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Gene: PIAS2 (protein inhibitor of activated STAT 2) Homo sapiens
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Symbol: PIAS2
Name: protein inhibitor of activated STAT 2
RGD ID: 1603704
Description: Exhibits SUMO ligase activity and transcription factor binding activity. Involved in negative regulation of DNA-binding transcription factor activity; negative regulation of androgen receptor signaling pathway; and protein sumoylation. Localizes to nucleoplasm. Colocalizes with PML body.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: androgen receptor-interacting protein 3; ARIP3; DAB2-interacting protein; DIP; E3 SUMO-protein ligase PIAS2; E3 SUMO-protein transferase PIAS2; MGC102682; MIZ; MIZ1; msx-interacting zinc finger protein; Msx-interacting-zinc finger; PIAS-NY protein; PIASX; PIASX-ALPHA; PIASX-BETA; protein inhibitor of activated STAT x; SIZ2; zinc finger, MIZ-type containing 4; ZMIZ4
Orthologs:
Mus musculus (house mouse) : Pias2 (protein inhibitor of activated STAT 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pias2 (protein inhibitor of activated STAT, 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias2 (protein inhibitor of activated STAT 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS2 (protein inhibitor of activated STAT 2)
Canis lupus familiaris (dog) : PIAS2 (protein inhibitor of activated STAT 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias2 (protein inhibitor of activated STAT 2)
Sus scrofa (pig) : PIAS2 (protein inhibitor of activated STAT 2)
Chlorocebus sabaeus (African green monkey) : PIAS2 (protein inhibitor of activated STAT 2)
Heterocephalus glaber (naked mole-rat) : Pias2 (protein inhibitor of activated STAT 2)
more info ...
Related Pseudogenes: AC092593.1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1846,803,218 - 46,920,160 (-)EnsemblGRCh38hg38GRCh38
GRCh381846,803,218 - 46,920,167 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371844,388,900 - 44,500,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361842,646,058 - 42,751,464 (-)NCBINCBI36hg18NCBI36
Celera1841,199,736 - 41,278,688 (-)NCBI
Cytogenetic Map18q21.1NCBI
HuRef1841,247,384 - 41,354,863 (-)NCBIHuRef
CHM1_11844,310,277 - 44,427,236 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PIAS2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603704
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.