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ONTOLOGY REPORT - ANNOTATIONS
Term:sevoflurane
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Accession:CHEBI:9130 term browser browse the term
Definition:An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Synonyms:related_synonym: 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane;   Formula=C4H3F7O;   InChI=1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2;   InChIKey=DFEYYRMXOJXZRJ-UHFFFAOYSA-N;   SMILES=FCOC(C(F)(F)F)C(F)(F)F;   Sevofluran;   Sevoflurano;   Sevofluranum
 xref: Beilstein:2041023;   CAS:28523-86-6;   DrugBank:DB01236;   Drug_Central:2439;   KEGG:C07520;   KEGG:D00547
 xref_mesh: MESH:C009250
 xref: Patent:DE1954268;   Patent:US3689571;   Wikipedia:Sevoflurane

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sevoflurane term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aass aminoadipate-semialdehyde synthase JBrowse link 4 50,152,005 50,208,935 RGD:6480464
G Aatf apoptosis antagonizing transcription factor JBrowse link 10 71,744,648 71,837,851 RGD:6480464
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Aco2 aconitase 2 JBrowse link 7 123,102,493 123,145,608 RGD:6480464
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 JBrowse link 11 25,342,119 25,350,938 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Alas1 5'-aminolevulinate synthase 1 JBrowse link 8 114,927,704 114,941,038 RGD:6480464
G Amd1 adenosylmethionine decarboxylase 1 JBrowse link 20 45,384,000 45,399,694 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Aqp3 aquaporin 3 (Gill blood group) JBrowse link 5 57,423,735 57,429,252 RGD:6480464
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:6480464
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 1 178,039,002 178,137,469 RGD:6480464
G Asl argininosuccinate lyase JBrowse link 12 30,160,922 30,178,348 RGD:6480464
G Atf2 activating transcription factor 2 JBrowse link 3 60,721,137 60,795,951 RGD:6480464
G Avpr1a arginine vasopressin receptor 1A JBrowse link 7 67,341,366 67,345,290 RGD:6480464
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:6480464
G Bace1 beta-secretase 1 JBrowse link 8 50,140,092 50,162,388 RGD:6480464
G Bhlhe41 basic helix-loop-helix family, member e41 JBrowse link 4 180,230,742 180,235,138 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cdh17 cadherin 17 JBrowse link 5 25,354,187 25,443,675 RGD:6480464
G Cebpb CCAAT/enhancer binding protein beta JBrowse link 3 164,424,502 164,425,933 RGD:6480464
G Ces2c carboxylesterase 2C JBrowse link 1 282,640,752 282,648,319 RGD:6480464
G Cgrrf1 cell growth regulator with ring finger domain 1 JBrowse link 15 23,619,176 23,639,622 RGD:6480464
G Chka choline kinase alpha JBrowse link 1 219,076,618 219,126,221 RGD:6480464
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 JBrowse link 1 170,238,959 170,246,858 RGD:6480464
G Cntn2 contactin 2 JBrowse link 13 49,280,913 49,314,061 RGD:6480464
G Cpt1a carnitine palmitoyltransferase 1A JBrowse link 1 218,568,157 218,629,679 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Crem cAMP responsive element modulator JBrowse link 17 57,021,704 57,090,888 RGD:6480464
G Cry2 cryptochrome circadian regulator 2 JBrowse link 3 81,314,151 81,344,143 RGD:6480464
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:6480464
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 JBrowse link 1 83,511,167 83,522,965 RGD:6480464
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 JBrowse link 1 83,103,925 83,119,578 RGD:6480464
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 JBrowse link 1 83,389,783 83,418,613 RGD:6480464
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 JBrowse link 1 83,933,974 83,947,804 RGD:6480464
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 JBrowse link 12 18,679,809 18,709,397 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Dbp D-box binding PAR bZIP transcription factor JBrowse link 1 101,687,896 101,692,845 RGD:6480464
G Dhx30 DExH-box helicase 30 JBrowse link 8 118,160,315 118,194,674 RGD:6480464
G Dnase2b deoxyribonuclease 2 beta JBrowse link 2 252,436,363 252,475,506 RGD:6480464
G Dnm1l dynamin 1-like JBrowse link 11 88,830,968 88,882,271 RGD:6480464
G Dusp16 dual specificity phosphatase 16 JBrowse link 4 168,470,141 168,551,346 RGD:6480464
G Dusp6 dual specificity phosphatase 6 JBrowse link 7 41,475,163 41,479,393 RGD:6480464
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Efna1 ephrin A1 JBrowse link 2 188,588,808 188,596,156 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Egr2 early growth response 2 JBrowse link 20 22,452,170 22,461,018 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Fads2 fatty acid desaturase 2 JBrowse link 1 225,906,582 226,152,568 RGD:6480464
