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Gene: Igf2 (insulin-like growth factor 2) Mus musculus
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Symbol: Igf2
Name: insulin-like growth factor 2
Description: Exhibits insulin-like growth factor receptor binding activity; protein serine/threonine kinase activator activity; and receptor ligand activity. Involved in several processes, including embryonic placenta development; regulation of cellular macromolecule biosynthetic process; and regulation of protein modification process. Localizes to extracellular space. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and sensory organ. Used to study type 1 diabetes mellitus 2. Human ortholog(s) of this gene implicated in Silver-Russell syndrome; choriocarcinoma; hepatocellular carcinoma; and rheumatoid arthritis. Orthologous to human IGF2 (insulin like growth factor 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL033362; Igf-2; Igf-II; insulin-like growth factor II; M6pr; Mpr; multiplication-stimulating polypeptide; Peg2
Orthologs:
Homo sapiens (human) : IGF2 (insulin like growth factor 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Igf2 (insulin-like growth factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf2 (insulin like growth factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF2 (insulin like growth factor 2)
Canis lupus familiaris (dog) : IGF2 (insulin like growth factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf2 (insulin like growth factor 2)
Sus scrofa (pig) : IGF2 (insulin like growth factor 2)
Chlorocebus sabaeus (African green monkey) : IGF2 (insulin like growth factor 2)
Heterocephalus glaber (naked mole-rat) : Igf2 (insulin like growth factor 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl7142,650,766 - 142,666,816 (-)EnsemblGRCm38mm10GRCm38
GRCm387142,650,768 - 142,666,816 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377149,836,673 - 149,846,940 (-)NCBIGRCm37mm9NCBIm37
MGSCv367142,460,158 - 142,468,879 (-)NCBImm8
Celera7142,407,105 - 142,417,364 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map787.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Igf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10770
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.