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Gene: Igf2 (insulin-like growth factor 2) Mus musculus
Symbol: Igf2
Name: insulin-like growth factor 2
Description: Exhibits insulin-like growth factor receptor binding activity; protein serine/threonine kinase activator activity; and receptor ligand activity. Involved in several processes, including embryonic placenta development; regulation of cellular macromolecule biosynthetic process; and regulation of protein modification process. Localizes to extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and sensory organ. Used to study type 1 diabetes mellitus 2. Human ortholog(s) of this gene implicated in Silver-Russell syndrome; choriocarcinoma; hepatocellular carcinoma; and rheumatoid arthritis. Orthologous to human IGF2 (insulin like growth factor 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL033362; Igf-2; Igf-II; insulin-like growth factor II; M6pr; Mpr; multiplication-stimulating polypeptide; Peg2
Homo sapiens (human) : IGF2 (insulin like growth factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Igf2 (insulin-like growth factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2 (insulin like growth factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2 (insulin like growth factor 2)
Canis lupus familiaris (dog) : IGF2 (insulin like growth factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2 (insulin like growth factor 2)
Sus scrofa (pig) : IGF2 (insulin like growth factor 2)
Chlorocebus sabaeus (African green monkey) : IGF2 (insulin like growth factor 2)
Heterocephalus glaber (naked mole-rat) : Igf2 (insulin like growth factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl7142,650,766 - 142,666,816 (-)EnsemblGRCm38mm10GRCm38
GRCm387142,650,768 - 142,666,816 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377149,836,673 - 149,846,940 (-)NCBIGRCm37mm9NCBIm37
MGSCv367142,460,158 - 142,468,879 (-)NCBImm8
Celera7142,407,105 - 142,417,364 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Igf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10770
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.