Zfp141 (zinc finger protein 141) - Rat Genome Database

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Gene: Zfp141 (zinc finger protein 141) Mus musculus
Analyze
Symbol: Zfp141
Name: zinc finger protein 141
RGD ID: 1613919
MGI Page MGI
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39742,122,810 - 42,155,171 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl742,122,810 - 42,155,164 (-)EnsemblGRCm39 Ensembl
GRCm38742,473,386 - 42,505,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl742,473,386 - 42,505,740 (-)EnsemblGRCm38mm10GRCm38
MGSCv37749,728,756 - 49,761,123 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36742,246,534 - 42,278,906 (-)NCBIMGSCv36mm8
Celera737,155,658 - 37,187,722 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zfp141Mouse2-palmitoylglycerol increases expressionISOZNF502 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of ZNF502 mRNACTDPMID:37199045
Zfp141Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of ZFP141 mRNACTDPMID:39298647
Zfp141Mouse4,4'-sulfonyldiphenol affects methylationISOZNF502 (Homo sapiens)6480464bisphenol S affects the methylation of ZNF502 geneCTDPMID:31601247
Zfp141Mouseantirheumatic drug increases expressionISOZNF502 (Homo sapiens)6480464Antirheumatic Agents results in increased expression of ZNF502 mRNACTDPMID:24449571
Zfp141Mousebenzo[a]pyrene affects methylationISOZNF502 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of ZNF502 5' UTR and Benzo(a)pyrene affects the methylation of ZNF502 promoterCTDPMID:27901495
Zfp141Mousebenzo[a]pyrene decreases methylationISOZNF502 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of ZNF502 exonCTDPMID:27901495
Zfp141Mousebenzo[a]pyrene increases methylationISOZNF502 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of ZNF502 3' UTRCTDPMID:27901495
Zfp141Mousebeta-lapachone increases expressionISOZNF502 (Homo sapiens)6480464beta-lapachone results in increased expression of ZNF502 mRNACTDPMID:38218311
Zfp141Mousebis(2-ethylhexyl) phthalate multiple interactionsISOZNF502 (Homo sapiens)6480464[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of ZNF502 geneCTDPMID:33872906
Zfp141Mousebisphenol A affects expressionISOZfp502 (Rattus norvegicus)6480464bisphenol A affects the expression of ZFP141 mRNACTDPMID:30816183
Zfp141Mousecaffeine decreases phosphorylationISOZNF502 (Homo sapiens)6480464Caffeine results in decreased phosphorylation of ZNF502 proteinCTDPMID:35688186
Zfp141Mousechlorpyrifos decreases expressionEXP 6480464Chlorpyrifos results in decreased expression of ZFP141 mRNACTDPMID:37019170
Zfp141Mouseclothianidin increases expressionISOZNF502 (Homo sapiens)6480464clothianidin results in increased expression of ZNF502 mRNACTDPMID:31626844
Zfp141Mousefolic acid decreases expressionISOZNF502 (Homo sapiens)6480464Folic Acid results in decreased expression of ZNF502 mRNACTDPMID:21867686
Zfp141Mousemono(2-ethylhexyl) phthalate multiple interactionsISOZNF502 (Homo sapiens)6480464[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in increased methylation of ZNF502 geneCTDPMID:33872906
Zfp141Mouseparacetamol increases expressionISOZNF502 (Homo sapiens)6480464Acetaminophen results in increased expression of ZNF502 mRNACTDPMID:26690555
Zfp141Mousepotassium chromate decreases expressionISOZNF502 (Homo sapiens)6480464potassium chromate(VI) results in decreased expression of ZNF502 mRNACTDPMID:22714537
Zfp141Mousequercitrin increases expressionISOZNF502 (Homo sapiens)6480464quercitrin results in increased expression of ZNF502 mRNACTDPMID:25193878
Zfp141Mousesodium arsenite increases expressionISOZNF502 (Homo sapiens)6480464sodium arsenite results in increased expression of ZNF502 mRNACTDPMID:38568856
Zfp141Mousetetrachloromethane increases expressionISOZfp502 (Rattus norvegicus)6480464Carbon Tetrachloride results in increased expression of ZFP141 mRNACTDPMID:31150632

1 to 20 of 21 rows

Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zfp141Mousenucleus is_active_inIBAPANTHER:PTN001225435 more ...2290270 GO_CentralGO_REF:0000033
Zfp141Mousenucleus located_inISOZNF502 (Homo sapiens)9068941 PMID:25556234AgBasePMID:25556234

Molecular Function

  

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Zfp141Mouseabnormal skin pigmentation  IAGP 5509061 MGIPMID:12904583

