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Gene: Hey1 (hairy/enhancer-of-split related with YRPW motif 1) Mus musculus
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Symbol: Hey1
Name: hairy/enhancer-of-split related with YRPW motif 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; protein dimerization activity; and sequence-specific DNA binding activity. Involved in several processes, including circulatory system development; generation of neurons; and nephron development. Localizes to the cytoplasm and nucleus. Is expressed in several structures, including branchial arch; cardiovascular system; craniocervical region; genitourinary system; and tooth. Orthologous to human HEY1 (hes related family bHLH transcription factor with YRPW motif 1); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI316788; AI414254; bHLHb31; CHF2; hairy and enhancer of split-related protein 1; hairy-related transcription factor 1; Hairy/E(spl)-related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1; Herp2; hesr-1; Hesr1; HRT-1; HRT1; mHRT1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3838,663,359 - 8,667,038 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3738,663,359 - 8,667,038 (-)NCBIGRCm37mm9NCBIm37
MGSCv3638,646,432 - 8,650,059 (-)NCBImm8
Celera38,666,683 - 8,670,362 (-)NCBICelera
Cytogenetic Map3 A1NCBI
cM Map32.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hey1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735763
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.