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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sevoflurane
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Accession:CHEBI:9130 term browser browse the term
Definition:An ether compound having fluoromethyl and 1,1,1,3,3,3-hexafluoroisopropyl as the two alkyl groups.
Synonyms:related_synonym: 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane;   Formula=C4H3F7O;   InChI=1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2;   InChIKey=DFEYYRMXOJXZRJ-UHFFFAOYSA-N;   SMILES=FCOC(C(F)(F)F)C(F)(F)F;   Sevofluran;   Sevoflurano;   Sevofluranum
 xref: Beilstein:2041023;   CAS:28523-86-6;   DrugBank:DB01236;   Drug_Central:2439;   KEGG:C07520;   KEGG:D00547
 xref_mesh: MESH:C009250
 xref: Patent:DE1954268;   Patent:US3689571;   Wikipedia:Sevoflurane


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sevoflurane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aass aminoadipate-semialdehyde synthase affects expression EXP sevoflurane affects the expression of AASS mRNA CTD PMID:15967596 NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136 		JBrowse link
G Aatf apoptosis antagonizing transcription factor affects expression EXP sevoflurane affects the expression of AATF mRNA CTD PMID:15967596 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression EXP sevoflurane affects the expression of ABCB1A mRNA CTD PMID:15967596 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects expression EXP sevoflurane affects the expression of ABCC2 mRNA CTD PMID:15967596 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Aco2 aconitase 2 affects expression EXP sevoflurane affects the expression of ACO2 mRNA CTD PMID:15967596 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 affects expression EXP sevoflurane affects the expression of ADAMTS1 mRNA CTD PMID:15967596 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 EXP sevoflurane results in increased phosphorylation of AKT1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sevoflurane results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sevoflurane results in increased phosphorylation of AKT1 protein]		 CTD PMID:19881297 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 affects expression EXP sevoflurane affects the expression of ALAS1 mRNA CTD PMID:15967596 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 affects expression EXP sevoflurane affects the expression of AMD1 mRNA CTD PMID:15967596 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476 		JBrowse link
G App amyloid beta precursor protein affects cleavage
multiple interactions
increases expression		 ISO sevoflurane affects the cleavage of APP protein
APP protein modified form promotes the reaction [sevoflurane results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [sevoflurane affects the cleavage of APP protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [sevoflurane results in increased expression of APP protein modified form]
sevoflurane promotes the reaction [CASP3 protein results in increased cleavage of APP protein]		 CTD PMID:19433662 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) affects expression EXP sevoflurane affects the expression of AQP3 mRNA CTD PMID:15967596 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression EXP sevoflurane affects the expression of ARC mRNA CTD PMID:15967596 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like affects expression EXP sevoflurane affects the expression of ARNTL mRNA CTD PMID:15967596 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Asl argininosuccinate lyase affects expression EXP sevoflurane affects the expression of ASL mRNA CTD PMID:15967596 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Atf2 activating transcription factor 2 increases phosphorylation ISO sevoflurane results in increased phosphorylation of ATF2 protein CTD PMID:18349187 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A affects expression EXP sevoflurane affects the expression of AVPR1A mRNA CTD PMID:15967596 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP sevoflurane affects the expression of BAAT mRNA CTD PMID:15967596 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bace1 beta-secretase 1 increases expression ISO sevoflurane results in increased expression of BACE1 protein CTD PMID:19433662 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP
ISO		 Nimodipine inhibits the reaction [Sevoflurane results in increased expression of BAX protein] CTD PMID:33171207 PMID:33928466 PMID:35110470 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 EXP Nimodipine inhibits the reaction [Sevoflurane results in decreased expression of BCL2 protein] CTD PMID:33171207 PMID:35110470 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 affects expression EXP sevoflurane affects the expression of BHLHE41 mRNA CTD PMID:15967596 NCBI chr 4:178,833,085...178,838,685
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions ISO sevoflurane inhibits the reaction [CALCA protein modified form results in increased abundance of Cyclic AMP] CTD PMID:15297469 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression		 ISO
EXP		 sevoflurane results in increased activity of CASP3 protein
APP protein modified form promotes the reaction [sevoflurane results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [sevoflurane results in increased cleavage of CASP3 protein]; L 685458 inhibits the reaction [sevoflurane results in increased cleavage of CASP3 protein]; sevoflurane results in increased cleavage of and results in increased activity of CASP3 protein
