Atrx (ATRX, chromatin remodeler) - Rat Genome Database

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Gene: Atrx (ATRX, chromatin remodeler) Mus musculus
Analyze
Symbol: Atrx
Name: ATRX, chromatin remodeler
RGD ID: 1553098
MGI Page MGI
Description: Enables chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to hydroxyurea; positive regulation of DNA metabolic process; and subtelomeric heterochromatin formation. Acts upstream of or within several processes, including male gonad development; positive regulation of transcription by RNA polymerase II; and post-embryonic forelimb morphogenesis. Located in PML body and chromosome. Colocalizes with chromosome, telomeric region. Is expressed in several structures, including alimentary system; early embryo; egg cylinder; genitourinary system; and nervous system. Used to study alpha thalassemia-X-linked intellectual disability syndrome. Human ortholog(s) of this gene implicated in X-linked mental retardation-hypotonic facies syndrome-1; alpha thalassemia-X-linked intellectual disability syndrome; alpha-thalassemia myelodysplasia syndrome; high grade glioma; and lung small cell carcinoma. Orthologous to human ATRX (ATRX chromatin remodeler).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4833408C14Rik; AI447451; alpha thalassemia/mental retardation syndrome (X-linked); alpha thalassemia/mental retardation syndrome X-linked; alpha thalassemia/mental retardation syndrome X-linked homolog; ATP-dependent helicase ATRX; ATR2; DXHXS6677; DXHXS6677E; heterochromatin protein 2; HP1 alpha-interacting protein; HP1-BP; HP1-BP38; Hp1b; Hp1bp2; Hp1bp38; MRXS3; Rad; Rad54; RAD54L; RIKEN cDNA 4833408C14 gene; transcriptional regulator ATRX; X; X-linked nuclear protein; XH2; Xnp; ZNF-HX
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm19194  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X104,841,221 - 104,972,978 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX104,841,221 - 104,973,009 (-)EnsemblGRCm39 Ensembl
GRCm38X105,797,615 - 105,929,372 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX105,797,615 - 105,929,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X102,992,954 - 103,124,711 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X102,002,872 - 102,132,061 (-)NCBIMGSCv36mm8
CeleraX92,651,743 - 92,783,324 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenoid cystic carcinoma  (ISO)
adrenocortical carcinoma  (ISO)
alpha thalassemia-X-linked intellectual disability syndrome  (IAGP,ISO)
alpha-thalassemia myelodysplasia syndrome  (ISO)
anaplastic astrocytoma  (ISO)
atypical teratoid rhabdoid tumor  (ISO)
autistic disorder  (ISO)
autosomal hemophilia A  (ISO)
bone osteosarcoma  (ISO)
brachydactyly  (IMP)
Craniofacial Abnormalities  (ISO)
cryptorchidism  (ISO)
Developmental Disabilities  (ISO)
Developmental Disease  (ISO)
disorder of sexual development  (ISO)
Dwarfism  (ISO)
factor VIII deficiency  (ISO)
Gastro-Enteropancreatic Neuroendocrine Tumor  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
Growth Disorders  (ISO)
high grade glioma  (ISO)
Huntington's disease  (IEP)
intellectual disability  (ISO)
islet cell tumor  (ISO)
lung adenocarcinoma  (ISO)
Lung Carcinoid Tumors  (ISO)
lung small cell carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
malignant astrocytoma  (ISO)
melanoma  (ISO)
Menkes disease  (ISO)
microcephaly  (ISO)
Muscle Hypotonia  (ISO)
myelodysplastic syndrome  (ISO)
Nervous System Malformations  (ISO)
neuroblastoma  (ISO)
Neurodevelopmental Disorders  (ISO)
neuroendocrine tumor  (ISO)
oligodendroglioma  (ISO)
osteosarcoma  (ISO)
pancreatic cancer  (ISO)
penile disease  (ISO)
sarcoma  (ISO)
schizophrenia  (ISO)
spermatogenic failure 57  (ISO)
stomach cancer  (IGI)
syndromic X-linked intellectual disability Lubs type  (ISO)
thoracic disease  (ISO)
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia  (ISO)
X-Linked Intellectual Developmental Disorders  (ISO)
X-linked mental retardation-hypotonic facies syndrome-1  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-pilocarpine  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
4-vinylcyclohexene dioxide  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Brevetoxin B  (ISO)
Brodifacoum  (ISO)
butanal  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
chloroprene  (ISO)
clobetasol  (EXP)
clorgyline  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
