H2-DMa (histocompatibility 2, class II, locus DMa) - Rat Genome Database

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Gene: H2-DMa (histocompatibility 2, class II, locus DMa) Mus musculus
Analyze
Symbol: H2-DMa
Name: histocompatibility 2, class II, locus DMa
RGD ID: 1551725
MGI Page MGI
Description: Predicted to enable MHC class II protein complex binding activity. Involved in positive regulation of germinal center formation and positive regulation of humoral immune response. Acts upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; chaperone cofactor-dependent protein refolding; and positive thymic T cell selection. Located in endosome membrane; lysosomal membrane; and multivesicular body. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human HLA-DMA (major histocompatibility complex, class II, DM alpha); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: class II histocompatibility antigen, M alpha chain; H-2M; H-2Ma; H2-M; H2-M alpha; H2-Ma; histocompatibility 2, class II, locus Ma; MHC class II antigen DMa
RGD Orthologs
Human
Rat
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,338,667 - 34,358,075 (+)NCBIGRCm39mm39
GRCm39 Ensembl1734,338,515 - 34,358,075 (+)Ensembl
GRCm381734,119,693 - 34,139,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,119,541 - 34,139,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,272,616 - 34,275,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,746,082 - 33,749,555 (+)NCBImm8
Celera1736,887,536 - 36,890,397 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
alachlor  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (EXP,ISO)
chloroprene  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
coumarin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diethylstilbestrol  (EXP)
dorsomorphin  (ISO)
doxorubicin  (EXP)
entinostat  (ISO)
fonofos  (ISO)
genistein  (EXP)
hexachlorobenzene  (ISO)
isoprenaline  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
nickel sulfate  (ISO)
omeprazole  (ISO)
ozone  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (ISO)
streptozocin  (ISO)
sulforaphane  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichostatin A  (ISO)
Triptolide  (EXP)
triptonide  (EXP)
tunicamycin  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1711220   PMID:1855816   PMID:1922366   PMID:7584146   PMID:7607704   PMID:7985028   PMID:8575819   PMID:8598040   PMID:8598041   PMID:8613139   PMID:8638109   PMID:8890155  
PMID:9256469   PMID:9285404   PMID:9285405   PMID:9432982   PMID:9492004   PMID:9531264   PMID:9551884   PMID:9551894   PMID:9723702   PMID:9754549   PMID:9768758   PMID:9872742  
PMID:10023773   PMID:10221647   PMID:10349636   PMID:10367901   PMID:10375304   PMID:10395655   PMID:10490950   PMID:10779766   PMID:10843678   PMID:10871872   PMID:10880524   PMID:10922068  
PMID:11027433   PMID:11042159   PMID:11076861   PMID:11086052   PMID:11148202   PMID:11160278   PMID:11160279   PMID:11217851   PMID:11290790   PMID:11359802   PMID:11602620   PMID:11777953  
PMID:11854359   PMID:11937578   PMID:12011450   PMID:12011451   PMID:12466851   PMID:12477932   PMID:12538710   PMID:12629221   PMID:12646641   PMID:12884868   PMID:12889995   PMID:12928379  
PMID:14610273   PMID:14764672   PMID:15034026   PMID:15265882   PMID:15998789   PMID:16141072   PMID:16141073   PMID:16272301   PMID:16493054   PMID:17114442   PMID:17513752   PMID:18209058  
PMID:18287559   PMID:18464936   PMID:18591414   PMID:18778282   PMID:19342667   PMID:19843939   PMID:20861357   PMID:21267068   PMID:21641398   PMID:21677750   PMID:21795542   PMID:21873635  
PMID:22623329   PMID:23418596   PMID:24487322   PMID:26195549   PMID:26618355   PMID:28813660   PMID:31996461  


Genomics

Comparative Map Data
H2-DMa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,338,667 - 34,358,075 (+)NCBIGRCm39mm39
GRCm39 Ensembl1734,338,515 - 34,358,075 (+)Ensembl
GRCm381734,119,693 - 34,139,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,119,541 - 34,139,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv371734,272,616 - 34,275,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,746,082 - 33,749,555 (+)NCBImm8
