTGGGTCCTGGGAGTGGCACCCTGACCAGTTTCAGGGAGGAAGGTGGCAGGGCCCTAGGACAAGTGTGTTAAAAACTTGAGCCCACAGTGTAGACACACTGGTTCCAAAG
ACCCCTCAGGATGTGCCTCCCTTCTCAGATCTGGGCTTTCCCTGTTCCTAAGCATCACCTGGGGGGATCACTCTGGGTCCTCATCTCCAGCCACATGTTCACTCCTCACGTGGGCCTCCCTAACTGTC
CCCCTCAGGGCAAGCCCTTCCTCCCCACTTCCAGAAAGCTGCTCGTTCCCTGGCCATCCCACACCTCTGACCTCGTGCCACTTCCGGGGCCTGTTGGCTTTAACAACTTAGTTTCCTCCCTACCTCGC
AACCCCCTCTGTCTAGAGTGCTCACCTCCCTCCCAGCCTCTGTCTCATACTATTTTTTCTTTCCTCTCAGTACCAAGCGCTGGGACAAGCCAGTCTGTACTCAATGCCTGTGGGATAATAGACGGAGG
AATCTGGAGTTTGGTTGGGTGATTAGCTTTGGAATTGATGGGTCCCAGGGAGCTATCTAAAGTTTTCAGTCACATGAGGGCATGCTCACAGATCTGTGAAAAGATCTGTTGGCTCAGAGAACTAAGAG
ATGAATAAATGTTAGTCCAATGGCCTCATCATGAGATGAGAGGTCAAGAGTTTTGAGTTTCCAGAGGGAGAAGCTACTATTCTAGGCAGCTTGTATGAACTAACTCGTTTATTCCTCACAGCCATTGT
AGGAAATAATCTAACCTCATAAACCCCATTTTAGAGATGAGGAAACAGGCTTAGAGAATTTGACGTAAACTCAAGACCGAAAATCTAGGAACAAGAAAAGCCTGGATTTGAACCAAGCTATCTGATGC
CAGTGTTTTAACTCTCAACCATTGTACTACTTTACCTCCTCATGACCTTTTTTTTTTTTTTCTTGTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTCTGGAGTGCAGTGGCACGATCTCAGCTCACTG
CAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCACCACCATGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTT
GGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCCCCCCCCTCGGCCTCCCAAAGTGCCCATGACCTTTTTATTGTTGGGCAGTGAAAGCCATGGTGAAATGAAGAATGTCCTACTGTCATGTGAT
GTGATCAGAAAACATACTGCCCAGAGTCCCCTGCCCCCACCCCCAAAACCAGTACTTGATCCATCCTTTGACTGTTGTGGCGATTGGCACAAAGGTTGGGCACAGTAGTAGTTAGGCTCATGGGCTCT
GGAGCCAACCTACCTGGATGCTACACATCCCAGCTCTGCCCCTCGCTAGTTTGGTGGCAAGCAACTTAACCTCTCTGCCTTAATTTCTCCAGCAGCACAATGGGAATAATAATAGATCTCGCCTTGTG
GCTCCTTTGCAGATTACATGCGTTAATTATGTAAAGTCAAGCATTAGAATGGTGGCTGTCCACCATGAGTACAACACAAATGCTCGTTCTTAATGATTCAACAAACATGGAATTTCATTAAATCTGAA
ATAAAGGTATTTTGAGAAATTGAA

hide sequence

RefSeq Acc Id:

NR_136208

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	51,571,283 - 51,574,210 (+)	NCBI
CHM1_1	19	52,076,419 - 52,079,381 (+)	NCBI
T2T-CHM13v2.0	19	54,659,955 - 54,662,880 (+)	NCBI

