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Gene: H2-DMa (histocompatibility 2, class II, locus DMa) Mus musculus
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Symbol: H2-DMa
Name: histocompatibility 2, class II, locus DMa
Description: Predicted to have MHC class II protein complex binding activity. Involved in several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; chaperone cofactor-dependent protein refolding; and positive regulation of immune response. Localizes to the endosome membrane; lysosomal membrane; and multivesicular body. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human HLA-DMA (major histocompatibility complex, class II, DM alpha); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: class II histocompatibility antigen, M alpha chain; H-2Ma; H2-M alpha; H2-Ma; histocompatibility 2, class II, locus Ma; MHC class II antigen DMa
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381734,119,693 - 34,139,101 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371734,272,616 - 34,275,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361733,746,082 - 33,749,555 (+)NCBImm8
Celera1736,874,856 - 36,890,963 (+)NCBICelera
Cytogenetic Map17 B1NCBI
cM Map1717.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on H2-DMa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551725
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.