Egr4 (early growth response 4) - Rat Genome Database

Name: Egr4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Egr4 (early growth response 4) Mus musculus

Analyze

Symbol:

Egr4

Name:

early growth response 4

RGD ID:

735818

MGI Page

MGI

Description:

Is expressed in several structures, including central nervous system; genitourinary system; and tooth. Orthologous to human EGR4 (early growth response 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

early growth response protein 4; EGR-4; NGF1-; NGF1-C; NGFI; NGFI-C; NGFIC; pAT1; pAT133

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EGR4 (early growth response 4)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Egr4 (early growth response 4)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Egr4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EGR4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EGR4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Egr4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EGR4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	EGR4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Egr4 (early growth response 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Egr4 (early growth response 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	EGR4 (early growth response 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	egr4 (early growth response 4)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|Roundup\|TreeFam)
Caenorhabditis elegans (roundworm):	egrh-1	Alliance	DIOPT (Ensembl Compara\|PANTHER\|Roundup)

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	85,488,103 - 85,490,571 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	85,488,103 - 85,490,571 (-)	Ensembl
GRCm38	6	85,511,121 - 85,513,589 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	85,511,121 - 85,513,589 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	85,461,116 - 85,463,536 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	85,476,780 - 85,479,200 (-)	NCBI			mm8
Celera	6	87,483,061 - 87,485,363 (-)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	37.48	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

middle cerebral artery infarction (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trimethylbenzene (ISO)

1-naphthyl isothiocyanate (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,4-methylenedioxymethamphetamine (EXP)

6-propyl-2-thiouracil (ISO)

acetylsalicylic acid (ISO)

aflatoxin B1 (ISO)

ammonium chloride (ISO)

aripiprazole (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

carbon nanotube (EXP)

carbonyl sulfide (ISO)

cocaine (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclophosphamide (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

decabromodiphenyl ether (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (EXP)

fenvalerate (ISO)

fluoxetine (ISO)

glycidol (ISO)

hydrogen peroxide (ISO)

hydrogen sulfide (EXP)

ketamine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (ISO)

maneb (EXP)

methamphetamine (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

morphine (EXP,ISO)

naphthalenes (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

paraquat (EXP)

pentanal (ISO)

phorbol 13-acetate 12-myristate (ISO)

potassium bromate (EXP)

Ptaquiloside (EXP)

pyridaben (EXP)

quercetin (ISO)

rifampicin (ISO)

SB 431542 (ISO)

SCH 23390 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

Soman (ISO)

tributylstannane (ISO)

trimellitic anhydride (EXP)

undecane (ISO)

valproic acid (ISO)

vinclozolin (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to growth factor stimulus (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

metal ion binding (IEA)

nucleic acid binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal male germ cell apoptosis (IAGP)

abnormal male meiosis (IAGP)

abnormal seminiferous tubule epithelium morphology (IAGP)

abnormal seminiferous tubule morphology (IAGP)

abnormal sperm flagellum morphology (IAGP)

abnormal sperm head morphology (IAGP)

abnormal spermatogenesis (IAGP)

coiled sperm flagellum (IAGP)

decreased heart weight (IEA)

decreased male germ cell number (IAGP)

decreased spleen weight (IEA)

decreased testis weight (IAGP)

detached sperm flagellum (IAGP)

increased Leydig cell number (IAGP)

kinked sperm flagellum (IAGP)

male infertility (IAGP)

oligozoospermia (IAGP)

small testis (IAGP)

teratozoospermia (IAGP)

thrombocytosis (IEA)

References

References - curated


1.	Crosby SD, etal., Proc Natl Acad Sci U S A 1992 May 15;89(10):4739-43.
2.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
3.	Mengozzi M, etal., Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9617-22. doi: 10.1073/pnas.1200554109. Epub 2012 May 29.
4.	MGD and Homologene mouse data transfer
5.	MGD data from the GO Consortium
6.	MGD IEA
7.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8.	RGD automated import pipeline
9.	RGD automated import pipeline for gene-chemical interactions
10.	Swaroop A, etal., Hum Mol Genet 1994 Aug;3(8):1281-6.

