Nr2f1 (nuclear receptor subfamily 2, group F, member 1) - Rat Genome Database

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Gene: Nr2f1 (nuclear receptor subfamily 2, group F, member 1) Mus musculus
Analyze
Symbol: Nr2f1
Name: nuclear receptor subfamily 2, group F, member 1
RGD ID: 1317579
MGI Page MGI
Description: Enables sequence-specific DNA binding activity. Acts upstream of or within nervous system development and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and sensory organ. Used to study Bosch-Boonstra-Schaaf optic atrophy syndrome. Human ortholog(s) of this gene implicated in Bosch-Boonstra-Schaaf optic atrophy syndrome. Orthologous to human NR2F1 (nuclear receptor subfamily 2 group F member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: avian erythroblastic leukemia viral (v-erb-a) oncogene homolog-like 3; COUP transcription factor 1; COUP transcription factor I; COUP-; COUP-T; COUP-TF I; COUP-TF1; COUP-TFI; COUPTFA; EAR-3; EAR3; Erb; Erbal3; MGC118474; nuclear receptor subfamily 2 group F member 1; SVP44; Tcfcou; Tcfcoup1; V-erbA-related protein 3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391378,337,090 - 78,346,954 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1378,337,092 - 78,347,876 (-)EnsemblGRCm39 Ensembl
GRCm381378,188,971 - 78,198,873 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1378,188,973 - 78,199,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv371378,328,234 - 78,338,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361378,652,524 - 78,662,420 (-)NCBIMGSCv36mm8
Celera1380,475,542 - 80,485,460 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1341.38NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
antimycin A  (ISO)
arachidonic acid  (ISO)
arotinoid acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[ghi]perylene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bucladesine  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
chlordecone  (EXP)
ciglitazone  (ISO)
cisplatin  (ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
deguelin  (ISO)
dexamethasone  (EXP,ISO)
diallyl trisulfide  (ISO)
dichlorine  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenpyroximate  (ISO)
fructose  (ISO)
geraniol  (ISO)
glucose  (ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
isotretinoin  (ISO)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
L-ascorbic acid 2-phosphate  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
medroxyprogesterone acetate  (ISO)
mercury dibromide  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
pirinixic acid  (EXP,ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
triacsin C  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
XAV939  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anterior commissure morphology  (IAGP)
abnormal auditory brainstem response  (IEA)
abnormal axon guidance  (IAGP)
abnormal axon morphology  (IAGP)
abnormal barrel cortex morphology  (IAGP)
abnormal brain commissure morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal cingulate gyrus morphology  (IAGP)
abnormal cochlear hair cell development  (IAGP)
abnormal cochlear hair cell morphology  (IAGP)
abnormal cochlear inner hair cell morphology  (IAGP)
abnormal cochlear outer hair cell morphology  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal dorsal striatum morphology  (IAGP)
abnormal eye development  (IAGP)
abnormal glossopharyngeal ganglion morphology  (IAGP)
abnormal hearing physiology  (IAGP)
abnormal hippocampal commissure morphology  (IAGP)
abnormal long-term depression  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal optic fissure closure  (IAGP)
abnormal optic stalk morphology  (IAGP)
abnormal organ of Corti supporting cell differentiation  (IAGP)
abnormal orientation of inner hair cell stereociliary bundles  (IAGP)
abnormal orientation of outer hair cell stereociliary bundles  (IAGP)
abnormal primary somatosensory cortex morphology  (IAGP)
abnormal retina pigment epithelium morphology  (IAGP)
abnormal utricular macula morphology  (IAGP)
abnormal vestibular saccular macula morphology  (IAGP)
absent barrels in primary somatosensory cortex  (IAGP)
absent optic disk  (IAGP)
coloboma  (IAGP)
decreased body weight  (IAGP)
decreased grip strength  (IAGP)
decreased hippocampus volume  (IAGP)
decreased startle reflex  (IAGP)
embryonic growth retardation  (IEA)
fused vestibular saccule and utricle  (IAGP)
hypotonia  (IAGP)
impaired hearing  (IAGP)
impaired righting response  (IAGP)
impaired synaptic plasticity  (IAGP)
increased cochlear hair cell number  (IAGP)
increased cochlear inner hair cell number  (IAGP)
increased cochlear outer hair cell number  (IAGP)
increased Deiters cell number  (IAGP)
increased neocortex volume  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
microphthalmia  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
no swallowing reflex  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
persistence of hyaloid vascular system  (IEA)
preweaning lethality, complete penetrance  (IEA)
reduced long-term potentiation  (IAGP)
