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Gene: ZNF860 (zinc finger protein 860) Homo sapiens

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Symbol:

ZNF860

Name:

zinc finger protein 860

RGD ID:

2301111

HGNC Page

HGNC:34513

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

FLJ60236; LOC124906225; uncharacterized LOC124906225

RGD Orthologs

Bonobo

Dog

Green Monkey

Alliance Orthologs

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	31,981,750 - 32,006,443 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	31,981,750 - 31,991,723 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	32,023,242 - 32,033,215 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	32,005,619 - 32,008,236 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	31,959,854 - 31,969,707 (+)	NCBI		Celera
Cytogenetic Map	3	p23-p22.3	NCBI
HuRef	3	31,963,867 - 31,973,829 (+)	NCBI		HuRef
CHM1_1	3	31,973,909 - 31,983,871 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	31,984,716 - 32,009,928 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF860	Human	actinomycin D	increases expression	EXP		6480464	Dactinomycin results in increased expression of ZNF860 mRNA	CTD	PMID:38460933
ZNF860	Human	actinomycin D	multiple interactions	EXP		6480464	[Dactinomycin co-treated with nutlin 3] results in increased expression of ZNF860 mRNA	CTD	PMID:38460933
ZNF860	Human	aflatoxin B1	decreases methylation	EXP		6480464	Aflatoxin B1 results in decreased methylation of ZNF860 gene	CTD	PMID:27153756
ZNF860	Human	benzo[a]pyrene	affects methylation	EXP		6480464	Benzo(a)pyrene affects the methylation of ZNF860 5' UTR	CTD	PMID:27901495
ZNF860	Human	benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of ZNF860 mRNA	CTD	PMID:32234424
ZNF860	Human	ethylparaben	increases expression	EXP		6480464	ethyl-p-hydroxybenzoate results in increased expression of ZNF860 mRNA	CTD	PMID:37690743
ZNF860	Human	Licochalcone B	decreases expression	EXP		6480464	licochalcone B results in decreased expression of ZNF860 mRNA	CTD	PMID:33647349
ZNF860	Human	Nutlin-3	multiple interactions	EXP		6480464	[Dactinomycin co-treated with nutlin 3] results in increased expression of ZNF860 mRNA	CTD	PMID:38460933
ZNF860	Human	temozolomide	decreases expression	EXP		6480464	Temozolomide results in decreased expression of ZNF860 mRNA	CTD	PMID:31758290
ZNF860	Human	triphenyl phosphate	affects expression	EXP		6480464	triphenyl phosphate affects the expression of ZNF860 mRNA	CTD	PMID:37042841
ZNF860	Human	urethane	decreases expression	EXP		6480464	Urethane results in decreased expression of ZNF860 mRNA	CTD	PMID:28818685

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF860	Human	regulation of DNA-templated transcription	involved_in	IEA	InterPro:IPR001909\|InterPro:IPR036051	150520179		InterPro	GO_REF:0000002
ZNF860	Human	regulation of transcription by RNA polymerase II	involved_in	IBA	MGI:1351476\|MGI:1916754\|MGI:2142347\|MGI:2389445\|MGI:3044162\|PANTHER:PTN001225435\|RGD:2967\|RGD:2985\|UniProtKB:P52737\|UniProtKB:P52738\|UniProtKB:Q96CS4\|UniProtKB:Q96RE9\|UniProtKB:Q9HCX3	150520179		GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF860	Human	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	150520179		UniProt	GO_REF:0000043
ZNF860	Human	nucleus	is_active_in	IBA	MGI:105921\|MGI:1328322\|MGI:1353621\|MGI:1916754\|MGI:2142347\|MGI:2143362\|MGI:2389445\|MGI:2444763\|MGI:3040700\|MGI:99206\|PANTHER:PTN001225435\|UniProtKB:O60765\|UniProtKB:P17014\|UniProtKB:P17020\|UniProtKB:P17032\|UniProtKB:Q09FC8\|UniProtKB:Q15072\|UniProtKB:Q16587\|UniProtKB:Q3ZCT1\|UniProtKB:Q5FWF6\|UniProtKB:Q6ECI4\|UniProtKB:Q7Z3V5\|UniProtKB:Q86Y25\|UniProtKB:Q8IZ26\|UniProtKB:Q8N720\|UniProtKB:Q8NDQ6\|UniProtKB:Q8TF45\|UniProtKB:Q8WV37\|UniProtKB:Q96CS4\|UniProtKB:Q96RE9\|UniProtKB:Q9BX82\|UniProtKB:Q9ULD5\|UniProtKB:Q9Y2P7	150520179		GO_Central	GO_REF:0000033
ZNF860	Human	nucleus	located_in	IEA	ARBA:ARBA00026330	150520179		UniProt	GO_REF:0000117
ZNF860	Human	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	150520179		UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ZNF860	Human	DNA binding	enables	IEA	UniProtKB-KW:KW-0238	150520179		UniProt	GO_REF:0000043
ZNF860	Human	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA	PANTHER:PTN001225435\|UniProtKB:P35789\|UniProtKB:P52738\|UniProtKB:Q86Y25\|UniProtKB:Q96RE9	150520179		GO_Central	GO_REF:0000033
ZNF860	Human	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
ZNF860	Human	protein binding	enables	IPI	UniProtKB:P60411\|UniProtKB:Q8NHQ1	150520179	PMID:32296183	IntAct	PMID:32296183
ZNF860	Human	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA	MGI:1916754\|PANTHER:PTN001225435	150520179		GO_Central	GO_REF:0000033
ZNF860	Human	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	150520179		UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:16641997	PMID:21873635	PMID:22658674	PMID:24347629	PMID:30767193	PMID:32296183