Additional References at PubMed

PMID:7774940	PMID:8188273	PMID:8504297	PMID:8751373	PMID:8889548	PMID:9858769	PMID:10349636	PMID:10529423	PMID:10866682	PMID:11042159	PMID:11076861	PMID:11180801
PMID:11217851	PMID:11891986	PMID:12648095	PMID:16141072	PMID:16141073	PMID:17192429	PMID:18287559	PMID:19741146	PMID:20059953	PMID:20925118	PMID:21228173	PMID:21267068
PMID:21837281	PMID:21873635

Genomics

Comparative Map Data

Egr4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	85,488,103 - 85,490,571 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	85,488,103 - 85,490,571 (-)	Ensembl
GRCm38	6	85,511,121 - 85,513,589 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	85,511,121 - 85,513,589 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	85,461,116 - 85,463,536 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	85,476,780 - 85,479,200 (-)	NCBI			mm8
Celera	6	87,483,061 - 87,485,363 (-)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	37.48	NCBI

EGR4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	73,290,929 - 73,293,701 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	73,290,929 - 73,293,548 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	73,518,057 - 73,520,676 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	73,371,565 - 73,374,181 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	73,429,720 - 73,432,265	NCBI
Celera	2	73,368,884 - 73,371,656 (-)	NCBI
Cytogenetic Map	2	p13.2	NCBI
HuRef	2	73,253,506 - 73,256,278 (-)	NCBI		HuRef
CHM1_1	2	73,448,863 - 73,451,635 (-)	NCBI		CHM1_1

Egr4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	118,047,869 - 118,050,328 (-)	NCBI
Rnor_6.0 Ensembl	4	117,293,620 - 117,296,082 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	4	117,293,620 - 117,296,082 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	181,870,041 - 181,872,503 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	119,765,289 - 119,767,612 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	120,009,769 - 120,012,093 (-)	NCBI
Celera	4	107,029,479 - 107,031,938 (-)	NCBI		Celera
RH 3.4 Map	4	690.8	RGD
Cytogenetic Map	4	q34	NCBI

Egr4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	12,338,979 - 12,342,078 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	12,339,152 - 12,341,925 (+)	NCBI	ChiLan1.0	ChiLan1.0

EGR4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	74,831,326 - 74,834,246 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	74,831,326 - 74,834,246 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	73,343,705 - 73,346,476 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

EGR4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	17	49,575,466 - 49,578,251 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	17	49,575,964 - 49,580,697 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Egr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936491	17,068,797 - 17,071,608 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EGR4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	69,486,079 - 69,491,595 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	69,485,919 - 69,488,788 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	72,688,741 - 72,691,610 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EGR4
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	33,879,707 - 33,882,669 (+)	NCBI
ChlSab1.1 Ensembl	14	33,879,904 - 33,882,663 (+)	Ensembl

Egr4
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624762	351,190 - 354,004 (+)	NCBI

Position Markers

RH94566

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	85,511,170 - 85,511,308	UniSTS	GRCm38
MGSCv37	6	85,461,164 - 85,461,302	UniSTS	GRCm37
Celera	6	87,483,109 - 87,483,247	UniSTS
Cytogenetic Map	6	C3	UniSTS
cM Map	6	36.5	UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	1	117500000	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139100000	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87426034	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96656149	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96656149	Mouse
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96656149	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96656149	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38669625	92607450	Mouse
1300618	Pgia19_m	proteoglycan induced arthritis 19 (mouse)			Not determined		6	45314059	87426034	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45314059	128835032	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46935985	136423692	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48720000	125360000	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48720000	148450000	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48726556	125356785	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52161713	116155267	Mouse
4141028	Mclr_m	methylcholanthrene lymphoma resistance (mouse)			Not determined			54373427	88379171	Mouse
15039373	Adip28_m	adiposity 28 (mouse)					6	56308211	90308211	Mouse
15039375	Bw41_m	body weight QTL 41 (mouse)					6	56308211	90308211	Mouse
1558977	Skmw10_m	skeletal muscle weight 10 (mouse)			Not determined		6	58447583	92447710	Mouse
10043972	Obq28_m	obesity QTL 28 (mouse)			Not determined		6	58540433	92540433	Mouse
1301740	Bwq2_m	body weight QTL 2 (mouse)			Not determined		6	60057680	94057799	Mouse
1301369	Im4_m	immunoregulatory 4 (mouse)			Not determined		6	63484738	97484905	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66713869	100714031	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70425898	104426034	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70425898	104426034	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70425898	104426034	Mouse
4141990	Etax6_m	ethanol induced ataxia 6 (mouse)			Not determined			71322621	86275719	Mouse
1302020	Bbaa20_m	B.burgdorferi-associated arthritis 20 (mouse)			Not determined		6	71322621	93464093	Mouse
1300869	Stheal5_m	soft tissue heal 5 (mouse)			Not determined		6	71575060	105575178	Mouse
1300954	Fcsa1_m	femoral cross-sectional area 1 (mouse)			Not determined		6	71981024	105981170	Mouse
1301521	Pas1c_m	pulmonary adenoma susceptibility 1c (mouse)			Not determined		6	71981024	105981170	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73500000	134700000	Mouse
1301320	Ots1_m	ovarian teratoma susceptibility 1 (mouse)			Not determined		6	75447583	104503555	Mouse
1301571	Arrd1_m	age-related retinal degeneration 1 (mouse)			Not determined		6	75544356	92607450	Mouse
1300674	Nidd3n_m	non-insulin-dependent diabetes mellitus 3 in NSY (mouse)			Not determined		6	75544356	94225955	Mouse
10412195	Efw_m	epididymal fat weight (mouse)			Not determined		6	75544356	94225955	Mouse
10043901	Pfat5_m	predicted fat percentage 5 (mouse)			Not determined		6	75607306	109607450	Mouse
10412208	Cypr4_m	cytokine production 4 (mouse)			Not determined		6	75716503	109716697	Mouse
1357875	Pfat2_m	predicted fat percentage 2 (mouse)			Not determined		6	76463949	110464093	Mouse
14697704	Stsl4_m	Salmonella typhimurium susceptibility locus 4 (mouse)					6	77100000	90000000	Mouse
13824985	Alh1_m	amplitude of lateral head displacement 1 (mouse)					6	78000000	97000000	Mouse
4141376	Dbm1_m	diabetes modifier 1 (mouse)			Not determined		6	78629504	121115387	Mouse
14696731	Pairq1_m	P. aeruginosa infection resistance QTL 1 (mouse)					6	81500000	102200000	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83713869	147052561	Mouse
11251720	Ewc4_m	ethanol withdrawal and consumption 4 (mouse)					6	84122513	118122513	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	277
Count of miRNA genes:	215
Interacting mature miRNAs:	238
Transcripts:	ENSMUST00000095759
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_020596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC104743	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF132613	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK141637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX528200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000095759 ⟹ ENSMUSP00000093433

