Gene: Foxp1 (forkhead box P1) Mus musculus
Analyze
Symbol:
Foxp1
Name:
forkhead box P1
Description:
Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein dimerization activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; esophagus adenocarcinoma; intellectual disability-severe speech delay-mild dysmorphism syndrome; peritonitis; and schizophrenia. Is expressed in several structures, including brain; branchial arch; embryo mesenchyme; genitourinary system; and musculoskeletal system. Orthologous to human FOXP1 (forkhead box P1); INTERACTS WITH (S)-nicotine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
3110052D19Rik; 4932443N09Rik; AI461938; AW494214; forkhead box protein P1; forkhead-related transcription factor 1
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
FOXP1 (forkhead box P1) HGNC
EggNOG, Ensembl, HGNC, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):
Foxp1 (forkhead box P1) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Foxp1 (forkhead box P1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
FOXP1 (forkhead box P1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
FOXP1 (forkhead box P1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Foxp1 (forkhead box P1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
FOXP1 (forkhead box P1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
FOXP4 (forkhead box P4) HGNC
OrthoMCL
Homo sapiens (human):
FOXP2 (forkhead box P2) HGNC
OrthoMCL
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Foxp1 (forkhead box P1)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
FOXP1 (forkhead box P1)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
foxp1a (forkhead box P1a)
Alliance
DIOPT (OrthoFinder, PANTHER, PhylomeDB, TreeFam, ZFIN)
Danio rerio (zebrafish):
foxp1b (forkhead box P1b)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, Roundup, TreeFam, ZFIN)
Caenorhabditis elegans (roundworm):
fkh-7
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Drosophila melanogaster (fruit fly):
FoxP
Alliance
DIOPT (Ensembl Compara, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 6 98,925,342 - 99,522,746 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 6 98,880,084 - 99,113,012 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 6 98,895,553 - 99,128,481 (-) NCBI mm8 Celera 6 100,788,270 - 101,299,156 (-) NCBI Celera Cytogenetic Map 6 D3 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
atrioventricular septal defect ISO RGD:1318576 8554872 ClinVar Annotator: match by term: AVC DEFECT ClinVar PMID:23766104 , PMID:25741868 autistic disorder ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Autism ClinVar autistic disorder ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Autistic disorder of childhood onset ClinVar PMID:25741868 Endocardial Cushion Defects ISO RGD:1318576 8554872 ClinVar Annotator: match by term: ENDOCARDIAL CUSHION DEFECT ClinVar PMID:23766104 , PMID:25741868 epilepsy ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Seizures ClinVar PMID:25741868 genetic disease ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:12692134 more ... genetic disease ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:12692134 more ... genetic disease ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:12692134 more ... hypoplastic left heart syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Hypoplastic left heart syndrome ClinVar PMID:23766104 , PMID:25741868 Hypoplastic Left Heart Syndrome 1 ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Hypoplastic left heart syndrome 1 ClinVar PMID:23766104 , PMID:25741868 intellectual disability ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation ClinVar PMID:25741868 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by OMIM:613670 ClinVar PMID:26647308 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Intellectual Disability with Language Impairment and Autistic Features ClinVar PMID:20848658 more ... intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Intellectual Disability with Language Impairment and Autistic Features ClinVar PMID:18414213 more ... intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Intellectual Disability with Language Impairment and Autistic Features ClinVar PMID:23766104 , PMID:25741868 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:25326635 , PMID:25741868 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:12692134 more ... intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:12692134 more ... intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:25741868 , PMID:28708303 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:20950788 , PMID:26647308 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:25131622 , PMID:26647308 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by OMIM:613670 ClinVar intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Mental retardation with language impairment and with or without autistic features ClinVar PMID:23757202 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by OMIM:613670 ClinVar PMID:20950788 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by OMIM:613670 ClinVar PMID:24214399 intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 8554872 ClinVar Annotator: match by OMIM:613670 ClinVar PMID:25741868 Language Development Disorders ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Speech delay ClinVar PMID:25741868 Pulmonary Atresia with Ventricular Septal Defect ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Pulmonary atresia with ventricular septal defect ClinVar PMID:23766104 , PMID:25741868 strabismus ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Squint ClinVar PMID:25741868 visceral heterotaxy ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Heterotaxia ClinVar PMID:23766104 , PMID:25741868 visual epilepsy ISO RGD:1318576 8554872 ClinVar Annotator: match by term: Seizures ClinVar PMID:25741868
Imported Annotations - CTD
autism spectrum disorder ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21572417 esophagus adenocarcinoma ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:24121790 juvenile rheumatoid arthritis ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19565504 Lymphatic Metastasis ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25485836 Neoplasm Invasiveness ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25485836 Neurodevelopmental Disorders ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28191889 pancreatic cancer ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25485836 vitiligo ISO RGD:1318576 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:20526340 Imported Annotations - OMIM
intellectual disability-severe speech delay-mild dysmorphism syndrome ISO RGD:1318576 7240710 OMIM
(+)-catechin multiple interactions ISO RGD:1318576 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of FOXP1 mRNA CTD PMID:24763279 (-)-demecolcine increases expression ISO RGD:1318576 6480464 Demecolcine results in increased expression of FOXP1 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1318576 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FOXP1 mRNA CTD PMID:22079256 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of FOXP1 mRNA CTD PMID:21955143 17beta-estradiol affects expression ISO RGD:1318576 6480464 Estradiol affects the expression of FOXP1 mRNA CTD PMID:22574217 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO RGD:1308669 6480464 2 more ... CTD PMID:23829299 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of FOXP1 mRNA CTD PMID:24058054 , PMID:26290441 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of FOXP1 mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression ISO RGD:1308669 6480464 2, 4-dinitrotoluene affects the expression of FOXP1 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression ISO RGD:1308669 6480464 2, 6-dinitrotoluene affects the expression of FOXP1 mRNA CTD PMID:21346803 2-butoxyethanol decreases expression EXP 6480464 n-butoxyethanol results in decreased expression of FOXP1 mRNA CTD PMID:19812364 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1318576 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FOXP1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXP1 mRNA CTD PMID:28628672 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of FOXP1 mRNA CTD PMID:19191707 4-vinylcyclohexene dioxide affects expression EXP 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of FOXP1 mRNA CTD PMID:20829426 acrylamide decreases expression ISO RGD:1308669 6480464 Acrylamide results in decreased expression of FOXP1 mRNA CTD PMID:28959563 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of FOXP1 mRNA CTD PMID:19770486 aflatoxin B1 increases methylation ISO RGD:1318576 6480464 Aflatoxin B1 results in increased methylation of FOXP1 gene more ... CTD PMID:27153756 , PMID:30157460 all-trans-retinoic acid increases expression ISO RGD:1318576 6480464 Tretinoin results in