ZNF860
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	31,981,750 - 32,006,443 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	31,981,750 - 31,991,723 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	32,023,242 - 32,033,215 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	32,005,619 - 32,008,236 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	31,959,854 - 31,969,707 (+)	NCBI		Celera
Cytogenetic Map	3	p23-p22.3	NCBI
HuRef	3	31,963,867 - 31,973,829 (+)	NCBI		HuRef
CHM1_1	3	31,973,909 - 31,983,871 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	31,984,716 - 32,009,928 (+)	NCBI		T2T-CHM13v2.0

ZNF860
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	31,961,912 - 31,971,808 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	31,966,679 - 31,978,944 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	31,902,430 - 31,912,637 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	32,219,227 - 32,229,063 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	32,226,510 - 32,228,406 (+)	Ensembl	panpan1.1		panPan2

LOC106558995
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	104,868,965 - 104,886,040 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	104,442,790 - 104,459,749 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	105,378,598 - 105,395,378 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	1	105,051,359 - 105,068,130 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	104,705,582 - 104,722,346 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	105,493,130 - 105,509,870 (-)	NCBI		UU_Cfam_GSD_1.0

ZNF860
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	76,516,703 - 76,519,681 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666041	49,860,974 - 49,872,670 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants in ZNF860
57 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 3p26.3-22.2(chr3:52266-37148076)x3	copy number gain	See cases [RCV000051097]	Chr3:52266..37148076 [GRCh38] Chr3:93949..37189567 [GRCh37] Chr3:68949..37164571 [NCBI36] Chr3:3p26.3-22.2	pathogenic
GRCh38/hg38 3p25.3-22.2(chr3:11463328-38919543)x3	copy number gain	See cases [RCV000051720]	Chr3:11463328..38919543 [GRCh38] Chr3:11504802..38961034 [GRCh37] Chr3:11479802..38936038 [NCBI36] Chr3:3p25.3-22.2	pathogenic
GRCh38/hg38 3p26.3-22.1(chr3:53308-41381521)x3	copy number gain	See cases [RCV000141810]	Chr3:53308..41381521 [GRCh38] Chr3:94991..41423012 [GRCh37] Chr3:69991..41398016 [NCBI36] Chr3:3p26.3-22.1	pathogenic
GRCh37/hg19 3p24.1-22.3(chr3:29689082-34233218)x1	copy number loss	See cases [RCV000240426]	Chr3:29689082..34233218 [GRCh37] Chr3:3p24.1-22.3	pathogenic
GRCh37/hg19 3p24.2-22.3(chr3:25045365-32691140)x1	copy number loss	See cases [RCV000447472]	Chr3:25045365..32691140 [GRCh37] Chr3:3p24.2-22.3	likely pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181)x3	copy number gain	See cases [RCV000448528]	Chr3:61891..36710181 [GRCh37] Chr3:3p26.3-22.2	pathogenic
GRCh37/hg19 3p26.3-22.3(chr3:61891-33958201)x3	copy number gain	See cases [RCV000510429]	Chr3:61891..33958201 [GRCh37] Chr3:3p26.3-22.3	pathogenic
GRCh37/hg19 3p26.3-22.2(chr3:61891-37459464)x3	copy number gain	See cases [RCV000511463]	Chr3:61891..37459464 [GRCh37] Chr3:3p26.3-22.2	pathogenic
NM_001137674.3(ZNF860):c.1504G>T (p.Ala502Ser)	single nucleotide variant	not specified [RCV004318196]	Chr3:31990583 [GRCh38] Chr3:32032075 [GRCh37] Chr3:3p23	uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3	copy number gain	See cases [RCV000511055]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)	copy number gain	See cases [RCV000512358]	Chr3:61892..197851986 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p24.3-21.31(chr3:16923595-45249923)x2,3	copy number gain	not provided [RCV000682249]	Chr3:16923595..45249923 [GRCh37] Chr3:3p24.3-21.31	pathogenic
GRCh37/hg19 3p23-22.3(chr3:31854742-32312549)x3	copy number gain	not provided [RCV000682253]	Chr3:31854742..32312549 [GRCh37] Chr3:3p23-22.3	uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3	copy number gain	not provided [RCV000742138]	Chr3:61495..197838262 [GRCh37] Chr3:3p26.3-q29	pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3	copy number gain	not provided [RCV000742133]	Chr3:60174..197948027 [GRCh37] Chr3:3p26.3-q29	pathogenic
NM_001137674.3(ZNF860):c.1874A>G (p.His625Arg)	single nucleotide variant	not specified [RCV004281586]	Chr3:31990953 [GRCh38] Chr3:32032445 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.573G>A (p.Thr191=)	single nucleotide variant	not provided [RCV000955312]	Chr3:31989652 [GRCh38] Chr3:32031144 [GRCh37] Chr3:3p23	benign
NM_001137674.3(ZNF860):c.1071C>T (p.Leu357=)	single nucleotide variant	not provided [RCV000955313]	Chr3:31990150 [GRCh38] Chr3:32031642 [GRCh37] Chr3:3p23	benign
NM_001137674.3(ZNF860):c.1880G>A (p.Arg627His)	single nucleotide variant	not provided [RCV000955314]	Chr3:31990959 [GRCh38] Chr3:32032451 [GRCh37] Chr3:3p23	benign
GRCh37/hg19 3p23-22.3(chr3:31988552-32303140)x3	copy number gain	not provided [RCV001259692]	Chr3:31988552..32303140 [GRCh37] Chr3:3p23-22.3	uncertain significance
