Ryr1 Mouse 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of RYR1 mRNA CTD PMID:22206623 Ryr1 Mouse 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of RYR1 mRNA CTD PMID:19484750 Ryr1 Mouse 2,2',3,3',6,6'-hexachlorobiphenyl multiple interactions ISO RYR1 (Homo sapiens) 6480464 [RYR1 protein co-treated with 2 more ... CTD PMID:18954145 Ryr1 Mouse 2,2',3,3',6,6'-hexachlorobiphenyl multiple interactions EXP 6480464 2 more ... CTD PMID:18954145 Ryr1 Mouse 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RYR1 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 Ryr1 Mouse 2,2',5,5'-tetrachlorobiphenyl increases expression ISO Ryr1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:23829299 Ryr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RYR1 protein] CTD PMID:18172213 and PMID:18172886 Ryr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ryr1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of RYR1 mRNA CTD PMID:32109520 Ryr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ryr1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of RYR1 protein CTD PMID:31511937 Ryr1 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RYR1 mRNA and Tetrachlorodibenzodioxin results in increased expression of RYR1 protein CTD PMID:18172213 and PMID:18172886 Ryr1 Mouse 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 Ryr1 Mouse 2,4,6-tribromophenol decreases expression ISO RYR1 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 Ryr1 Mouse 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Ryr1 (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of RYR1 mRNA CTD PMID:23537331 Ryr1 Mouse 3,3',5,5'-tetrabromobisphenol A increases activity EXP 6480464 tetrabromobisphenol A results in increased activity of RYR1 protein CTD PMID:18329244 Ryr1 Mouse 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP 6480464 Tetracaine inhibits the reaction [tetrabromobisphenol A results in increased activity of RYR1 protein] CTD PMID:18329244 Ryr1 Mouse 4,4'-sulfonyldiphenol decreases methylation ISO RYR1 (Homo sapiens) 6480464 bisphenol S results in decreased methylation of RYR1 gene CTD PMID:31601247 Ryr1 Mouse 4,4'-sulfonyldiphenol affects methylation EXP 6480464 bisphenol S affects the methylation of RYR1 gene CTD PMID:31683443 Ryr1 Mouse 4-chloro-m-cresol increases response to substance ISO RYR1 (Homo sapiens) 6480464 RYR1 gene mutant form results in increased susceptibility to chlorocresol more ... CTD PMID:12810058 more ... Ryr1 Mouse 4-chloro-m-cresol increases activity ISO RYR1 (Homo sapiens) 6480464 chlorocresol results in increased activity of RYR1 protein CTD PMID:17707769 and PMID:21485675 Ryr1 Mouse 4-chloro-m-cresol affects response to substance ISO RYR1 (Homo sapiens) 6480464 RYR1 protein alternative form affects the susceptibility to chlorocresol CTD PMID:19191333 Ryr1 Mouse 4-chloro-m-cresol multiple interactions ISO RYR1 (Homo sapiens) 6480464 [chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein] more ... CTD PMID:16372898 more ... Ryr1 Mouse 5-aza-2'-deoxycytidine multiple interactions ISO RYR1 (Homo sapiens) 6480464 Decitabine inhibits the reaction [Smoke results in decreased expression of RYR1 mRNA] CTD PMID:21095227 Ryr1 Mouse acrylamide decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of RYR1 mRNA CTD PMID:28606764 Ryr1 Mouse aflatoxin B1 affects methylation ISO RYR1 (Homo sapiens) 6480464 Aflatoxin B1 affects the methylation of RYR1 intron CTD PMID:30157460 Ryr1 Mouse Aflatoxin B2 alpha decreases methylation ISO RYR1 (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of RYR1 intron CTD PMID:30157460 Ryr1 Mouse alpha-Zearalanol decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Zeranol results in decreased expression of RYR1 mRNA CTD PMID:35163327 Ryr1 Mouse alpha-Zearalanol multiple interactions ISO Ryr1 (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RYR1 mRNA CTD PMID:35163327 