sevoflurane results in increased expression of CASP3 mRNA
Sevoflurane results in increased cleavage of CASP3 protein
Sevoflurane promotes the reaction [CASP3 protein results in increased cleavage of APP protein]; Sevoflurane results in increased cleavage of and results in increased activity of CASP3 protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in increased cleavage of CASP3 protein]; Nimodipine inhibits the reaction [Sevoflurane results in increased expression of CASP3 protein modified form]; Roscovitine inhibits the reaction [Sevoflurane results in increased cleavage of CASP3 protein]		 CTD PMID:15915027 PMID:16678324 PMID:18349187 PMID:18852026 PMID:19212262 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity ISO sevoflurane results in increased activity of CASP7 protein CTD PMID:16678324 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression		 EXP Nimodipine inhibits the reaction [Sevoflurane results in increased expression of CASP9 protein modified form] CTD PMID:33171207 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cckbr cholecystokinin B receptor affects expression EXP sevoflurane affects the expression of CCKBR mRNA CTD PMID:15967596 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP sevoflurane results in decreased expression of CCL2 mRNA CTD PMID:15564938 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnd1 cyclin D1 affects expression EXP sevoflurane affects the expression of CCND1 mRNA CTD PMID:15967596 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd274 CD274 molecule decreases expression ISO Sevoflurane results in decreased expression of CD274 mRNA; Sevoflurane results in decreased expression of CD274 protein CTD PMID:34018092 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cdh17 cadherin 17 affects expression EXP sevoflurane affects the expression of CDH17 mRNA CTD PMID:15967596 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 EXP Roscovitine inhibits the reaction [Sevoflurane results in increased expression of CDKN1A protein] CTD PMID:33548343 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta affects expression EXP sevoflurane affects the expression of CEBPB mRNA CTD PMID:15967596 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Ces2c carboxylesterase 2C affects expression EXP sevoflurane affects the expression of CES2C mRNA CTD PMID:15967596 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790 		JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 affects expression EXP sevoflurane affects the expression of CGRRF1 mRNA CTD PMID:15967596 NCBI chr15:20,088,564...20,109,042
Ensembl chr15:20,088,571...20,109,037 		JBrowse link
G Chka choline kinase alpha affects expression EXP sevoflurane affects the expression of CHKA mRNA CTD PMID:15967596 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Cnga4 cyclic nucleotide gated channel subunit alpha 4 affects expression EXP sevoflurane affects the expression of CNGA4 mRNA CTD PMID:15967596 NCBI chr 1:159,752,357...159,756,369
Ensembl chr 1:159,752,357...159,756,375 		JBrowse link
G Cntn2 contactin 2 affects expression EXP sevoflurane affects the expression of CNTN2 mRNA CTD PMID:15967596 NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression EXP sevoflurane affects the expression of CPT1A mRNA CTD PMID:15967596 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression
multiple interactions
decreases phosphorylation		 EXP Sevoflurane results in decreased expression of CREB1 mRNA
Vorinostat inhibits the reaction [Sevoflurane results in decreased expression of CREB1 mRNA]; Vorinostat inhibits the reaction [Sevoflurane results in decreased phosphorylation of CREB1 protein]		 CTD PMID:30842370 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator affects expression EXP sevoflurane affects the expression of CREM mRNA CTD PMID:15967596 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 affects expression EXP sevoflurane affects the expression of CRY2 mRNA CTD PMID:15967596 NCBI chr 3:78,374,995...78,405,001
Ensembl chr 3:78,374,995...78,404,965 		JBrowse link
G Ctsl cathepsin L affects expression EXP sevoflurane affects the expression of CTSL mRNA CTD PMID:15967596 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression
multiple interactions		 EXP sevoflurane results in decreased expression of CXCL1 mRNA
MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]]		 CTD PMID:15564938 PMID:32147387 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP sevoflurane results in decreased expression of CXCL10 mRNA CTD PMID:15564938 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
decreases expression		 EXP sevoflurane results in increased expression of CXCL2 mRNA
sevoflurane results in decreased expression of CXCL2 mRNA		 CTD PMID:10422944 PMID:15564938 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression		 EXP Nimodipine inhibits the reaction [Sevoflurane results in increased expression of CYCS protein] CTD PMID:33171207 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 affects expression EXP sevoflurane affects the expression of CYP2B12 mRNA CTD PMID:15967596 NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression EXP sevoflurane affects the expression of CYP2B2 mRNA CTD PMID:15967596 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 affects expression EXP sevoflurane affects the expression of CYP2B21 mRNA CTD PMID:15967596 NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects expression EXP sevoflurane affects the expression of CYP2C mRNA; sevoflurane affects the expression of CYP2C11 mRNA CTD PMID:15967596 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing ISO CYP2E1 protein results in increased metabolism of sevoflurane CTD PMID:7879937 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP sevoflurane affects the expression of CYP2F4 mRNA CTD PMID:15967596 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of Sevoflurane CTD PMID:7879937 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 affects expression EXP sevoflurane affects the expression of CYP7A1 mRNA CTD PMID:15967596 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dbn1 drebrin 1 decreases expression
