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ONTOLOGY REPORT - ANNOTATIONS


Term:etazolate
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Accession:CHEBI:138502 term browser browse the term
Definition:A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.
Synonyms:exact_synonym: ethyl 1-ethyl-4-(2-isopropylidenehydrazino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
 related_synonym: 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)-5-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl ester;   1H-pyrazolo(3,4-b)pyridine-5-carboxylic acid, 1-ethyl-4-((1-methylethylidene)hydrazino)-, ethyl ester;   EHT-0202;   Formula=C14H19N5O2;   InChI=1S/C14H19N5O2/c1-5-19-13-10(8-16-19)12(18-17-9(3)4)11(7-15-13)14(20)21-6-2/h7-8H,5-6H2,1-4H3,(H,15,18);   InChIKey=OPQRBXUBWHDHPQ-UHFFFAOYSA-N;   SMILES=CCN1C2=NC=C(C(=C2C=N1)NN=C(C)C)C(=O)OCC;   SQ-20,009;   etazolato;   etazolatum;   ethyl 1-ethyl-4-(2-isopropylidenehydrazino)pyrazolo[3,4-b]pyridine-5-carboxylate;   ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[3,4-b]pyridine-5-carboxylate;   ethyl 1-ethyl-4-(2-propan-2-ylidenehydrazinyl)pyrazolo[4,5-e]pyridine-5-carboxylate;   ethyl 1-ethyl-4-[2-(1-methylethylidene)hydrazino]-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
 alt_id: CHEBI:93135
 xref: CAS:51022-77-6;   Chemspider:3162;   LINCS:LSM-3446
 xref_mesh: MESH:D004974
 xref: PMID:18397369;   PMID:20223232;   PMID:22698578;   PMID:23178198;   PMID:23384434;   PMID:23926692;   PMID:23974048;   PMID:24434771;   PMID:24705918;   PMID:25120105;   PMID:25136630;   PMID:27988361;   PMID:449623;   PMID:6131949;   PMID:6132997;   PMID:6991258;   Pubchem:3277;   Reaxys:548872;   Wikipedia:Etazolate


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etazolate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      biological role 19726
        pharmacological role 18808
          neurotransmitter agent 16439
            GABA agent 15435
              etazolate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      chalcogen 19366
                        oxygen atom 19327
                          oxygen molecular entity 19327
                            hydroxides 19071
                              organic hydroxy compound 18641
                                alcohol 14985
                                  primary alcohol 13880
                                    ethanols 8103
                                      ethanol 8103
                                        ethyl ester 3176
                                          etazolate 2
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