Ryr1 Mouse ammonium chloride affects expression ISO Ryr1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of RYR1 mRNA CTD PMID:16483693 Ryr1 Mouse Ammothamnine increases expression ISO RYR1 (Homo sapiens) 6480464 oxymatrine results in increased expression of RYR1 mRNA CTD PMID:33241020 Ryr1 Mouse Ammothamnine multiple interactions ISO RYR1 (Homo sapiens) 6480464 oxymatrine promotes the reaction [sodium arsenite results in increased expression of RYR1 mRNA] CTD PMID:33241020 Ryr1 Mouse Aroclor 1254 increases expression ISO Ryr1 (Rattus norvegicus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of RYR1 protein CTD PMID:16309888 and PMID:19337518 Ryr1 Mouse arsane multiple interactions ISO RYR1 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of RYR1 mRNA CTD PMID:32525701 Ryr1 Mouse arsenic atom multiple interactions ISO RYR1 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of RYR1 mRNA CTD PMID:32525701 Ryr1 Mouse arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of RYR1 mRNA CTD PMID:33053406 Ryr1 Mouse atrazine increases expression ISO RYR1 (Homo sapiens) 6480464 Atrazine results in increased expression of RYR1 mRNA CTD PMID:22378314 Ryr1 Mouse atrazine affects methylation ISO Ryr1 (Rattus norvegicus) 6480464 Atrazine affects the methylation of RYR1 gene CTD PMID:35440735 Ryr1 Mouse baclofen multiple interactions EXP 6480464 Baclofen inhibits the reaction [A 68930 results in increased expression of RYR1 protein] and Baclofen inhibits the reaction [SK&F 82958 results in increased expression of RYR1 protein] CTD PMID:22504960 Ryr1 Mouse benzalkonium chloride multiple interactions EXP 6480464 [IL6 protein affects the susceptibility to Benzalkonium Compounds] which affects the expression of RYR1 mRNA CTD PMID:30171875 Ryr1 Mouse benzo[a]pyrene multiple interactions EXP 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RYR1 mRNA] CTD PMID:22228805 Ryr1 Mouse benzo[a]pyrene affects methylation ISO RYR1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of RYR1 intron and Benzo(a)pyrene affects the methylation of RYR1 promoter CTD PMID:27901495 and PMID:30157460 Ryr1 Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RYR1 mRNA CTD PMID:22228805 Ryr1 Mouse benzo[e]pyrene increases methylation ISO RYR1 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of RYR1 exon and benzo(e)pyrene results in increased methylation of RYR1 intron CTD PMID:30157460 Ryr1 Mouse bicuculline increases response to substance ISO Ryr1 (Rattus norvegicus) 6480464 RYR1 results in increased susceptibility to Bicuculline CTD PMID:22534176 Ryr1 Mouse bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of RYR1 mRNA CTD PMID:28085963 Ryr1 Mouse bisphenol A decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of RYR1 mRNA CTD PMID:27178563 Ryr1 Mouse bisphenol A decreases expression ISO RYR1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of RYR1 protein CTD PMID:31675489 Ryr1 Mouse bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RYR1 mRNA CTD PMID:26063408 and PMID:30951980 Ryr1 Mouse cadmium atom increases expression ISO RYR1 (Homo sapiens) 6480464 Cadmium results in increased expression of RYR1 mRNA CTD PMID:21120746 Ryr1 Mouse cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of RYR1 mRNA CTD PMID:24982889 Ryr1 Mouse caffeine multiple interactions EXP 6480464 TRPC3 protein affects the reaction [Caffeine results in increased activity of RYR1 protein] CTD PMID:16484216 Ryr1 Mouse caffeine increases response to substance ISO RYR1 (Homo sapiens) 6480464 RYR1 gene mutant form results in increased susceptibility to Caffeine and RYR1 protein mutant form results in increased susceptibility to Caffeine CTD PMID:14641996 more ... Ryr1 Mouse caffeine increases activity ISO RYR1 (Homo sapiens) 6480464 Caffeine results in increased activity of RYR1 protein CTD PMID:21485675 Ryr1 Mouse caffeine multiple interactions ISO RYR1 (Homo