GRCh37/hg19 3p26.3-22.2(chr3:61891-36710181)	copy number gain	not specified [RCV002053300]	Chr3:61891..36710181 [GRCh37] Chr3:3p26.3-22.2	pathogenic
GRCh37/hg19 3p23-22.3(chr3:31859973-33127072)	copy number gain	not specified [RCV002053337]	Chr3:31859973..33127072 [GRCh37] Chr3:3p23-22.3	uncertain significance
GRCh37/hg19 3p24.2-22.3(chr3:25045365-32691140)	copy number loss	not specified [RCV002053334]	Chr3:25045365..32691140 [GRCh37] Chr3:3p24.2-22.3	likely pathogenic
NC_000003.11:g.(?_16710965)_(41275270_?)del	deletion	not provided [RCV001958625]	Chr3:16710965..41275270 [GRCh37] Chr3:3p24.3-22.1	pathogenic
NM_001137674.3(ZNF860):c.833G>C (p.Arg278Thr)	single nucleotide variant	not specified [RCV004307264]	Chr3:31989912 [GRCh38] Chr3:32031404 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.209T>G (p.Met70Arg)	single nucleotide variant	not specified [RCV004327748]	Chr3:31989288 [GRCh38] Chr3:32030780 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1352A>T (p.Glu451Val)	single nucleotide variant	not specified [RCV004092023]	Chr3:31990431 [GRCh38] Chr3:32031923 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.995A>G (p.His332Arg)	single nucleotide variant	not specified [RCV004127282]	Chr3:31990074 [GRCh38] Chr3:32031566 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.424G>A (p.Asp142Asn)	single nucleotide variant	not specified [RCV004241045]	Chr3:31989503 [GRCh38] Chr3:32030995 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.167A>G (p.Asn56Ser)	single nucleotide variant	not specified [RCV004230018]	Chr3:31989246 [GRCh38] Chr3:32030738 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1825C>T (p.Arg609Cys)	single nucleotide variant	not specified [RCV004209184]	Chr3:31990904 [GRCh38] Chr3:32032396 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1263T>A (p.Asn421Lys)	single nucleotide variant	not specified [RCV004177740]	Chr3:31990342 [GRCh38] Chr3:32031834 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1256T>G (p.Ile419Ser)	single nucleotide variant	not specified [RCV004107999]	Chr3:31990335 [GRCh38] Chr3:32031827 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1337G>A (p.Arg446Gln)	single nucleotide variant	not specified [RCV004240568]	Chr3:31990416 [GRCh38] Chr3:32031908 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.845G>C (p.Gly282Ala)	single nucleotide variant	not specified [RCV004104914]	Chr3:31989924 [GRCh38] Chr3:32031416 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.456A>C (p.Lys152Asn)	single nucleotide variant	not specified [RCV004126283]	Chr3:31989535 [GRCh38] Chr3:32031027 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1852G>A (p.Gly618Arg)	single nucleotide variant	not specified [RCV004134020]	Chr3:31990931 [GRCh38] Chr3:32032423 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.933G>T (p.Glu311Asp)	single nucleotide variant	not specified [RCV004169324]	Chr3:31990012 [GRCh38] Chr3:32031504 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.233C>G (p.Ala78Gly)	single nucleotide variant	not specified [RCV004091673]	Chr3:31989312 [GRCh38] Chr3:32030804 [GRCh37] Chr3:3p23	likely benign
NM_001137674.3(ZNF860):c.649C>T (p.Leu217Phe)	single nucleotide variant	not specified [RCV004242346]	Chr3:31989728 [GRCh38] Chr3:32031220 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.746A>C (p.Gln249Pro)	single nucleotide variant	not specified [RCV004148685]	Chr3:31989825 [GRCh38] Chr3:32031317 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.496C>T (p.Leu166Phe)	single nucleotide variant	not specified [RCV004114336]	Chr3:31989575 [GRCh38] Chr3:32031067 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1673G>T (p.Arg558Ile)	single nucleotide variant	not specified [RCV004122999]	Chr3:31990752 [GRCh38] Chr3:32032244 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.131C>T (p.Thr44Met)	single nucleotide variant	not specified [RCV004091817]	Chr3:31989210 [GRCh38] Chr3:32030702 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.812G>A (p.Arg271Gln)	single nucleotide variant	not specified [RCV004276976]	Chr3:31989891 [GRCh38] Chr3:32031383 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.122T>C (p.Leu41Pro)	single nucleotide variant	not specified [RCV004267479]	Chr3:31989201 [GRCh38] Chr3:32030693 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1313G>A (p.Arg438His)	single nucleotide variant	not specified [RCV004248366]	Chr3:31990392 [GRCh38] Chr3:32031884 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.818T>G (p.Leu273Arg)	single nucleotide variant	not specified [RCV004283314]	Chr3:31989897 [GRCh38] Chr3:32031389 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1579C>T (p.Arg527Cys)	single nucleotide variant	not specified [RCV004253995]	Chr3:31990658 [GRCh38] Chr3:32032150 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.415G>A (p.Asp139Asn)	single nucleotide variant	not specified [RCV004349661]	Chr3:31989494 [GRCh38] Chr3:32030986 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.898A>C (p.Asn300His)	single nucleotide variant	not specified [RCV004351289]	Chr3:31989977 [GRCh38] Chr3:32031469 [GRCh37] Chr3:3p23	uncertain significance