G Fmo2 flavin containing dimethylaniline monoxygenase 2 JBrowse link 13 80,752,526 80,775,264 RGD:6480464
G Foxa3 forkhead box A3 JBrowse link 1 79,921,292 79,930,219 RGD:6480464
G Fst follistatin JBrowse link 2 46,537,589 46,544,813 RGD:6480464
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 JBrowse link 20 1,955,344 1,984,907 RGD:6480464
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 JBrowse link 14 39,662,411 39,801,082 RGD:6480464
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 JBrowse link 14 38,631,192 39,112,598 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 JBrowse link 10 27,090,913 27,179,786 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:6480464
G Gck glucokinase JBrowse link 14 86,149,146 86,191,589 RGD:6480464
G Gja4 gap junction protein, alpha 4 JBrowse link 5 145,374,688 145,377,221 RGD:6480464
G Glra1 glycine receptor, alpha 1 JBrowse link 10 40,851,955 40,954,364 RGD:6480464
G Gmfb glia maturation factor, beta JBrowse link 15 23,597,846 23,611,541 RGD:6480464
G Gnb5 G protein subunit beta 5 JBrowse link 8 82,248,951 82,286,493 RGD:6480464
G Gnl3 G protein nucleolar 3 JBrowse link 16 7,097,580 7,103,518 RGD:6480464
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:6480464
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:6480464
G Gphn gephyrin JBrowse link 6 101,327,874 101,859,169 RGD:6480464
G Gprc5b G protein-coupled receptor, class C, group 5, member B JBrowse link 1 188,688,743 188,713,724 RGD:6480464
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:6480464
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:6480464
G Gys2 glycogen synthase 2 JBrowse link 4 176,638,632 176,679,805 RGD:6480464
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:6480464
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:6480464
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 14 11,256,163 11,274,684 RGD:6480464
G Hoxa4 homeo box A4 JBrowse link 4 82,158,234 82,160,317 RGD:6480464
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 JBrowse link 19 50,246,404 50,317,892 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Htt huntingtin JBrowse link 14 81,105,139 81,254,637 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:6480464
G Ifrd1 interferon-related developmental regulator 1 JBrowse link 6 60,132,025 60,151,354 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Inhba inhibin subunit beta A JBrowse link 17 51,894,869 51,919,998 RGD:6480464
G Klf15 Kruppel-like factor 15 JBrowse link 4 122,364,688 122,377,690 RGD:6480464
G Klf9 Kruppel-like factor 9 JBrowse link 1 240,908,483 240,933,198 RGD:6480464
G Limk2 LIM domain kinase 2 JBrowse link 14 83,564,048 83,641,996 RGD:6480464
G Lox lysyl oxidase JBrowse link 18 47,500,320 47,577,819 RGD:6480464
G Mafb MAF bZIP transcription factor B JBrowse link 3 156,338,993 156,340,913 RGD:6480464
G Map2k3 mitogen activated protein kinase kinase 3 JBrowse link 10 45,089,455 45,110,802 RGD:6480464
G Map2k6 mitogen-activated protein kinase kinase 6 JBrowse link 10 98,707,160 98,823,054 RGD:6480464
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:6480464
G Map7 microtubule-associated protein 7 JBrowse link 1 15,620,665 15,748,203 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mat1a methionine adenosyltransferase 1A JBrowse link 16 18,690,649 18,709,135 RGD:6480464
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:6480464
G Mfsd2a major facilitator superfamily domain containing 2A JBrowse link 5 140,642,865 140,657,759 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 JBrowse link 4 117,488,089 117,492,315 RGD:6480464
G Neu1 neuraminidase 1 JBrowse link 20 4,610,995 4,615,258 RGD:6480464
G Nfil3 nuclear factor, interleukin 3 regulated JBrowse link 17 12,261,102 12,276,316 RGD:6480464
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:6480464
G Noct nocturnin JBrowse link 2 140,286,661 140,306,869 RGD:6480464
G Nostrin nitric oxide synthase trafficking JBrowse link 3 55,369,282 55,433,840 RGD:6480464
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:6480464
G Omd osteomodulin JBrowse link 17 15,476,100 15,484,324 RGD:6480464
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:6480464
G Osgin1 oxidative stress induced growth inhibitor 1 JBrowse link 19 52,056,808 52,085,491 RGD:6480464
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:6480464
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:6480464
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:6480464
G Pdgfd platelet derived growth factor D JBrowse link 8 4,441,010 4,666,754 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:6480464