Celera1736,887,536 - 36,890,397 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
HLA-DMA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl632,948,613 - 32,969,094 (-)EnsemblGRCh38hg38GRCh38
GRCh38632,948,618 - 32,953,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37632,916,395 - 32,920,874 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,024,373 - 33,028,831 (-)NCBINCBI36hg18NCBI36
Build 34633,024,373 - 33,028,831NCBI
Celera634,465,294 - 34,469,805 (-)NCBI
Cytogenetic Map6p21.32NCBI
HuRef632,658,920 - 32,663,431 (-)NCBIHuRef
CHM1_1632,917,186 - 32,921,697 (-)NCBICHM1_1
LOC100909593
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,935,501 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,015,055 - 6,018,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Cytogenetic Map20 NCBI
RT1-DMa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2204,707,028 - 4,710,432 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl204,707,028 - 4,710,432 (-)Ensembl
Rnor_6.0203,935,512 - 3,938,915 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,240,975 - 5,244,386 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,302,036 - 7,305,439 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,843,458 - 4,846,861 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1204,843,691 - 4,847,054 (-)NCBI
Celera206,307,688 - 6,311,091 (-)NCBICelera
Cytogenetic Map20p12NCBI
LOC102023843
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,558,911 - 1,562,162 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,558,806 - 1,562,294 (-)NCBIChiLan1.0ChiLan1.0
LOC100968989
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1633,633,497 - 33,639,091 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,634,123 - 33,637,988 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0632,518,060 - 32,537,989 (-)NCBIMhudiblu_PPA_v0panPan3
DLA-DMA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,516,974 - 2,534,085 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,503,325 - 2,533,990 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,598,545 - 2,602,105 (-)NCBI
ROS_Cfam_1.0122,847,916 - 2,865,029 (-)NCBI
UMICH_Zoey_3.1122,516,014 - 2,519,572 (-)NCBI
UNSW_CanFamBas_1.0122,597,566 - 2,601,126 (-)NCBI
UU_Cfam_GSD_1.0122,672,100 - 2,675,661 (-)NCBI
LOC101963772
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,120,076 - 38,124,109 (-)NCBI
SpeTri2.0NW_00493647625,836,163 - 25,840,191 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLA-DMA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,133,214 - 25,138,348 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,133,494 - 25,137,928 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,500,103 - 29,504,572 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q1.1NCBI
MHC-DMA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,142,340 - 39,151,804 (+)NCBI
ChlSab1.1 Ensembl1739,142,395 - 39,146,252 (+)Ensembl
Vero_WHO_p1.0NW_02366604432,737,022 - 32,757,552 (-)NCBI
LOC101700274
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475423,752,352 - 23,765,319 (+)NCBI

Position Markers
H2-DMa  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381734,138,042 - 34,138,443UniSTSGRCm38
MGSCv371734,274,987 - 34,275,388UniSTSGRCm37
Celera1736,889,904 - 36,890,305UniSTS
Cytogenetic Map17B1UniSTS
cM Map1718.56UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172628636340794146Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172749681845311728Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172750432261504322Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172765914543574223Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172831148062311728Mouse
11038694Pas19_mpulmonary adenoma susceptibility 19 (mouse)172949219034535463Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined172982162963821740Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3072257564722705Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3076892947728778Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173184267837333884Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173244145235301060Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173290000053800000Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173360074735939288Mouse