coumarin  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (EXP)
deoxynivalenol  (EXP)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
diquat  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
ethanol  (EXP,ISO)
flutamide  (ISO)
folic acid  (EXP)
fonofos  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
geldanamycin  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (EXP,ISO)
idarubicin  (EXP)
irinotecan  (ISO)
ivermectin  (ISO)
josamycin  (ISO)
menadione  (EXP)
methoxychlor  (EXP)
methylparaben  (ISO)
miconazole  (EXP)
mitomycin C  (ISO)
morphine  (EXP)
N-ethyl-N-nitrosourea  (ISO)
naphthalene  (ISO)
nicotine  (EXP,ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
potassium chromate  (ISO)
propiconazole  (EXP)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
succimer  (EXP,ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
terbufos  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
theophylline  (ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
tungsten  (EXP)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal behavior  (IAGP)
abnormal developmental patterning  (IEA)
abnormal ectoplacental cone morphology  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal heart morphology  (IEA)
abnormal imprinting  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal retina ganglion layer morphology  (IAGP)
abnormal retina horizontal cell morphology  (IAGP)
abnormal retina inner nuclear layer morphology  (IAGP)
abnormal retina morphology  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal trophectoderm morphology  (IAGP)
absent dentate gyrus  (IAGP)
absent gastric milk in neonates  (IAGP)
decreased amacrine cell number  (IAGP)
decreased birth body size  (IAGP)
decreased body weight  (IAGP)
decreased cell proliferation  (IAGP)
decreased embryo size  (IAGP)
decreased hippocampus pyramidal cell number  (IAGP)
decreased trophoblast giant cell number  (IAGP)
decreased tumor latency  (IAGP)
disorganized extraembryonic tissue  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
impaired contextual conditioning behavior  (IAGP)
increased osteosarcoma incidence  (IAGP)
loss of cortex neurons  (IAGP)
loss of hippocampal neurons  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
reduced long-term potentiation  (IAGP)
small ectoplacental cone  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas. Abedalthagafi M, etal., Mod Pathol. 2013 Nov;26(11):1425-32. doi: 10.1038/modpathol.2013.90. Epub 2013 Jun 14.
2. Alpha-thalassemia intellectual disability: variable phenotypic expression among males with a recurrent nonsense mutation - c.109C>T (p.R37X). Basehore MJ, etal., Clin Genet. 2014 May 7. doi: 10.1111/cge.12420.
3. Novel ATRX gene damaging missense mutation c.6740A>C segregates with profound to severe intellectual deficiency without alpha thalassaemia. Bouazzi H, etal., Indian J Med Res. 2016 Jan;143(1):43-8. doi: 10.4103/0971-5916.178589.
4. Expression and prognostic impact of alpha thalassemia/mental retardation X-linked and death domain-associated protein in human lung cancer. Buentzel J, etal., Medicine (Baltimore). 2019 Aug;98(31):e16712. doi: 10.1097/MD.0000000000016712.
5. ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples samples. Cai J, etal., Oncotarget. 2014 May 15;5(9):2551-61.
6. Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival. Chaurasia A, etal., J Korean Med Sci. 2016 Aug;31(8):1208-14. doi: 10.3346/jkms.2016.31.8.1208. Epub 2016 May 30.
7. Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance. Du M, etal., Lung Cancer. 2018 Jun;120:113-121. doi: 10.1016/j.lungcan.2018.04.008. Epub 2018 Apr 12.
8. A nonsense mutation of the ATRX gene causing mild mental retardation and epilepsy. Guerrini R, etal., Ann Neurol. 2000 Jan;47(1):117-21.
9. Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Kannan K, etal., Oncotarget. 2012 Oct;3(10):1194-203.
10. Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors. Kim HS, etal., Anticancer Res. 2015 Jun;35(6):3501-10.
11. Mutations of codon 2085 in the helicase domain of ATRX are recurrent and cause ATRX syndrome. Lacoste C, etal., Clin Genet. 2013 Dec 1. doi: 10.1111/cge.12319.
12. A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. Le Douarin B, etal., EMBO J 1996 Dec 2;15(23):6701-15.
13. ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease. Lee J, etal., Cell Death Differ. 2012 Jul;19(7):1109-16. doi: 10.1038/cdd.2011.196. Epub 2012 Jan 13.
14. Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas. Liau JY, etal., Mod Pathol. 2015 Dec;28(12):1545-54. doi: 10.1038/modpathol.2015.114. Epub 2015 Oct 2.
15. [Mutation analysis for a Chinese family featuring X-linked alpha thalassemia/mental retardation syndrome]. Lin SB, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2013 Dec;30(6):654-8. doi: 10.3760/cma.j.issn.1003-9406.2013.06.004.
16. Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors. Marinoni I, etal., Gastroenterology. 2014 Feb;146(2):453-60.e5. doi: 10.1053/j.gastro.2013.10.020. Epub 2013 Oct 19.
17. MGDs mouse GO annotations MGD data from the GO Consortium
18. MGD IEA MGD IEA
19. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
20. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
21. Decreased expression of the chromatin remodeler ATRX associates with melanoma progression. Qadeer ZA, etal., J Invest Dermatol. 2014 Jun;134(6):1768-72. doi: 10.1038/jid.2014.45. Epub 2014 Jan 27.
22. Mouse MP Annotation Import Pipeline RGD automated import pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly. Solomon LA, etal., Hum Mol Genet. 2013 Dec 15;22(24):5015-25. doi: 10.1093/hmg/ddt351. Epub 2013 Jul 25.
26. Large-scale identification of mammalian proteins localized to nuclear sub-compartments. Sutherland HG, etal., Hum Mol Genet 2001 Sep 1;10(18):1995-2011.
27. Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. Takeda H, etal., Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2057-65. doi: 10.1073/pnas.1603223113. Epub 2016 Mar 22.
28. Loss of ATRX expression predicts worse prognosis in pulmonary carcinoid tumors. Terra Md SBSP, etal., Hum Pathol. 2019 Dec;94:78-85. doi: 10.1016/j.humpath.2019.08.022. Epub 2019 Sep 6.
29. XNP mutation in a large family with Juberg-Marsidi syndrome. Villard L, etal., Nat Genet. 1996 Apr;12(4):359-60.
30. Expanding phenotype of XNP mutations: mild to moderate mental retardation. Yntema HG, etal., Am J Med Genet. 2002 Jul 1;110(3):243-7.
Additional References at PubMed
PMID:7874112   PMID:8162050   PMID:8889548   PMID:8921375   PMID:9545503   PMID:9607915   PMID:9736627   PMID:10349636   PMID:10570185   PMID:10757799   PMID:10922068   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11544199   PMID:11823444   PMID:12520002   PMID:12904583   PMID:14519686   PMID:14610273   PMID:14654002   PMID:14681479   PMID:15242786   PMID:15252119  
PMID:15522233   PMID:15668733   PMID:16141072   PMID:16141073   PMID:16452087   PMID:16602821   PMID:16628246   PMID:16935872   PMID:17296936   PMID:17503331   PMID:18227278   PMID:18287559  
PMID:18366812   PMID:18799693   PMID:18842153   PMID:19005673   PMID:19020049   PMID:19088125   PMID:19538749   PMID:19571810   PMID:19615340   PMID:19774083   PMID:20110566   PMID:20150414  
PMID:20159591   PMID:20211137   PMID:20548051   PMID:20651253   PMID:20865721   PMID:20885787   PMID:21029860   PMID:21057507   PMID:21209221   PMID:21267068   PMID:21317870   PMID:21357745  
PMID:21421568   PMID:21427128   PMID:21672208   PMID:21677750   PMID:21873635   PMID:22500635   PMID:22573614   PMID:22918800   PMID:23114596   PMID:23284920   PMID:23362347   PMID:23444137  
PMID:23563309   PMID:23754746   PMID:24270455   PMID:24386478   PMID:24651726   PMID:24946904   PMID:24990380   PMID:25395668   PMID:25417162   PMID:25452430   PMID:25865896   PMID:26012739  
PMID:26159997   PMID:26206133   PMID:26340527   PMID:26477563   PMID:26496610   PMID:26836306   PMID:26936505   PMID:27171262   PMID:27863708   PMID:28093507   PMID:28173139   PMID:28186538  
PMID:28341773   PMID:28358373   PMID:28666128   PMID:28684628   PMID:29095838   PMID:29535300   PMID:29719265   PMID:29785027   PMID:29883366   PMID:30126901   PMID:30186101   PMID:30204892  
PMID:30231518   PMID:30335163   PMID:30510993   PMID:31029404   PMID:31040226   PMID:31671722   PMID:31713968   PMID:31895940   PMID:32376827   PMID:32610139   PMID:32821827   PMID:33197500  
PMID:34162889   PMID:34321999   PMID:34474245   PMID:34722536   PMID:34763709   PMID:35976056   PMID:35998910   PMID:36010860   PMID:36073547   PMID:36440760   PMID:36635505   PMID:37072228  