Sequence:

show sequence

GACCATTTAGCTTCTGTTGTTAAGTGGATCTAAGCCTATGTCGCTTACTGGACGCTGAAGTGAT
TGGGAATATTAGCAGTGGGGGTTCTGTAGGGTCAGGAAGGGGCGGCTGGCTTTGGGGGAGTGATGAGGGGCTTGTTGGGGGTGGGGGTGCGTGATAAAGGGATTTCTCGGCTGAAGACGAGGCTGTGA
GGCTTCTGCAGAACCCCCAGGTCAGGCCACATCATTGAGGCTGCAGGATCTCTCTTCATAGCCCAGTACGACTCTCCGCCGTGTCCCTGGTTGGAAAATCCAAACACCTATCCAGCTTCTGGCTCCTG
GGAAAAGTGGAGTTGTCAGCAAGAGAGACCGAGAGTAGAAGCCCAGAGTGGAGATGCCTGCTGATGTGAATTTATCCCAGAAGCCTCAGGTCCTGGGTCCAGAGAAGCAGGATGGATCTTGCGAGGTA
AACAGGGGCAGCCCTGGGGATAGTTCTCCAGAACGTGAGGGCAGACACAGGATGCAGCAGGTCTGGGCTCCCTGCTCCTGAGTCAGTCTTGAGCCTCCTGTCAAGCGAGGACCACAGAGGCTGATGTT
TCCACATTCATAGGCTATCTGTGTTCTAGAGGAAACCATGAACTGGCTGATAAAAGAGGATAGTAGAGGGTTGGCCTTGGGTCAAGAAAGAAGAAACTGTAGTCCCTGGTCTGATCAGAAGCCCCAGT
CATAGGATGGAAAAGCTGACTCTTTCCTGCTAAGCACTGGTTCTGCTCCTTCATCCACCACTGGGTCTTTGAAAAATTTCAAGTGGTCCCCCCCACCAAATTCCTTGCTTGGTCCATGGGGTTTGGCC
CGTTTTTCCTCTGTTCTCATAAGGTGCGGCAAAATCTCCTTCCTTTGTAATTTAAATAGTCACAGGGAGGTAGAGTGAGAAGAGGCTTTTAAGGACCATGTGAAGAGGCTTTTAAACACTTTTTCCTG
TTTAAAAAGGTGAACAAAAAATGCTGGAAAACAGTGTTTCCAGATTGCCCACAGATAGAAATAGTCAGGATTTGGTAACAAGAAATCAGAATTCTTGGTATAGTCAAGATTTCCTGAAATCCTAAATT
ATTCTGTGTATCTCTTGATGCTTTATTTACAAGTCTTTAAATAGTATGTGACTATAATAGTAAACAGTGTACCATTGTTCTGTGATGGGTTTATAACCAAATTTACAGAGATGTTCTGTTTTTTAAAA
AAAGTATAATAAATATGTGTGTTATTATCCTGAACCAA

hide sequence


Protein RefSeqs	NP_009078	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAF87843	(Get FASTA)	NCBI Sequence Viewer
	AAH52997	(Get FASTA)	NCBI Sequence Viewer
	BAA23362	(Get FASTA)	NCBI Sequence Viewer
	BAF85376	(Get FASTA)	NCBI Sequence Viewer
	CAH05700	(Get FASTA)	NCBI Sequence Viewer
	CAR82349	(Get FASTA)	NCBI Sequence Viewer
	EAW72029	(Get FASTA)	NCBI Sequence Viewer
	EAW72030	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000262259
	ENSP00000262259.2
GenBank Protein	Q9Y473	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_009078 ⟸ NM_007147

- UniProtKB:

