Ddb1 (damage specific DNA binding protein 1) - Rat Genome Database

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Gene: Ddb1 (damage specific DNA binding protein 1) Mus musculus
Analyze
Symbol: Ddb1
Name: damage specific DNA binding protein 1
RGD ID: 734017
MGI Page MGI
Description: Predicted to enable several functions, including WD40-repeat domain binding activity; cullin family protein binding activity; and ubiquitin ligase complex scaffold activity. Involved in several processes, including cellular response to UV; positive regulation of gluconeogenesis; and ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including Wnt signaling pathway; negative regulation of apoptotic process; and negative regulation of reproductive process. Part of Cul4A-RING E3 ubiquitin ligase complex. Is expressed in several structures, including blastocyst; early embryo; germ cell of gonad; otocyst; and spleen. Human ortholog(s) of this gene implicated in communication disorder. Orthologous to human DDB1 (damage specific DNA binding protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 127kDa; AA408517; damage-specific DNA-binding protein 1; damage-specific DNA-binding protein, DNA repair; damaged-DNA recognition protein 1; DDB p127 subunit; DNA damage-binding protein 1; DNA repair protein; p127-Ddb; p127-Ddb1; UV-damaged DNA-binding factor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,582,961 - 10,607,186 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,582,691 - 10,607,183 (+)EnsemblGRCm39 Ensembl
GRCm381910,605,568 - 10,629,828 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,605,327 - 10,629,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv371910,680,115 - 10,704,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,672,670 - 10,696,867 (+)NCBIMGSCv36mm8
Celera1911,301,601 - 11,325,808 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
amphibole asbestos  (ISO)
antimony trichloride  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
clobetasol  (EXP)
clofibric acid  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
D-glucitol  (EXP)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
ethanol  (EXP)
folic acid  (EXP)
fulvestrant  (ISO)
fumonisin B1  (EXP)
gentamycin  (ISO)
ivermectin  (ISO)
ketoconazole  (ISO)
L-methionine  (EXP)
lenalidomide  (ISO)
lipopolysaccharide  (ISO)
miconazole  (EXP)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
nicotine  (ISO)
Nutlin-3  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP)
thalidomide  (EXP)
thapsigargin  (EXP)
thiram  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
undecane  (ISO)
usnic acid  (ISO)
vinclozolin  (ISO)
zinc pyrithione  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. TFIIH: when transcription met DNA repair. Compe E and Egly JM, Nat Rev Mol Cell Biol. 2012 May 10;13(6):343-54. doi: 10.1038/nrm3350.
2. Nucleotide excision repair: new tricks with old bricks. Kamileri I, etal., Trends Genet. 2012 Nov;28(11):566-73. doi: 10.1016/j.tig.2012.06.004. Epub 2012 Jul 22.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Mutation burden analysis of six common mental disorders in African Americans by whole genome sequencing. Liu Y, etal., Hum Mol Genet. 2022 Nov 10;31(22):3769-3776. doi: 10.1093/hmg/ddac129.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization. Powles N, etal., Dev Biol 2004 Apr 1;268(1):24-38.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9530637   PMID:10349636   PMID:10574459   PMID:10713455   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11172053   PMID:12107171   PMID:12477932   PMID:12520002   PMID:12904583  
PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17041588   PMID:17129780   PMID:17301228   PMID:17967808   PMID:17967871   PMID:18799693   PMID:18936169  
PMID:19056892   PMID:20059953   PMID:20360068   PMID:20362542   PMID:21135245   PMID:21267068   PMID:21565611   PMID:21677750   PMID:21698215   PMID:21873635   PMID:22118460   PMID:22384083  
PMID:23297343   PMID:24357321   PMID:24457600   PMID:24845235   PMID:24855944   PMID:25371539   PMID:25970626   PMID:26150517   PMID:26281983   PMID:26323038   PMID:26431207   PMID:26496610  
PMID:26584622   PMID:26613412   PMID:27065194   PMID:27113764   PMID:27123980   PMID:27325702   PMID:27471256   PMID:28178526   PMID:28378742   PMID:28623141   PMID:28671696   PMID:28790135  
PMID:28818995   PMID:29370161   PMID:30111536   PMID:30196744   PMID:30333137   PMID:30442713   PMID:30550785   PMID:31492966   PMID:31598710   PMID:31779270   PMID:32094118   PMID:32098917  
PMID:32246987   PMID:32299058   PMID:32325033   PMID:32434143   PMID:32479761   PMID:32554809   PMID:33127885   PMID:33524014   PMID:33634103   PMID:34161765   PMID:34526995   PMID:36114006  
PMID:37142655   PMID:37839992   PMID:38355793   PMID:38934719  


