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Gene: Fkbp1b (FK506 binding protein 1b) Mus musculus
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Symbol: Fkbp1b
Name: FK506 binding protein 1b
RGD ID: 62126
Description: Exhibits FK506 binding activity; ion channel binding activity; and peptidyl-prolyl cis-trans isomerase activity. Involved in several processes, including negative regulation of insulin secretion involved in cellular response to glucose stimulus; neuronal action potential propagation; and regulation of sequestering of calcium ion. Localizes to calcium channel complex and sarcoplasmic reticulum membrane. Used to study catecholaminergic polymorphic ventricular tachycardia. Human ortholog(s) of this gene implicated in Graves' disease. Orthologous to human FKBP1B (FKBP prolyl isomerase 1B); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; 12.6kD; 12.6kDa; AW494148; cals; calstabin2; FK506-binding protein 12.6; FK506-binding protein 1B; FKBP-12.6; FKBP-1B; FKBP12.; FKBP12.6; immunophilin FKBP12.6; peptidyl-prolyl cis-trans isomerase FKBP1B; PPIase FKBP1B; rotamase
Orthologs:
Homo sapiens (human) : FKBP1B (FKBP prolyl isomerase 1B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fkbp1b (FKBP prolyl isomerase 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp1b (FKBP prolyl isomerase 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP1B (FKBP prolyl isomerase 1B)
Canis lupus familiaris (dog) : FKBP1B (FKBP prolyl isomerase 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp1b (FKBP prolyl isomerase 1B)
Sus scrofa (pig) : FKBP1B (FKBP prolyl isomerase 1B)
Chlorocebus sabaeus (African green monkey) : FKBP1B (FKBP prolyl isomerase 1B)
Heterocephalus glaber (naked mole-rat) : Fkbp1b (FKBP prolyl isomerase 1B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39124,883,174 - 4,891,736 (-)NCBI
GRCm38124,833,176 - 4,841,573 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl124,833,174 - 4,841,591 (-)EnsemblGRCm38mm10GRCm38
MGSCv37124,839,980 - 4,848,401 (-)NCBIGRCm37mm9NCBIm37
MGSCv36124,855,524 - 4,863,925 (-)NCBImm8
Celera124,764,579 - 4,773,000 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fkbp1b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62126
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.