multiple interactions		 EXP Sevoflurane results in decreased expression of DBN1 protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of DBN1 protein]; DPYSL2 protein affects the reaction [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of DBN1 protein]]; DPYSL2 protein affects the reaction [Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of DBN1 protein]]; Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of DBN1 protein]		 CTD PMID:33548343 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor affects expression EXP sevoflurane affects the expression of DBP mRNA CTD PMID:15967596 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Dhx30 DExH-box helicase 30 affects expression EXP sevoflurane affects the expression of DHX30 mRNA CTD PMID:15967596 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 decreases expression
multiple interactions		 EXP Sevoflurane results in decreased expression of DLG4 protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of DLG4 protein]; DPYSL2 protein affects the reaction [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of DLG4 protein]]; DPYSL2 protein affects the reaction [Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of DLG4 protein]]; Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of DLG4 protein]		 CTD PMID:33548343 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dnase2b deoxyribonuclease 2 beta affects expression EXP sevoflurane affects the expression of DNASE2B mRNA CTD PMID:15967596 NCBI chr 2:235,470,915...235,515,211
Ensembl chr 2:235,470,919...235,486,295 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions EXP sevoflurane inhibits the reaction [Oxygen deficiency results in increased expression of DNM1L protein] CTD PMID:27684054 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions
increases phosphorylation		 EXP 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in increased phosphorylation of DPYSL2 protein]; DPYSL2 protein affects the reaction [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of DBN1 protein]]; DPYSL2 protein affects the reaction [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of DLG4 protein]]; DPYSL2 protein affects the reaction [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]]; DPYSL2 protein affects the reaction [Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of DBN1 protein]]; DPYSL2 protein affects the reaction [Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of DLG4 protein]]; DPYSL2 protein affects the reaction [Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]]; Roscovitine inhibits the reaction [Sevoflurane results in increased phosphorylation of DPYSL2 protein] CTD PMID:33548343 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dusp16 dual specificity phosphatase 16 affects expression EXP sevoflurane affects the expression of DUSP16 mRNA CTD PMID:15967596 NCBI chr 4:167,546,780...167,629,949
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp6 dual specificity phosphatase 6 affects expression EXP sevoflurane affects the expression of DUSP6 mRNA CTD PMID:15967596 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 affects expression EXP sevoflurane affects the expression of DYNLL1 mRNA CTD PMID:15967596 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741 		JBrowse link
G Edn1 endothelin 1 affects expression EXP sevoflurane affects the expression of EDN1 mRNA CTD PMID:15967596 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Efna1 ephrin A1 affects expression EXP sevoflurane affects the expression of EFNA1 mRNA CTD PMID:15967596 NCBI chr 2:174,681,676...174,690,306
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Egr1 early growth response 1 affects expression EXP sevoflurane affects the expression of EGR1 mRNA CTD PMID:15967596 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 affects expression EXP sevoflurane affects the expression of EGR2 mRNA CTD PMID:15967596 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression EXP sevoflurane affects the expression of EPHX1 mRNA CTD PMID:15967596 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Fads2 fatty acid desaturase 2 affects expression EXP sevoflurane affects the expression of FADS2 mRNA CTD PMID:15967596 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 affects expression EXP sevoflurane affects the expression of FMO2 mRNA CTD PMID:15967596 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Foxa3 forkhead box A3 affects expression EXP sevoflurane affects the expression of FOXA3 mRNA CTD PMID:15967596 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155 		JBrowse link
G Fst follistatin affects expression EXP sevoflurane affects the expression of FST mRNA CTD PMID:15967596 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO sevoflurane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of GABBR1 protein] CTD PMID:10683198 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:37,096,995...37,230,030