Genomics

Comparative Map Data
Ddb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391910,582,961 - 10,607,186 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1910,582,691 - 10,607,183 (+)EnsemblGRCm39 Ensembl
GRCm381910,605,568 - 10,629,828 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1910,605,327 - 10,629,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv371910,680,115 - 10,704,312 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361910,672,670 - 10,696,867 (+)NCBIMGSCv36mm8
Celera1911,301,601 - 11,325,808 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map196.66NCBI
DDB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,299,451 - 61,333,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,299,451 - 61,342,596 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,066,923 - 61,100,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361160,823,495 - 60,857,242 (-)NCBINCBI36Build 36hg18NCBI36
Build 341160,823,499 - 60,857,125NCBI
Cytogenetic Map11q12.2NCBI
HuRef1157,394,763 - 57,428,510 (-)NCBIHuRef
CHM1_11160,949,958 - 60,983,704 (-)NCBICHM1_1
T2T-CHM13v2.01161,288,439 - 61,322,058 (-)NCBIT2T-CHM13v2.0
Ddb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81216,677,810 - 216,703,605 (+)NCBIGRCr8
mRatBN7.21207,252,890 - 207,278,685 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1207,252,890 - 207,278,676 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1215,631,459 - 215,657,329 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,687,016 - 222,712,802 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01215,382,012 - 215,407,798 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01226,657,561 - 226,683,356 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1226,657,561 - 226,683,347 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01233,603,490 - 233,629,285 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41213,095,187 - 213,120,986 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1204,746,264 - 204,772,059 (+)NCBICelera
Cytogenetic Map1q43NCBI
Ddb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555116,209,777 - 6,233,594 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555116,209,777 - 6,233,594 (+)NCBIChiLan1.0ChiLan1.0
DDB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2962,467,451 - 62,501,152 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,511,126 - 63,544,583 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01156,599,422 - 56,633,140 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,964,235 - 59,997,805 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,964,235 - 59,997,805 (-)Ensemblpanpan1.1panPan2
DDB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11855,064,720 - 55,097,623 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1855,064,729 - 55,097,627 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1853,637,465 - 53,670,146 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01856,112,716 - 56,145,419 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1856,112,714 - 56,167,311 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11855,170,743 - 55,203,394 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01854,792,588 - 54,825,289 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01855,673,233 - 55,706,147 (+)NCBIUU_Cfam_GSD_1.0
Ddb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494711,596,653 - 11,628,774 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365811,710,382 - 1,742,598 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365811,710,382 - 1,742,598 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl210,171,502 - 10,201,598 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1210,171,554 - 10,201,602 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.229,718,733 - 9,748,620 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,508,712 - 12,543,127 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,508,443 - 12,544,913 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038109,887,958 - 109,922,218 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624926871,000 - 897,777 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624926871,003 - 893,902 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ddb1
733 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:289
Count of miRNA genes:205
Interacting mature miRNAs:239
Transcripts:ENSMUST00000025649
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
38455997Cdtm2_mCD62L+ CD8 TM cells 2 (mouse)19997736419977364Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse

Markers in Region
RH135781  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381910,629,095 - 10,629,243UniSTSGRCm38
MGSCv371910,703,585 - 10,703,733UniSTSGRCm37
Celera1911,325,081 - 11,325,229UniSTS
Cytogenetic Map19centromereUniSTS
cM Map195.0UniSTS
RH124722  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381910,629,467 - 10,629,606UniSTSGRCm38
MGSCv371910,703,957 - 10,704,096UniSTSGRCm37
Celera1911,325,453 - 11,325,592UniSTS
Cytogenetic Map19centromereUniSTS
cM Map195.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001410219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_015735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB026432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC125093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF159853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ416426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK004284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC002210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000025649   ⟹   ENSMUSP00000025649
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,582,691 - 10,607,183 (+)Ensembl
GRCm38.p6 Ensembl1910,605,327 - 10,629,819 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236279
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,603,967 - 10,606,698 (+)Ensembl
GRCm38.p6 Ensembl1910,626,603 - 10,629,334 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236280   ⟹   ENSMUSP00000158020
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,582,951 - 10,592,954 (+)Ensembl
GRCm38.p6 Ensembl1910,605,587 - 10,615,590 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236328   ⟹   ENSMUSP00000158549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,592,229 - 10,599,303 (+)Ensembl
GRCm38.p6 Ensembl1910,614,865 - 10,621,939 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236596
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,592,238 - 10,593,172 (+)Ensembl
GRCm38.p6 Ensembl1910,614,874 - 10,615,808 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236722
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,583,074 - 10,587,324 (+)Ensembl
GRCm38.p6 Ensembl1910,605,710 - 10,609,960 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236937
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,602,411 - 10,603,602 (+)Ensembl
GRCm38.p6 Ensembl1910,625,047 - 10,626,238 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237138
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,587,785 - 10,592,332 (+)Ensembl
GRCm38.p6 Ensembl1910,610,421 - 10,614,968 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,583,706 - 10,585,833 (+)Ensembl
GRCm38.p6 Ensembl1910,606,342 - 10,608,469 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237337   ⟹   ENSMUSP00000157538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,582,987 - 10,606,676 (+)Ensembl
GRCm38.p6 Ensembl1910,605,623 - 10,629,312 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237804
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1910,596,358 - 10,599,509 (+)Ensembl
GRCm38.p6 Ensembl1910,618,994 - 10,622,145 (+)Ensembl
RefSeq Acc Id: NM_001410219   ⟹   NP_001397148
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,582,961 - 10,607,186 (+)NCBI
RefSeq Acc Id: NM_015735   ⟹   NP_056550
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391910,582,961 - 10,607,186 (+)NCBI
GRCm381910,605,597 - 10,629,828 (+)NCBI
MGSCv371910,680,115 - 10,704,312 (+)RGD
Celera1911,301,601 - 11,325,808 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_056550   ⟸   NM_015735
- Peptide Label: isoform 2
- UniProtKB: Q9QYK0 (UniProtKB/Swiss-Prot),   Q99LV3 (UniProtKB/Swiss-Prot),   Q3UJC4 (UniProtKB/Swiss-Prot),   Q3U8G3 (UniProtKB/Swiss-Prot),   Q3U4D0 (UniProtKB/Swiss-Prot),   Q9WV39 (UniProtKB/Swiss-Prot),   Q3U1J4 (UniProtKB/Swiss-Prot),   Q91YC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000157538   ⟸   ENSMUST00000237337
Ensembl Acc Id: ENSMUSP00000158549   ⟸   ENSMUST00000236328
Ensembl Acc Id: ENSMUSP00000158020   ⟸   ENSMUST00000236280
Ensembl Acc Id: ENSMUSP00000025649   ⟸   ENSMUST00000025649
RefSeq Acc Id: NP_001397148   ⟸   NM_001410219
- Peptide Label: isoform 1
- UniProtKB: Q91YC8 (UniProtKB/TrEMBL)
Protein Domains
Cleavage/polyadenylation specificity factor A

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3U1J4-F1-model_v2 AlphaFold Q3U1J4 1-1140 view protein structure

Promoters
RGD ID:13678918
Promoter ID:EPDNEW_M23608
Type:initiation region
Name:Ddb1_1
Description:Mus musculus damage specific DNA binding protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381910,605,636 - 10,605,696EPDNEW
RGD ID:6829967
Promoter ID:MM_KWN:26387
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000025649,   ENSMUST00000113082,   UC008GQK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361910,679,826 - 10,680,562 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1202384 AgrOrtholog
Ensembl Genes ENSMUSG00000024740 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025649 ENTREZGENE
  ENSMUST00000025649.10 UniProtKB/Swiss-Prot
  ENSMUST00000236280.2 UniProtKB/TrEMBL
  ENSMUST00000236328.2 UniProtKB/TrEMBL
  ENSMUST00000237337.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.910 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cleavage/polyA-sp_fac_asu_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cleavage/polyA-sp_fac_asu_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Quinoprotein_ADH-like_supfam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RSE1/DDB1/CFT1/CPSF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report mmu:13194 UniProtKB/Swiss-Prot
MGD MGI:1202384 ENTREZGENE
NCBI Gene 13194 ENTREZGENE
PANTHER DNA REPAIR/RNA PROCESSING CPSF FAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10644:SF3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CPSF_A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MMS1_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ddb1 PhenoGen
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
  SSF50998 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A494B987_MOUSE UniProtKB/TrEMBL
  A0A494BAF6_MOUSE UniProtKB/TrEMBL
  A0A494BBJ6_MOUSE UniProtKB/TrEMBL
  DDB1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U4D0 ENTREZGENE
  Q3U8G3 ENTREZGENE
  Q3UJC4 ENTREZGENE
  Q3ULS8_MOUSE UniProtKB/TrEMBL
  Q91YC8 ENTREZGENE, UniProtKB/TrEMBL
  Q99LV3 ENTREZGENE
  Q9QYK0 ENTREZGENE
  Q9WV39 ENTREZGENE
UniProt Secondary Q3U4D0 UniProtKB/Swiss-Prot
  Q3U8G3 UniProtKB/Swiss-Prot
  Q3UJC4 UniProtKB/Swiss-Prot
  Q99LV3 UniProtKB/Swiss-Prot
  Q9QYK0 UniProtKB/Swiss-Prot
  Q9WV39 UniProtKB/Swiss-Prot