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Gene: Agap2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) Mus musculus
Symbol: Agap2
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
RGD ID: 1619007
Description: Predicted to have several functions, including GTPase activity; enzyme regulator activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including mammary gland alveolus development; positive regulation of mammary gland epithelial cell proliferation; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to localize to several cellular components, including Flemming body; endosome; and nucleoplasm. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human AGAP2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGAP-2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; centaurin, gamma 1; centaurin-gamma-1; Centg; Centg1; cnt-g1; mKIAA0167; phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; PIKE
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl10127,075,284 - 127,093,169 (+)EnsemblGRCm38mm10GRCm38
GRCm3810127,075,269 - 127,093,170 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,515,963 - 126,530,225 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610126,481,856 - 126,496,118 (+)NCBImm8
Celera10129,471,732 - 129,485,790 (+)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Agap2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1619007
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.