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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733768
Species: Mus musculus
RGD Object: Gene
Symbol: Lss
Name: lanosterol synthase
Acc ID: CHEBI:144441
Term: triacsin C
Definition: A nitroso compound that is N-undecylnitrous hydrazide carrying double bonds at positions 1,2,4, and 7. It is a long-chain fatty acyl CoA synthetase inhibitor and interferes with lipid metabolism by inhibiting the de novo synthesis of glycerolipids and cholesterol esters.
Chemical ID: MESH:C034613
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lssdecreases expressionISOLSS (Homo sapiens)6480464CTDtriacsin C results in decreased expression of LSS mRNAPMID:16704987
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