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	85,511,121 - 85,513,589 (-)	Ensembl

RefSeq Acc Id:

NM_020596 ⟹ NP_065621

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	85,488,103 - 85,490,571 (-)	NCBI
GRCm38	6	85,511,121 - 85,513,589 (-)	NCBI
MGSCv37	6	85,461,116 - 85,463,536 (-)	RGD
Celera	6	87,483,061 - 87,485,363 (-)	NCBI
cM Map	6		ENTREZGENE

Sequence:

show sequence

GAGCCCTGTTGCACTTTGGAGAAGCCAGGAGCCGCCACCCGAGGCAGGTGCCGGTGAGCCAGGG
CGCCGCGGCCCCCCAACCCTCGTGCCCCAGCCAAGCGCCCGGAGCCTGGAACTGGGGCGCCCGG
ATTCCCTGCCAGCCGCGCGCGCCCCAGTCCAGCGAGGCCCCGGGCGCCCCGCCGCCACCGCGCC
ATGCTCCACCTGAGCGACTTCTCCGGCTCCGACGCGCTTCTCTCCAAGCCCACCGAAGGCTGCG
CCCACGCCAGCCCCGAGCTGCCCCGGCTGCCTGCTAGGGACGCTCCCTCGGCCGCCGCGTATCC
TGGAGGCGACTTCTTGAGCTGGGCTTTGAGCAGCTGCGGCGCCGGGGGGGACTTAACAGACTCC
TGCTTCCTGGAGGGCCCTGCACCCACGCCCCCTTCGGGCCTCAGCTACAGCGGCAGCTTCTTCA
TCCAGGCGGTTCCCGAACACCCGCACGACCCGGAGGCCCTCTTCAACCTCATGTCTGGCATCTT
GGGCCTGGCACCCTTCCCCGGTCCCGAGGCGGCAGCGTCTCGGTCCCCCCTGGATGTCCCTTTC
CCCGCGGGCCCCGATGCCTTGCTGCCGGACCTCTACTCCCCAGATCTGAGTTCGGCCGCCTTTC
CGGAGGCGTTTTGGGAGGCAGCGCCTTCGGCGGGCGCTCCCTCGCAGTGCCTGTTCGAGCCCCA
GCTCTCCCCGCCCGACGTCAAGCCAGGGCTGCGGGCGCCTCCCGCTTCGCCAGCGCTGGACGCT
GCTGCTTCAGCCTTCAAAGGGCCCTATGCCCCCTGGGAGCTGCTGTCGGCCGGGGTCCCGGGGA
ACTGTGGGTCGCAGGGGAGCTTCCAGACCACCCCGGAGGCCCGCTTCTCTGCAGTAGGGACCAA
GGTCGAGGACCTGCTGTCCATCAGCTGCCCCGCCGAGCTGCCCGGCCCGGCCGCCAGACTCTAC
CAGGCAGGGGCCTACGACACCTTCTCGTTGGCCCCAGGTGACTTAGGGGAGGGGACCGAGGGCC
TCCCGGCGCTGCTGACCCCTCCCGGCGGGGAGGGAGGGAGCGGCGGCGAAGGCGGAGAGTTCCT
GGCCGCCCCTCCGGCGCAGCTGTCCCCTCTAGGCCTGCGCGGTGCCGCCACGGCGGACTTCTCC
AAACCCCTGGTGGCCGATCTCCCGGGGGGCAGCGGCGTGGCCGCGCCCTCATCCCCCGCCGCAT
CCTTCCCCGCGGCCAAAGCCCGACGCAAGGGACGCCGGGGCGGCAAGTGCAGCGCGCGCTGCTT
CTGCCCGCGGCCGCACGTCAAGGCCTTCGCCTGCCCGGTGGAGAGCTGCGTGCGGAGCTTCGCG
CGCTCCGACGAGCTCAACCGCCACCTGCGCATCCACACGGGCCACAAGCCCTTCCAGTGCCGCA
TCTGCCTGCGCAACTTCAGCCGCAGCGACCACCTCACCACGCACGTGCGCACCCACACGGGCGA
GAAGCCCTTCGCCTGCGACGTGTGTGGCCGCCGCTTCGCGCGCAGTGACGAGAAGAAACGGCAC
AGCAAGGTGCACCTAAAGCAGAAGGCGCGCGCGGAGGAGCGCCTCAAGGGCCTGGGCTTCTACT
CGCTGGGCCTCTCCTTCGCCGCGCTGTAACCGGAGCTGGCCCCGTAGGTCGGGGGCGCCGGGTG
CTCGGCGCACGCGGCACGGTCCGGCCGGTCCCTCGTTCCCCGCTGCCCTCCCTGCCTCTTCCAC
GCACGTCCGGGGCCACCCGCAGTCCAGCTCCAGTTTCCCCCGAAGCGCCCGCCGCTCACGCCCT
TCAGCACGGGTTCCGCGGACAGCGCCCGCTGTTCGGGAGCCGCCTTCCTCCAGCCAGCCTCTCT
GGGGACAGTCCTCTCGGTCCACCCACAGAACAGGCACTTCCTTGGGACTGAAGAAAGTGTTTTT
GTAACTGGCGTACGCCCCACGCCTTCCTCTTTATCCCTCCCCAGAGACAAGCTGGGGATGTACC
GAGCCGGTCTCTTAAGAACTTTGTACAGCAAGTCTTTGGATGTGATGTTTTTGCTTTGGGGTTA
TTTCCTTTTTGTTGTTCATTTTTTGTAAAGCAGACGCTACTCTCAAGCATTTGACAAAACTGTT
TATTTTTGCAATTAAAATTATTGTGCTAAAAGCTTAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_065621	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD28267	(Get FASTA)	NCBI Sequence Viewer
	BAE24779	(Get FASTA)	NCBI Sequence Viewer
	EDK99137	(Get FASTA)	NCBI Sequence Viewer
	Q9WUF2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_065621 ⟸ NM_020596