sapiens) 6480464 [Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium and RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium] CTD PMID:16372898 and PMID:21485675 Ryr1 Mouse caffeine increases activity EXP 6480464 Caffeine results in increased activity of RYR1 protein CTD PMID:16484216 Ryr1 Mouse calcium atom multiple interactions ISO Ryr1 (Rattus norvegicus) 6480464 Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein] and Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein] CTD PMID:15628869 Ryr1 Mouse calcium atom affects abundance ISO RYR1 (Homo sapiens) 6480464 RYR1 protein polymorphism affects the abundance of Calcium CTD PMID:16372898 Ryr1 Mouse calcium atom increases secretion ISO RYR1 (Homo sapiens) 6480464 RYR1 protein mutant form results in increased secretion of Calcium CTD PMID:18719443 Ryr1 Mouse calcium atom increases abundance ISO RYR1 (Homo sapiens) 6480464 RYR1 gene mutant form results in increased abundance of Calcium CTD PMID:19191329 Ryr1 Mouse calcium atom multiple interactions ISO RYR1 (Homo sapiens) 6480464 [Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium more ... CTD PMID:15381065 more ... Ryr1 Mouse calcium(0) multiple interactions ISO Ryr1 (Rattus norvegicus) 6480464 Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein] and Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein] CTD PMID:15628869 Ryr1 Mouse calcium(0) affects abundance ISO RYR1 (Homo sapiens) 6480464 RYR1 protein polymorphism affects the abundance of Calcium CTD PMID:16372898 Ryr1 Mouse calcium(0) increases abundance ISO RYR1 (Homo sapiens) 6480464 RYR1 gene mutant form results in increased abundance of Calcium CTD PMID:19191329 Ryr1 Mouse calcium(0) increases secretion ISO RYR1 (Homo sapiens) 6480464 RYR1 protein mutant form results in increased secretion of Calcium CTD PMID:18719443 Ryr1 Mouse calcium(0) multiple interactions ISO RYR1 (Homo sapiens) 6480464 [Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium more ... CTD PMID:15381065 more ... Ryr1 Mouse CGP 52608 multiple interactions ISO RYR1 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to RYR1 gene] CTD PMID:28238834 Ryr1 Mouse chlordecone decreases expression EXP 6480464 Chlordecone results in decreased expression of RYR1 mRNA CTD PMID:33711761 Ryr1 Mouse chlorpyrifos decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of RYR1 mRNA CTD PMID:31879696 Ryr1 Mouse chlorpyrifos increases expression ISO Ryr1 (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of RYR1 mRNA CTD PMID:32289335 Ryr1 Mouse chlorpyrifos multiple interactions ISO Ryr1 (Rattus norvegicus) 6480464 [Chlorpyrifos co-treated with Dietary Fats] results in increased expression of RYR1 mRNA CTD PMID:32289335 Ryr1 Mouse choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RYR1 mRNA CTD PMID:20938992 Ryr1 Mouse chrysene increases expression EXP 6480464 chrysene results in increased expression of RYR1 mRNA CTD PMID:26377693 Ryr1 Mouse Cuprizon decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Cuprizone results in decreased expression of RYR1 mRNA CTD PMID:26577399 Ryr1 Mouse dantrolene multiple interactions ISO RYR1 (Homo sapiens) 6480464 Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]] and Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium] CTD PMID:17707769 Ryr1 Mouse DDE affects activity ISO RYR1 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene affects the activity of RYR1 protein CTD PMID:31127943 Ryr1 Mouse DDT affects activity ISO RYR1 (Homo sapiens) 6480464 DDT affects the activity of RYR1 protein CTD PMID:31127943 Ryr1 Mouse decabromodiphenyl ether decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in decreased expression of RYR1 mRNA CTD PMID:23640034 Ryr1 Mouse decabromodiphenyl ether decreases expression ISO RYR1 (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of RYR1 protein CTD PMID:31675489 Ryr1 Mouse dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RYR1 mRNA CTD PMID:29950665 Ryr1 Mouse dimethylarsinic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of RYR1 mRNA CTD PMID:34876320 Ryr1 Mouse dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate decreases expression ISO RYR1 (Homo sapiens) 6480464 Antimony Potassium Tartrate results in decreased expression of RYR1 mRNA CTD PMID:28713220 Ryr1 Mouse ethanol increases expression EXP 6480464 Ethanol results in increased expression of RYR1 mRNA CTD PMID:30319688 Ryr1 Mouse fenvalerate decreases expression EXP 6480464 fenvalerate results in decreased expression of RYR1 mRNA CTD PMID:19428952 Ryr1 Mouse flubendiamide multiple interactions EXP 6480464 flubendiamide promotes the reaction [Ryanodine binds to RYR1 protein] CTD PMID:30329129 Ryr1 Mouse folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RYR1 mRNA CTD PMID:20938992 Ryr1 Mouse graphite increases expression EXP 6480464 Graphite results in increased expression of RYR1 mRNA CTD PMID:27440207 Ryr1 Mouse halothane multiple interactions ISO RYR1 (Homo sapiens) 6480464 [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium CTD PMID:21485675 Ryr1 Mouse halothane increases expression EXP 6480464 Halothane results in increased expression of RYR1 mRNA CTD PMID:32795494 Ryr1 Mouse halothane increases response to substance ISO RYR1 (Homo sapiens) 6480464 RYR1 protein mutant form results in increased susceptibility to Halothane CTD PMID:14641996 and PMID:15210166 Ryr1 Mouse halothane increases activity ISO RYR1 (Homo sapiens) 6480464 Halothane results in increased activity of RYR1 protein CTD PMID:21485675 Ryr1 Mouse L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of RYR1 mRNA CTD PMID:20938992 Ryr1 Mouse leflunomide decreases expression EXP 6480464 leflunomide results in decreased expression of RYR1 mRNA CTD PMID:19751817 Ryr1 Mouse lipopolysaccharide multiple interactions ISO RYR1 (Homo sapiens) 6480464 [chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein] and Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]] CTD PMID:17707769 Ryr1 Mouse menadione affects expression ISO RYR1 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of RYR1 mRNA CTD PMID:20044591 Ryr1 Mouse methapyrilene increases methylation ISO RYR1 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of RYR1 exon and Methapyrilene results in increased methylation of RYR1 intron CTD PMID:30157460 Ryr1 Mouse methoxychlor affects methylation ISO Ryr1 (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of RYR1 gene CTD PMID:35440735 Ryr1 Mouse methylarsonic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of RYR1 mRNA CTD PMID:34876320 Ryr1 Mouse mono(2-ethylhexyl) phthalate decreases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of RYR1 mRNA CTD PMID:22401849 Ryr1 Mouse N-methyl-4-phenylpyridinium increases expression ISO RYR1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of RYR1 mRNA CTD PMID:24810058 Ryr1 Mouse Nor-9-carboxy-delta9-THC multiple interactions ISO RYR1 (Homo sapiens) 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of RYR1 gene CTD PMID:30521419 Ryr1 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of RYR1 mRNA CTD PMID:17562736 Ryr1 Mouse perfluorooctanoic acid decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased expression of RYR1 mRNA CTD PMID:16221955 Ryr1 Mouse perfluorooctanoic acid increases expression ISO Ryr1 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of RYR1 mRNA CTD PMID:35163327 Ryr1 Mouse perfluorooctanoic acid multiple interactions ISO Ryr1 (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RYR1 mRNA CTD PMID:35163327 Ryr1 Mouse pioglitazone multiple interactions EXP 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RYR1 mRNA CTD PMID:27935865 Ryr1 Mouse raloxifene affects expression ISO RYR1 (Homo sapiens) 6480464 Raloxifene Hydrochloride affects the expression of RYR1 mRNA CTD