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Gene: PIAS3 (protein inhibitor of activated STAT 3) Homo sapiens
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Symbol: PIAS3
Name: protein inhibitor of activated STAT 3
RGD ID: 1344818
Description: Exhibits SUMO transferase activity; enzyme binding activity; and protein C-terminus binding activity. Involved in negative regulation of protein sumoylation and positive regulation of protein sumoylation. Predicted to localize to nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E3 SUMO-protein ligase PIAS3; E3 SUMO-protein transferase PIAS3; FLJ14651; protein inhibitor of activated STAT protein 3; zinc finger, MIZ-type containing 5; ZMIZ5
Orthologs:
Mus musculus (house mouse) : Pias3 (protein inhibitor of activated STAT 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pias3 (protein inhibitor of activated STAT, 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias3 (protein inhibitor of activated STAT 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS3 (protein inhibitor of activated STAT 3)
Canis lupus familiaris (dog) : PIAS3 (protein inhibitor of activated STAT 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias3 (protein inhibitor of activated STAT 3)
Sus scrofa (pig) : PIAS3 (protein inhibitor of activated STAT 3)
Chlorocebus sabaeus (African green monkey) : PIAS3 (protein inhibitor of activated STAT 3)
Heterocephalus glaber (naked mole-rat) : Pias3 (protein inhibitor of activated STAT 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1145,848,522 - 145,859,836 (-)EnsemblGRCh38hg38GRCh38
GRCh381145,848,522 - 145,859,081 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371145,575,257 - 145,586,546 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,287,345 - 144,297,903 (+)NCBINCBI36hg18NCBI36
Build 341143,065,075 - 143,075,590NCBI
Celera1119,779,357 - 119,789,916 (+)NCBI
Cytogenetic Map1q21.1NCBI
HuRef1119,539,725 - 119,550,284 (+)NCBIHuRef
CHM1_11147,216,648 - 147,227,207 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIAS3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1344818
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.