increased expression of FOXP1 mRNA CTD PMID:21934132 all-trans-retinoic acid increases expression ISO RGD:1308669 6480464 Tretinoin results in increased expression of FOXP1 mRNA CTD PMID:20488242 amphetamine decreases expression ISO RGD:1308669 6480464 Amphetamine results in decreased expression of FOXP1 mRNA CTD PMID:30779732 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of FOXP1 mRNA CTD PMID:23650126 arsane increases methylation ISO RGD:1318576 6480464 Arsenic results in increased methylation of FOXP1 promoter CTD PMID:21291286 arsane affects methylation ISO RGD:1318576 6480464 Arsenic affects the methylation of FOXP1 gene CTD PMID:25304211 arsenic atom increases methylation ISO RGD:1318576 6480464 Arsenic results in increased methylation of FOXP1 promoter CTD PMID:21291286 arsenic atom affects methylation ISO RGD:1318576 6480464 Arsenic affects the methylation of FOXP1 gene CTD PMID:25304211 benzo[a]pyrene decreases expression ISO RGD:1318576 6480464 Benzo(a)pyrene results in decreased expression of FOXP1 mRNA CTD PMID:20064835 benzo[a]pyrene affects methylation ISO RGD:1318576 6480464 Benzo(a)pyrene affects the methylation of FOXP1 intron CTD PMID:30157460 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of FOXP1 mRNA CTD PMID:21569818 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1318576 6480464 7 more ... CTD PMID:20382639 Benzo[k]fluoranthene decreases expression EXP 6480464 benzo(k)fluoranthene results in decreased expression of FOXP1 mRNA CTD PMID:26377693 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of FOXP1 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of FOXP1 mRNA] CTD PMID:19850644 bisphenol A decreases expression ISO RGD:1318576 6480464 bisphenol A results in decreased expression of FOXP1 mRNA CTD PMID:22576693 bisphenol A increases methylation ISO RGD:1308669 6480464 bisphenol A results in increased methylation of FOXP1 gene CTD PMID:28505145 bisphenol A multiple interactions ISO RGD:1318576 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FOXP1 mRNA CTD PMID:28628672 bisphenol A affects methylation EXP 6480464 bisphenol A affects the methylation of FOXP1 promoter CTD PMID:27334623 bisphenol A increases expression ISO RGD:1308669 6480464 bisphenol A results in increased expression of FOXP1 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO RGD:1318576 6480464 bisphenol A results in increased methylation of FOXP1 gene CTD PMID:22576693 , PMID:25663935 bisphenol F multiple interactions ISO RGD:1318576 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXP1 mRNA CTD PMID:28628672 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of FOXP1 mRNA, Nanotubes, Carbon results in decreased expression of FOXP1 mRNA CTD PMID:25554681 chromium(6+) decreases expression ISO RGD:1318576 6480464 chromium hexavalent ion results in decreased expression of FOXP1 mRNA CTD PMID:30690063 cisplatin multiple interactions ISO RGD:1318576 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of FOXP1 mRNA CTD PMID:27392435 cisplatin decreases expression ISO RGD:1318576 6480464 Cisplatin results in decreased expression of FOXP1 mRNA CTD PMID:27392435 copper(II) sulfate increases expression ISO RGD:1318576 6480464 Copper Sulfate results in increased expression of FOXP1 mRNA CTD PMID:19549813 cyclosporin A increases expression ISO RGD:1318576 6480464 Cyclosporine results in increased expression of FOXP1 mRNA CTD PMID:25562108 cyclosporin A multiple interactions ISO RGD:1308669 6480464 Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [FOXP1 protein binds to RCAN1 promoter]], FOXP1 protein promotes the reaction [Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [NFATC4 protein results in increased expression of RCAN1 mRNA]]] CTD PMID:21606195 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of FOXP1 mRNA CTD PMID:22733784 dexamethasone multiple interactions ISO RGD:1318576 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FOXP1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXP1 mRNA CTD PMID:28628672 dexamethasone decreases expression ISO RGD:1318576 6480464 Dexamethasone results in decreased expression of FOXP1 mRNA CTD PMID:25047013 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of FOXP1 mRNA CTD PMID:21266533 disodium selenite increases expression ISO RGD:1318576 6480464 Sodium Selenite results in increased expression of FOXP1 mRNA CTD PMID:18175754 diuron decreases expression ISO RGD:1308669 6480464 Diuron results in decreased