1301759Sles1_msystemic lupus erythmatosus suppressor 1 (mouse)Not determined173400091634956961Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:578
Count of miRNA genes:393
Interacting mature miRNAs:435
Transcripts:ENSMUST00000042121, ENSMUST00000173907
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001360530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF100956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR974422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR974462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU407132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KJ650223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U20311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X62742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000042121   ⟹   ENSMUSP00000037088
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,341,806 - 34,358,075 (+)Ensembl
GRCm38.p6 Ensembl1734,122,832 - 34,139,101 (+)Ensembl
RefSeq Acc Id: ENSMUST00000173907
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,356,002 - 34,357,154 (+)Ensembl
GRCm38.p6 Ensembl1734,137,028 - 34,138,180 (+)Ensembl
RefSeq Acc Id: ENSMUST00000235408
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,341,820 - 34,356,174 (+)Ensembl
GRCm38.p6 Ensembl1734,122,846 - 34,137,200 (+)Ensembl
RefSeq Acc Id: ENSMUST00000235910
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,341,796 - 34,354,579 (+)Ensembl
GRCm38.p6 Ensembl1734,122,822 - 34,135,605 (+)Ensembl
RefSeq Acc Id: ENSMUST00000236322   ⟹   ENSMUSP00000157660
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,354,602 - 34,358,074 (+)Ensembl
GRCm38.p6 Ensembl1734,135,628 - 34,139,100 (+)Ensembl
RefSeq Acc Id: ENSMUST00000236938
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,338,515 - 34,354,386 (+)Ensembl
GRCm38.p6 Ensembl1734,119,541 - 34,135,412 (+)Ensembl
RefSeq Acc Id: ENSMUST00000237402   ⟹   ENSMUSP00000158155
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,354,628 - 34,358,052 (+)Ensembl
GRCm38.p6 Ensembl1734,135,654 - 34,139,078 (+)Ensembl
RefSeq Acc Id: ENSMUST00000237476
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1734,338,562 - 34,354,434 (+)Ensembl
GRCm38.p6 Ensembl1734,119,588 - 34,135,460 (+)Ensembl
RefSeq Acc Id: NM_001360530   ⟹   NP_001347459
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,344,492 - 34,358,075 (+)NCBI
GRCm381734,125,518 - 34,139,101 (+)NCBI
Sequence:
RefSeq Acc Id: NM_010386   ⟹   NP_034516
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,341,806 - 34,358,075 (+)NCBI
GRCm381734,122,832 - 34,139,101 (+)NCBI
MGSCv371734,272,616 - 34,275,480 (+)RGD
Celera1736,874,856 - 36,890,963 (+)NCBI
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523684   ⟹   XP_006523747
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,341,665 - 34,358,057 (+)NCBI
GRCm381734,122,691 - 34,139,083 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317260   ⟹   XP_017172749
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,343,357 - 34,358,057 (+)NCBI
GRCm381734,124,383 - 34,139,083 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030249508   ⟹   XP_030105368
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391734,338,667 - 34,358,057 (+)NCBI
GRCm381734,119,693 - 34,139,083 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001347459 (Get FASTA)   NCBI Sequence Viewer  
  NP_034516 (Get FASTA)   NCBI Sequence Viewer  
  XP_006523747 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172749 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105368 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA86483 (Get FASTA)   NCBI Sequence Viewer  
  AAA86484 (Get FASTA)   NCBI Sequence Viewer  
  AAA86487 (Get FASTA)   NCBI Sequence Viewer  
  AAA91134 (Get FASTA)   NCBI Sequence Viewer  
  AAA91135 (Get FASTA)   NCBI Sequence Viewer  
  AAA91136 (Get FASTA)   NCBI Sequence Viewer  
  AAA91137 (Get FASTA)   NCBI Sequence Viewer  
  AAA91138 (Get FASTA)   NCBI Sequence Viewer  
  AAA98929 (Get FASTA)   NCBI Sequence Viewer  