GRCh37/hg19 3p26.3-22.3(chr3:61891-33946644)x3	copy number gain	not specified [RCV003986437]	Chr3:61891..33946644 [GRCh37] Chr3:3p26.3-22.3	pathogenic
NM_001137674.3(ZNF860):c.1703G>A (p.Cys568Tyr)	single nucleotide variant	not specified [RCV004495238]	Chr3:31990782 [GRCh38] Chr3:32032274 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1841G>T (p.Arg614Ile)	single nucleotide variant	not specified [RCV004495239]	Chr3:31990920 [GRCh38] Chr3:32032412 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.210G>A (p.Met70Ile)	single nucleotide variant	not specified [RCV004495240]	Chr3:31989289 [GRCh38] Chr3:32030781 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.973C>T (p.Arg325Cys)	single nucleotide variant	not specified [RCV004495242]	Chr3:31990052 [GRCh38] Chr3:32031544 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1013G>A (p.Gly338Glu)	single nucleotide variant	not specified [RCV004495237]	Chr3:31990092 [GRCh38] Chr3:32031584 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.496C>G (p.Leu166Val)	single nucleotide variant	not specified [RCV004495241]	Chr3:31989575 [GRCh38] Chr3:32031067 [GRCh37] Chr3:3p23	uncertain significance
GRCh37/hg19 3p26.3-22.3(chr3:60000-34461438)x3	copy number gain	not provided [RCV004577500]	Chr3:60000..34461438 [GRCh37] Chr3:3p26.3-22.3	pathogenic
NM_001137674.3(ZNF860):c.596C>T (p.Pro199Leu)	single nucleotide variant	not specified [RCV004603637]	Chr3:31989675 [GRCh38] Chr3:32031167 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1349G>A (p.Gly450Glu)	single nucleotide variant	not specified [RCV004603632]	Chr3:31990428 [GRCh38] Chr3:32031920 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.764G>A (p.Gly255Glu)	single nucleotide variant	not specified [RCV004603634]	Chr3:31989843 [GRCh38] Chr3:32031335 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1289A>G (p.Lys430Arg)	single nucleotide variant	not specified [RCV004603635]	Chr3:31990368 [GRCh38] Chr3:32031860 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.131C>A (p.Thr44Lys)	single nucleotide variant	not specified [RCV004603633]	Chr3:31989210 [GRCh38] Chr3:32030702 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.109G>A (p.Glu37Lys)	single nucleotide variant	not specified [RCV004603638]	Chr3:31989188 [GRCh38] Chr3:32030680 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1619G>T (p.Cys540Phe)	single nucleotide variant	not specified [RCV004891779]	Chr3:31990698 [GRCh38] Chr3:32032190 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1474C>T (p.Arg492Cys)	single nucleotide variant	not specified [RCV004891780]	Chr3:31990553 [GRCh38] Chr3:32032045 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.172A>G (p.Arg58Gly)	single nucleotide variant	not specified [RCV004891781]	Chr3:31989251 [GRCh38] Chr3:32030743 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.587C>T (p.Ser196Phe)	single nucleotide variant	not specified [RCV004891782]	Chr3:31989666 [GRCh38] Chr3:32031158 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.497T>C (p.Leu166Pro)	single nucleotide variant	not specified [RCV004891783]	Chr3:31989576 [GRCh38] Chr3:32031068 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.988G>C (p.Glu330Gln)	single nucleotide variant	not specified [RCV004891778]	Chr3:31990067 [GRCh38] Chr3:32031559 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1222A>G (p.Ser408Gly)	single nucleotide variant	not specified [RCV004891772]	Chr3:31990301 [GRCh38] Chr3:32031793 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1658A>G (p.His553Arg)	single nucleotide variant	not specified [RCV004891773]	Chr3:31990737 [GRCh38] Chr3:32032229 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1312C>T (p.Arg438Cys)	single nucleotide variant	not specified [RCV004891774]	Chr3:31990391 [GRCh38] Chr3:32031883 [GRCh37] Chr3:3p23	likely benign
NM_001137674.3(ZNF860):c.1118A>G (p.Asn373Ser)	single nucleotide variant	not specified [RCV004891775]	Chr3:31990197 [GRCh38] Chr3:32031689 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1864T>C (p.Tyr622His)	single nucleotide variant	not specified [RCV004891776]	Chr3:31990943 [GRCh38] Chr3:32032435 [GRCh37] Chr3:3p23	uncertain significance
NM_001137674.3(ZNF860):c.1390C>T (p.His464Tyr)	single nucleotide variant	not specified [RCV004891777]	Chr3:31990469 [GRCh38] Chr3:32031961 [GRCh37] Chr3:3p23	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	283
Count of miRNA genes:	264
Interacting mature miRNAs:	273
Transcripts:	ENST00000360311, ENST00000489408
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597616505	GWAS1673365_H	Abnormality of the gastrointestinal tract QTL GWAS1673365 (human)		5e-12	Abnormality of the gastrointestinal tract		3	31995683	31995684	Human
597504129	GWAS1600203_H	N-acetylneuraminate measurement QTL GWAS1600203 (human)		0.0000001	N-acetylneuraminate measurement		3	32000477	32000478	Human
2316061	GLUCO194_H	Glucose level QTL 194 (human)		0.02	Glucose level		3	23380774	49380774	Human

