Mirlet7e (microRNA let7e) - Rat Genome Database
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Gene: Mirlet7e (microRNA let7e) Mus musculus
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Symbol: Mirlet7e
Name: microRNA let7e
RGD ID: 1607640
MGI Page MGI
Description: Is expressed in brain and embryo. Orthologous to human MIRLET7E (microRNA let-7e).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mirnl; Mirnlet7e; mmu-let-7; mmu-let-7e
RGD Orthologs
Human
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391718,050,614 - 18,050,706 (+)NCBIGRCm39mm39
GRCm39 Ensembl1718,050,614 - 18,050,706 (+)Ensembl
GRCm381717,830,352 - 17,830,444 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1717,830,352 - 17,830,444 (+)EnsemblGRCm38mm10GRCm38
MGSCv371717,967,316 - 17,967,408 (+)NCBIGRCm37mm9NCBIm37
Celera1718,771,003 - 18,771,095 (+)NCBICelera
Cytogenetic Map17A3.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:12007417   PMID:15361871   PMID:15538371   PMID:15845075   PMID:16381832   PMID:16766679   PMID:17369397   PMID:17604727   PMID:18452032   PMID:18723672   PMID:18791161   PMID:19898466  
PMID:19949436   PMID:20215419   PMID:20413612   PMID:20439489   PMID:20660734   PMID:20668074   PMID:21267068   PMID:21430230   PMID:23079871   PMID:23200853   PMID:23593353   PMID:23622242  
PMID:23895693   PMID:24503540   PMID:25858512   PMID:26107383   PMID:26139524   PMID:28049690   PMID:28298326   PMID:28710810   PMID:29770701   PMID:30530288   PMID:30555476   PMID:30635573  
PMID:31682635   PMID:31733402   PMID:31905402  


Genomics

Comparative Map Data
Mirlet7e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391718,050,614 - 18,050,706 (+)NCBIGRCm39mm39
GRCm39 Ensembl1718,050,614 - 18,050,706 (+)Ensembl
GRCm381717,830,352 - 17,830,444 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1717,830,352 - 17,830,444 (+)EnsemblGRCm38mm10GRCm38
MGSCv371717,967,316 - 17,967,408 (+)NCBIGRCm37mm9NCBIm37
Celera1718,771,003 - 18,771,095 (+)NCBICelera
Cytogenetic Map17A3.2NCBI
MIRLET7E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1951,692,786 - 51,692,864 (+)EnsemblGRCh38hg38GRCh38
GRCh381951,692,786 - 51,692,864 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371952,196,039 - 52,196,117 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,887,850 - 56,887,928 (+)NCBINCBI36hg18NCBI36
Celera1949,245,574 - 49,245,652 (+)NCBI
Cytogenetic Map19q13.41NCBI
HuRef1948,526,980 - 48,527,058 (+)NCBIHuRef
CHM1_11952,197,836 - 52,197,914 (+)NCBICHM1_1
MIRLET7E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1105,400,730 - 105,400,816 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11105,400,740 - 105,400,806 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIRLET7E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl658,332,036 - 58,332,120 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1658,332,042 - 58,332,121 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,858,376 - 51,858,455 (+)NCBISscrofa10.2Sscrofa10.2susScr3


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17126862710Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171241779526182159Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120924747Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171661519333600869Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17128979566Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17392461526182159Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17126862710Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17125975624Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125443244Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17480447727496965Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120924747Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17765701129268449Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1197944224857795Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17130809908Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17128979566Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17128979566Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17125970523Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Eif3j1mmu-let-7e-5pMirtarbaseexternal_infoReporter assayNon-Functional MTI15131085
Tlr4mmu-let-7e-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCRFunctional MTI19699171
Trim71mmu-let-7e-5pMirtarbaseexternal_infoFlow//GFP reporter assay//Immunocytochemistry//ImmFunctional MTI19898466
Eif3j1mmu-let-7e-5pTarbaseexternal_infoReporter GeneNEGATIVE
Tlr4mmu-let-7e-5pMirecordsexternal_info{changed}NA19699171
Pak1mmu-let-7e-5pOncomiRDBexternal_infoNANA23339187
Hmga2mmu-let-7e-5pOncomiRDBexternal_infoNANA23318420
Mycnmmu-let-7e-5pOncomiRDBexternal_infoNANA23042116
Has2mmu-let-7e-5pOncomiRDBexternal_infoNANA22871741
Ezh2mmu-let-7e-5pOncomiRDBexternal_infoNANA22442719
Ccnd1mmu-let-7e-5pOncomiRDBexternal_infoNANA21969366
Mycnmmu-let-7e-5pOncomiRDBexternal_infoNANA21654684
Fasmmu-let-7e-5pOncomiRDBexternal_infoNANA21530489
Lin28ammu-let-7e-5pOncomiRDBexternal_infoNANA21045151
Esr1mmu-let-7e-5pOncomiRDBexternal_infoNANA20535543
Nol3mmu-let-7e-5pOncomiRDBexternal_infoNANA20525879
Il6mmu-let-7e-5pOncomiRDBexternal_infoNANA19878981
Hmga2mmu-let-7e-5pOncomiRDBexternal_infoNANA19153603
Dicer1mmu-let-7e-5pOncomiRDBexternal_infoNANA18700235
Hmga2mmu-let-7e-5pOncomiRDBexternal_infoNANA18403645
Hmga2mmu-let-7e-5pOncomiRDBexternal_infoNANA17600087
Hmga2mmu-let-7e-5pOncomiRDBexternal_infoNANA17437991
Hmga2mmu-let-7e-5pOncomiRDBexternal_infoNANA17322030
Krasmmu-let-7e-5pOncomiRDBexternal_infoNANA15766527

Predicted Targets
Summary Value
Count of predictions:24116
Count of gene targets:9700
Count of transcripts:16068
Interacting mature miRNAs:mmu-let-7e-3p, mmu-let-7e-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000196737
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1717,830,352 - 17,830,444 (+)Ensembl
RefSeq Acc Id: NR_029730
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391718,050,614 - 18,050,706 (+)NCBI
GRCm381717,830,352 - 17,830,444 (+)ENTREZGENE
MGSCv371717,967,316 - 17,967,408 (+)RGD
Celera1718,771,003 - 18,771,095 (+)RGD
cM Map17 ENTREZGENE
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676797 AgrOrtholog
Ensembl Genes ENSMUSG00000105758 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000196737 ENTREZGENE
MGD MGI:2676797 ENTREZGENE
miRBase MI0000561 ENTREZGENE
NCBI Gene 387248 ENTREZGENE
PhenoGen Mirlet7e PhenoGen
RNAcentral URS000000B1C9 RNACentral
  URS0000409B45 RNACentral
  URS000075CDF6 RNACentral