#
Reference Title
Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693  
PMID:21267068   PMID:21873635  



Zfp141
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39742,122,810 - 42,155,171 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl742,122,810 - 42,155,164 (-)EnsemblGRCm39 Ensembl
GRCm38742,473,386 - 42,505,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl742,473,386 - 42,505,740 (-)EnsemblGRCm38mm10GRCm38
MGSCv37749,728,756 - 49,761,123 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36742,246,534 - 42,278,906 (-)NCBIMGSCv36mm8
Celera737,155,658 - 37,187,722 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
ZNF502
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38344,712,660 - 44,723,831 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl344,712,643 - 44,723,831 (+)EnsemblGRCh38hg38GRCh38
GRCh37344,754,152 - 44,765,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36344,729,142 - 44,740,327 (+)NCBINCBI36Build 36hg18NCBI36
Build 34344,729,141 - 44,740,325NCBI
Celera344,692,121 - 44,703,310 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef344,798,324 - 44,809,514 (+)NCBIHuRef
CHM1_1344,704,177 - 44,715,366 (+)NCBICHM1_1
T2T-CHM13v2.0344,728,342 - 44,739,513 (+)NCBIT2T-CHM13v2.0
Zfp502
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,712,974 - 30,737,956 (+)NCBIGRCr8
mRatBN7.2128,884,390 - 28,908,726 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.0131,494,043 - 31,519,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0132,911,255 - 32,945,182 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera127,536,231 - 27,561,215 (+)NCBICelera
Cytogenetic Map1p11NCBI
ZNF502
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2244,664,637 - 44,676,448 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1344,669,390 - 44,680,891 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0344,607,484 - 44,618,977 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1345,665,147 - 45,676,361 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl345,665,147 - 45,676,361 (+)Ensemblpanpan1.1panPan2
ZNF501
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12043,542,093 - 43,553,933 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2043,456,331 - 43,465,881 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,025,958 - 44,035,304 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,026,167 - 44,033,111 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12043,264,192 - 43,273,724 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02043,672,118 - 43,681,447 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02043,949,168 - 43,958,507 (-)NCBIUU_Cfam_GSD_1.0
Znf502
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118198,594,806 - 198,604,665 (-)NCBIHiC_Itri_2
ZNF502
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,185,332 - 6,197,057 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,193,461 - 6,197,642 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041160,975,513 - 160,987,621 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Zfp141
2131 total Variants

Predicted Target Of
Summary Value
Count of predictions:1081
Count of miRNA genes:595
Interacting mature miRNAs:728
Transcripts:ENSMUST00000173439, ENSMUST00000173489, ENSMUST00000174407, ENSMUST00000174489
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse

1 to 10 of 46 rows





1 to 16 of 16 rows
RefSeq Transcripts NM_001309388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001309389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001421555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY064292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF727770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN459213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 16 of 16 rows

Ensembl Acc Id: ENSMUST00000173439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl742,137,911 - 42,155,149 (-)Ensembl
GRCm38.p6 Ensembl742,488,487 - 42,505,725 (-)Ensembl
Ensembl Acc Id: ENSMUST00000173489   ⟹   ENSMUSP00000145574
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl742,126,609 - 42,155,164 (-)Ensembl
GRCm38.p6 Ensembl742,477,185 - 42,505,740 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174407   ⟹   ENSMUSP00000133899
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl742,122,810 - 42,155,150 (-)Ensembl
GRCm38.p6 Ensembl742,473,386 - 42,505,726 (-)Ensembl
Ensembl Acc Id: ENSMUST00000174489
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl742,125,834 - 42,126,787 (-)Ensembl
GRCm38.p6 Ensembl742,476,410 - 42,477,363 (-)Ensembl
RefSeq Acc Id: NM_001309388   ⟹   NP_001296317
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
GRCm38742,473,386 - 42,505,753 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001309389   ⟹   NP_001296318
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
GRCm38742,473,386 - 42,505,753 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001421545   ⟹   NP_001408474
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
RefSeq Acc Id: NM_001421546   ⟹   NP_001408475
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
RefSeq Acc Id: NM_001421548   ⟹   NP_001408477
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
RefSeq Acc Id: NM_001421550   ⟹   NP_001408479
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
RefSeq Acc Id: NM_001421553   ⟹   NP_001408482
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
RefSeq Acc Id: NM_001421555   ⟹   NP_001408484
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39742,122,810 - 42,155,171 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_001296318   ⟸   NM_001309389
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: NP_001296317   ⟸   NM_001309388
- Peptide Label: isoform 1
- UniProtKB: G3UY09 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000133899   ⟸   ENSMUST00000174407
Ensembl Acc Id: ENSMUSP00000145574   ⟸   ENSMUST00000173489
RefSeq Acc Id: NP_001408479   ⟸   NM_001421550
- Peptide Label: isoform 4
C2H2-type   KRAB

Name Modeler Protein Id AA Range Protein Structure
AF-G3UY09-F1-model_v2 AlphaFold G3UY09 1-685 view protein structure

RGD ID:8663737
Promoter ID:EPDNEW_M9900
Type:initiation region
Name:Zfp141_1
Description:Mus musculus zinc finger protein 141 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38742,505,731 - 42,505,791EPDNEW
RGD ID:6840706
Promoter ID:MM_KWN:50149
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   ES_Cell,   Liver,   MEF_B6
Transcripts:BC063263_BC063263
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36749,760,836 - 49,761,336 (-)MPROMDB


1 to 31 of 31 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000092416 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000173489.3 UniProtKB/TrEMBL
  ENSMUST00000174407 ENTREZGENE
  ENSMUST00000174407.3 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro C2H2-ZF_domain UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Krueppel_C2H2_ZnF UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:434178 UniProtKB/TrEMBL
MGD MGI:3584269 ENTREZGENE
NCBI Gene 434178 ENTREZGENE
PANTHER FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED UniProtKB/TrEMBL
  GENE, 19965-RELATED UniProtKB/TrEMBL
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 993-RELATED UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp141 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0U1RNI1_MOUSE UniProtKB/TrEMBL
  G3UY09 ENTREZGENE, UniProtKB/TrEMBL
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-02 Zfp141  zinc finger protein 141  BC063263  cDNA sequence BC063263  Symbol and/or name change 5135510 APPROVED