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Gene: Pias1 (protein inhibitor of activated STAT 1) Mus musculus
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Symbol: Pias1
Name: protein inhibitor of activated STAT 1
Description: Exhibits transcription factor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including fat cell differentiation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein sumoylation. Localizes to the nucleus. Colocalizes with the PML body. Is expressed in several structures, including branchial arch; genitourinary system; sensory organ; tooth; and trunk mesenchyme. Orthologous to human PIAS1 (protein inhibitor of activated STAT 1); PARTICIPATES IN aldosterone signaling pathway; ataxia telangiectasia-mutated (ATM) signaling pathway; Hedgehog signaling pathway; INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 2900068C24Rik; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; GBP; protein inhibitor of activated STAT protein 1; RING-type E3 ubiquitin transferase PIAS1
Orthologs:
Homo sapiens (human) : PIAS1 (protein inhibitor of activated STAT 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pias1 (protein inhibitor of activated STAT, 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias1 (protein inhibitor of activated STAT 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS1 (protein inhibitor of activated STAT 1)
Canis lupus familiaris (dog) : PIAS1 (protein inhibitor of activated STAT 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias1 (protein inhibitor of activated STAT 1)
Sus scrofa (pig) : PIAS1 (protein inhibitor of activated STAT 1)
Chlorocebus sabaeus (green monkey) : PIAS1 (protein inhibitor of activated STAT 1)
Heterocephalus glaber (naked mole-rat) : Pias1 (protein inhibitor of activated STAT 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl962,878,368 - 62,987,924 (-)Ensembl
GRCm38962,878,366 - 62,980,879 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37962,727,884 - 62,828,686 (-)NCBIGRCm37mm9NCBIm37
MGSCv36962,678,083 - 62,778,885 (-)NCBImm8
Celera960,099,154 - 60,199,601 (-)NCBICelera
Cytogenetic Map9 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pias1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317274
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.