- UniProtKB:

Q9WUF2 (UniProtKB/Swiss-Prot), Q3URA9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLHLSDFSGSDALLSKPTEGCAHASPELPRLPARDAPSAAAYPGGDFLSWALSSCGAGGDLTDS
CFLEGPAPTPPSGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDVPF
PAGPDALLPDLYSPDLSSAAFPEAFWEAAPSAGAPSQCLFEPQLSPPDVKPGLRAPPASPALDA
AASAFKGPYAPWELLSAGVPGNCGSQGSFQTTPEARFSAVGTKVEDLLSISCPAELPGPAARLY
QAGAYDTFSLAPGDLGEGTEGLPALLTPPGGEGGSGGEGGEFLAAPPAQLSPLGLRGAATADFS
KPLVADLPGGSGVAAPSSPAASFPAAKARRKGRRGGKCSARCFCPRPHVKAFACPVESCVRSFA
RSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRH
SKVHLKQKARAEERLKGLGFYSLGLSFAAL

hide sequence

RefSeq Acc Id:

ENSMUSP00000093433 ⟸ ENSMUST00000095759

Protein Domains

C2H2-type

Promoters

RGD ID:

6839216

Promoter ID:

MM_KWN:46687

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

ENSMUST00000095759

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	85,463,471 - 85,463,971 (-)	MPROMDB

RGD ID:

6890236

Promoter ID:

EPDNEW_M8569

Type:

single initiation site

Name:

Egr4_1

Description:

Mus musculus early growth response 4 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	85,513,588 - 85,513,648	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:99252	AgrOrtholog
Ensembl Genes	ENSMUSG00000068300
	ENSMUSG00000071341	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000093433	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000095759	ENTREZGENE, UniProtKB/Swiss-Prot
InterPro	Znf_C2H2_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:13656	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:99252	ENTREZGENE
NCBI Gene	13656	ENTREZGENE
Pfam	zf-C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Egr4	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	EGR4_MOUSE	UniProtKB/Swiss-Prot
	Q3URA9	ENTREZGENE, UniProtKB/TrEMBL
	Q9WUF2	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)