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Gene: Clk2 (CDC-like kinase 2) Mus musculus
Symbol: Clk2
Name: CDC-like kinase 2
Description: Exhibits protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in negative regulation of gluconeogenesis; protein phosphorylation; and response to retinoic acid. Localizes to the nucleus. Is expressed in several structures, including brain; genitourinary system; liver; retina; and thyroid gland. Orthologous to human CLK2 (CDC like kinase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU041688; Clk2-Scamp3 protein; dual specificity protein kinase CLK2; Tu52
Homo sapiens (human) : CLK2 (CDC like kinase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Clk2 (CDC-like kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clk2 (CDC like kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLK2 (CDC like kinase 2)
Canis lupus familiaris (dog) : CLK2 (CDC like kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clk2 (CDC like kinase 2)
Sus scrofa (pig) : CLK2 (CDC like kinase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38389,164,795 - 89,177,087 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37388,968,727 - 88,981,009 (+)NCBIGRCm37mm9NCBIm37
MGSCv36389,251,010 - 89,262,516 (+)NCBImm8
Celera389,198,450 - 89,210,762 (+)NCBICelera
Cytogenetic Map3 F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Clk2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553389
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.