PMID:37171606   PMID:37196079   PMID:37200088   PMID:37253089   PMID:37296979   PMID:37925436   PMID:38609433   PMID:38616920  


Genomics

Comparative Map Data
Atrx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X104,841,221 - 104,972,978 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX104,841,221 - 104,973,009 (-)EnsemblGRCm39 Ensembl
GRCm38X105,797,615 - 105,929,372 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX105,797,615 - 105,929,403 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X102,992,954 - 103,124,711 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X102,002,872 - 102,132,061 (-)NCBIMGSCv36mm8
CeleraX92,651,743 - 92,783,324 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX47.26NCBI
ATRX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X77,504,880 - 77,786,216 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX77,504,880 - 77,786,233 (-)EnsemblGRCh38hg38GRCh38
GRCh37X76,760,358 - 77,041,702 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X76,647,012 - 76,928,375 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX77,001,253 - 77,282,613 (-)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX70,349,443 - 70,629,029 (-)NCBIHuRef
CHM1_1X76,653,073 - 76,934,420 (-)NCBICHM1_1
T2T-CHM13v2.0X75,942,420 - 76,223,770 (-)NCBIT2T-CHM13v2.0
Atrx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X74,916,548 - 75,062,880 (-)NCBIGRCr8
mRatBN7.2X70,850,981 - 70,997,330 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX70,850,981 - 70,997,330 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX72,359,919 - 72,506,253 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X75,860,229 - 76,006,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X73,423,392 - 73,569,729 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X76,820,110 - 76,979,155 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX76,820,329 - 76,979,115 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX76,692,970 - 76,708,878 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X77,469,497 - 77,515,204 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X55,943,493 - 56,101,756 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X93,903,794 - 94,051,337 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X94,034,366 - 94,057,029 (-)NCBI
CeleraX72,164,814 - 72,309,854 (-)NCBICelera
Cytogenetic MapXq22NCBI
Atrx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955557947,167 - 1,252,724 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955557947,368 - 1,252,701 (-)NCBIChiLan1.0ChiLan1.0
ATRX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X77,081,989 - 77,368,610 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X77,085,587 - 77,372,212 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X66,682,968 - 66,969,421 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X76,795,574 - 77,083,486 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX76,795,574 - 77,083,486 (-)Ensemblpanpan1.1panPan2
ATRX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X59,772,067 - 60,107,016 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX59,774,585 - 60,106,980 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX50,787,446 - 51,120,278 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X61,011,471 - 61,270,437 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX61,011,677 - 61,270,443 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X58,719,357 - 59,051,934 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X60,325,606 - 60,661,270 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X59,917,163 - 60,249,816 (-)NCBIUU_Cfam_GSD_1.0