short scala media  (IAGP)
slow extinction of fear memory  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors. Hamasaki T, etal., Neuron 2004 Aug 5;43(3):359-72.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7609634   PMID:7626501   PMID:7708064   PMID:7823919   PMID:7947324   PMID:8183930   PMID:8314004   PMID:8530078   PMID:8804707   PMID:8873065   PMID:9177236   PMID:9271116  
PMID:9632703   PMID:10349636   PMID:10624948   PMID:10753524   PMID:10922068   PMID:10949085   PMID:11042159   PMID:11076861   PMID:11493561   PMID:11511537   PMID:11784044   PMID:12397111  
PMID:12421703   PMID:12477932   PMID:12619893   PMID:12642494   PMID:12724834   PMID:12872126   PMID:14531791   PMID:14738874   PMID:15213010   PMID:15548577   PMID:15618518   PMID:15677473  
PMID:15705776   PMID:15809042   PMID:15858069   PMID:15907456   PMID:15944189   PMID:16107646   PMID:16141072   PMID:16141073   PMID:16144621   PMID:16219912   PMID:16284245   PMID:16602821  
PMID:16613831   PMID:16914494   PMID:16971476   PMID:16973757   PMID:17021036   PMID:17150988   PMID:17181553   PMID:17205580   PMID:17207666   PMID:17470284   PMID:17804629   PMID:17828260  
PMID:17928865   PMID:18165280   PMID:18177425   PMID:18287559   PMID:18625063   PMID:18701084   PMID:18753373   PMID:18957218   PMID:19030180   PMID:19160499   PMID:19192266   PMID:19386638  
PMID:19449303   PMID:19535498   PMID:19596317   PMID:19766631   PMID:19799774   PMID:19812316   PMID:20007910   PMID:20089898   PMID:20111703   PMID:20133588   PMID:20147377   PMID:20181579  
PMID:20237272   PMID:20412781   PMID:20615956   PMID:20668538   PMID:20797425   PMID:20932939   PMID:21060110   PMID:21060113   PMID:21194568   PMID:21266512   PMID:21267068   PMID:21430164  
PMID:21731673   PMID:21873635   PMID:21965613   PMID:22031906   PMID:22492355   PMID:22623663   PMID:22711520   PMID:22923088   PMID:22988430   PMID:23018522   PMID:23056316   PMID:23307639  
PMID:23375746   PMID:23426374   PMID:23431145   PMID:23472160   PMID:23744949   PMID:23785296   PMID:23975195   PMID:24194600   PMID:24227652   PMID:24324671   PMID:24349493   PMID:24859337  
PMID:24952961   PMID:25182747   PMID:25467980   PMID:25922524   PMID:25971728   PMID:26166575   PMID:26387718   PMID:26671461   PMID:26795843   PMID:26813976   PMID:26814051   PMID:26985665  
PMID:27034423   PMID:27100196   PMID:27178193   PMID:27282384   PMID:27321927   PMID:27585883   PMID:28506990   PMID:28694260   PMID:28706241   PMID:28729440   PMID:29031500   PMID:29205104  
PMID:29513653   PMID:29996095   PMID:30174317   PMID:30217595   PMID:30406191   PMID:30653836   PMID:30846445   PMID:31073041   PMID:31082736   PMID:31257105   PMID:31318166   PMID:31395862  
PMID:31600777   PMID:32421711   PMID:32484994   PMID:32572460   PMID:32737167   PMID:33523829   PMID:34686322   PMID:34921112   PMID:34963132   PMID:35163483   PMID:35175194   PMID:35377797  
PMID:35613264   PMID:36064547   PMID:36596814   PMID:37260288   PMID:37386251   PMID:37532091   PMID:37995181   PMID:38086370   PMID:38355793   PMID:38498715   PMID:39159043  


Genomics

Comparative Map Data
Nr2f1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391378,337,090 - 78,346,954 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1378,337,092 - 78,347,876 (-)EnsemblGRCm39 Ensembl
GRCm381378,188,971 - 78,198,873 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1378,188,973 - 78,199,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv371378,328,234 - 78,338,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361378,652,524 - 78,662,420 (-)NCBIMGSCv36mm8
Celera1380,475,542 - 80,485,460 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1341.38NCBI
NR2F1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38593,583,222 - 93,594,611 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl593,583,222 - 93,594,611 (+)EnsemblGRCh38hg38GRCh38
GRCh37592,918,928 - 92,930,317 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36592,944,799 - 92,955,544 (+)NCBINCBI36Build 36hg18NCBI36
Build 34592,944,798 - 92,955,540NCBI
Celera588,778,440 - 88,789,186 (+)NCBICelera
Cytogenetic Map5q15NCBI
HuRef588,092,169 - 88,102,739 (+)NCBIHuRef
CHM1_1592,351,749 - 92,362,489 (+)NCBICHM1_1
T2T-CHM13v2.0594,067,283 - 94,078,673 (+)NCBIT2T-CHM13v2.0
Nr2f1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr829,776,179 - 9,785,924 (-)NCBIGRCr8
mRatBN7.228,040,375 - 8,050,123 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl28,040,377 - 8,050,123 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx215,156,212 - 15,165,958 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0213,255,522 - 13,265,268 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.027,905,787 - 7,915,533 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.025,569,954 - 5,579,894 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl25,569,935 - 5,579,894 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.025,553,211 - 5,563,152 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.425,765,399 - 5,794,104 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.125,791,963 - 5,820,665 (-)NCBI