PMID:14699072 Ryr1 Mouse ryanodine multiple interactions ISO RYR1 (Homo sapiens) 6480464 Triclosan promotes the reaction [Ryanodine binds to RYR1 protein] CTD PMID:18795164 Ryr1 Mouse ryanodine multiple interactions EXP 6480464 2 more ... CTD PMID:18954145 and PMID:30329129 Ryr1 Mouse SCH 23390 multiple interactions EXP 6480464 SCH 23390 inhibits the reaction [SK&F 82958 results in increased expression of RYR1 protein] CTD PMID:22504960 Ryr1 Mouse silicon dioxide decreases expression ISO RYR1 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of RYR1 mRNA CTD PMID:25895662 Ryr1 Mouse sodium arsenate multiple interactions ISO RYR1 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of RYR1 mRNA CTD PMID:32525701 Ryr1 Mouse sodium arsenate multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of RYR1 mRNA CTD PMID:34876320 Ryr1 Mouse sodium arsenite decreases expression ISO RYR1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of RYR1 mRNA CTD PMID:28713220 and PMID:34032870 Ryr1 Mouse sodium arsenite multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of RYR1 mRNA CTD PMID:34876320 Ryr1 Mouse sodium arsenite increases expression ISO RYR1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of RYR1 mRNA CTD PMID:33241020 and PMID:38568856 Ryr1 Mouse sodium arsenite multiple interactions ISO RYR1 (Homo sapiens) 6480464 oxymatrine promotes the reaction [sodium arsenite results in increased expression of RYR1 mRNA] CTD PMID:33241020 Ryr1 Mouse Soman decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Soman results in decreased expression of RYR1 mRNA CTD PMID:19281266 Ryr1 Mouse sotorasib multiple interactions ISO RYR1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RYR1 mRNA CTD PMID:36139627 Ryr1 Mouse spermine increases expression EXP 6480464 Spermine results in increased expression of RYR1 mRNA CTD PMID:18673383 Ryr1 Mouse tacrolimus hydrate multiple interactions EXP 6480464 Tacrolimus inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RYR1 protein] CTD PMID:18172213 and PMID:18172886 Ryr1 Mouse tamoxifen affects expression ISO RYR1 (Homo sapiens) 6480464 Tamoxifen affects the expression of RYR1 mRNA CTD PMID:14699072 Ryr1 Mouse tetracaine multiple interactions EXP 6480464 Tetracaine inhibits the reaction [tetrabromobisphenol A results in increased activity of RYR1 protein] CTD PMID:18329244 Ryr1 Mouse titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of RYR1 mRNA CTD PMID:29950665 Ryr1 Mouse titanium dioxide decreases methylation EXP 6480464 titanium dioxide results in decreased methylation of RYR1 gene CTD PMID:35295148 Ryr1 Mouse trametinib multiple interactions ISO RYR1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RYR1 mRNA CTD PMID:36139627 Ryr1 Mouse trichloroethene increases expression ISO Ryr1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of RYR1 mRNA CTD PMID:33387578 Ryr1 Mouse triclosan multiple interactions ISO RYR1 (Homo sapiens) 6480464 Triclosan promotes the reaction [Ryanodine binds to RYR1 protein] CTD PMID:18795164 Ryr1 Mouse triclosan decreases expression ISO RYR1 (Homo sapiens) 6480464 Triclosan results in decreased expression of RYR1 mRNA CTD PMID:30510588 Ryr1 Mouse triptonide increases expression EXP 6480464 triptonide results in increased expression of RYR1 mRNA CTD PMID:33045310 Ryr1 Mouse valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of RYR1 mRNA CTD PMID:21427059 Ryr1 Mouse valproic acid decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of RYR1 mRNA CTD PMID:29427782 Ryr1 Mouse vorinostat decreases expression ISO RYR1 (Homo sapiens) 6480464 vorinostat results in decreased expression of RYR1 mRNA CTD PMID:18769122 Ryr1 Mouse zinc atom decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of RYR1 mRNA CTD PMID:19111725 Ryr1 Mouse zinc(0) decreases expression ISO Ryr1 (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of RYR1 mRNA CTD PMID:19111725