Zfp616 (zinc finger protein 616) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Zfp616 (zinc finger protein 616) Mus musculus
Analyze
No known orthologs.
Symbol: Zfp616
Name: zinc finger protein 616
RGD ID: 1621230
MGI Page MGI
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cellular response to zinc ion; regulation of DNA-templated transcription; and ribosome biogenesis.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Gm12330; KRAB box containing protein; novel KRAB box containing protein; RP23-221M24.3
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,951,723 - 73,978,127 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,960,781 - 73,978,118 (+)EnsemblGRCm39 Ensembl
GRCm381174,060,897 - 74,087,301 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,069,955 - 74,087,292 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,874,399 - 73,900,803 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,660,381 - 74,686,992 (+)NCBIMGSCv36mm8
MGSCv361173,877,092 - 73,903,492 (+)NCBIMGSCv36mm8
Celera1181,603,734 - 81,620,687 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
troglitazone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mouse MP Annotation Import Pipeline RGD automated import pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21267068   PMID:21677750   PMID:21873635   PMID:27626380   PMID:30973865   PMID:38355793  


Genomics

Variants

.
Variants in Zfp616
1 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1205
Count of miRNA genes:506
Interacting mature miRNAs:568
Transcripts:ENSMUST00000074813, ENSMUST00000108463, ENSMUST00000116546, ENSMUST00000137407, ENSMUST00000178159
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117220979684731462Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117373754182069425Mouse

