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Gene: Gm14444 (predicted gene 14444) Mus musculus

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No known orthologs.

Symbol:

Gm14444

Name:

predicted gene 14444

RGD ID:

10000418

MGI Page

MGI

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus. Predicted to be active in nucleus. Orthologous to several human genes including ZNF486 (zinc finger protein 486); ZNF506 (zinc finger protein 506); and ZNF679 (zinc finger protein 679).

Type:

protein-coding

RefSeq Status:

PREDICTED

Previously known as:

uncharacterized protein LOC105244402; zinc finger protein 120-like; zinc finger protein 239-like

RGD Orthologs

Alliance Orthologs

More Info

homologs ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	174,858,456 - 174,861,241 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	174,852,002 - 174,861,041 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	175,016,710 - 175,019,448 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	175,010,241 - 175,019,248 (+)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
Cytogenetic Map	2	H4	NCBI
cM Map	2	98.22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleolus (ISO)

nucleus (IBA,IEA)

Molecular Function

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:21873635

Genomics

Variants

Variants in Gm14444
89 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	160
Count of miRNA genes:	143
Interacting mature miRNAs:	147
Transcripts:	ENSMUST00000109069, ENSMUST00000109070
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300688	Nidd2k_m	Nidd2 on KK-A (mouse)			Not determined		2	158078337	178442452	Mouse
1301783	Bhr1_m	bronchial hyperresponsiveness 1 (mouse)			Not determined		2	142593476	178442452	Mouse
12790983	Bwq12_m	body weight QTL 12 (mouse)					2	148238204	181755017	Mouse
11038701	Ltpr2e_m	Leishmania tropica response 2e (mouse)					2	150212221	181755017	Mouse
1301019	Bmd6_m	bone mineral density 6 (mouse)			Not determined		2	151778297	181755017	Mouse
4142450	Lmr16_m	leishmaniasis resistance 16 (mouse)			Not determined		2	150212221	181755017	Mouse
1301085	Lrnx10_m	learning-contextual 10 (mouse)			Not determined		2	150212221	181755017	Mouse
1300867	Lore2_m	loss of righting induced by ethanol 2 (mouse)			Not determined		2	144515861	180896594	Mouse
1558917	Gct8_m	granulosa cell tumorigenesis 8 (mouse)			Not determined		2	149236907	181755017	Mouse
1300806	Aod4_m	autoimmune ovarian dysgenesis 4 (mouse)			Not determined		2	145228719	179228841	Mouse
1300676	Prdt2_m	prion disease incubation time 2 (mouse)			Not determined		2	164515154	181755017	Mouse
1558991	Tailq4_m	tail length QTL 4 (mouse)			Not determined		2	162736926	178442452	Mouse
14747002	Mancz3_m	mandible centroid size 3 (mouse)					2	152329820	181755017	Mouse
1300751	Bdt1_m	bone density traits 1 (mouse)			Not determined		2	149988902	181755017	Mouse
1300622	Cfld1_m	cystic fibrosis lung disease 1 (mouse)			Not determined		2	155823920	181755017	Mouse
12910811	Pwbwq3_m	pre-weaning body weight QTL 3 (mouse)					2	169794802	178920791	Mouse
1302003	Sluc17_m	susceptibility to lung cancer 17 (mouse)			Not determined		2	162433493	181755017	Mouse
12738409	Lfibq1_m	liver fibrosis QTL 1 (mouse)					2	167716420	179207088	Mouse
1302013	Tbbmd3_m	total body bone mineral density 3 (mouse)			Not determined		2	145196949	179197085	Mouse
5491196	Mobq6_m	multigenic obesity QTL 6 (mouse)			Not determined		2	85724269	180896594	Mouse
1357435	Epfq2_m	epididymal fat pad weight QTL 2 (mouse)			Not determined		2	162736926	178442452	Mouse
12801456	Intmrm1_m	intima/media ratio modifier 1 (mouse)					2	142428347	176428450	Mouse
1357537	Lith12_m	lithogenic gene 12 (mouse)			Not determined		2	156196464	181755017	Mouse
12801461	Intim1_m	intima modifier 1 (mouse)					2	142428347	176428450	Mouse
1301348	Alcp5_m	alcohol preference locus 5 (mouse)			Not determined		2	163486407	181755017	Mouse
1301865	Hdlq19_m	HDL QTL 19 (mouse)			Not determined		2	145518775	179518926	Mouse
4142211	Nilac3_m	nicotine induced locomotor activity 3 (mouse)			Not determined		2	148664893	181755017	Mouse
1301677	Alcp6_m	alcohol preference locus 6 (mouse)			Not determined		2	163486407	181755017	Mouse

