Pias1 (protein inhibitor of activated STAT 1) - Rat Genome Database

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Gene: Pias1 (protein inhibitor of activated STAT 1) Mus musculus
Analyze
Symbol: Pias1
Name: protein inhibitor of activated STAT 1
RGD ID: 1317274
MGI Page MGI
Description: Enables several functions, including SUMO ligase activity; transcription cis-regulatory region binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein sumoylation. Located in nuclear periphery. Is active in several cellular components, including glutamatergic synapse; postsynaptic cytosol; and presynaptic cytosol. Colocalizes with PML body. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; sensory organ; and trunk mesenchyme. Orthologous to human PIAS1 (protein inhibitor of activated STAT 1).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2900068C24Rik; Ddxbp; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; GB; GBP; protein inhibitor of activated STAT protein 1; RING-type E3 ubiquitin transferase PIAS1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39962,785,648 - 62,888,161 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl962,785,650 - 62,895,206 (-)EnsemblGRCm39 Ensembl
GRCm38962,878,366 - 62,980,879 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl962,878,368 - 62,987,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv37962,727,884 - 62,828,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36962,678,083 - 62,778,885 (-)NCBIMGSCv36mm8
Celera960,099,154 - 60,199,601 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map933.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
amitrole  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chlorpromazine  (EXP)
choline  (EXP)
clofibric acid  (ISO)
clotrimazole  (ISO)
colforsin daropate hydrochloride  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloromethane  (EXP)
dorsomorphin  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (EXP)
L-methionine  (EXP)
lipopolysaccharide  (EXP)
manganese(II) chloride  (EXP,ISO)
methidathion  (EXP)
methylmercury chloride  (ISO)
motexafin gadolinium  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
oxaliplatin  (ISO)
oxybenzone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (EXP)
potassium chromate  (ISO)
propiconazole  (ISO)
rifampicin  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
theophylline  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
urethane  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
zinc acetate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental glomerulosclerosis. Liang Y, etal., Pediatr Nephrol. 2009 Sep;24(9):1661-71. doi: 10.1007/s00467-009-1163-4. Epub 2009 Apr 7.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10. Mouse MP Annotation Import Pipeline RGD automated import pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Melatonin attenuates brain contusion-induced oxidative insult, inactivation of signal transducers and activators of transcription 1, and upregulation of suppressor of cytokine signaling-3 in rats. Tsai MC, etal., J Pineal Res. 2011 Sep;51(2):233-45. doi: 10.1111/j.1600-079X.2011.00885.x. Epub 2011 May 4.
13. JAK/STAT signal transduction: regulators and implication in hematological malignancies. Valentino L and Pierre J, Biochem Pharmacol. 2006 Mar 14;71(6):713-21. Epub 2006 Jan 19.
14. Interactions of the mineralocorticoid receptor--within and without. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
Additional References at PubMed
PMID:9724754   PMID:10349636   PMID:10854042   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11117529   PMID:11788578   PMID:11877418   PMID:12077349   PMID:12223491   PMID:12477932  
PMID:12520002   PMID:12855578   PMID:14500712   PMID:14610273   PMID:14611647   PMID:15123625   PMID:15208321   PMID:15226823   PMID:15229330   PMID:15280358   PMID:15311277   PMID:15337742  
PMID:15489334   PMID:15507114   PMID:15657437   PMID:15782199   PMID:16127449   PMID:16141072   PMID:16141073   PMID:16421255   PMID:16522640   PMID:16600910   PMID:16816390   PMID:17159996  
PMID:17178721   PMID:17187077   PMID:17440973   PMID:17509614   PMID:17540171   PMID:17606919   PMID:17938210   PMID:17967808   PMID:18056374   PMID:18083234   PMID:18287559   PMID:18799693  
PMID:18832723   PMID:18927467   PMID:19620279   PMID:20059953   PMID:20209145   PMID:20412781   PMID:20711444   PMID:20966256   PMID:21288202   PMID:21677750   PMID:21717107   PMID:21873635  
