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Gene: S100a8 (S100 calcium binding protein A8 (calgranulin A)) Mus musculus
Symbol: S100a8
Name: S100 calcium binding protein A8 (calgranulin A)
Description: Predicted to have several functions, including arachidonic acid binding activity; metal ion binding activity; and signaling receptor binding activity. Involved in astrocyte development and positive regulation of peptide secretion. Predicted to localize to the cytosol; extracellular space; and intermediate filament cytoskeleton. Human ortholog(s) of this gene implicated in myocarditis. Is expressed in several structures, including bone marrow; extraembryonic component; female reproductive system; and liver. Orthologous to human S100A8 (S100 calcium binding protein A8); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60B8Ag; AI323541; B8Ag; Caga; calgranulin-A; CFAg; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; MRP-8; MRP8; p8; pro-inflammatory S100 cytokine; protein S100-A8; S100 calcium-binding protein A8
Homo sapiens (human) : S100A8 (S100 calcium binding protein A8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : S100a8 (S100 calcium binding protein A8)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : S100A8 (S100 calcium binding protein A8)
Canis lupus familiaris (dog) : S100A8 (S100 calcium binding protein A8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S100a8 (S100 calcium binding protein A8)
Sus scrofa (pig) : S100A8 (S100 calcium binding protein A8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38390,669,071 - 90,670,034 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37390,472,993 - 90,473,956 (+)NCBIGRCm37mm9NCBIm37
MGSCv36390,755,012 - 90,755,961 (+)NCBImm8
Celera390,710,479 - 90,711,442 (+)NCBICelera
Cytogenetic Map3 F1NCBI
cM Map339.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on S100a8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733916
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.