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001378705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017319402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AL845494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000109069 ⟹ ENSMUSP00000104697

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	174,852,034 - 174,859,064 (+)	Ensembl
GRCm38.p6 Ensembl	2	175,010,241 - 175,017,612 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000109070 ⟹ ENSMUSP00000104698

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	174,852,002 - 174,861,041 (+)	Ensembl
GRCm38.p6 Ensembl	2	175,010,319 - 175,019,248 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000249360 ⟹ ENSMUSP00000159718

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	2	174,852,034 - 174,859,064 (+)	Ensembl

RefSeq Acc Id:

NM_001378705 ⟹ NP_001365634

RefSeq Status:

PREDICTED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	174,858,522 - 174,861,241 (+)	NCBI

Sequence:

show sequence

TGATGGTAGAGACCTATAGGAATCTCACAGCTATAGGTTACATTTGGGAAGAACATACAAGTGA
AGACCATTTTCAAAATTCTAGAAGTCATGGAAGGCATGAAAGAAGTTGTTCTGCAGAGCAACTC
TCTGAGTTTATTCACTGTGGTAAAGCCTTTGCATATGAGAGTGGTAGTCAAAGGCATCAAATAA
AACATACTGGAGAGAAACACCATGACTGTAACCAATGTGGTAAAGCTTTTAAAAGAAGGAGTGA
CATCCAAATACATAAGCAAACACATACAGGAGAGAAACCCTATGAATGTAACCAATGTGGAAAA
GCCTTTGCAGGAAGTGGTGACCTCCAAAAACATAAACGAACACATACAGGAGAGAAACCCTACA
AATGTAACCAATGTGGTAAAGCCTTTTCACAAAGCAGTCATCTCCGAATACATAAGCGAACACA
TACAGGAGAGAAACCCTATGAATGTAAACAATGTGGTAAAGCCTTTGCACATAGCAGTCATCTC
CACATACATGAGCGAACACATACAAGAGAGAAACCCTATGAATGTAAACAATGTGGTAAAGCCT
TTTCACAAAGCAGTCATCTCCAAATCCATAAGCGAACACATACAGGAGAGAAACCCTATGAATG
TAAACAATGTGGTAAAGCCTTTGCACAAAGCAGTCATCTTCGAATACATAAGCAAACACATACA
GGAGAGAAACCCTATGAATGTAAACAATGTGGTAAAGGCTTTGCAGGAAGTGGTGACCTCCAAA
AACATAAACAAACACATACAGGAGAGAAACCATATGAATGTAAACAATGTGGTAAAGCCTTTTC
AAGAAAGAGTGACCTCCAAAAACATAAACGAACACATACAGGAGAGAAACCCTATGAATGTAAA
CAATGTGGTAAAGCTTTTGCACAAAGCAGTACTCTCCAAATCCATAAGAGAACACATACAGGAG
AGAAACCATATGAATGTAAACAATGTGGTAAAGCCTTTGCAGGAAGCAGTGGTCTCCAATGCCA
TAAAAGATCACATACAGGAGAGACACCATATGAATGTAACCAAGGTGGTAAACCCTTTGAAGGA
AGCAGTGGTCTTGAATATAATAATCGAACACAAACAGCTGAAAAACCCTATGAATGTAACCAAT
GTGGTAAAGTCTTTGCAGGAAGGAGTGACCTTTAAAGAGAAAAGACCATACAGGAGAGAAACTC
TATGAAAGTATCTGATGTTGTAAAGCCTTTGCAGCAAGCATTGATCTCCAAGTACATAAATGAA
CACATACCAGAGAGGAACCTTTTAAATGTAACCAAAGTGGTAAAGCTTTTTTGAAGGGTAAAAG
GCTGGAAAACAATTTTCCAAGCAAATGGTCTGAAGAAACAAGC

hide sequence

RefSeq Acc Id:

XM_017319402 ⟹ XP_017174891

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	2	174,858,456 - 174,861,241 (+)	NCBI

Sequence:

