CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: hydramethylnon
Accession: CHEBI:2630
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Definition: A member of the class of hydrazones that is used as an insecticide for control of ants and cockroaches.
Synonyms: exact_synonym: 5,5-dimethyltetrahydropyrimidin-2(1H)-one (3-[4-(trifluoromethyl)phenyl]-1-{2-[4-(trifluoromethyl)phenyl]ethenyl}prop-2-en-1-ylidene)hydrazone
related_synonym: Formula=C25H24F6N4; InChI=1S/C25H24F6N4/c1-23(2)15-32-22(33-16-23)35-34-21(13-7-17-3-9-19(10-4-17)24(26,27)28)14-8-18-5-11-20(12-6-18)25(29,30)31/h3-14H,15-16H2,1-2H3,(H2,32,33,35); InChIKey=IQVNEKKDSLOHHK-UHFFFAOYSA-N; Maxforce; SMILES=[H]C(=C([H])C(=NN=C1NCC(C)(C)CN1)C([H])=C([H])c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(F)(F)F; tetrahydro-5,5-dimethyl-2(1H)-pyrimidinone (1,5-bis(alpha,alpha,alpha-trifluoro-p-tolyl)-1,4-pentadien-3-one)hydrazone; tetrahydro-5,5-dimethyl-2(1H)-pyrimidinone (3-(4-(trifluoromethyl)phenyl)-1-(2-(4-(trifluoromethyl)phenyl)ethenyl)-2-propenylidene)hydrazone
xref: Beilstein:6015162; CAS:67485-29-4; KEGG:C10994
xref_mesh: MESH:C041642
xref: PMID:1517507; PMID:21383534; PMID:23148883; PMID:23156173; PMID:24665704; PPDB:386; Reaxys:6015162
G
Abcb1a
ATP binding cassette subfamily B member 1A
affects binding multiple interactions
ISO
hydramethylnon binds to ABCB1 protein hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]
CTD
PMID:8917702
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Dio2
iodothyronine deiodinase 2
decreases activity
ISO
hydramethylnon results in decreased activity of DIO2 protein
CTD
PMID:30561685
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
G
Abcb1a
ATP binding cassette subfamily B member 1A
affects binding multiple interactions
ISO
hydramethylnon binds to ABCB1 protein hydramethylnon inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]
CTD
PMID:8917702
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Dio2
iodothyronine deiodinase 2
decreases activity
ISO
hydramethylnon results in decreased activity of DIO2 protein
CTD
PMID:30561685
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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