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ONTOLOGY REPORT - ANNOTATIONS


Term:triacsin C
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Accession:CHEBI:144441 term browser browse the term
Definition:A nitroso compound that is N-undecylnitrous hydrazide carrying double bonds at positions 1,2,4, and 7. It is a long-chain fatty acyl CoA synthetase inhibitor and interferes with lipid metabolism by inhibiting the de novo synthesis of glycerolipids and cholesterol esters.
Synonyms:exact_synonym: N-[(1E,2E,4E,7E)-undeca-2,4,7-trien-1-ylidene]nitrous hydrazide
 related_synonym: (2E,4E,7E)-2,4,7-undecatrienal nitrosohydrazone;   2,4,7-undecatrienal nitrosohydrazone;   FR 900190;   Formula=C11H17N3O;   InChI=1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+;   InChIKey=NKTGCVUIESDXPU-YLEPRARLSA-N;   SMILES=C(/C=C/C=C/C/C=C/CCC)=N\\NN=O;   WS 1228A;   nitrosohydrazone-2E,4E,7E-undecatrienal
 xref: CAS:76896-80-5 "ChemIDplus";   LINCS:LSM-43284
 xref_mesh: MESH:C034613
 xref: MetaCyc:CPD-14770;   PMID:15249192 "Europe PMC";   PMID:17446697 "Europe PMC";   PMID:18653998 "Europe PMC";   PMID:1999415 "Europe PMC";   PMID:23565210 "Europe PMC";   PMID:26719343 "Europe PMC";   PMID:28918598 "Europe PMC";   PMID:3117118 "Europe PMC";   PMID:6804425 "Europe PMC";   PMID:6804426 "Europe PMC";   PMID:9182714 "Europe PMC";   Wikipedia:Triacsin_C


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triacsin C term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Abcd3 ATP binding cassette subfamily D member 3 JBrowse link 2 225,335,708 225,389,120 RGD:6480464
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:6480464
G Adarb1 adenosine deaminase, RNA-specific, B1 JBrowse link 20 11,972,352 12,101,022 RGD:6480464
G Aqp3 aquaporin 3 (Gill blood group) JBrowse link 5 57,423,735 57,429,252 RGD:6480464
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Col18a1 collagen type XVIII alpha 1 chain JBrowse link 20 12,225,202 12,332,858 RGD:6480464
G Ctdspl CTD small phosphatase like JBrowse link 8 127,065,292 127,726,248 RGD:6480464
G Ddit4 DNA-damage-inducible transcript 4 JBrowse link 20 29,509,283 29,511,382 RGD:6480464
G Ddx24 DEAD-box helicase 24 JBrowse link 6 127,302,201 127,319,382 RGD:6480464
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:6480464
G Ebp EBP, cholestenol delta-isomerase JBrowse link X 15,049,394 15,055,782 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Erg28 ergosterol biosynthesis 28 homolog JBrowse link 6 109,683,252 109,692,218 RGD:6480464
G Fgfr3 fibroblast growth factor receptor 3 JBrowse link 14 82,272,322 82,287,739 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gnpda1 glucosamine-6-phosphate deaminase 1 JBrowse link 18 31,479,117 31,489,154 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 JBrowse link 2 250,467,428 250,600,517 RGD:6480464
G Hspb11 heat shock protein family B (small), member 11 JBrowse link 5 126,856,128 126,882,913 RGD:6480464
G Id3 inhibitor of DNA binding 3, HLH protein JBrowse link 5 154,489,603 154,491,172 RGD:6480464
G Idi1 isopentenyl-diphosphate delta isomerase 1 JBrowse link 17 57,976,266 57,984,036 RGD:6480464
G Igfbp7 insulin-like growth factor binding protein 7 JBrowse link 14 33,010,300 33,070,193 RGD:6480464
G Ilvbl ilvB acetolactate synthase like JBrowse link 7 14,044,586 14,054,639 RGD:6480464
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:6480464
G Itga6 integrin subunit alpha 6 JBrowse link 3 58,442,904 58,515,124 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:6480464
G Lss lanosterol synthase JBrowse link 20 12,844,522 12,870,474 RGD:6480464
G Luc7l3 LUC7-like 3 pre-mRNA splicing factor JBrowse link 10 81,991,147 82,027,119 RGD:6480464
G Maff MAF bZIP transcription factor F JBrowse link 7 120,580,743 120,592,095 RGD:6480464
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 JBrowse link 2 5,569,954 5,579,894 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 3 43,111,258 43,128,391 RGD:6480464
G Nrtn neurturin JBrowse link 9 10,299,881 10,306,599 RGD:6480464
G Pde4dip phosphodiesterase 4D interacting protein JBrowse link 2 199,867,965 200,066,034 RGD:6480464
G Pdss2 decaprenyl diphosphate synthase subunit 2 JBrowse link 20 47,966,513 48,192,747 RGD:6480464
G Phlda1 pleckstrin homology-like domain, family A, member 1 JBrowse link 7 54,247,460 54,249,664 RGD:6480464
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:6480464
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 2 54,857,688 54,893,404 RGD:6480464
G Prpf4 pre-mRNA processing factor 4 JBrowse link 5 78,267,248 78,281,172 RGD:6480464
G Psat1 phosphoserine aminotransferase 1 JBrowse link 1 233,124,089 233,145,941 RGD:6480464
G Ptp4a1 protein tyrosine phosphatase 4A1 JBrowse link 9 37,223,363 37,254,222 RGD:6480464
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:6480464
G Skp2 S-phase kinase associated protein 2 JBrowse link 2 58,506,146 58,534,211 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:6480464
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:6480464
G Sparc secreted protein acidic and cysteine rich JBrowse link 10 40,742,390 40,764,232 RGD:6480464
G Spast spastin JBrowse link 6 22,230,067 22,282,166 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 JBrowse link 13 48,065,280 48,286,888 RGD:6480464
G Stc2 stanniocalcin 2 JBrowse link 10 16,542,909 16,552,675 RGD:6480464
G Tnfrsf12a TNF receptor superfamily member 12A JBrowse link 10 12,995,904 12,997,930 RGD:6480464
G Tns3 tensin 3 JBrowse link 14 88,673,922 88,907,874 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Ucp3 uncoupling protein 3 JBrowse link 1 165,482,912 165,495,895 RGD:6480464
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        inhibitor 18059
          apoptosis inhibitor 6554
            triacsin C 64
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon group molecular entity 19428
                          organic molecular entity 19420
                            heteroorganic entity 19003
                              organonitrogen compound 18076
                                hydrazone 524
                                  triacsin C 64
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.