PMID:21931855   PMID:22406621   PMID:22539995   PMID:22549777   PMID:22555612   PMID:22969086   PMID:22988430   PMID:23118920   PMID:23202365   PMID:23515314   PMID:23938469   PMID:24061474  
PMID:24357619   PMID:24582888   PMID:24777831   PMID:24911587   PMID:26157031   PMID:26275350   PMID:26324179   PMID:27009683   PMID:27146268   PMID:27155222   PMID:27239040   PMID:29138280  
PMID:29212953   PMID:30351951   PMID:30419807   PMID:32688147   PMID:32770107   PMID:34187905   PMID:34267330   PMID:34459572   PMID:35377920   PMID:38102979  


Genomics

Comparative Map Data
Pias1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39962,785,648 - 62,888,161 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl962,785,650 - 62,895,206 (-)EnsemblGRCm39 Ensembl
GRCm38962,878,366 - 62,980,879 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl962,878,368 - 62,987,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv37962,727,884 - 62,828,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36962,678,083 - 62,778,885 (-)NCBIMGSCv36mm8
Celera960,099,154 - 60,199,601 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map933.91NCBI
PIAS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381568,054,315 - 68,193,847 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1568,054,309 - 68,198,603 (+)EnsemblGRCh38hg38GRCh38
GRCh371568,346,653 - 68,486,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361566,133,626 - 66,267,467 (+)NCBINCBI36Build 36hg18NCBI36
Build 341566,133,625 - 66,267,456NCBI
Celera1545,234,605 - 45,365,328 (+)NCBICelera
Cytogenetic Map15q23NCBI
HuRef1545,180,222 - 45,311,150 (+)NCBIHuRef
CHM1_11568,465,362 - 68,598,367 (+)NCBICHM1_1
T2T-CHM13v2.01565,875,930 - 66,012,597 (+)NCBIT2T-CHM13v2.0
Pias1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8872,233,566 - 72,347,085 (-)NCBIGRCr8
mRatBN7.2863,338,150 - 63,451,670 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl863,338,150 - 63,438,905 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx868,853,069 - 68,953,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0867,125,523 - 67,226,318 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0864,995,537 - 65,096,314 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0867,771,720 - 67,869,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl867,771,720 - 67,869,019 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0867,500,467 - 67,597,762 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4867,025,248 - 67,123,016 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1867,044,301 - 67,142,058 (-)NCBI
Celera862,756,508 - 62,854,013 (-)NCBICelera
Cytogenetic Map8q24NCBI
Pias1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554507,896,741 - 7,991,027 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554507,896,741 - 7,991,045 (-)NCBIChiLan1.0ChiLan1.0
PIAS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21657,310,791 - 57,445,115 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11561,484,619 - 61,618,957 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01547,006,718 - 47,141,035 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11565,276,530 - 65,410,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1565,276,530 - 65,410,105 (+)Ensemblpanpan1.1panPan2
PIAS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13032,116,363 - 32,232,530 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3032,119,311 - 32,228,945 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3032,050,874 - 32,167,015 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03032,312,019 - 32,428,219 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3032,314,211 - 32,424,739 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13032,240,403 - 32,356,487 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03032,302,308 - 32,418,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03032,548,145 - 32,664,285 (+)NCBIUU_Cfam_GSD_1.0