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system	visual system
1203	2432	2653	2198	4840	1619	2234	5	523	1410	364	2255	6467	5869	34	3603	1	851	1740	1601	174	1


RefSeq Transcripts	NM_001137674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017006299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047448072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047448073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047448074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346428	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054346429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001740138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_007073404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_007073405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_007095674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC094019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC108485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK294003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ268755	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000360311 ⟹ ENSP00000373274

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	31,981,750 - 31,991,723 (+)	Ensembl

Ensembl Acc Id:

ENST00000489408

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	3	31,981,771 - 31,988,925 (+)	Ensembl

RefSeq Acc Id:

NM_001137674 ⟹ NP_001131146

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	31,981,750 - 31,991,723 (+)	NCBI
GRCh37	3	32,023,266 - 32,033,228 (+)	ENTREZGENE
Celera	3	31,959,854 - 31,969,707 (+)	RGD
HuRef	3	31,963,867 - 31,973,829 (+)	ENTREZGENE
CHM1_1	3	31,973,909 - 31,983,871 (+)	NCBI
T2T-CHM13v2.0	3	31,984,716 - 31,994,689 (+)	NCBI

Sequence:

show sequence

GCACACTCCCTCTCTCGGTCTTCCGCACACGATGCTGCGCCAGACGCTCCTACACAGTAACCTGGAAATTATCACCGGCGGAGCAAAGTCACAGCTCAGGGAGGCCCTCCGCGTTGTCTGGCGGAGGA
GGGGAGTGGCAGGTGATCCTCACAGTCACTCTAGGAAAGCCAGCTGCCATGACATAAGGATACTCAGGCCACCAATGGATAGCCCAGGCAGGAGGCATGAAGGTGTGCCAGCCACTGTGTCAGTCACC
TTATAAGCAGATTTTCTGAGACCTGCTAACAGCCATGTGAGTGACCTTGGAAGTAGGTTGTCACCAGTCAAGCCTTGAGATGACTGCAGCCATGACCCACAGCTTGACTACAACCCAGAGAGACACTG
AGCCAGGAACACCCAGCTGAAGTGCCTCCAAACCCCGACCCACAGCGACTGTGAGATAATCAGTGTTTGTTGCCTTAAGCCACGAAGTTTGTGATAATTTGTTTCTCGGAAACAGATAACTAATACAG
AGCAGGAAGCAGATCGCCTCAGTGAAGGTCACACTGCAGCACTATTGATTTCTAAAGACTCATGTTACGTGAGGAAGCAGCTCAGAAGAGGAAAGAAAAGGAGCCAGGCATGGCTCTTCCTCAGGGAC
ACTTGACTTTTAGGGATGTGGCTATAGAATTCTCTTTGGAGGAGTGGAAATGCCTGGACCCTACGCAGAGGGCTTTATACAGGGCCATGATGTTGGAGAACTACAGGAACCTGCATTCTGTGGATATC
TCTTCCAAATGCATGATGAAGAAGTTCTCATCAACAGCGCAAGGCAATACAGAAGTGGACACAGGGACATTAGAAAGACATGAAAGTCATCACATTGGAGATTTTTGCTTCCAGAAAATTGGGAAAGA
TATTCATGACTTTGAGTTTCAATGGCAAGAAGACAAAAGAAATAGCCATGAAGCAACTATGACACAAATCAAAAAGTTGACTGGTAGCACCGACAGATATGATCGAAGGCATCCTGGAAACAAGCCTA
TCAAAGATCAGCTTGGATTAAGCTTTCATTCGCATCTTCCTGAACTCCACATATTTCAGACCAAAGGGAAAGTTGGTAATCAAGTTGAGAAGTCTATCAACGATGCTTCCTCAGTTCTAACGTCCCAA
AGAATTTCTTCTAGGCCCAAAATCCATATTTCTAATAACTATGAAAATAATTTCTTCCATTCATCATTACTCACACTAAAACAGGAAGTACACATAAGAGAAAAATCTTTCCAATGTAATGAGAGTGG
CAAAGCCTTTAATTGTAGCTCACTCTTAAGGAAACATCAGATAATCTATTTAGGAGGGAAACAATATAAATGTGATGTATGTGGCAAGGTCTTTAATCAGAAGCGATACCTTGCATGCCATCATAGAT
GTCACACTGGTGAGAAACCTTACAAGTGTAATGAATGTGGCAAGGTTTTTAATCAACAATCAAACCTTGCAAGTCATCATAGACTTCATACTGGAGAGAAACCTTACAAATGTGAAGAATGTGACAAA
GTTTTTAGTCGCAAATCAAATCTTGAAAGACATAGGAGAATTCATACTGGAGAGAAACCATACAAATGTAAGGTTTGTGAAAAGGCTTTCAGGCGTGATTCACACCTCACACAACACACTAGAATTCA
CACTGGAGAGAAACCTTACAAGTGTAATGAGTGTGGCAAAGCCTTTAGTGGGCAGTCAACACTTATTCACCATCAAGCAATCCATGGTATAGGGAAACTTTATAAATGTAATGATTGTCACAAAGTCT
TCAGTAATGCTACAACCATTGCAAATCATTGGAGAATCCATAATGAAGAGAGATCTTACAAGTGTAATAAATGTGGCAAATTTTTTAGACGTCGTTCATATCTCGTAGTTCATTGGCGAACTCATACT
GGAGAGAAACCTTACAAGTGTAATGAGTGTGGCAAGACCTTCCATCACAATTCAGCCCTTGTAATTCATAAGGCAATTCATACTGGAGAGAAACCTTACAAGTGTAATGAGTGTGGCAAGACCTTCCG
TCACAATTCAGCCCTTGTAATTCATAAGGCAATTCATACTGGAGAGAAACCTTACAAGTGTAATGAATGTGGCAAGGTTTTTAATCAACAAGCAACCCTTGCACGTCATCATAGACTTCATACTGGAG
AGAAACCTTACAAATGTGAAGAATGTGACACAGTTTTCAGTCGCAAATCACACCATGAAACACATAAGAGAATTCATACTGGAGAGAAACCTTACAAATGTGATGATTTTGACGAGGCCTTCAGTCAA
GCTTCATCTTATGCAAAACAAAGGAGAATTCATATGGGAGAGAAACATCACAAGTGTGATGATTGTGGCAAAGCCTTTACTTCACATTCACATCGCATTAGACATCAGAGAATCCATACCGGACAGAA
ATCTTACAAATGTCATAAGCGTGGCAAGGTCTTCAGTTAGAGGTCACTCCTTGCAAAACATCAGAAAATTCATTCCTGAGATAATTGTTCCAAATGCAATGAGTATAGCAAACCATCAAGCATTAATT
GACATTAGAGTCAATTCAGCATTGACTTGAGTTTCAGTTGACTTGACATTGAGTTCAAGCATTAATTGACATTAAAGTGTTTACGTTAAGAGGATTGGGCTGGGCAGGGTGGCTTATACCTGTAATCC
CAGCACTGTGGGAGGTCAAGACGGATAGATCACTTGAGGTCAGGAGTTTGAGACCATCCTGGCCAAAAGACGTGAGCCACTTTTCCTAGCCTGTTTTTTGTTTCTGATAGGGATTTTTATGGGTATTG
TGTTGAATCTAAATCACATTGGGTTATATAATCATTTAACAATATTAATCTTTCCAATCCATCAATATGGGTCATATCTCTATTTATATAAGTTTTTAATCATTTTGATCAATGTTTGTAGATTTCAA
GGTACAAACTTCTCACCTTTTTACGTTTATTCCTAAATATTTCTTACTGTAAGTTCTCTAGCAAATGGAAGTGTTTTCTTAATTTTCTTTTAACATTGTTTATTGTTAATGTATGGAAATTTAACTAA
TTTTTGGTACTGATATTGTATTCTGCAAATACACTGTGTTTATTAGCTTCAGTAGTATTTTAGTTGACTCTGTGATTTTCTACACAGCAGATCATGTCATCTACAAACAAATACAATTTTACTTCTTT
CTTTCTGAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_047448072 ⟹ XP_047304028