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO sevoflurane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 affects expression EXP sevoflurane affects the expression of GABRG2 mRNA CTD PMID:15967596 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gad2 glutamate decarboxylase 2 increases expression ISO Sevoflurane results in increased expression of GAD2 mRNA; Sevoflurane results in increased expression of GAD2 protein CTD PMID:30502404 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha affects expression EXP sevoflurane affects the expression of GADD45A mRNA CTD PMID:15967596 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gch1 GTP cyclohydrolase 1 affects expression EXP sevoflurane affects the expression of GCH1 mRNA CTD PMID:15967596 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gck glucokinase affects expression EXP sevoflurane affects the expression of GCK mRNA CTD PMID:15967596 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gja4 gap junction protein, alpha 4 affects expression EXP sevoflurane affects the expression of GJA4 mRNA CTD PMID:15967596 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925 		JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO sevoflurane promotes the reaction [Glycine Agents results in increased activity of GLRA1 protein] CTD PMID:10683198 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162 		JBrowse link
G Gmfb glia maturation factor, beta affects expression EXP sevoflurane affects the expression of GMFB mRNA CTD PMID:15967596 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331 		JBrowse link
G Gnb5 G protein subunit beta 5 affects expression EXP sevoflurane affects the expression of GNB5 mRNA CTD PMID:15967596 NCBI chr 8:76,076,227...76,104,151
Ensembl chr 8:76,073,306...76,105,069 		JBrowse link
G Gnl3 G protein nucleolar 3 affects expression EXP sevoflurane affects the expression of GNL3 mRNA CTD PMID:15967596 NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 affects expression EXP sevoflurane affects the expression of GOT1 mRNA CTD PMID:15967596 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial affects expression EXP sevoflurane affects the expression of GPAM mRNA CTD PMID:15967596 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gphn gephyrin increases expression ISO Sevoflurane results in increased expression of GPHN mRNA; Sevoflurane results in increased expression of GPHN protein CTD PMID:30502404 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B affects expression EXP sevoflurane affects the expression of GPRC5B mRNA CTD PMID:15967596 NCBI chr 1:173,316,398...173,340,951
Ensembl chr 1:173,316,907...173,340,932 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 increases expression ISO Sevoflurane results in increased expression of GRIA1 protein CTD PMID:30502404 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression ISO Sevoflurane results in increased expression of GRIA2 protein CTD PMID:30502404 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions
decreases expression		 ISO GRIN2A protein affects the susceptibility to [Nitrous Oxide co-treated with sevoflurane]
Sevoflurane results in decreased expression of GRIN2A mRNA		 CTD PMID:15731593 PMID:33928466 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
decreases expression		 EXP Vorinostat inhibits the reaction [Sevoflurane results in decreased expression of GRIN2B mRNA]; Vorinostat inhibits the reaction [Sevoflurane results in decreased expression of GRIN2B protein]
Sevoflurane results in decreased expression of GRIN2B mRNA; Sevoflurane results in decreased expression of GRIN2B protein		 CTD PMID:30842370 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation		 EXP 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein]; Lithium Chloride inhibits the reaction [Sevoflurane results in decreased phosphorylation of GSK3B protein] CTD PMID:20807582 PMID:33548343 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 affects expression EXP Sevoflurane affects the expression of GSTA3 mRNA CTD PMID:15967596 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gys2 glycogen synthase 2 affects expression EXP sevoflurane affects the expression of GYS2 mRNA CTD PMID:15967596 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228 		JBrowse link
G Hdac2 histone deacetylase 2 multiple interactions
increases expression		 EXP Vorinostat inhibits the reaction [Sevoflurane results in increased expression of HDAC2 mRNA]; Vorinostat inhibits the reaction [Sevoflurane results in increased expression of HDAC2 protein]
Sevoflurane results in increased expression of HDAC2 mRNA; Sevoflurane results in increased expression of HDAC2 protein		 CTD PMID:30842370 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hhex hematopoietically expressed homeobox affects expression EXP sevoflurane affects the expression of HHEX mRNA CTD PMID:15967596 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D affects expression EXP sevoflurane affects the expression of HNRNPD mRNA CTD PMID:15967596 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hoxa4 homeo box A4 affects expression EXP sevoflurane affects the expression of HOXA4 mRNA CTD PMID:15967596 NCBI chr 4:81,289,677...81,291,685
Ensembl chr 4:81,289,682...81,291,685 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects expression EXP sevoflurane affects the expression of HSD17B2 mRNA CTD PMID:15967596 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects expression EXP sevoflurane affects the expression of HSPA8 mRNA CTD PMID:15967596 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Htt huntingtin multiple interactions ISO sevoflurane promotes the reaction [HTT protein mutant form binds to HTT protein mutant form] CTD PMID:21059370 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions		 EXP sevoflurane results in decreased expression of ICAM1 mRNA; sevoflurane results in decreased expression of ICAM1 protein
MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]		 CTD PMID:15564938 PMID:32147387 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 affects expression EXP sevoflurane affects the expression of ID2 mRNA CTD PMID:15967596 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 affects expression EXP sevoflurane affects the expression of IFRD1 mRNA CTD PMID:15967596 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion		 EXP sevoflurane results in increased expression of IL1B mRNA
Sevoflurane results in increased secretion of IL1B protein		 CTD PMID:10422944 PMID:35110470 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases secretion EXP Sevoflurane results in increased secretion of IL6 protein CTD PMID:35110470 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A affects expression EXP sevoflurane affects the expression of INHBA mRNA CTD PMID:15967596 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Klf15 Kruppel-like factor 15 affects expression EXP sevoflurane affects the expression of KLF15 mRNA CTD PMID:15967596 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Klf9 Kruppel-like factor 9 affects expression EXP sevoflurane affects the expression of KLF9 mRNA CTD PMID:15967596 NCBI chr 1:220,700,108...220,725,029
Ensembl chr 1:220,700,108...220,725,037 		JBrowse link
G Lcn2 lipocalin 2 increases secretion ISO Sevoflurane results in increased secretion of LCN2 protein CTD PMID:30538007 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Limk2 LIM domain kinase 2 affects expression EXP sevoflurane affects the expression of LIMK2 mRNA CTD PMID:15967596 NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007 		JBrowse link
G Lox lysyl oxidase affects expression EXP sevoflurane affects the expression of LOX mRNA CTD PMID:15967596 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Mafb MAF bZIP transcription factor B affects expression EXP sevoflurane affects the expression of MAFB mRNA CTD PMID:15967596 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases phosphorylation ISO sevoflurane results in increased phosphorylation of MAP2K3 protein CTD PMID:18349187 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 increases phosphorylation ISO sevoflurane results in increased phosphorylation of MAP2K6 protein CTD PMID:18349187 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 increases phosphorylation ISO sevoflurane results in increased phosphorylation of MAP3K5 protein CTD PMID:18349187 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map7 microtubule-associated protein 7 affects expression EXP sevoflurane affects the expression of MAP7 mRNA CTD PMID:15967596 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sevoflurane results in increased phosphorylation of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sevoflurane results in increased phosphorylation of MAPK1 protein] CTD PMID:19881297 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sevoflurane results in increased phosphorylation of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sevoflurane results in increased phosphorylation of MAPK3 protein] CTD PMID:19881297 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mat1a methionine adenosyltransferase 1A affects expression EXP sevoflurane affects the expression of MAT1A mRNA CTD PMID:15967596 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit decreases expression ISO Sevoflurane results in decreased expression of METTL3 mRNA CTD PMID:33928466 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mfn2 mitofusin 2 multiple interactions EXP sevoflurane inhibits the reaction [Oxygen deficiency inhibits the reaction [Glucose results in increased expression of MFN2 protein]]; sevoflurane inhibits the reaction [Oxygen deficiency results in decreased expression of MFN2 protein] CTD PMID:27684054 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A affects expression EXP sevoflurane affects the expression of MFSD2A mRNA CTD PMID:15967596 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690 		JBrowse link
G Mir34a microRNA 34a multiple interactions
increases response to substance		 EXP MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in decreased expression of MIR34A mRNA]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in decreased expression of MIR34A mRNA]]
MIR34A mRNA results in increased susceptibility to Sevoflurane		 CTD PMID:32147387 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]] CTD PMID:32147387 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase decreases activity
multiple interactions		 EXP sevoflurane results in decreased activity of MPO protein
MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]		 CTD PMID:15564938 PMID:32147387 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nat8f3 N-acetyltransferase 8 (GCN5-related) family member 3 affects expression EXP sevoflurane affects the expression of NAT8F3 mRNA CTD PMID:15967596 NCBI chr 4:118,241,792...118,246,010
Ensembl chr 4:118,239,304...118,285,500 		JBrowse link
G Neu1 neuraminidase 1 affects expression EXP sevoflurane affects the expression of NEU1 mRNA CTD PMID:15967596 NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated affects expression EXP sevoflurane affects the expression of NFIL3 mRNA CTD PMID:15967596 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858 		JBrowse link