Pias1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640110,076,935 - 110,207,569 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647127,925,153 - 28,055,632 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647127,925,153 - 28,055,632 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIAS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1165,957,132 - 166,087,239 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11165,957,114 - 166,087,242 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21183,734,088 - 183,951,464 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIAS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12615,294,296 - 15,432,731 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2615,297,934 - 15,432,659 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048126,035,605 - 126,174,441 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pias1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247814,893,308 - 5,046,582 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247814,893,308 - 5,046,928 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pias1
2744 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:574
Count of miRNA genes:388
Interacting mature miRNAs:437
Transcripts:ENSMUST00000098651
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301782Chol11_mcholesterol 11 (mouse)Not determined92929292963293072Mouse
12790986Pcho9_mplasma cholesterol 9 (mouse)93809957572099575Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
14746993Manh66_mmandible shape 66 (mouse)94981404883814048Mouse
12790992Arlsq1_maortic root lesion size QTL 1 (mouse)93809957572099575Mouse
1301252Etohc3_methanol consumption 3 (mouse)Not determined93503447869034599Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1357709Si5lq3_mserum IGFBP-5 level QTL 3 (mouse)Not determined93311102567111140Mouse
12791002Arlsq2_maortic root lesion size QTL 2 (mouse)93809957572099575Mouse
1301558Stheal8_msoft tissue heal 8 (mouse)Not determined94348071477480860Mouse
1357746Vtbt7_mvertebral trabecular bone trait 7 (mouse)Not determined93073991564740021Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95902438793024534Mouse
1301435Trigq1_mtriglyceride QTL 1 (mouse)Not determined94442817478428262Mouse
1301051Eae9_msusceptibility to experimental allergic encephalomyelitis 9 (mouse)Not determined94942029863239852Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95936994693370128Mouse
1301049El4_mepilepsy 4 (mouse)Not determined94942029867151448Mouse
1301692Hts_mhypothermia sensitivity (mouse)Not determined93251117266511421Mouse
1558968Tbdr1_mbody temperature response to dietary restriction, QTL 1 (mouse)Not determined93503447869034599Mouse
4141071Ath29_matherosclerosis 29 (mouse)Not determined94041959474607925Mouse
4141323Ptnu3_mproteinuria 3 (mouse)Not determined93288970266889836Mouse
1301287Feml2_mfemur length in high growth mice 2 (mouse)Not determined95750728363207282Mouse
1302180Actd4_mactivity-distance traveled 4 (mouse)Not determined93243456366434857Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95902438793024534Mouse
13208563Bmiq8_mbody mass index QTL 8 (mouse)92491129668907282Mouse
4141572Ntta3_mneurotensin transcript abundance 3 (mouse)Not determined4659767165831177Mouse
1301549Bbaa9_mB.burgdorferi-associated arthritis 9 (mouse)Not determined95780504771481754Mouse
1300563Pgia5_mproteoglycan induced arthritis 5 (mouse)Not determined94883105682831177Mouse
13525007Lfhrvq1_mlow frequency time index heart rate varaiblity, QTL 1 (mouse)95878431868556008Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95936994693370128Mouse
1301972Cocrb8_mcocaine related behavior 8 (mouse)Not determined93503447869034599Mouse
1558872Ibdq1_minflammatory bowel disease QTL 1 (mouse)Not determined93397884073439255Mouse
12738449Spcq2_msperm count QTL 2 (mouse)93939988573399885Mouse
1301184Bdln4_mbody length 4 (mouse)Not determined95015132084151448Mouse
4141676Neogq1_mneonatal growth QTL 1 (mouse)Not determined95780504786121973Mouse
1301702Brm1_mbrachyury modifier 1 (mouse)Not determined94080504774805204Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
10043971Obq32_mobesity QTL 32 (mouse)Not determined93781952871819528Mouse
10043847Hdlq89_mHDL QTL 89 (mouse)Not determined92929292963293072Mouse
10045639Heal28_mwound healing/regeneration 28 (mouse)Not determined94348071477480860Mouse
13525008Hrtiq1_mheart rate time index, QTL 1 (mouse)95242609868556008Mouse
1301965Vmbic5_mventral midbrain iron content 5 (mouse)Not determined95759149265831177Mouse
4141148Cq5_mcholesterol QTL 5 (mouse)Not determined93245242166452546Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95936994693370128Mouse
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
1301365Ap5q_malcohol preference 5 QTL (mouse)Not determined93005316464053277Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96214976796149881Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