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	31,981,750 - 31,991,723 (+)	NCBI

RefSeq Acc Id:

XM_047448073 ⟹ XP_047304029

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	31,981,750 - 31,991,632 (+)	NCBI

RefSeq Acc Id:

XM_047448074 ⟹ XP_047304030

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	31,981,750 - 31,991,723 (+)	NCBI

RefSeq Acc Id:

XM_054346427 ⟹ XP_054202402

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	31,984,716 - 31,994,689 (+)	NCBI

RefSeq Acc Id:

XM_054346428 ⟹ XP_054202403

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	31,984,716 - 31,994,601 (+)	NCBI

RefSeq Acc Id:

XM_054346429 ⟹ XP_054202404

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	31,984,716 - 31,994,689 (+)	NCBI

RefSeq Acc Id:

XR_001740138

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	31,985,198 - 32,006,443 (+)	NCBI

Sequence:

show sequence

CATTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCATCTCAAAAAATGTTTTAAAAATACAAA
ATATTGGCTAAACACAAATGCTCAATATAAGGACCATTTCCTTAATTTACCCAGATTGCATAAATCACTTAGAAAAAATTTTAAACGTAAATAGAATGACTGGAAATCTGACAGCCATCACAGACCAT
GTAAAGATTTTGGGAATGAAGCTATGCATGATTGGAGCAATAAGATAAACACATTATACCTCTTGAAATAATGGACAGAATCAGTAGTTCCTAGTAGGGAGCTGACTACCCCATCTTCTTCTCCACAT
GGACCTGGAGGGCTGGTCTGGAGTTTCTAGTAGTTGTTTCTGAGGCTCCCTCCTCTAGTTAGAAAGCCTTAGGAGGATGTTCATGGACCAGCAAGTAAGTGAGTGGACATTGACTTCATTGGCCAGAT
GACAGGAATGAAGCTTGGCCACGAATAGAGAGAAAATTATCACAACCAGATCACTCTCTGATATCAACTTGGTCATGTCTGTGTTAGAAACATGTGGTCTGATGTGTTGTACGTCCCAAATAATAATA
ACAATAATAGCTAATGTATATTGAGCACTATGTGCTAGACTCTGCTTTAAGTGTTTTACACATAATAACTCATTAAATCCTCACAACAACCACATGAGGAGATCTACAGTTCTTACTCCCATTTTACA
GGCAGAGGAAACTGAATTGAAGAGAGGTTCAGCAACATCCCCCAAATTCTGGTGGAGCCAGGATTTCAACTTAGGCAATTTGGCTACTGAGCGTGAGTTCTTAGCCACCGTATTATACCACTTGCTTT
GCAATGAATCCAGTTTCATTTCCTCTACTTAATGAAACTGCAGAAAGCACAGCTCAGTGCCTGGAATTCCATTTCCTGTTATATTTTTATGCATTTAGGAATTGATCCTCTCATTACCACTCTGAGAG
AAGCAGTACAGGTGTTTGGGCCTCTAGCACCCAGCCACAGGGCCTGAACACAATCATACTCAATACATGTTTATTGCATGATAAATGAAGCCTAATTTTACTGAGGAAGAAACAGAAACTCAAAGAGG
AGGAGTTGATTCTGAACCAAGGCCTTCTGACTCCAAGTCCAGTGTTCTTGCTGCCTGAACTTCAGCTGTGACGTGTACATGCAACCTTACCATCCAGTGGGAAGAAGAAAATACCAGAATTAAGATGA
AAGGGAAGAAATGAGGAATGGCTTCAGCATCAAAGTATACTCCCCATCAGCATATCTCACCACTGGCGACTCACCCTTTGAATGAAAACCCCTCAGAAAAAATTCCATGTGCTATGATGAATTGCTGT
CCACTCAACCAACCCAAGACCAGCAGGAACAAAGCCTACTCTGAAAAAGCCTACAAAGTTGTGTTCATTGACACATTGCAAAGAGACCACACACCAGGAGAACCATAGGGTATCTCCCCAAACAAGGA
AAAGAAAAGAATTACAGTATGGGGCAAGGGGAGGAATGGAATTTAAGTGAAATGTATTTTGACAGACTCAAAGCAAGATAGGTCTAAATGTAAAGGTATTATTTTAAGTCCTGGACTATGAAGCAGAC
CCAGGAACCTGTTTGCTGGGAAGCAATAAGATTATTATCCATAGCTGTGGAATACTGTGTCCAAAAACCCCTCCTCCAAAGCTCTGTACCTAGGGTTTGAATCAAGGCTTCTTCTCTCTTGGTGACTT