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 JBrowse link 19 597,427 601,556 RGD:6480464
G Per2 period circadian regulator 2 JBrowse link 9 98,555,154 98,597,362 RGD:6480464
G Pex14 peroxisomal biogenesis factor 14 JBrowse link 5 165,782,895 165,918,445 RGD:6480464
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 JBrowse link 17 70,632,778 70,713,736 RGD:6480464
G Pkia cAMP-dependent protein kinase inhibitor alpha JBrowse link 2 96,593,185 96,668,222 RGD:6480464
G Plk3 polo-like kinase 3 JBrowse link 5 135,997,725 136,002,900 RGD:6480464
G Pnpla7 patatin-like phospholipase domain containing 7 JBrowse link 3 2,182,191 2,261,890 RGD:6480464
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B JBrowse link 16 60,415,192 60,427,498 RGD:6480464
G Ptp4a1 protein tyrosine phosphatase 4A1 JBrowse link 9 37,223,363 37,254,222 RGD:6480464
G Ptprr protein tyrosine phosphatase, receptor type, R JBrowse link 7 59,039,717 59,325,925 RGD:6480464
G Pxmp4 peroxisomal membrane protein 4 JBrowse link 3 150,091,646 150,108,893 RGD:6480464
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase JBrowse link 4 147,532,040 147,592,769 RGD:6480464
G Rapgef4 Rap guanine nucleotide exchange factor 4 JBrowse link 3 58,632,338 58,925,127 RGD:6480464
G Rbm3 RNA binding motif protein 3 JBrowse link X 15,098,880 15,102,344 RGD:6480464
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:6480464
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:6480464
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 6 42,180,864 42,289,910 RGD:6480464
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:6480464
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 2 218,654,406 218,658,761 RGD:6480464
G Scn2b sodium voltage-gated channel beta subunit 2 JBrowse link 8 49,419,003 49,431,110 RGD:6480464
G Scnn1a sodium channel epithelial 1 subunit alpha JBrowse link 4 157,834,339 157,860,472 RGD:6480464
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:6480464
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 JBrowse link 19 50,207,960 50,220,455 RGD:6480464
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:6480464
G Sik1 salt-inducible kinase 1 JBrowse link 20 10,670,747 10,680,279 RGD:6480464
G Slc13a2 solute carrier family 13 member 2 JBrowse link 10 65,664,665 65,692,046 RGD:6480464
G Slc17a6 solute carrier family 17 member 6 JBrowse link 1 106,980,463 107,038,717 RGD:6480464
G Slc20a1 solute carrier family 20 member 1 JBrowse link 3 121,725,204 121,739,160 RGD:6480464
G Slc25a25 solute carrier family 25 member 25 JBrowse link 3 11,442,396 11,476,186 RGD:6480464
G Slc25a32 solute carrier family 25 member 32 JBrowse link 7 77,983,885 78,005,058 RGD:6480464
G Slc28a2 solute carrier family 28 member 2 JBrowse link 3 114,355,003 114,647,382 RGD:6480464
G Slc38a2 solute carrier family 38, member 2 JBrowse link 7 138,088,654 138,100,869 RGD:6480464
G Slc3a2 solute carrier family 3 member 2 JBrowse link 1 224,906,566 224,921,029 RGD:6480464
G Slc6a9 solute carrier family 6 member 9 JBrowse link 5 136,669,674 136,703,702 RGD:6480464
G Slc7a10 solute carrier family 7 member 10 JBrowse link 1 91,432,952 91,448,566 RGD:6480464
G Slc7a2 solute carrier family 7 member 2 JBrowse link 16 54,459,409 54,513,349 RGD:6480464
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:6480464
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:6480464
G Sqle squalene epoxidase JBrowse link 7 99,609,929 99,624,803 RGD:6480464
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:6480464
G Susd3 sushi domain containing 3 JBrowse link 17 15,814,132 15,830,328 RGD:6480464
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:6480464
G Tef TEF transcription factor, PAR bZIP family member JBrowse link 7 123,033,971 123,058,606 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Trib3 tribbles pseudokinase 3 JBrowse link 3 147,814,056 147,819,650 RGD:6480464
G Tuba1a tubulin, alpha 1A JBrowse link 7 140,637,287 140,640,953 RGD:6480464
G Tuba1b tubulin, alpha 1B JBrowse link 7 140,614,746 140,617,721 RGD:6480464
G Tuba3b tubulin, alpha 3B JBrowse link 4 179,905,154 179,910,703 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 JBrowse link 9 95,274,707 95,302,822 RGD:6480464
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Usp2 ubiquitin specific peptidase 2 JBrowse link 8 48,403,985 48,432,525 RGD:6480464
G Zfp354a zinc finger protein 354A JBrowse link 10 36,586,495 36,600,172 RGD:6480464
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                  main group element atom 19655
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.