show sequence

ATGTGAACTTCACTCAGGAAGAGTGGGCTTTGCTGGATCCTTCTCATAAAAATCTCTACAAAGA
TGTGATGGTAGAGACCTATAGGAATCTCACAGCTATAGGTTACATTTGGGAAGAACATACAAGT
GAAGACCATTTTCAAAATTCTAGAAGTCATGGAAGGCATGAAAGAAGTTGTTCTGCAGAGCAAC
TCTCTGAGTTTATTCACTGTGGTAAAGCCTTTGCATATGAGAGTGGTAGTCAAAGGCATCAAAT
AAAACATACTGGAGAGAAACACCATGACTGTAACCAATGTGGTAAAGCTTTTAAAAGAAGGAGT
GACATCCAAATACATAAGCAAACACATACAGGAGAGAAACCCTATGAATGTAACCAATGTGGAA
AAGCCTTTGCAGGAAGTGGTGACCTCCAAAAACATAAACGAACACATACAGGAGAGAAACCATA
TGAATGTAAACAATGTGGTAAAGCCTTTGCAGGAAGCAGTGGTCTCCAATGCCATAAAAGATCA
CATACAGGAGAGACACCATATGAATGTAACCAAGGTGGTAAACCCTTTGAAGGAAGCAGTGGTC
TTGAATATAATAATCGAACACAAACAGCTGAAAAACCCTATGAATGTAACCAATGTGGTAAAGT
CTTTGCAGGAAGGAGTGACCTTTAAAGAGAAAAGACCATACAGGAGAGAAACTCTATGAAAGTA
TCTGATGTTGTAAAGCCTTTGCAGCAAGCATTGATCTCCAAGTACATAAATGAACACATACCAG
AGAGGAACCTTTTAAATGTAACCAAAGTGGTAAAGCTTTTTTGAAGGGTAAAAGGCTGGAAAAC
AATTTTCCAAGCAAATGGTCTGAAGAAACAAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001365634	(Get FASTA)	NCBI Sequence Viewer
	XP_017174891	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000104571.2
	ENSMUSP00000104697.2
	ENSMUSP00000104698
	ENSMUSP00000104698.3
	ENSMUSP00000159717.1
	ENSMUSP00000159718.1

Ensembl Acc Id:

ENSMUSP00000104697 ⟸ ENSMUST00000109069

Ensembl Acc Id:

ENSMUSP00000104698 ⟸ ENSMUST00000109070

Ensembl Acc Id:

ENSMUSP00000159718 ⟸ ENSMUST00000249360

RefSeq Acc Id:

XP_017174891 ⟸ XM_017319402

- Peptide Label:

isoform X1

- Sequence:

show sequence

MVETYRNLTAIGYIWEEHTSEDHFQNSRSHGRHERSCSAEQLSEFIHCGKAFAYESGSQRHQIK
HTGEKHHDCNQCGKAFKRRSDIQIHKQTHTGEKPYECNQCGKAFAGSGDLQKHKRTHTGEKPYE
CKQCGKAFAGSSGLQCHKRSHTGETPYECNQGGKPFEGSSGLEYNNRTQTAEKPYECNQCGKVF
AGRSDL

hide sequence

RefSeq Acc Id:

NP_001365634 ⟸ NM_001378705

Protein Domains

C2H2-type KRAB

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A2ARW3-F1-model_v2	AlphaFold	A2ARW3	1-426	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:3652325	AgrOrtholog
Ensembl Genes	ENSMUSG00000078865	UniProtKB/TrEMBL
	ENSMUSG00000078906	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000108943.2	UniProtKB/TrEMBL
	ENSMUST00000109069.9	UniProtKB/TrEMBL
	ENSMUST00000109070	ENTREZGENE
	ENSMUST00000109070.4	UniProtKB/TrEMBL
	ENSMUST00000249359.1	UniProtKB/TrEMBL
	ENSMUST00000249360.1	UniProtKB/TrEMBL
Gene3D-CATH	6.10.140.140	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	C2H2-ZF_domain	UniProtKB/TrEMBL
	KRAB_dom_sf	UniProtKB/TrEMBL
	Krueppel-associated_box	UniProtKB/TrEMBL
	Znf_C2H2-type	UniProtKB/TrEMBL
	Znf_C2H2/integrase_DNA-bd	UniProtKB/TrEMBL
	Znf_C2H2_sf	UniProtKB/TrEMBL
MGD	MGI:3652325	ENTREZGENE
NCBI Gene	Gm14444	ENTREZGENE
PANTHER	FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED	UniProtKB/TrEMBL
	RIKEN CDNA 6720489N17 GENE-RELATED	UniProtKB/TrEMBL
	ZINC FINGER PROTEIN 977	UniProtKB/TrEMBL
	ZNF44 PROTEIN	UniProtKB/TrEMBL
Pfam	KRAB	UniProtKB/TrEMBL
	zf-C2H2	UniProtKB/TrEMBL
	zf-H2C2_2	UniProtKB/TrEMBL
PhenoGen	Gm14444	PhenoGen
PROSITE	KRAB	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_1	UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/TrEMBL
SMART	KRAB	UniProtKB/TrEMBL
	ZnF_C2H2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF109640	UniProtKB/TrEMBL
	SSF57667	UniProtKB/TrEMBL
UniProt	A2ARW3_MOUSE	UniProtKB/TrEMBL
	A2ARW4_MOUSE	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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