AGATCCTCCAGGCAAGGGTGAGATGTTTCACTCTAACATCATTTCAAACAGCAATGTTTCTGATAGTCTAAGATTTTAGAGAAAAAAGGTTTCTCAGTGAGTCAGAAGGCACTACTCACTCCAAGAAG
GGGGTTGTTGTGACCCTTTACCACTACAGTGTGCCCCTTGGGAGAAATACTATTTATTGTTAACTTTGAATCTGCTTTTATCTTTTATTCCAGCCTGATGAATGGCCAGGCAGATTTTAACAGTCCAA
GCTAATTTTTACTTTCTCTTGTCTCAATGGGGGTGACAGACAATCAGGTCATTACAACACAGTGGGAGAAGCAACTATGATGAGGGTTTAATTTAGACTTCATTTAGGTCAGGGAAGACTGTCTGCAG
GAGGCAGACCTCCCAGCTGGGAAAAGCAGAAGCTGGCCGAACGAAAGTGGGAAGGAGGAGTGTTACAGCACAGTGAGGACTTGGGCAGAGGCACCAGAGTGGGGCAGAGGGTGGTAAATTGGAGGAAT
CACAAGTGTCATTGAAGGCAAATCAACGGAATGTCTAGAATGCTTTGGAGGACTGCGTAACACTTACATCAGAACTTAGACCAAACTCTCCTCTGGCTAAGGTTAGAAAGCACAGGTCACTGGGAGTA
TGTGTTCTCTGTTCAGGGGAGAGTCATTAGCGTGGTCTTCCTATGCATATACACATGAAAGGCAAGTAGCCCCCAGAGGGGAAGTGCTAAGGGGGAGTTCCCCCGAGGTTTCCTAAGGCACCTGGTTT
GCAAAGCTGATCCCTGTGTGGAAAGTGGAGCCATTTGTAGACTTGCCCTGAACCATCCCATCCTGTTTCCTGAGGACATTTAGGGAACCAGGCTAGCCTTTAACCAATGCTGAGTTTCAGGAAAGGAC
AAGGACAACCAAGAAATAAAACCACCATGAAGAAACAGGGTGTTTCTGAGAACTGAATATACCAGTGGGTGGTATCATTCAAGGTCCTGGGAGGGAACAGACTGCACAGTGAAACAGGATAATCCTCT
TTCTCGTCTCTTCACTGGCCGAAACCAATCAGGAACAAAGGGCAAGGATTTAATTGGTCCAGGTGGACCTGGGCATCGGAGGTCATGTAGCTCTGCAGGGCACTGCAGTGTGTGGTCAGCACTGAGGG
CACCTCTCTCTGAGAGCTGCCAAGGCTGTCCCTGGAGGTCATCCTCCAGGACAGAGAGCAAGGTGGAAAAGGGAGAACAGTGGATTTGGAGGGACAAAGTAGAAAGTTCTAGAACACGGGCTAATACT
AAGGGCTCTTTTGGACTTGTTCACCCTGGCACAGAGGTTTTTCTCTGCAAAACAACAGCTGGATTTGGGAAAGTGAGATAAAAGGAGTTGTCACTTATAGCACAGCAGGGAACAGCAGACCCTAGCAC
TGTGGACCTGGTGTCTTCAACAAACTGCCACTTTGGAGACAAGCAGTAGAAAGAATTTTAAATTATTGAACTTACTAGTTTTAACTTATATTATTTTAAATGATTTCTTATTTAAAAAATTAACGAGT
GTCCATGTTGGCACCCTTTGTTAGAGAAGCAGATCCTGTTAGAGTGGTGACAGCCAAGTCTGGAGCCCTAAGCAAGTCTGGAAGGACATGAGTGTCAGGTGGAGACTTTATCCTGAGGGCAGTGTGGA
CCTGGAGGGCCTCCAGCAGGGAGCAGCATGTGGTACTGGCTGCTTTTGCTGGATTATGCTGTGATAGGCAAGCCCCTGCCCATCCCTTACATTACCAGGAAGGATTGCATATTAATTCTGTTGTCACC
TGACTCCCTTGCCCAGATGGGGAAGACAACTGTTAAGCACTAGAAGAGAAGACAAGAAAGGGGAGTCAGAACACAGGGACAAAAAACAGTACTTGCTTTTCAATTTTGAGCCTTCAAGATATCGGCTG
GAGAACTAGAAAATCTTGTTTCCAGGCATCACATTCTTCGGTTCCTCTGCATTTTTCTAAGCTTTGGAGGAATGTATAAACTGGTTTCCAAAAATGTTCTGAGTTTTCTTTCAACAAAACTATTGAAC
ACCTGCTATGTGTCAGGTACCAAGAGAACAACAGAGAAGAAAACATGGGCTGCCTGACAGCCTTGCAGAGCGACAGACACATGCGCAGTTATTTGCAGGTGTATGGCTTAGCCTCTAAAACAATGCAG
GCCATGTTTTAGACCAAAGAAAAGGATAGCTAGAATTTTTACAGGTGCATAAAATTAAGTAAATTATAGTCCTTATTTCATGGTGCTTATTGTCATCAGCCTGTTTTATTTTTTGCAATTCAATTCCC
ACTTATGTTTCTCCCCATAGGCACCCACTTTGATGGACTTAATAAGTATCCTTGGATAGGATGGCATCTTTATAAAATCATACAGAAGTGGTATCACACCGTAGATCTTAATCTGCCGCTTCTTTCAC
TCAACACTTTTTTTTATTATTTTACTTTAAGTTCTGGTGTACATGTGCAGAACGTTCA

hide sequence

RefSeq Acc Id:

XR_007073404

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	31,988,164 - 32,009,928 (+)	NCBI

RefSeq Acc Id:

XR_007073405

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	3	31,997,897 - 32,009,928 (+)	NCBI

RefSeq Acc Id:

XR_007095674

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	3	31,994,940 - 32,006,443 (+)	NCBI


Protein RefSeqs	NP_001131146	(Get FASTA)	NCBI Sequence Viewer
	XP_047304028	(Get FASTA)	NCBI Sequence Viewer
	XP_047304029	(Get FASTA)	NCBI Sequence Viewer
	XP_047304030	(Get FASTA)	NCBI Sequence Viewer
	XP_054202402	(Get FASTA)	NCBI Sequence Viewer
	XP_054202403	(Get FASTA)	NCBI Sequence Viewer
	XP_054202404	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	A6NHJ4	(Get FASTA)	NCBI Sequence Viewer
	BAG57365	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000373274
	ENSP00000373274.3

RefSeq Acc Id:

NP_001131146 ⟸ NM_001137674

- UniProtKB:

B4DFA4 (UniProtKB/Swiss-Prot), A6NHJ4 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MLREEAAQKRKEKEPGMALPQGHLTFRDVAIEFSLEEWKCLDPTQRALYRAMMLENYRNLHSVDISSKCMMKKFSSTAQGNTEVDTGTLERHESHHIGDFCFQKIGKDIHDFEFQWQEDKRNSHEATM
TQIKKLTGSTDRYDRRHPGNKPIKDQLGLSFHSHLPELHIFQTKGKVGNQVEKSINDASSVLTSQRISSRPKIHISNNYENNFFHSSLLTLKQEVHIREKSFQCNESGKAFNCSSLLRKHQIIYLGGK
QYKCDVCGKVFNQKRYLACHHRCHTGEKPYKCNECGKVFNQQSNLASHHRLHTGEKPYKCEECDKVFSRKSNLERHRRIHTGEKPYKCKVCEKAFRRDSHLTQHTRIHTGEKPYKCNECGKAFSGQST
LIHHQAIHGIGKLYKCNDCHKVFSNATTIANHWRIHNEERSYKCNKCGKFFRRRSYLVVHWRTHTGEKPYKCNECGKTFHHNSALVIHKAIHTGEKPYKCNECGKTFRHNSALVIHKAIHTGEKPYKC
NECGKVFNQQATLARHHRLHTGEKPYKCEECDTVFSRKSHHETHKRIHTGEKPYKCDDFDEAFSQASSYAKQRRIHMGEKHHKCDDCGKAFTSHSHRIRHQRIHTGQKSYKCHKRGKVFS

hide sequence

Ensembl Acc Id:

ENSP00000373274 ⟸ ENST00000360311

RefSeq Acc Id:	XP_047304028 ⟸ XM_047448072
- Peptide Label:	isoform X1
- UniProtKB:	B4DFA4 (UniProtKB/Swiss-Prot), A6NHJ4 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_047304030 ⟸ XM_047448074
- Peptide Label:	isoform X1
- UniProtKB:	B4DFA4 (UniProtKB/Swiss-Prot), A6NHJ4 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_047304029 ⟸ XM_047448073
- Peptide Label:	isoform X1
- UniProtKB:	B4DFA4 (UniProtKB/Swiss-Prot), A6NHJ4 (UniProtKB/Swiss-Prot)

Protein Domains

KRAB

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A6NHJ4-F1-model_v2	AlphaFold	A6NHJ4	1-632	view protein structure

RGD ID:

6801985

Promoter ID:

HG_KWN:44220

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, Lymphoblastoid

Transcripts:

NM_001137674, OTTHUMT00000341958

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	3	31,997,134 - 31,997,634 (+)	MPROMDB

Database	Acc Id	Source(s)
COSMIC	ZNF860	COSMIC
Ensembl Genes	ENSG00000197385	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000360311	ENTREZGENE
	ENST00000360311.5	UniProtKB/Swiss-Prot
Gene3D-CATH	6.10.140.140	UniProtKB/Swiss-Prot
	Classic Zinc Finger	UniProtKB/Swiss-Prot
GTEx	ENSG00000197385	GTEx
HGNC ID	HGNC:34513	ENTREZGENE
Human Proteome Map	ZNF860	Human Proteome Map
InterPro	KRAB	UniProtKB/Swiss-Prot
	KRAB_dom_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_type	UniProtKB/Swiss-Prot
KEGG Report	hsa:344787	UniProtKB/Swiss-Prot
NCBI Gene	ZNF860	ENTREZGENE
PANTHER	C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED	UniProtKB/Swiss-Prot
	KRUEPPEL-LIKE TRANSCRIPTION FACTOR	UniProtKB/Swiss-Prot
Pfam	KRAB	UniProtKB/Swiss-Prot
	zf-C2H2	UniProtKB/Swiss-Prot
PharmGKB	PA164727773	PharmGKB
PROSITE	KRAB	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot
SMART	KRAB	UniProtKB/Swiss-Prot
	ZnF_C2H2	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF109640	UniProtKB/Swiss-Prot
	SSF57667	UniProtKB/Swiss-Prot
UniProt	A6NHJ4	ENTREZGENE
	B4DFA4	ENTREZGENE
	ZN860_HUMAN	UniProtKB/Swiss-Prot
UniProt Secondary	B4DFA4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-03-23	ZNF860	zinc finger protein 860	LOC124906225	uncharacterized LOC124906225	Data merged from RGD:151669587	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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