expression of FOXP1 mRNA CTD PMID:21551480 dorsomorphin multiple interactions ISO RGD:1318576 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXP1 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1318576 6480464 Doxorubicin results in decreased expression of FOXP1 mRNA CTD PMID:29803840 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of FOXP1 mRNA CTD PMID:21955143 formaldehyde increases expression ISO RGD:1318576 6480464 Formaldehyde results in increased expression of FOXP1 mRNA CTD PMID:23649840 gentamycin increases expression ISO RGD:1308669 6480464 Gentamicins results in increased expression of FOXP1 mRNA CTD PMID:22061828 hydralazine multiple interactions ISO RGD:1318576 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of FOXP1 mRNA CTD PMID:17183730 indometacin multiple interactions ISO RGD:1318576 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FOXP1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of FOXP1 mRNA CTD PMID:28628672 ionomycin multiple interactions ISO RGD:1308669 6480464 Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [FOXP1 protein binds to RCAN1 promoter]] more ... CTD PMID:21606195 leflunomide increases expression ISO RGD:1318576 6480464 leflunomide results in increased expression of FOXP1 mRNA CTD PMID:28988120 menadione affects expression ISO RGD:1318576 6480464 Vitamin K 3 affects the expression of FOXP1 mRNA CTD PMID:20044591 methapyrilene decreases expression ISO RGD:1308669 6480464 Methapyrilene results in decreased expression of FOXP1 mRNA CTD PMID:30467583 methoxychlor affects expression EXP 6480464 Methoxychlor affects the expression of FOXP1 mRNA CTD PMID:20829426 methylmercury chloride increases expression ISO RGD:1318576 6480464 methylmercuric chloride results in increased expression of FOXP1 mRNA CTD PMID:28001369 morphine increases expression EXP 6480464 Morphine results in increased expression of FOXP1 mRNA CTD PMID:21955143 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of FOXP1 mRNA CTD PMID:21955143 oxaliplatin multiple interactions ISO RGD:1308669 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of FOXP1 mRNA CTD PMID:25729387 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of FOXP1 mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:1318576 6480464 Acetaminophen results in decreased expression of FOXP1 mRNA CTD PMID:21420995 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of FOXP1 mRNA CTD PMID:23091169 phenylmercury acetate increases expression ISO RGD:1318576 6480464 Phenylmercuric Acetate results in increased expression of FOXP1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1318576 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXP1 mRNA CTD PMID:27188386 pirinixic acid multiple interactions ISO RGD:1318576 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FOXP1 mRNA CTD PMID:19710929 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of FOXP1 mRNA CTD PMID:17426115 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of FOXP1 mRNA CTD PMID:19710929 potassium chromate multiple interactions ISO RGD:1318576 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FOXP1 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1318576 6480464 potassium chromate(VI) results in decreased expression of FOXP1 mRNA CTD PMID:22079256 , PMID:22714537 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of FOXP1 mRNA CTD PMID:21278054 quercetin decreases expression ISO RGD:1318576 6480464 Quercetin results in decreased expression of FOXP1 mRNA CTD PMID:21632981 rifampicin increases expression ISO RGD:1318576 6480464 Rifampin results in increased expression of FOXP1 mRNA CTD PMID:24552687 rotenone increases expression ISO RGD:1308669 6480464 Rotenone results in increased expression of FOXP1 mRNA CTD PMID:28374803 SB 431542 multiple interactions ISO RGD:1318576 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FOXP1 mRNA CTD PMID:27188386 silver atom decreases expression EXP 6480464 Silver results in decreased expression of FOXP1 mRNA CTD PMID:27131904 silver atom increases expression ISO RGD:1318576 6480464 Silver results in increased expression of FOXP1 mRNA CTD PMID:26014281 silver(0) decreases expression EXP 6480464 Silver results in decreased expression of FOXP1 mRNA CTD PMID:27131904 silver(0) increases expression ISO RGD:1318576 6480464 Silver results in increased expression of FOXP1 mRNA CTD PMID:26014281 sirolimus decreases expression ISO RGD:1318576 6480464 Sirolimus results in decreased