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Gene: S100a8 (S100 calcium binding protein A8 (calgranulin A)) Mus musculus
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Symbol: S100a8
Name: S100 calcium binding protein A8 (calgranulin A)
Description: Predicted to have several functions, including arachidonic acid binding activity; metal ion binding activity; and signaling receptor binding activity. Involved in astrocyte development and positive regulation of peptide secretion. Predicted to localize to the cytosol; extracellular space; and intermediate filament cytoskeleton. Human ortholog(s) of this gene implicated in myocarditis. Is expressed in several structures, including bone marrow; extraembryonic component; female reproductive system; and liver. Orthologous to human S100A8 (S100 calcium binding protein A8); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60B8Ag; AI323541; B8Ag; Caga; calgranulin-A; CFAg; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; MRP-8; MRP8; p8; pro-inflammatory S100 cytokine; protein S100-A8; S100 calcium-binding protein A8
Orthologs:
Homo sapiens (human) : S100A8 (S100 calcium binding protein A8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : S100a8 (S100 calcium binding protein A8)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : S100A8 (S100 calcium binding protein A8)
Canis lupus familiaris (dog) : S100A8 (S100 calcium binding protein A8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S100a8 (S100 calcium binding protein A8)
Sus scrofa (pig) : S100A8 (S100 calcium binding protein A8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38390,669,071 - 90,670,034 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37390,472,993 - 90,473,956 (+)NCBIGRCm37mm9NCBIm37
MGSCv36390,755,012 - 90,755,961 (+)NCBImm8
Celera390,710,479 - 90,711,442 (+)NCBICelera
Cytogenetic Map3 F1NCBI
cM Map339.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on S100a8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733916
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.