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Gene: Pde4d (phosphodiesterase 4D, cAMP specific) Mus musculus
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Symbol: Pde4d
Name: phosphodiesterase 4D, cAMP specific
Description: Exhibits 3',5'-cyclic-AMP phosphodiesterase activity; ATPase binding activity; and ion channel binding activity. Involved in several processes, including cellular response to epinephrine stimulus; regulation of heart contraction; and regulation of release of sequestered calcium ion into cytosol. Localizes to centrosome and voltage-gated calcium channel complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in acrodysostosis. Orthologous to human PDE4D (phosphodiesterase 4D); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9630011N22Rik; AI452195; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific phosphodiesterase 4D; cyclic AMP specific phosphodiesterase PDE4D5A; Dpde3; dunce; expressed sequence AI452195
Orthologs:
Homo sapiens (human) : PDE4D (phosphodiesterase 4D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pde4d (phosphodiesterase 4D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pde4d (phosphodiesterase 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : PDE4D (phosphodiesterase 4D)
Canis lupus familiaris (dog) : PDE4D (phosphodiesterase 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pde4d (phosphodiesterase 4D)
Sus scrofa (pig) : PDE4D (phosphodiesterase 4D)
Chlorocebus sabaeus (African green monkey) : PDE4D (phosphodiesterase 4D)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl13108,449,948 - 109,953,461 (+)EnsemblGRCm38mm10GRCm38
GRCm3813108,654,177 - 109,955,969 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3713109,444,371 - 110,741,682 (+)NCBIGRCm37mm9NCBIm37
MGSCv3613109,775,041 - 111,072,352 (+)NCBImm8
Celera13112,976,414 - 114,285,878 (+)NCBICelera
Cytogenetic Map13D2.1NCBI
cM Map1359.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on Pde4d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11066
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.