Celera24,489,100 - 4,498,590 (-)NCBICelera
Cytogenetic Map2q11NCBI
Nr2f1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541818,614,995 - 18,624,584 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541818,615,548 - 18,622,984 (-)NCBIChiLan1.0ChiLan1.0
NR2F1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2421,798,293 - 21,808,047 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1519,951,902 - 19,964,301 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0521,773,283 - 21,785,746 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1521,909,691 - 21,918,776 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl521,910,463 - 21,918,776 (-)Ensemblpanpan1.1panPan2
NR2F1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1315,707,198 - 15,716,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl315,707,640 - 15,716,875 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha317,056,142 - 17,065,912 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0315,603,857 - 15,613,637 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl315,603,875 - 15,613,542 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1315,559,980 - 15,569,747 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0315,546,214 - 15,555,980 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0315,764,483 - 15,774,264 (-)NCBIUU_Cfam_GSD_1.0
Nr2f1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213171,322,457 - 171,331,829 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365239,507,965 - 9,517,272 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365239,508,204 - 9,517,266 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR2F1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2100,447,705 - 100,457,506 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12100,447,661 - 100,457,510 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22103,839,017 - 103,848,870 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NR2F1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1487,463,514 - 87,475,900 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl487,466,249 - 87,475,112 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604936,657,859 - 36,670,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nr2f1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474312,478,832 - 12,488,458 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474312,479,427 - 12,488,178 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nr2f1
495 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1081
Count of miRNA genes:509
Interacting mature miRNAs:604
Transcripts:ENSMUST00000091458, ENSMUST00000125176, ENSMUST00000127137, ENSMUST00000135284, ENSMUST00000150498
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879495Fexq1_mfear expression QTL 1 (mouse)137826885895836553Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
12880402Emlq1_memotional learning QTL 1 (mouse)137810885896866553Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
1301610Dps1_mdelta power in slow-wave sleep 1 (mouse)Not determined137719586295730894Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse

Markers in Region
Nr2f1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381378,189,846 - 78,189,980UniSTSGRCm38
MGSCv371378,329,107 - 78,329,241UniSTSGRCm37
Celera1380,476,415 - 80,476,549UniSTS
Cytogenetic Map13C1UniSTS
cM Map1345.0UniSTS
cM Map1345.0UniSTS
PMC316414P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381378,195,162 - 78,195,418UniSTSGRCm38
MGSCv371378,334,423 - 78,334,679UniSTSGRCm37
Celera1380,481,731 - 80,481,987UniSTS
Cytogenetic Map13C1UniSTS
cM Map1345.0UniSTS
Nr2f1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C1UniSTS
Nr2f1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C1UniSTS
Nr2f1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381378,189,103 - 78,189,687UniSTSGRCm38
MGSCv371378,328,364 - 78,328,948UniSTSGRCm37
Celera1380,475,672 - 80,476,256UniSTS
Cytogenetic Map13C1UniSTS
Nr2f1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C1UniSTS
cM Map1345.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001347538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001403777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA230392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA253879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC048695 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC108408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FO706373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000091458   ⟹   ENSMUSP00000089036
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1378,337,092 - 78,347,876 (-)Ensembl
GRCm38.p6 Ensembl1378,188,973 - 78,199,757 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125176   ⟹   ENSMUSP00000122618
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1378,337,852 - 78,344,492 (-)Ensembl
GRCm38.p6 Ensembl1378,189,733 - 78,196,373 (-)Ensembl
Ensembl Acc Id: ENSMUST00000127137   ⟹   ENSMUSP00000133704
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1378,337,791 - 78,346,049 (-)Ensembl
GRCm38.p6 Ensembl1378,189,672 - 78,197,930 (-)Ensembl