  AAB60514 (Get FASTA)   NCBI Sequence Viewer  
  AAC69910 (Get FASTA)   NCBI Sequence Viewer  
  AAH01996 (Get FASTA)   NCBI Sequence Viewer  
  AAH49992 (Get FASTA)   NCBI Sequence Viewer  
  AIC84011 (Get FASTA)   NCBI Sequence Viewer  
  BAE27559 (Get FASTA)   NCBI Sequence Viewer  
  BAE35801 (Get FASTA)   NCBI Sequence Viewer  
  BAE41446 (Get FASTA)   NCBI Sequence Viewer  
  CAA44604 (Get FASTA)   NCBI Sequence Viewer  
  CAA62302 (Get FASTA)   NCBI Sequence Viewer  
  CAA62303 (Get FASTA)   NCBI Sequence Viewer  
  CAA62304 (Get FASTA)   NCBI Sequence Viewer  
  CAA62305 (Get FASTA)   NCBI Sequence Viewer  
  CAA62306 (Get FASTA)   NCBI Sequence Viewer  
  CAA62307 (Get FASTA)   NCBI Sequence Viewer  
  CAA62308 (Get FASTA)   NCBI Sequence Viewer  
  CAA62309 (Get FASTA)   NCBI Sequence Viewer  
  CAA62310 (Get FASTA)   NCBI Sequence Viewer  
  CAA62311 (Get FASTA)   NCBI Sequence Viewer  
  CAA62312 (Get FASTA)   NCBI Sequence Viewer  
  CAA62313 (Get FASTA)   NCBI Sequence Viewer  
  CAA62314 (Get FASTA)   NCBI Sequence Viewer  
  CAA62451 (Get FASTA)   NCBI Sequence Viewer  
  EDL10253 (Get FASTA)   NCBI Sequence Viewer  
  P28078 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_034516   ⟸   NM_010386
- Peptide Label: precursor
- UniProtKB: Q31621 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523747   ⟸   XM_006523684
- Peptide Label: isoform X1
- UniProtKB: Q31621 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172749   ⟸   XM_017317260
- Peptide Label: isoform X1
- UniProtKB: Q31621 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030105368   ⟸   XM_030249508
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001347459   ⟸   NM_001360530
- Peptide Label: precursor
RefSeq Acc Id: ENSMUSP00000158155   ⟸   ENSMUST00000237402
RefSeq Acc Id: ENSMUSP00000157660   ⟸   ENSMUST00000236322
RefSeq Acc Id: ENSMUSP00000037088   ⟸   ENSMUST00000042121
Protein Domains
Ig-like   Ig-like C1-type

Promoters
RGD ID:13675664
Promoter ID:EPDNEW_M21981
Type:initiation region
Name:H2-DMa_1
Description:Mus musculus histocompatibility 2, class II, locus DMa (H2-DMa),transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21982  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,122,846 - 34,122,906EPDNEW
RGD ID:13675666
Promoter ID:EPDNEW_M21982
Type:initiation region
Name:H2-DMa_2
Description:Mus musculus histocompatibility 2, class II, locus DMa (H2-DMa),transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21981  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381734,135,632 - 34,135,692EPDNEW
RGD ID:6828206
Promoter ID:MM_KWN:23165
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B6,   Spleen
Transcripts:ENSMUST00000042121,   UC008CBM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361734,271,591 - 34,272,697 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95921 AgrOrtholog
Ensembl Genes ENSMUSG00000037649 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000037088 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000157660 UniProtKB/TrEMBL
  ENSMUSP00000158155 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000042121 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000236322 UniProtKB/TrEMBL
  ENSMUST00000237402 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.320.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_a/b_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_a_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95921 ENTREZGENE
NCBI Gene 14998 ENTREZGENE
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen H2-DMa PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MHC_II_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494BAR2_MOUSE UniProtKB/TrEMBL
  DMA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q31096_MOUSE UniProtKB/TrEMBL
  Q31106_MOUSE UniProtKB/TrEMBL
  Q31107_MOUSE UniProtKB/TrEMBL
  Q31108_MOUSE UniProtKB/TrEMBL
  Q31607_MOUSE UniProtKB/TrEMBL
  Q31621 ENTREZGENE, UniProtKB/TrEMBL
  Q61832_MOUSE UniProtKB/TrEMBL
  Q95605_MOUSE UniProtKB/TrEMBL
  Q95606_MOUSE UniProtKB/TrEMBL
  Q9BCZ3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q9QWV0 UniProtKB/TrEMBL