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Gene: Hey1 (hairy/enhancer-of-split related with YRPW motif 1) Mus musculus
Symbol: Hey1
Name: hairy/enhancer-of-split related with YRPW motif 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; protein dimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including circulatory system development; generation of neurons; and nephron development. Localizes to the cytoplasm and nucleus. Is expressed in several structures, including branchial arch; cardiovascular system; craniocervical region; genitourinary system; and tooth. Orthologous to human HEY1 (hes related family bHLH transcription factor with YRPW motif 1); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI316788; AI414254; bHLHb31; CHF2; hairy and enhancer of split-related protein 1; hairy-related transcription factor 1; Hairy/E(spl)-related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; Herp2; hesr-1; Hesr1; HRT-1; HRT1; mHRT1
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3838,663,359 - 8,667,038 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3738,663,359 - 8,667,038 (-)NCBIGRCm37mm9NCBIm37
MGSCv3638,646,432 - 8,650,059 (-)NCBImm8
Celera38,666,683 - 8,670,362 (-)NCBICelera
Cytogenetic Map3 A1NCBI
cM Map32.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hey1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735763
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.