G Ngfr nerve growth factor receptor affects expression EXP sevoflurane affects the expression of NGFR mRNA CTD PMID:15967596 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nlgn1 neuroligin 1 decreases expression ISO Sevoflurane results in decreased expression of NLGN1 mRNA CTD PMID:33928466 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Noct nocturnin affects expression EXP sevoflurane affects the expression of NOCT mRNA CTD PMID:15967596 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] CTD PMID:32147387 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nostrin nitric oxide synthase trafficking affects expression EXP sevoflurane affects the expression of NOSTRIN mRNA CTD PMID:15967596 NCBI chr 3:53,904,746...53,970,995
Ensembl chr 3:53,904,827...53,970,988 		JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression EXP Sevoflurane results in increased expression of NOVA1 mRNA; Sevoflurane results in increased expression of NOVA1 protein CTD PMID:35110470 NCBI chr 6:63,780,105...63,905,950
Ensembl chr 6:63,783,489...63,906,289 		JBrowse link
G Nox1 NADPH oxidase 1 increases expression EXP Sevoflurane results in increased expression of NOX1 protein CTD PMID:35110470 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nox4 NADPH oxidase 4 increases expression EXP Sevoflurane results in increased expression of NOX4 protein CTD PMID:35110470 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nptx1 neuronal pentraxin 1 decreases expression ISO Sevoflurane results in decreased expression of NPTX1 mRNA CTD PMID:33928466 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 affects expression EXP sevoflurane affects the expression of NR1D1 mRNA CTD PMID:15967596 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects expression EXP sevoflurane affects the expression of NR1I2 mRNA CTD PMID:15967596 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects expression EXP sevoflurane affects the expression of NR4A1 mRNA CTD PMID:15967596 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Omd osteomodulin affects expression EXP sevoflurane affects the expression of OMD mRNA CTD PMID:15967596 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP sevoflurane inhibits the reaction [Oxygen deficiency results in decreased expression of OPA1 protein] CTD PMID:27684054 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 affects expression EXP sevoflurane affects the expression of OSGIN1 mRNA CTD PMID:15967596 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516 		JBrowse link
G P2rx7 purinergic receptor P2X 7 affects expression EXP sevoflurane affects the expression of P2RX7 mRNA CTD PMID:15967596 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pde3b phosphodiesterase 3B affects expression EXP sevoflurane affects the expression of PDE3B mRNA CTD PMID:15967596 NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334 		JBrowse link
G Pde4b phosphodiesterase 4B affects expression EXP sevoflurane affects the expression of PDE4B mRNA CTD PMID:15967596 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdgfd platelet derived growth factor D affects expression EXP sevoflurane affects the expression of PDGFD mRNA CTD PMID:15967596 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 affects expression EXP sevoflurane affects the expression of PDK4 mRNA CTD PMID:15967596 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pdp2 pyruvate dehydrogenase phosphatase catalytic subunit 2 affects expression EXP sevoflurane affects the expression of PDP2 mRNA CTD PMID:15967596 NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074 		JBrowse link
G Per2 period circadian regulator 2 affects expression EXP sevoflurane affects the expression of PER2 mRNA CTD PMID:15967596 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459 		JBrowse link
G Pex14 peroxisomal biogenesis factor 14 affects expression EXP sevoflurane affects the expression of PEX14 mRNA CTD PMID:15967596 NCBI chr 5:159,399,776...159,536,260
Ensembl chr 5:159,399,776...159,536,272 		JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 affects expression EXP sevoflurane affects the expression of PFKFB3 mRNA CTD PMID:15967596 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125 		JBrowse link
G Pkia cAMP-dependent protein kinase inhibitor alpha affects expression EXP sevoflurane affects the expression of PKIA mRNA CTD PMID:15967596 NCBI chr 2:94,398,869...94,473,638
Ensembl chr 2:94,398,869...94,414,282 		JBrowse link
G Plk3 polo-like kinase 3 affects expression EXP sevoflurane affects the expression of PLK3 mRNA CTD PMID:15967596 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 affects expression EXP sevoflurane affects the expression of PNPLA7 mRNA CTD PMID:15967596 NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497 		JBrowse link
G Por cytochrome p450 oxidoreductase affects expression EXP sevoflurane affects the expression of POR mRNA CTD PMID:15967596 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects expression EXP sevoflurane affects the expression of PPARA mRNA CTD PMID:15967596 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B affects expression EXP sevoflurane affects the expression of PPP1R3B mRNA CTD PMID:15967596 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]] CTD PMID:32147387 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 affects expression EXP sevoflurane affects the expression of PTP4A1 mRNA CTD PMID:15967596 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964 		JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R affects expression EXP sevoflurane affects the expression of PTPRR mRNA CTD PMID:15967596 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603 		JBrowse link
