Mir22 (microRNA 22) - Rat Genome Database

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Gene: Mir22 (microRNA 22) Mus musculus
Analyze
Symbol: Mir22
Name: microRNA 22
RGD ID: 1608348
MGI Page MGI
Description: Acts upstream of or within several processes, including cellular response to phenylalanine; long-term synaptic potentiation; and sensory perception of sound. Is expressed in cerebellum and telencephalon. Orthologous to human MIR22 (microRNA 22).
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: Mir; Mirn22; mmu-mir-; mmu-mir-22
RGD Orthologs
Human
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,354,542 - 75,354,636 (+)NCBIGRCm39mm39
GRCm39 Ensembl1175,354,542 - 75,354,636 (+)Ensembl
GRCm381175,463,716 - 75,463,810 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,463,716 - 75,463,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv371175,277,218 - 75,277,312 (+)NCBIGRCm37mm9NCBIm37
Celera1182,972,112 - 82,972,206 (+)NCBICelera
Cytogenetic Map11B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12007417   PMID:12554860   PMID:12919684   PMID:15538371   PMID:16381832   PMID:17369397   PMID:17604727   PMID:20215419   PMID:20413612   PMID:20548288   PMID:20582318   PMID:20589883  
PMID:21267068   PMID:21718763   PMID:22538858   PMID:22570371   PMID:23251709   PMID:23355742   PMID:23524588   PMID:23646144   PMID:23671190   PMID:23827711   PMID:24086656   PMID:24163368  
PMID:24558412   PMID:24631284   PMID:24794437   PMID:25375881   PMID:25722434   PMID:25751060   PMID:25826372   PMID:25858512   PMID:25926441   PMID:26107383   PMID:26112332   PMID:26193896  
PMID:26437241   PMID:26631939   PMID:26822703   PMID:27481129   PMID:27569277   PMID:27614440   PMID:27997889   PMID:28112401   PMID:28294194   PMID:28314781   PMID:28739418   PMID:28911907  
PMID:29059152   PMID:29101298   PMID:29246895   PMID:29288528   PMID:29336471   PMID:29588073   PMID:29709471   PMID:29791781   PMID:31677784   PMID:31840653   PMID:31891366   PMID:31964468  
PMID:32056303   PMID:32518131   PMID:32522250   PMID:32708470   PMID:32825833   PMID:33000497   PMID:33004906   PMID:33097254   PMID:33252886   PMID:33549579   PMID:33650318   PMID:33664851  
PMID:34059381   PMID:34081624   PMID:34345013  


Genomics

Comparative Map Data
Mir22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,354,542 - 75,354,636 (+)NCBIGRCm39mm39
GRCm39 Ensembl1175,354,542 - 75,354,636 (+)Ensembl
GRCm381175,463,716 - 75,463,810 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1175,463,716 - 75,463,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv371175,277,218 - 75,277,312 (+)NCBIGRCm37mm9NCBIm37
Celera1182,972,112 - 82,972,206 (+)NCBICelera
Cytogenetic Map11B5NCBI
MIR22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl171,713,903 - 1,713,987 (-)EnsemblGRCh38hg38GRCh38
GRCh38171,713,903 - 1,713,987 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37171,617,197 - 1,617,281 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,563,946 - 1,564,030 (-)NCBINCBI36hg18NCBI36
Celera171,632,905 - 1,632,989 (-)NCBI
Cytogenetic Map17p13.3NCBI
HuRef171,516,889 - 1,516,973 (-)NCBIHuRef
CHM1_1171,626,968 - 1,627,052 (-)NCBICHM1_1
Mir22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21060,307,039 - 60,307,133 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1060,307,039 - 60,307,133 (+)Ensembl
Rnor_6.01062,299,592 - 62,299,686 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,299,592 - 62,299,686 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01062,013,642 - 62,013,736 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1059,335,476 - 59,335,570 (+)NCBICelera
Cytogenetic Map10q24NCBI
MIR22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,852,534 - 45,852,593 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,852,517 - 45,852,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,003,215 - 45,003,274 (-)NCBI
ROS_Cfam_1.0946,679,619 - 46,679,678 (-)NCBI
UMICH_Zoey_3.1945,449,590 - 45,449,649 (-)NCBI
UNSW_CanFamBas_1.0945,743,952 - 45,744,011 (-)NCBI
UU_Cfam_GSD_1.0945,798,566 - 45,798,625 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Ass1mmu-miR-22-3pMirtarbaseexternal_infoMicroarray//qRT-PCR//Quantitative proteomic approaFunctional MTI (Weak)19878148
Arpc5mmu-miR-22-3pMirtarbaseexternal_infoImmunohistochemistry//Luciferase reporter assay//qFunctional MTI22447776
Ywhazmmu-miR-22-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23355742
Irf8mmu-miR-22-3pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)23251709
Erbb3mmu-miR-22-3pOncomiRDBexternal_infoNANA22484852
Hif1ammu-miR-22-3pOncomiRDBexternal_infoNANA21629773
Cdkn1ammu-miR-22-3pOncomiRDBexternal_infoNANA21565979
Dand5mmu-miR-22-3pOncomiRDBexternal_infoNANA21502362
Hdac5mmu-miR-22-3pOncomiRDBexternal_infoNANA20842113
Mycbpmmu-miR-22-3pOncomiRDBexternal_infoNANA20562918
Maxmmu-miR-22-3pOncomiRDBexternal_infoNANA20214878
Esr1mmu-miR-22-3pOncomiRDBexternal_infoNANA20180843
Esr1mmu-miR-22-3pOncomiRDBexternal_infoNANA19414598

Predicted Targets
Summary Value
Count of predictions:30980
Count of gene targets:12493
Count of transcripts:22428
Interacting mature miRNAs:mmu-miR-22-3p, mmu-miR-22-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000083595
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1175,354,542 - 75,354,636 (+)Ensembl
GRCm38.p6 Ensembl1175,463,716 - 75,463,810 (+)Ensembl
RefSeq Acc Id: NR_029739
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391175,354,542 - 75,354,636 (+)NCBI
GRCm381175,463,716 - 75,463,810 (+)ENTREZGENE
MGSCv371175,277,218 - 75,277,312 (+)RGD
Celera1182,972,112 - 82,972,206 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Promoters
RGD ID:8675542
Promoter ID:EPDNEW_M15802
Type:multiple initiation site
Name:Mir22_1
Description:Mus musculus microRNA 22 , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381175,463,796 - 75,463,856EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676896 AgrOrtholog
Ensembl Genes ENSMUSG00000065529 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083595 ENTREZGENE
MGD MGI:2676896 ENTREZGENE
miRBase MI0000570 ENTREZGENE
NCBI Gene 387141 ENTREZGENE
PhenoGen Mir22 PhenoGen
RNAcentral URS0000096022 RNACentral
  URS0000142DC3 RNACentral
  URS000075DE23 RNACentral