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Gene: Mir15b (microRNA 15b) Mus musculus
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Symbol: Mir15b
Name: microRNA 15b
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: mir-15b; Mirn15b; mmu-mir-15b
Orthologs:
Homo sapiens (human) : MIR15B (microRNA 15b)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mir15b (microRNA 15b)  Alliance
Canis lupus familiaris (dog) : MIR15B (microRNA mir-15b)
Sus scrofa (pig) : MIR15B (microRNA mir-15b)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38369,009,772 - 69,009,835 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37368,813,694 - 68,813,757 (+)NCBIGRCm37mm9NCBIm37
Celera369,117,586 - 69,117,649 (+)NCBICelera
Cytogenetic Map3 E1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences

Additional Information

External Database Links
 
More on Mir15b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1608316
Created: 2007-04-29
Species: Mus musculus
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.