G Pxmp4 peroxisomal membrane protein 4 affects expression EXP sevoflurane affects the expression of PXMP4 mRNA CTD PMID:15967596 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase affects expression EXP sevoflurane affects the expression of RAF1 mRNA CTD PMID:15967596 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 affects expression EXP sevoflurane affects the expression of RAPGEF4 mRNA CTD PMID:15967596 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rbm3 RNA binding motif protein 3 affects expression EXP sevoflurane affects the expression of RBM3 mRNA CTD PMID:15967596 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580 		JBrowse link
G Rgcc regulator of cell cycle affects expression EXP sevoflurane affects the expression of RGCC mRNA CTD PMID:15967596 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP sevoflurane inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of RHOA protein] CTD PMID:12960549 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 multiple interactions EXP sevoflurane inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) affects the localization of ROCK2 protein] CTD PMID:12960549 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G S100a9 S100 calcium binding protein A9 affects expression EXP sevoflurane affects the expression of S100A9 mRNA CTD PMID:15967596 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP sevoflurane affects the expression of S1PR1 mRNA CTD PMID:15967596 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 affects expression EXP sevoflurane affects the expression of SCN2B mRNA CTD PMID:15967596 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha affects expression EXP sevoflurane affects the expression of SCNN1A mRNA CTD PMID:15967596 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Sdc4 syndecan 4 affects expression EXP sevoflurane affects the expression of SDC4 mRNA CTD PMID:15967596 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 affects expression EXP sevoflurane affects the expression of SDR42E1 mRNA CTD PMID:15967596 NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 affects expression EXP sevoflurane affects the expression of SGK1 mRNA CTD PMID:15967596 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sik1 salt-inducible kinase 1 affects expression EXP sevoflurane affects the expression of SIK1 mRNA CTD PMID:15967596 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Slc13a2 solute carrier family 13 member 2 affects expression EXP sevoflurane affects the expression of SLC13A2 mRNA CTD PMID:15967596 NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 affects expression EXP sevoflurane affects the expression of SLC17A6 mRNA CTD PMID:15967596 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 affects expression EXP sevoflurane affects the expression of SLC20A1 mRNA CTD PMID:15967596 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc25a25 solute carrier family 25 member 25 affects expression EXP sevoflurane affects the expression of SLC25A25 mRNA CTD PMID:15967596 NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216 		JBrowse link
G Slc25a32 solute carrier family 25 member 32 affects expression EXP sevoflurane affects the expression of SLC25A32 mRNA CTD PMID:15967596 NCBI chr 7:70,142,958...70,160,726
Ensembl chr 7:70,142,964...70,160,770 		JBrowse link
G Slc28a2 solute carrier family 28 member 2 affects expression EXP sevoflurane affects the expression of SLC28A2 mRNA CTD PMID:15967596 NCBI chr 3:109,324,815...109,387,702
Ensembl chr 3:109,366,996...109,387,702 		JBrowse link
G Slc38a2 solute carrier family 38, member 2 affects expression EXP sevoflurane affects the expression of SLC38A2 mRNA CTD PMID:15967596 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 affects expression EXP sevoflurane affects the expression of SLC3A2 mRNA CTD PMID:15967596 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 affects expression EXP sevoflurane affects the expression of SLC6A9 mRNA CTD PMID:15967596 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Slc7a10 solute carrier family 7 member 10 affects expression EXP sevoflurane affects the expression of SLC7A10 mRNA CTD PMID:15967596 NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071 		JBrowse link
G Slc7a2 solute carrier family 7 member 2 affects expression EXP sevoflurane affects the expression of SLC7A2 mRNA CTD PMID:15967596 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784 		JBrowse link
G Smad3 SMAD family member 3 affects response to substance
multiple interactions		 ISO SMAD3 protein affects the susceptibility to sevoflurane
TGFB1 protein affects the reaction [sevoflurane affects the localization of SMAD3 protein]		 CTD PMID:18434384 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 decreases activity ISO sevoflurane results in decreased activity of SMPD1 protein CTD PMID:19572936 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Sqle squalene epoxidase affects expression EXP sevoflurane affects the expression of SQLE mRNA CTD PMID:15967596 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions
decreases response to substance		 EXP MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]]; MIR34A mRNA promotes the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 protein]]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 protein]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in decreased expression of MIR34A mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 protein]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]]; STAT1 inhibits the reaction [Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]