expression of FOXP1 protein CTD PMID:25663935 sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of FOXP1 mRNA CTD PMID:30953684 Stanolone benzoate affects expression ISO RGD:1308669 6480464 stanolone benzoate affects the expression of FOXP1 mRNA, stanolone benzoate affects the expression of FOXP1 protein CTD PMID:25247470 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of FOXP1 mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of FOXP1 mRNA CTD PMID:21641980 , PMID:26378955 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of FOXP1 mRNA CTD PMID:17484886 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of FOXP1 mRNA CTD PMID:23557971 topotecan decreases expression ISO RGD:1308669 6480464 Topotecan results in decreased expression of FOXP1 mRNA CTD PMID:25729387 topotecan multiple interactions ISO RGD:1308669 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of FOXP1 mRNA CTD PMID:25729387 triclosan decreases expression ISO RGD:1318576 6480464 Triclosan results in decreased expression of FOXP1 mRNA CTD PMID:30510588 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of FOXP1 mRNA CTD PMID:28973697 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of FOXP1 mRNA CTD PMID:30912803 valproic acid multiple interactions ISO RGD:1318576 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of FOXP1 mRNA CTD PMID:17183730 valproic acid decreases expression ISO RGD:1318576 6480464 Valproic Acid results in decreased expression of FOXP1 mRNA CTD PMID:28001369 valproic acid increases expression ISO RGD:1318576 6480464 Valproic Acid results in increased expression of FOXP1 mRNA CTD PMID:24383497 , PMID:24935251 valproic acid affects expression ISO RGD:1318576 6480464 Valproic Acid affects the expression of FOXP1 mRNA CTD PMID:25979313 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of FOXP1 mRNA CTD PMID:19136453 vinclozolin decreases expression ISO RGD:1308669 6480464 vinclozolin results in decreased expression of FOXP1 mRNA CTD PMID:23034163 vincristine increases expression ISO RGD:1318576 6480464 Vincristine results in increased expression of FOXP1 mRNA CTD PMID:23649840 wortmannin decreases expression ISO RGD:1318576 6480464 wortmannin results in decreased expression of FOXP1 protein CTD PMID:25663935
Biological Process cardiac muscle cell differentiation IMP MGI:MGI:3056542 2290270 (MGI:MGI:3056209, PMID:15342473) MGI MGI:MGI:3056209 , PMID:15342473 cardiac muscle cell differentiation IMP MGI:MGI:4829787 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 cardiovascular system development IGI MGI:MGI:97350 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 cardiovascular system development IMP MGI:MGI:4829787 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 cellular response to ionomycin ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 heart development IMP MGI:MGI:3056542 2290270 (MGI:MGI:3056209, PMID:15342473) MGI MGI:MGI:3056209 , PMID:15342473 heart development IMP MGI:MGI:4829787 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 immunoglobulin V(D)J recombination IMP MGI:MGI:3711150 2290270 (MGI:MGI:3662963, PMID:16819554) MGI MGI:MGI:3662963 , PMID:16819554 in utero embryonic development IMP MGI:MGI:4829787 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 innate vocalization behavior IMP MGI:MGI:3711150 2290270 (MGI:MGI:5697988, PMID:26494785) MGI MGI:MGI:5697988 , PMID:26494785 interleukin-21 secretion IDA 2290270 (MGI:MGI:5607369, PMID:24859450) UniProtKB MGI:MGI:5607369 , PMID:24859450 lung development IGI MGI:MGI:2148705 2290270 (MGI:MGI:3710027, PMID:17428829) MGI MGI:MGI:3710027 , PMID:17428829 lung secretory cell differentiation IGI MGI:MGI:1921373 2290270 (MGI:MGI:5429471, PMID:22675208) MGI MGI:MGI:5429471 , PMID:22675208 motor neuron axon guidance IMP 2290270 (MGI:MGI:4849611, PMID:20711475) UniProtKB MGI:MGI:4849611 , PMID:20711475 negative regulation of cell growth involved in cardiac muscle cell development ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 negative regulation of lung goblet cell differentiation IGI MGI:MGI:1921373 2290270 (MGI:MGI:5429471, PMID:22675208) MGI MGI:MGI:5429471 , PMID:22675208 negative regulation of transcription by RNA polymerase II IDA 2290270 (MGI:MGI:2137760 more ... MGI MGI:MGI:2137760 more ... negative regulation of transcription by RNA polymerase II ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 negative regulation of transcription by RNA polymerase II IGI MGI:MGI:1337080 