Ensembl Acc Id: ENSMUST00000135284
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1378,337,991 - 78,338,562 (-)Ensembl
GRCm38.p6 Ensembl1378,189,872 - 78,190,443 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150498   ⟹   ENSMUSP00000118161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1378,337,271 - 78,345,157 (-)Ensembl
GRCm38.p6 Ensembl1378,189,152 - 78,197,038 (-)Ensembl
Ensembl Acc Id: ENSMUST00000224798   ⟹   ENSMUSP00000153321
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1378,343,537 - 78,345,663 (-)Ensembl
GRCm38.p6 Ensembl1378,195,418 - 78,197,544 (-)Ensembl
RefSeq Acc Id: NM_001347538   ⟹   NP_001334467
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,092 - 78,344,602 (-)NCBI
GRCm381378,188,973 - 78,196,449 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001347539   ⟹   NP_001334468
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,092 - 78,344,602 (-)NCBI
GRCm381378,188,973 - 78,196,449 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001403773   ⟹   NP_001390702
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,092 - 78,346,016 (-)NCBI
RefSeq Acc Id: NM_001403775   ⟹   NP_001390704
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,092 - 78,346,016 (-)NCBI
RefSeq Acc Id: NM_001403777   ⟹   NP_001390706
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,092 - 78,346,016 (-)NCBI
RefSeq Acc Id: NM_010151   ⟹   NP_034281
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,092 - 78,346,954 (-)NCBI
GRCm381378,188,973 - 78,198,873 (-)NCBI
MGSCv371378,328,234 - 78,338,243 (-)RGD
Celera1380,475,542 - 80,485,460 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006517085   ⟹   XP_006517148
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391378,337,090 - 78,346,794 (-)NCBI
GRCm381378,188,971 - 78,198,675 (-)NCBI
Sequence:
RefSeq Acc Id: NP_034281   ⟸   NM_010151
- Peptide Label: isoform a
- UniProtKB: Q61438 (UniProtKB/Swiss-Prot),   Q60632 (UniProtKB/Swiss-Prot),   Q32NY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517148   ⟸   XM_006517085
- Peptide Label: isoform X1
- UniProtKB: Q61438 (UniProtKB/Swiss-Prot),   Q60632 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001334467   ⟸   NM_001347538
- Peptide Label: isoform b
- UniProtKB: F7CII1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001334468   ⟸   NM_001347539
- Peptide Label: isoform c
- UniProtKB: B8JJI9 (UniProtKB/TrEMBL),   G3UXI5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000122618   ⟸   ENSMUST00000125176
Ensembl Acc Id: ENSMUSP00000089036   ⟸   ENSMUST00000091458
Ensembl Acc Id: ENSMUSP00000118161   ⟸   ENSMUST00000150498
Ensembl Acc Id: ENSMUSP00000133704   ⟸   ENSMUST00000127137
Ensembl Acc Id: ENSMUSP00000153321   ⟸   ENSMUST00000224798
RefSeq Acc Id: NP_001390702   ⟸   NM_001403773
- Peptide Label: isoform b
- UniProtKB: F7CII1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390706   ⟸   NM_001403777
- Peptide Label: isoform b
- UniProtKB: F7CII1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001390704   ⟸   NM_001403775
- Peptide Label: isoform b
- UniProtKB: F7CII1 (UniProtKB/TrEMBL)
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q60632-F1-model_v2 AlphaFold Q60632 1-422 view protein structure

Promoters
RGD ID:8680888
Promoter ID:EPDNEW_M18475
Type:single initiation site
Name:Nr2f1_1
Description:Mus musculus nuclear receptor subfamily 2, group F, member 1, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381378,199,042 - 78,199,102EPDNEW
RGD ID:6824199
Promoter ID:MM_KWN:14763
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000082823
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361378,330,076 - 78,330,576 (-)MPROMDB
RGD ID:6824198
Promoter ID:MM_KWN:14766
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   Brain
Transcripts:OTTMUST00000055749,   OTTMUST00000082822
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361378,339,494 - 78,339,994 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1352451 AgrOrtholog
Ensembl Genes ENSMUSG00000069171 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000091458 ENTREZGENE
  ENSMUST00000091458.13 UniProtKB/TrEMBL
  ENSMUST00000125176 ENTREZGENE
  ENSMUST00000125176.3 UniProtKB/TrEMBL
  ENSMUST00000127137.3 UniProtKB/TrEMBL
  ENSMUST00000150498 ENTREZGENE
  ENSMUST00000150498.8 UniProtKB/TrEMBL
  ENSMUST00000224798.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hormone_rcpt_NR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13865 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1352451 ENTREZGENE
NCBI Gene 13865 ENTREZGENE
PANTHER COUP TRANSCRIPTION FACTOR 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nr2f1 PhenoGen
PRINTS COUPTNFACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286YD96_MOUSE UniProtKB/TrEMBL
  B8JJI9 ENTREZGENE, UniProtKB/TrEMBL
  COT1_MOUSE UniProtKB/Swiss-Prot
  F7CII1 ENTREZGENE, UniProtKB/TrEMBL
  G3UXI5 ENTREZGENE
  Q32NY6 ENTREZGENE, UniProtKB/TrEMBL
  Q3UF74_MOUSE UniProtKB/TrEMBL
  Q60632 ENTREZGENE
  Q61438 ENTREZGENE
UniProt Secondary G3UXI5 UniProtKB/TrEMBL
  Q61438 UniProtKB/Swiss-Prot