STAT1 results in decreased susceptibility to Sevoflurane		 CTD PMID:32147387 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 affects expression EXP sevoflurane affects the expression of SULT1A1 mRNA CTD PMID:15967596 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Susd3 sushi domain containing 3 affects expression EXP sevoflurane affects the expression of SUSD3 mRNA CTD PMID:15967596 NCBI chr17:15,400,845...15,417,851
Ensembl chr17:15,400,845...15,417,044 		JBrowse link
G Syp synaptophysin decreases expression
multiple interactions		 EXP
ISO		 Sevoflurane results in decreased expression of SYP protein
3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]; DPYSL2 protein affects the reaction [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]]; DPYSL2 protein affects the reaction [Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]]; Roscovitine inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]
YTHDF1 protein inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]		 CTD PMID:33548343 PMID:33928466 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Syt11 synaptotagmin 11 increases expression ISO Sevoflurane results in increased expression of SYT11 mRNA CTD PMID:33928466 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase affects expression EXP sevoflurane affects the expression of TDO2 mRNA CTD PMID:15967596 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Tef TEF transcription factor, PAR bZIP family member affects expression EXP sevoflurane affects the expression of TEF mRNA CTD PMID:15967596 NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
affects response to substance		 ISO TGFB1 protein affects the reaction [sevoflurane affects the localization of SMAD3 protein]
TGFB1 protein affects the susceptibility to sevoflurane		 CTD PMID:18434384 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases secretion		 EXP sevoflurane results in decreased expression of TNF mRNA
Sevoflurane results in increased secretion of TNF protein		 CTD PMID:15564938 PMID:35110470 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO sevoflurane results in increased expression of TP53 mRNA CTD PMID:19572936 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trib3 tribbles pseudokinase 3 affects expression EXP sevoflurane affects the expression of TRIB3 mRNA CTD PMID:15967596 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Tuba1a tubulin, alpha 1A affects expression EXP sevoflurane affects the expression of TUBA1A mRNA CTD PMID:15967596 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tuba1b tubulin, alpha 1B affects expression EXP sevoflurane affects the expression of TUBA1B mRNA CTD PMID:15967596 NCBI chr 7:130,090,669...130,093,644
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tuba3b tubulin, alpha 3B affects expression EXP sevoflurane affects the expression of TUBA3B mRNA CTD PMID:15967596 NCBI chr 4:178,588,779...178,594,328
Ensembl chr 4:178,588,779...178,594,326 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression EXP sevoflurane affects the expression of UGT1A1 mRNA CTD PMID:15967596 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 affects expression EXP sevoflurane affects the expression of UGT1A2 mRNA; sevoflurane affects the expression of UGT1A3 mRNA CTD PMID:15967596 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 affects expression EXP sevoflurane affects the expression of UGT1A5 mRNA CTD PMID:15967596 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 affects expression EXP sevoflurane affects the expression of UGT1A6 mRNA CTD PMID:15967596 NCBI chr 9:88,747,229...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C affects expression EXP Sevoflurane affects the expression of UGT1A8 mRNA CTD PMID:15967596 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects expression EXP sevoflurane affects the expression of UGT1A9 mRNA CTD PMID:15967596 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 affects expression EXP sevoflurane affects the expression of USP2 mRNA CTD PMID:15967596 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331 		JBrowse link
G Ythdf1 YTH N(6)-methyladenosine RNA binding protein 1 multiple interactions
decreases expression		 ISO YTHDF1 protein inhibits the reaction [Sevoflurane results in decreased expression of SYP protein]
Sevoflurane results in decreased expression of YTHDF1 mRNA; Sevoflurane results in decreased expression of YTHDF1 protein		 CTD PMID:33928466 NCBI chr 3:168,024,660...168,040,172
Ensembl chr 3:168,024,663...168,040,172 		JBrowse link
G Zfp354a zinc finger protein 354A affects expression EXP sevoflurane affects the expression of ZFP354A mRNA CTD PMID:15967596 NCBI chr10:35,396,242...35,408,065
Ensembl chr10:35,396,231...35,408,068 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 20072
    role 20024
      application 19760
        pharmaceutical 19633
          drug 19633
            central nervous system drug 16573
              central nervous system depressant 16085
                sevoflurane 217
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Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19971
                    p-block element atom 19971
                      carbon group element atom 19894
                        carbon atom 19887
                          organic molecular entity 19887
                            heteroorganic entity 19577
                              organochalcogen compound 19339
                                organooxygen compound 19239
                                  ether 17003
                                    2-methoxypropane 217
                                      sevoflurane 217
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