Atrx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X42,229,198 - 42,451,804 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366832,495,959 - 2,718,620 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366832,496,307 - 2,718,539 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATRX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX61,584,848 - 61,872,287 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X61,584,028 - 61,872,341 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X70,390,618 - 70,509,341 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATRX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X66,449,830 - 66,737,220 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX66,448,449 - 66,737,164 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606714,772,636 - 15,066,083 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Atrx
2075 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2965
Count of miRNA genes:945
Interacting mature miRNAs:1320
Transcripts:ENSMUST00000101305, ENSMUST00000113573, ENSMUST00000123174, ENSMUST00000126345, ENSMUST00000127221, ENSMUST00000128968, ENSMUST00000130980, ENSMUST00000133543, ENSMUST00000134381, ENSMUST00000134507, ENSMUST00000137453, ENSMUST00000138765, ENSMUST00000141609, ENSMUST00000142235, ENSMUST00000143361, ENSMUST00000146193, ENSMUST00000150914, ENSMUST00000154866, ENSMUST00000155445
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined47179121129764756Mouse
13208552Wght12_mweight 12 (mouse)X94043606149782996Mouse
4141803Lmr30_mleishmaniasis resistance 30 (mouse)Not determined85062606119062720Mouse
13208556Lgth14_mbody length 14 (mouse)X94043606149782996Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X80189914114190059Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X54045360148782996Mouse
1357500Mdmsc6_mmodifier of muscularity 6 (mouse)Not determinedX75306671109306758Mouse
1357823Spha3_msperm head anomaly 3 (mouse)Not determinedX102055848162758941Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined71453852139203212Mouse

Markers in Region
DXMit213  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X105,864,610 - 105,864,721UniSTSGRCm38
MGSCv37X103,059,949 - 103,060,060UniSTSGRCm37
CeleraX92,718,708 - 92,718,837UniSTS
Cytogenetic MapXDUniSTS
cM MapX44.4UniSTS
Whitehead GeneticX31.7UniSTS
Whitehead/MRC_RHX1159.63UniSTS
Whitehead_YACX UniSTS
AI447451  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X105,797,898 - 105,797,998UniSTSGRCm38
MGSCv37X102,993,237 - 102,993,337UniSTSGRCm37
CeleraX92,652,026 - 92,652,126UniSTS
Cytogenetic MapXDUniSTS
cM MapX43.8UniSTS
Whitehead/MRC_RHX1159.73UniSTS
RH126483  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X105,873,855 - 105,874,067UniSTSGRCm38
MGSCv37X103,069,194 - 103,069,406UniSTSGRCm37
CeleraX92,728,028 - 92,728,240UniSTS
Cytogenetic MapXDUniSTS
cM MapX42.0UniSTS
Whitehead/MRC_RHX1159.73UniSTS
MARC_6759-6760:992007400:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X105,855,973 - 105,856,579UniSTSGRCm38
MGSCv37X103,051,312 - 103,051,918UniSTSGRCm37
CeleraX92,710,046 - 92,710,652UniSTS
Cytogenetic MapXDUniSTS
cM MapX43.8UniSTS
GDB:596212  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X105,830,948 - 105,832,496UniSTSGRCm38
MGSCv37X103,026,287 - 103,027,835UniSTSGRCm37
CeleraX92,685,056 - 92,686,604UniSTS
Cytogenetic MapXDUniSTS
cM MapX43.8UniSTS
GDB:596250  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X105,801,406 - 105,802,803UniSTSGRCm38
MGSCv37X102,996,745 - 102,998,142UniSTSGRCm37
CeleraX92,655,534 - 92,656,931UniSTS
Cytogenetic MapXDUniSTS
cM MapX43.8UniSTS
Atrx  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXDUniSTS
cM MapX47.26UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF026032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL670660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF410140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L34362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000101305   ⟹   ENSMUSP00000098863
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,925,561 - 104,972,183 (-)Ensembl
GRCm38.p6 EnsemblX105,881,955 - 105,928,577 (-)Ensembl
Ensembl Acc Id: ENSMUST00000113573   ⟹   ENSMUSP00000109203
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,841,221 - 104,973,009 (-)Ensembl
GRCm38.p6 EnsemblX105,797,615 - 105,929,403 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123174
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,895,043 - 104,918,870 (-)Ensembl
GRCm38.p6 EnsemblX105,851,437 - 105,875,264 (-)Ensembl