1300716Cd4ts4_mCD4 T cell subset 4 (mouse)Not determined94883105682831177Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC142168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC164614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF077950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY902346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000098651   ⟹   ENSMUSP00000096248
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl962,785,650 - 62,888,161 (-)Ensembl
GRCm38.p6 Ensembl962,878,368 - 62,980,879 (-)Ensembl
Ensembl Acc Id: ENSMUST00000214830   ⟹   ENSMUSP00000150834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl962,790,162 - 62,888,165 (-)Ensembl
GRCm38.p6 Ensembl962,882,880 - 62,980,883 (-)Ensembl
Ensembl Acc Id: ENSMUST00000215455
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl962,830,189 - 62,859,278 (-)Ensembl
GRCm38.p6 Ensembl962,922,907 - 62,951,996 (-)Ensembl
Ensembl Acc Id: ENSMUST00000215501   ⟹   ENSMUSP00000149235
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl962,785,769 - 62,794,669 (-)Ensembl
GRCm38.p6 Ensembl962,878,487 - 62,887,387 (-)Ensembl
Ensembl Acc Id: ENSMUST00000216209   ⟹   ENSMUSP00000149590
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl962,827,739 - 62,895,206 (-)Ensembl
GRCm38.p6 Ensembl962,920,457 - 62,987,924 (-)Ensembl
RefSeq Acc Id: NM_019663   ⟹   NP_062637
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39962,787,359 - 62,888,161 (-)NCBI
GRCm38962,880,077 - 62,980,879 (-)NCBI
MGSCv37962,727,884 - 62,828,686 (-)RGD
Celera960,099,154 - 60,199,601 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006511302   ⟹   XP_006511365
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39962,785,648 - 62,861,721 (-)NCBI
GRCm38962,878,366 - 62,953,168 (-)NCBI
Sequence:
RefSeq Acc Id: NP_062637   ⟸   NM_019663
- UniProtKB: O88907 (UniProtKB/Swiss-Prot),   Q8C6H5 (UniProtKB/Swiss-Prot),   Q3U556 (UniProtKB/TrEMBL),   Q2M4G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006511365   ⟸   XM_006511302
- Peptide Label: isoform X1
- UniProtKB: Q3U556 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000149590   ⟸   ENSMUST00000216209
Ensembl Acc Id: ENSMUSP00000096248   ⟸   ENSMUST00000098651
Ensembl Acc Id: ENSMUSP00000149235   ⟸   ENSMUST00000215501
Ensembl Acc Id: ENSMUSP00000150834   ⟸   ENSMUST00000214830
Protein Domains
PINIT   SAP   SP-RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88907-F1-model_v2 AlphaFold O88907 1-651 view protein structure

Promoters
RGD ID:6844949
Promoter ID:MM_KWN:57698
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000116566,   NM_019663
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36962,828,401 - 62,828,901 (-)MPROMDB
RGD ID:8669914
Promoter ID:EPDNEW_M12987
Type:multiple initiation site
Name:Pias1_1
Description:Mus musculus protein inhibitor of activated STAT 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38962,980,883 - 62,980,943EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913125 AgrOrtholog
Ensembl Genes ENSMUSG00000032405 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098651 ENTREZGENE
  ENSMUST00000098651.6 UniProtKB/Swiss-Prot
  ENSMUST00000214830.2 UniProtKB/TrEMBL
  ENSMUST00000215501.2 UniProtKB/TrEMBL
  ENSMUST00000216209.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.720.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.120.780 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PINIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PINIT_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_MIZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56469 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1913125 ENTREZGENE
NCBI Gene 56469 ENTREZGENE
PANTHER PTHR10782:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PINIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-MIZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pias1 PhenoGen
PROSITE PINIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_SP_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF68906 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1SQX9_MOUSE UniProtKB/TrEMBL
  A0A1L1SRS2_MOUSE UniProtKB/TrEMBL
  O88907 ENTREZGENE, UniProtKB/Swiss-Prot
  Q2M4G9 ENTREZGENE, UniProtKB/TrEMBL
  Q3U556 ENTREZGENE, UniProtKB/TrEMBL
  Q3UWQ0_MOUSE UniProtKB/TrEMBL
  Q8C6H5 ENTREZGENE
UniProt Secondary Q8C6H5 UniProtKB/Swiss-Prot