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Gene: Itga6 (integrin alpha 6) Mus musculus
Symbol: Itga6
Name: integrin alpha 6
RGD ID: 731430
Description: Exhibits integrin binding activity. Involved in several processes, including brown fat cell differentiation; cell adhesion mediated by integrin; and filopodium assembly. Localizes to several cellular components, including basal plasma membrane; external side of plasma membrane; and hemidesmosome. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study junctional epidermolysis bullosa Herlitz type. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGA6 (integrin subunit alpha 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5033401O05Rik; AI115430; CD49 antigen-like family member F; Cd49f; integrin alpha-6; VLA-6
Homo sapiens (human) : ITGA6 (integrin subunit alpha 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itga6 (integrin subunit alpha 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga6 (integrin subunit alpha 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA6 (integrin subunit alpha 6)
Canis lupus familiaris (dog) : ITGA6 (integrin subunit alpha 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga6 (integrin subunit alpha 6)
Sus scrofa (pig) : ITGA6 (integrin subunit alpha 6)
Chlorocebus sabaeus (African green monkey) : ITGA6 (integrin subunit alpha 6)
Heterocephalus glaber (naked mole-rat) : Itga6 (integrin subunit alpha 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39271,617,236 - 71,688,771 (+)NCBI
GRCm38271,786,886 - 71,858,427 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,745,616 - 71,858,416 (+)EnsemblGRCm38mm10GRCm38
MGSCv37271,625,140 - 71,694,815 (+)NCBIGRCm37mm9NCBIm37
MGSCv36271,587,922 - 71,657,597 (+)NCBImm8
Celera273,459,136 - 73,529,018 (+)NCBICelera
Cytogenetic Map2C2- C3NCBI
cM Map242.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Itga6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731430
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-11-03
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.