Ensembl Acc Id: ENSMUST00000126345
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,943,512 - 104,972,952 (-)Ensembl
GRCm38.p6 EnsemblX105,899,906 - 105,929,346 (-)Ensembl
Ensembl Acc Id: ENSMUST00000127221   ⟹   ENSMUSP00000143664
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,861,676 - 104,869,731 (-)Ensembl
GRCm38.p6 EnsemblX105,818,070 - 105,826,125 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128968   ⟹   ENSMUSP00000121416
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,918,736 - 104,972,972 (-)Ensembl
GRCm38.p6 EnsemblX105,875,130 - 105,929,366 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130980   ⟹   ENSMUSP00000117528
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,931,387 - 104,973,003 (-)Ensembl
GRCm38.p6 EnsemblX105,887,781 - 105,929,397 (-)Ensembl
Ensembl Acc Id: ENSMUST00000133543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,921,975 - 104,923,993 (-)Ensembl
GRCm38.p6 EnsemblX105,878,369 - 105,880,387 (-)Ensembl
Ensembl Acc Id: ENSMUST00000134381   ⟹   ENSMUSP00000122875
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,920,846 - 104,972,973 (-)Ensembl
GRCm38.p6 EnsemblX105,877,240 - 105,929,367 (-)Ensembl
Ensembl Acc Id: ENSMUST00000134507   ⟹   ENSMUSP00000123085
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,920,566 - 104,972,956 (-)Ensembl
GRCm38.p6 EnsemblX105,876,960 - 105,929,350 (-)Ensembl
Ensembl Acc Id: ENSMUST00000137453   ⟹   ENSMUSP00000120246
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,927,962 - 104,972,909 (-)Ensembl
GRCm38.p6 EnsemblX105,884,356 - 105,929,303 (-)Ensembl
Ensembl Acc Id: ENSMUST00000138765
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,845,356 - 104,847,404 (-)Ensembl
GRCm38.p6 EnsemblX105,801,750 - 105,803,798 (-)Ensembl
Ensembl Acc Id: ENSMUST00000141609
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,861,702 - 104,873,252 (-)Ensembl
GRCm38.p6 EnsemblX105,818,096 - 105,829,646 (-)Ensembl
Ensembl Acc Id: ENSMUST00000142235
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,881,985 - 104,890,563 (-)Ensembl
GRCm38.p6 EnsemblX105,838,379 - 105,846,957 (-)Ensembl
Ensembl Acc Id: ENSMUST00000143361
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,844,023 - 104,845,656 (-)Ensembl
GRCm38.p6 EnsemblX105,800,417 - 105,802,050 (-)Ensembl
Ensembl Acc Id: ENSMUST00000146193
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,890,343 - 104,895,132 (-)Ensembl
GRCm38.p6 EnsemblX105,846,737 - 105,851,526 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150914   ⟹   ENSMUSP00000122034
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,920,566 - 104,972,976 (-)Ensembl
GRCm38.p6 EnsemblX105,876,960 - 105,929,370 (-)Ensembl
Ensembl Acc Id: ENSMUST00000154866   ⟹   ENSMUSP00000121291
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,921,047 - 104,972,965 (-)Ensembl
GRCm38.p6 EnsemblX105,877,441 - 105,929,359 (-)Ensembl
Ensembl Acc Id: ENSMUST00000155445
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,881,630 - 104,890,379 (-)Ensembl
GRCm38.p6 EnsemblX105,838,024 - 105,846,773 (-)Ensembl
Ensembl Acc Id: ENSMUST00000196998
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,889,990 - 104,895,420 (-)Ensembl
GRCm38.p6 EnsemblX105,846,384 - 105,851,814 (-)Ensembl
Ensembl Acc Id: ENSMUST00000197302   ⟹   ENSMUSP00000143163
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,900,209 - 104,931,429 (-)Ensembl
GRCm38.p6 EnsemblX105,856,603 - 105,887,823 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198209   ⟹   ENSMUSP00000142726
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,895,609 - 104,919,201 (-)Ensembl
GRCm38.p6 EnsemblX105,852,003 - 105,875,595 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198441   ⟹   ENSMUSP00000143565
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,921,995 - 104,972,844 (-)Ensembl
GRCm38.p6 EnsemblX105,878,389 - 105,929,238 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198448   ⟹   ENSMUSP00000143090
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,920,114 - 104,972,948 (-)Ensembl
