Eva1a (eva-1 homolog A (C. elegans)) - Rat Genome Database
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Gene: Eva1a (eva-1 homolog A (C. elegans)) Mus musculus
Analyze
Symbol: Eva1a
Name: eva-1 homolog A (C. elegans)
RGD ID: 1618148
MGI Page MGI
Description: Is expressed in foot; hand; left lung; renal calyx; and right lung. Orthologous to human EVA1A (eva-1 homolog A, regulator of programmed cell death); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC014699; Fam17; Fam176a; family with sequence similarity 176, member A; MGC25911; MGC37042; protein eva-1 homolog A; Tmem166; transmembrane protein 166
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,018,029 - 82,070,080 (+)NCBIGRCm39mm39
GRCm39 Ensembl682,018,024 - 82,070,080 (+)Ensembl
GRCm38682,041,048 - 82,093,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,041,043 - 82,093,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv37681,991,622 - 82,043,093 (+)NCBIGRCm37mm9NCBIm37
MGSCv36682,007,331 - 82,058,756 (+)NCBImm8
Celera684,034,678 - 84,086,332 (+)NCBICelera
Cytogenetic Map6C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:22967998   PMID:26905199   PMID:28044434   PMID:28151473  


Genomics

Comparative Map Data
Eva1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39682,018,029 - 82,070,080 (+)NCBIGRCm39mm39
GRCm39 Ensembl682,018,024 - 82,070,080 (+)Ensembl
GRCm38682,041,048 - 82,093,099 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl682,041,043 - 82,093,099 (+)EnsemblGRCm38mm10GRCm38
MGSCv37681,991,622 - 82,043,093 (+)NCBIGRCm37mm9NCBIm37
MGSCv36682,007,331 - 82,058,756 (+)NCBImm8
Celera684,034,678 - 84,086,332 (+)NCBICelera
Cytogenetic Map6C3NCBI
EVA1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl275,469,302 - 75,569,722 (-)EnsemblGRCh38hg38GRCh38
GRCh38275,492,318 - 75,569,719 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37275,719,444 - 75,796,845 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36275,572,952 - 75,650,356 (-)NCBINCBI36hg18NCBI36
Celera275,550,740 - 75,628,141 (-)NCBI
Cytogenetic Map2p12NCBI
HuRef275,457,364 - 75,534,681 (-)NCBIHuRef
CHM1_1275,648,737 - 75,726,128 (-)NCBICHM1_1
Eva1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24114,593,773 - 114,643,011 (+)NCBI
Rnor_6.0 Ensembl4112,773,938 - 112,823,659 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04112,714,023 - 112,823,659 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04177,461,600 - 177,511,382 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44116,280,880 - 116,330,122 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4103,592,203 - 103,641,231 (+)NCBICelera
Cytogenetic Map4q34NCBI
Eva1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542410,340,214 - 10,357,557 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542410,308,586 - 10,358,477 (+)NCBIChiLan1.0ChiLan1.0
EVA1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A77,068,221 - 77,206,594 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A77,068,221 - 77,136,854 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A75,564,684 - 75,718,677 (-)NCBIMhudiblu_PPA_v0panPan3
EVA1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1747,769,875 - 47,817,560 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11747,769,808 - 47,818,449 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Eva1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365561,659,203 - 1,728,245 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVA1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl367,680,735 - 67,734,222 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1367,710,915 - 67,730,554 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EVA1A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11431,693,196 - 31,761,317 (+)NCBI
ChlSab1.1 Ensembl1431,732,129 - 31,761,329 (+)Ensembl
Eva1a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474927,798,705 - 27,854,588 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1180
Count of miRNA genes:587
Interacting mature miRNAs:714
Transcripts:ENSMUST00000042974, ENSMUST00000149023, ENSMUST00000150691, ENSMUST00000150976
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000042974   ⟹   ENSMUSP00000037422
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl682,041,623 - 82,093,099 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149023   ⟹   ENSMUSP00000117345
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl682,052,307 - 82,092,160 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150691
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl682,041,688 - 82,047,150 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150976   ⟹   ENSMUSP00000122674
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl682,041,043 - 82,091,895 (+)Ensembl
RefSeq Acc Id: NM_145570   ⟹   NP_663545
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,018,609 - 82,070,080 (+)NCBI
GRCm38682,041,628 - 82,093,099 (+)NCBI
MGSCv37681,991,622 - 82,043,093 (+)RGD
Celera684,034,678 - 84,086,332 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505962   ⟹   XP_006506025
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,018,029 - 82,070,079 (+)NCBI
GRCm38682,041,048 - 82,093,098 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255336   ⟹   XP_030111196
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,047,722 - 82,070,079 (+)NCBI
GRCm38682,070,741 - 82,093,098 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255337   ⟹   XP_030111197
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39682,018,619 - 82,070,079 (+)NCBI
GRCm38682,041,614 - 82,093,098 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_663545   ⟸   NM_145570
- UniProtKB: Q91WM6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006506025   ⟸   XM_006505962
- Peptide Label: isoform X1
- UniProtKB: Q91WM6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030111197   ⟸   XM_030255337
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030111196   ⟸   XM_030255336
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000122674   ⟸   ENSMUST00000150976
RefSeq Acc Id: ENSMUSP00000037422   ⟸   ENSMUST00000042974
RefSeq Acc Id: ENSMUSP00000117345   ⟸   ENSMUST00000149023
Protein Domains
FAM176

Promoters
RGD ID:6839283
Promoter ID:MM_KWN:46547
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Liver,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000066736,   OTTMUST00000066737,   OTTMUST00000066738
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36681,991,351 - 81,991,851 (+)MPROMDB
RGD ID:6839284
Promoter ID:MM_KWN:46548
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000066739
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36682,002,136 - 82,002,636 (+)MPROMDB
RGD ID:6890086
Promoter ID:EPDNEW_M8494
Type:initiation region
Name:Eva1a_1
Description:Mus musculus eva-1 homolog A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8495  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38682,041,678 - 82,041,738EPDNEW
RGD ID:6890088
Promoter ID:EPDNEW_M8495
Type:single initiation site
Name:Eva1a_2
Description:Mus musculus eva-1 homolog A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8494  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38682,042,911 - 82,042,971EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2385247 AgrOrtholog
Ensembl Genes ENSMUSG00000035104 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000037422 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117345 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000122674 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000042974 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000149023 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000150976 UniProtKB/TrEMBL
InterPro EVA1_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EVA1A/B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:232146 UniProtKB/Swiss-Prot
MGD MGI:2385247 ENTREZGENE
NCBI Gene 232146 ENTREZGENE
PANTHER PTHR46780:SF14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAM176 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eva1a PhenoGen
UniProt D3Z4B6_MOUSE UniProtKB/TrEMBL
  D3Z511_MOUSE UniProtKB/TrEMBL
  EVA1A_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary G3X936 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-27 Eva1a  eva-1 homolog A (C. elegans)  Fam176a  family with sequence similarity 176, member A  Symbol and/or name change 5135510 APPROVED