A8K9H2 (UniProtKB/Swiss-Prot), Q9Y473 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MPADVNLSQKPQVLGPEKQDGSCEASVSFEDVTVDFSREEWQQLDPAQRCLYRDVMLELYSHLFAVGYHIPNPEVIFRMLKEKEPRVEEAEVSHQRCQEREFGLEIPQKEISKKASFQKDMVGEFTRD
GSWCSILEELRLDADRTKKDEQNQIQPMSHSAFFNKKTLNTESNCEYKDPGKMIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDTEQLDDVVGSGQLFSHSSSDACSKNIHTGETFCKGNQ
CRKVCGHKQSLKQHQIHTQKKPDGCSECGGSFTQKSHLFAQQRIHSVGNLHECGKCGKAFMPQLKLSVYLTDHTGDIPCICKECGKVFIQRSELLTHQKTHTRKKPYKCHDCGKAFFQMLSLFRHQRT
HSREKLYECSECGKGFSQNSTLIIHQKIHTGERQYACSECGKAFTQKSTLSLHQRIHSGQKSYVCIECGQAFIQKAHLIVHQRSHTGEKPYQCHNCGKSFISKSQLDIHHRIHTGEKPYECSDCGKTF
TQKSHLNIHQKIHTGERHHVCSECGKAFNQKSILSMHQRIHTGEKPYKCSECGKAFTSKSQFKEHQRIHTGEKPYVCTECGKAFNGRSNFHKHQITHTRERPFVCYKCGKAFVQKSELITHQRTHMGE
KPYECLDCGKSFSKKPQLKVHQRIHTGERPYVCSECGKAFNNRSNFNKHQTTHTRDKSYKCSYSVKGFTKQ

hide sequence

Ensembl Acc Id:

ENSP00000470922 ⟸ ENST00000596504

Ensembl Acc Id:

ENSP00000444424 ⟸ ENST00000545217

Ensembl Acc Id:

ENSP00000262259 ⟸ ENST00000262259

Ensembl Acc Id:

ENSP00000440578 ⟸ ENST00000436511

Protein Domains

KRAB

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9Y473-F1-model_v2	AlphaFold	Q9Y473	1-711	view protein structure

RGD ID:

13205387

Promoter ID:

EPDNEW_H26274

Type:

initiation region

Name:

ZNF175_1

Description:

zinc finger protein 175

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H26275

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	51,571,287 - 51,571,347	EPDNEW

RGD ID:

13205389

Promoter ID:

EPDNEW_H26275

Type:

initiation region

Name:

ZNF175_2

Description:

zinc finger protein 175

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H26274

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	51,571,433 - 51,571,493	EPDNEW

RGD ID:

6796263

Promoter ID:

HG_KWN:30702

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, HeLa_S3, K562, Lymphoblastoid, NB4

Transcripts:

ENST00000262259

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	19	56,766,094 - 56,766,594 (+)	MPROMDB

Database	Acc Id	Source(s)
COSMIC	ZNF175	COSMIC
Ensembl Genes	ENSG00000105497	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000262259	ENTREZGENE
	ENST00000262259.7	UniProtKB/Swiss-Prot
	ENST00000545217	ENTREZGENE
Gene3D-CATH	6.10.140.140	UniProtKB/Swiss-Prot
	Classic Zinc Finger	UniProtKB/Swiss-Prot
GTEx	ENSG00000105497	GTEx
HGNC ID	HGNC:12964	ENTREZGENE
Human Proteome Map	ZNF175	Human Proteome Map
InterPro	KRAB	UniProtKB/Swiss-Prot
	KRAB_dom_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_type	UniProtKB/Swiss-Prot
KEGG Report	hsa:7728	UniProtKB/Swiss-Prot
NCBI Gene	7728	ENTREZGENE
OMIM	601139	OMIM
PANTHER	ZINC FINGER PROTEIN	UniProtKB/Swiss-Prot
	ZINC FINGER PROTEIN 420-LIKE	UniProtKB/Swiss-Prot
Pfam	KRAB	UniProtKB/Swiss-Prot
	zf-C2H2	UniProtKB/Swiss-Prot
PharmGKB	PA37546	PharmGKB
PROSITE	KRAB	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot
SMART	KRAB	UniProtKB/Swiss-Prot
	ZnF_C2H2	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF109640	UniProtKB/Swiss-Prot
	SSF57667	UniProtKB/Swiss-Prot
UniProt	A8K9H2	ENTREZGENE
	F5GZI7_HUMAN	UniProtKB/TrEMBL
	G3V1K8_HUMAN	UniProtKB/TrEMBL
	L8E9H5_HUMAN	UniProtKB/TrEMBL
	M0R013_HUMAN	UniProtKB/TrEMBL
	Q9Y473	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	A8K9H2	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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