GRCm38.p6 EnsemblX105,876,508 - 105,929,342 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198567   ⟹   ENSMUSP00000143007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,869,750 - 104,881,877 (-)Ensembl
GRCm38.p6 EnsemblX105,826,144 - 105,838,271 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199233   ⟹   ENSMUSP00000143015
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,921,086 - 104,972,953 (-)Ensembl
GRCm38.p6 EnsemblX105,877,480 - 105,929,347 (-)Ensembl
Ensembl Acc Id: ENSMUST00000200471   ⟹   ENSMUSP00000143280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX104,909,152 - 104,918,911 (-)Ensembl
GRCm38.p6 EnsemblX105,865,546 - 105,875,305 (-)Ensembl
RefSeq Acc Id: NM_009530   ⟹   NP_033556
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X104,841,221 - 104,972,978 (-)NCBI
GRCm38X105,797,615 - 105,929,372 (-)NCBI
MGSCv37X102,992,954 - 103,124,711 (-)RGD
CeleraX92,651,743 - 92,783,324 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033556   ⟸   NM_009530
- UniProtKB: A2ADH4 (UniProtKB/Swiss-Prot),   Q61687 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000143007   ⟸   ENSMUST00000198567
Ensembl Acc Id: ENSMUSP00000122034   ⟸   ENSMUST00000150914
Ensembl Acc Id: ENSMUSP00000142726   ⟸   ENSMUST00000198209
Ensembl Acc Id: ENSMUSP00000143565   ⟸   ENSMUST00000198441
Ensembl Acc Id: ENSMUSP00000143090   ⟸   ENSMUST00000198448
Ensembl Acc Id: ENSMUSP00000117528   ⟸   ENSMUST00000130980
Ensembl Acc Id: ENSMUSP00000143163   ⟸   ENSMUST00000197302
Ensembl Acc Id: ENSMUSP00000109203   ⟸   ENSMUST00000113573
Ensembl Acc Id: ENSMUSP00000143664   ⟸   ENSMUST00000127221
Ensembl Acc Id: ENSMUSP00000143015   ⟸   ENSMUST00000199233
Ensembl Acc Id: ENSMUSP00000098863   ⟸   ENSMUST00000101305
Ensembl Acc Id: ENSMUSP00000121291   ⟸   ENSMUST00000154866
Ensembl Acc Id: ENSMUSP00000123085   ⟸   ENSMUST00000134507
Ensembl Acc Id: ENSMUSP00000122875   ⟸   ENSMUST00000134381
Ensembl Acc Id: ENSMUSP00000121416   ⟸   ENSMUST00000128968
Ensembl Acc Id: ENSMUSP00000120246   ⟸   ENSMUST00000137453
Ensembl Acc Id: ENSMUSP00000143280   ⟸   ENSMUST00000200471
Protein Domains
ADD   ATRX ADD   Helicase ATP-binding   Helicase C-terminal   PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61687-F1-model_v2 AlphaFold Q61687 1-2476 view protein structure

Promoters
RGD ID:6845509
Promoter ID:MM_KWN:61495
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:OTTMUST00000044144
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X102,996,796 - 102,998,332 (-)MPROMDB
RGD ID:6845510
Promoter ID:MM_KWN:61496
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000044143
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X102,998,631 - 102,999,131 (-)MPROMDB
RGD ID:6845505
Promoter ID:MM_KWN:61498
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000044142
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X103,021,811 - 103,022,311 (-)MPROMDB
RGD ID:6845506
Promoter ID:MM_KWN:61499
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000044141
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X103,024,801 - 103,025,301 (-)MPROMDB
RGD ID:6845507
Promoter ID:MM_KWN:61503
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000044138,   UC009UBC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X103,046,306 - 103,046,806 (-)MPROMDB
RGD ID:6845504
Promoter ID:MM_KWN:61505
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver,   Lung
Transcripts:OTTMUST00000044137
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X103,070,696 - 103,071,597 (-)MPROMDB
RGD ID:6845511
Promoter ID:MM_KWN:61506
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Liver,   MEF_B6
Transcripts:OTTMUST00000058534
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X103,075,246 - 103,076,427 (-)MPROMDB
RGD ID:6845503
Promoter ID:MM_KWN:61510
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000087810,   ENSMUST00000101305,   ENSMUST00000113573,   ENSMUST00000113574,   OTTMUST00000044145,   OTTMUST00000058530,   OTTMUST00000058531,   OTTMUST00000058532,   OTTMUST00000058533,   UC009UBE.1,   UC009UBF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X103,124,136 - 103,124,932 (-)MPROMDB