Markers in Region
Olfr399  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,053,976 - 74,054,524UniSTSGRCm38
Celera1181,587,364 - 81,587,912UniSTS
Cytogenetic Map11B4UniSTS
cM Map1145.73UniSTS
UniSTS:485204  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,906,552 - 73,907,490UniSTSGRCm38
MGSCv371173,720,054 - 73,720,992UniSTSGRCm37
Celera1181,438,296 - 81,439,234UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:485205  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,776,387 - 73,777,325UniSTSGRCm38
MGSCv371173,589,889 - 73,590,827UniSTSGRCm37
Celera1181,307,776 - 81,308,714UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:489326  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,786,940 - 73,787,875UniSTSGRCm38
MGSCv371173,600,442 - 73,601,377UniSTSGRCm37
Celera1181,315,435 - 81,316,370UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:489490  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,044,325 - 74,045,272UniSTSGRCm38
MGSCv371173,857,827 - 73,858,774UniSTSGRCm37
Celera1181,577,694 - 81,578,641UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:489491  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,887,438 - 73,888,370UniSTSGRCm38
MGSCv371173,700,940 - 73,701,872UniSTSGRCm37
Celera1181,419,003 - 81,419,935UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:491694  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,983,572 - 73,984,626UniSTSGRCm38
MGSCv371173,797,074 - 73,798,128UniSTSGRCm37
Celera1181,517,025 - 81,518,079UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:491761  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,053,776 - 74,054,778UniSTSGRCm38
MGSCv371173,867,278 - 73,868,280UniSTSGRCm37
Celera1181,587,164 - 81,588,166UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:492725  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,847,085 - 73,848,151UniSTSGRCm38
MGSCv371173,660,587 - 73,661,653UniSTSGRCm37
Celera1181,379,737 - 81,380,803UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:494373  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,887,340 - 73,888,405UniSTSGRCm38
MGSCv371173,700,842 - 73,701,907UniSTSGRCm37
Celera1181,418,905 - 81,419,970UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:494973  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,814,047 - 73,815,139UniSTSGRCm38
MGSCv371173,627,549 - 73,628,641UniSTSGRCm37
Celera1181,342,572 - 81,343,664UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:495339  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,964,530 - 73,965,620UniSTSGRCm38
MGSCv371173,778,032 - 73,779,122UniSTSGRCm37
Celera1181,497,983 - 81,499,073UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:495591  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,786,842 - 73,787,963UniSTSGRCm38
MGSCv371173,600,344 - 73,601,465UniSTSGRCm37
Celera1181,315,337 - 81,316,458UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:495660  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,906,469 - 73,907,584UniSTSGRCm38
MGSCv371173,719,971 - 73,721,086UniSTSGRCm37
Celera1181,438,213 - 81,439,328UniSTS
Cytogenetic Map11B4UniSTS
UniSTS:495661  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381173,776,289 - 73,777,390UniSTSGRCm38
MGSCv371173,589,791 - 73,590,892UniSTSGRCm37
Celera1181,307,678 - 81,308,779UniSTS
Cytogenetic Map11B4UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000074813   ⟹   ENSMUSP00000074365
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,960,781 - 73,978,118 (+)Ensembl
GRCm38.p6 Ensembl1174,069,955 - 74,087,292 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108463   ⟹   ENSMUSP00000104103
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,960,781 - 73,974,916 (+)Ensembl
GRCm38.p6 Ensembl1174,069,955 - 74,084,090 (+)Ensembl
Ensembl Acc Id: ENSMUST00000116546   ⟹   ENSMUSP00000112245
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,961,011 - 73,973,865 (+)Ensembl
GRCm38.p6 Ensembl1174,070,185 - 74,083,039 (+)Ensembl
Ensembl Acc Id: ENSMUST00000137407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,960,991 - 73,974,137 (+)Ensembl
GRCm38.p6 Ensembl1174,070,165 - 74,083,311 (+)Ensembl
Ensembl Acc Id: ENSMUST00000178159   ⟹   ENSMUSP00000136549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1173,973,733 - 73,976,696 (+)Ensembl
GRCm38.p6 Ensembl1174,082,907 - 74,085,870 (+)Ensembl
RefSeq Acc Id: NM_001177570   ⟹   NP_001171041
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391173,951,723 - 73,978,127 (+)NCBI
GRCm381174,060,897 - 74,087,301 (+)ENTREZGENE
MGSCv371173,874,399 - 73,900,803 (+)RGD
Celera1181,603,734 - 81,620,687 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001171041 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000074365.6
  ENSMUSP00000104103.2
  ENSMUSP00000112245.3
  ENSMUSP00000136549
  ENSMUSP00000136549.2
RefSeq Acc Id: NP_001171041   ⟸   NM_001177570
- UniProtKB: J3QN14 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000136549   ⟸   ENSMUST00000178159
Ensembl Acc Id: ENSMUSP00000104103   ⟸   ENSMUST00000108463
Ensembl Acc Id: ENSMUSP00000074365   ⟸   ENSMUST00000074813
Ensembl Acc Id: ENSMUSP00000112245   ⟸   ENSMUST00000116546
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-J3QN14-F1-model_v2 AlphaFold J3QN14 1-987 view protein structure

Promoters
RGD ID:8675598
Promoter ID:EPDNEW_M15777
Type:single initiation site
Name:Zfp616_1
Description:Mus musculus zinc finger protein 616 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381174,065,712 - 74,065,772EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3650906 AgrOrtholog
Ensembl Genes ENSMUSG00000069476 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074813.12 UniProtKB/TrEMBL
  ENSMUST00000108463.8 UniProtKB/TrEMBL
  ENSMUST00000116546.3 UniProtKB/TrEMBL
  ENSMUST00000178159 ENTREZGENE
  ENSMUST00000178159.2 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Krueppel_C2H2_ZnF UniProtKB/TrEMBL
  Znf_C2H2-type UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report mmu:327963 UniProtKB/TrEMBL
MGD MGI:3650906 ENTREZGENE
NCBI Gene 327963 ENTREZGENE
PANTHER C2H2-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  KRAB DOMAIN-CONTAINING PROTEIN 5 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 993-RELATED UniProtKB/TrEMBL
  ZNF44 PROTEIN UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp616 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A7DTG8_MOUSE UniProtKB/TrEMBL
  J3QN14 ENTREZGENE, UniProtKB/TrEMBL
  Q5SVV3_MOUSE UniProtKB/TrEMBL