2290270 (MGI:MGI:3777491, PMID:18347093) MGI MGI:MGI:3777491 , PMID:18347093 negative regulation of transcription, DNA-templated IDA 2290270 (MGI:MGI:2137760, PMID:11358962) MGI MGI:MGI:2137760 , PMID:11358962 positive regulation of epithelial cell proliferation IGI MGI:MGI:2148705 2290270 (MGI:MGI:3710027, PMID:17428829) MGI MGI:MGI:3710027 , PMID:17428829 positive regulation of hydrogen peroxide-induced cell death ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of immunoglobulin production IMP MGI:MGI:3711150 2290270 (MGI:MGI:3662963, PMID:16819554) MGI MGI:MGI:3662963 , PMID:16819554 positive regulation of mesenchymal cell proliferation IGI MGI:MGI:2148705 2290270 (MGI:MGI:3710027, PMID:17428829) MGI MGI:MGI:3710027 , PMID:17428829 positive regulation of transcription by RNA polymerase II IMP MGI:MGI:4829787 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 positive regulation of transcription, DNA-templated IMP 2290270 (MGI:MGI:4849611, PMID:20711475) UniProtKB MGI:MGI:4849611 , PMID:20711475 pre-B cell differentiation IMP MGI:MGI:3711150 2290270 (MGI:MGI:3662963, PMID:16819554) MGI MGI:MGI:3662963 , PMID:16819554 regulation of action potential IMP MGI:MGI:3711150 2290270 (MGI:MGI:5697988, PMID:26494785) MGI MGI:MGI:5697988 , PMID:26494785 regulation of cardiac muscle cell proliferation IGI MGI:MGI:1891346 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 regulation of cardiac muscle cell proliferation IMP 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 regulation of lung goblet cell differentiation IGI MGI:MGI:1344405 , MGI:MGI:1921373 2290270 (MGI:MGI:5429471, PMID:22675208) MGI MGI:MGI:5429471 , PMID:22675208 regulation of transcription, DNA-templated IEA InterPro:IPR001766 , InterPro:IPR030456 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 sarcomere organization IGI MGI:MGI:97350 2290270 (MGI:MGI:4829405, PMID:20713518) MGI MGI:MGI:4829405 , PMID:20713518 skeletal muscle tissue development IGI MGI:MGI:2148705 2290270 (MGI:MGI:3710027, PMID:17428829) MGI MGI:MGI:3710027 , PMID:17428829 smooth muscle tissue development IGI MGI:MGI:2148705 2290270 (MGI:MGI:3710027, PMID:17428829) MGI MGI:MGI:3710027 , PMID:17428829 T follicular helper cell differentiation IDA 2290270 (MGI:MGI:5607369, PMID:24859450) UniProtKB MGI:MGI:5607369 , PMID:24859450 ventral spinal cord development IEP 2290270 (PMID:20711475) UniProtKB PMID:20711475 Cellular Component cytoplasm ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 nucleus IC GO:0000122 2290270 (MGI:MGI:3606794, PMID:14701752) MGI MGI:MGI:3606794 , PMID:14701752 nucleus IDA 2290270 (MGI:MGI:3662963 more ... MGI MGI:MGI:3662963 more ... nucleus ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 Molecular Function chromatin binding IDA 2290270 (MGI:MGI:3777491, PMID:18347093) MGI MGI:MGI:3777491 , PMID:18347093 DNA binding IDA 2290270 (MGI:MGI:3606794, PMID:14701752) MGI MGI:MGI:3606794 , PMID:14701752 DNA-binding transcription factor activity IDA 2290270 (MGI:MGI:3710027 more ... MGI MGI:MGI:3710027 more ... DNA-binding transcription factor activity TAS 2290270 (MGI:MGI:5697988, PMID:26494785) MGI MGI:MGI:5697988 , PMID:26494785 DNA-binding transcription factor activity, RNA polymerase II-specific IDA 2290270 (MGI:MGI:3662963, PMID:16819554) MGI MGI:MGI:3662963 , PMID:16819554 DNA-binding transcription factor activity, RNA polymerase II-specific IGI MGI:MGI:1337080 2290270 (MGI:MGI:3777491, PMID:18347093) MGI MGI:MGI:3777491 , PMID:18347093 metal ion binding IEA UniProtKB-KW:KW-0479 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 protein binding IPI UniProtKB:O88712 2290270 (MGI:MGI:3606794, PMID:14701752) UniProtKB MGI:MGI:3606794 , PMID:14701752 protein heterodimerization activity IPI UniProtKB:P58463 , UniProtKB:Q9DBY0 2290270 (MGI:MGI:3606794, PMID:14701752) MGI MGI:MGI:3606794 , PMID:14701752 protein homodimerization activity IPI UniProtKB:P58462 2290270 (MGI:MGI:3606794, PMID:14701752) MGI MGI:MGI:3606794 , PMID:14701752 RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP 2290270 (MGI:MGI:3606794, PMID:14701752) NTNU_SB MGI:MGI:3606794 , PMID:14701752 sequence-specific DNA binding IEA InterPro:IPR001766 , InterPro:IPR030456 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 transcription factor binding ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 transcription regulatory region DNA binding ISO RGD:1308669 2290270 RGD GO_REF:0000096, MGI:MGI:4417868
Gene-Chemical Interaction Annotations