RGD ID:13681172
Promoter ID:EPDNEW_M24736
Type:multiple initiation site
Name:Atrx_2
Description:Mus musculus ATRX, chromatin remodeler , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M24737  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X105,928,577 - 105,928,637EPDNEW
RGD ID:13681176
Promoter ID:EPDNEW_M24737
Type:initiation region
Name:Atrx_1
Description:Mus musculus ATRX, chromatin remodeler , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M24736  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X105,929,350 - 105,929,410EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103067 AgrOrtholog
Ensembl Genes ENSMUSG00000031229 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000101305.9 UniProtKB/TrEMBL
  ENSMUST00000113573 ENTREZGENE
  ENSMUST00000113573.8 UniProtKB/Swiss-Prot
  ENSMUST00000127221.8 UniProtKB/TrEMBL
  ENSMUST00000128968.8 UniProtKB/TrEMBL
  ENSMUST00000130980.2 UniProtKB/TrEMBL
  ENSMUST00000134381.8 UniProtKB/TrEMBL
  ENSMUST00000134507.8 UniProtKB/TrEMBL
  ENSMUST00000137453.8 UniProtKB/TrEMBL
  ENSMUST00000150914.8 UniProtKB/TrEMBL
  ENSMUST00000154866.8 UniProtKB/TrEMBL
  ENSMUST00000197302.5 UniProtKB/TrEMBL
  ENSMUST00000198209.2 UniProtKB/TrEMBL
  ENSMUST00000198441.5 UniProtKB/TrEMBL
  ENSMUST00000198448.5 UniProtKB/TrEMBL
  ENSMUST00000198567.2 UniProtKB/TrEMBL
  ENSMUST00000199233.5 UniProtKB/TrEMBL
  ENSMUST00000200471.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.10810 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SWI2/SNF2 ATPases, N-terminal domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADD_ATRX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARIP4-like UniProtKB/TrEMBL
  ATRX_domain-containing UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNF2-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNF2/RAD54-like_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNF2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22589 UniProtKB/Swiss-Prot
MGD MGI:103067 ENTREZGENE
NCBI Gene 22589 ENTREZGENE
PANTHER PTHR45797 UniProtKB/TrEMBL
  RAD54-LIKE UniProtKB/TrEMBL
  TRANSCRIPTIONAL REGULATOR ATRX UniProtKB/Swiss-Prot
  TRANSCRIPTIONAL REGULATOR ATRX UniProtKB/Swiss-Prot
  TRANSCRIPTIONAL REGULATOR ATRX UniProtKB/TrEMBL
  TRANSCRIPTIONAL REGULATOR ATRX UniProtKB/TrEMBL
Pfam ADD_ATRX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Helicase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNF2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atrx PhenoGen
PROSITE ADD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DEXDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HELICc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JED2_MOUSE UniProtKB/TrEMBL
  A0A0G2JF35_MOUSE UniProtKB/TrEMBL
  A0A0G2JF42_MOUSE UniProtKB/TrEMBL
  A0A0G2JFA5_MOUSE UniProtKB/TrEMBL
  A0A0G2JFG6_MOUSE UniProtKB/TrEMBL
  A0A0G2JFR8_MOUSE UniProtKB/TrEMBL
  A0A0G2JGH3_MOUSE UniProtKB/TrEMBL
  A0A0G2JGR1_MOUSE UniProtKB/TrEMBL
  A2ADH4 ENTREZGENE
  A6PWK7_MOUSE UniProtKB/TrEMBL
  A6PWK8_MOUSE UniProtKB/TrEMBL
  A6PWK9_MOUSE UniProtKB/TrEMBL
  A6PWL2_MOUSE UniProtKB/TrEMBL
  ATRX_MOUSE UniProtKB/Swiss-Prot
  F6RDB7_MOUSE UniProtKB/TrEMBL
  Q3TA30_MOUSE UniProtKB/TrEMBL
  Q3TP53_MOUSE UniProtKB/TrEMBL
  Q3TSV4_MOUSE UniProtKB/TrEMBL
  Q3UU22_MOUSE UniProtKB/TrEMBL
  Q3UY26_MOUSE UniProtKB/TrEMBL
  Q3UZ76_MOUSE UniProtKB/TrEMBL
  Q61687 ENTREZGENE
  Q8BSH0_MOUSE UniProtKB/TrEMBL
  Q8C2S3_MOUSE UniProtKB/TrEMBL
  Q8C4Z6_MOUSE UniProtKB/TrEMBL
UniProt Secondary A2ADH4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-21 Atrx  ATRX, chromatin remodeler    alpha thalassemia/mental retardation syndrome X-linked  Symbol and/or name change 5135510 APPROVED
2016-04-05 Atrx  alpha thalassemia/mental retardation syndrome X-linked  4833408C14Rik  RIKEN cDNA 4833408C14 gene  Data merged from RGD:1608143 737654 PROVISIONAL
2015-12-22 Atrx  alpha thalassemia/mental retardation syndrome X-linked    alpha thalassemia/mental retardation syndrome X-linked homolog (human)  Symbol and/or name change 5135510 APPROVED