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Gene: Cyp2b12 (cytochrome P450, family 2, subfamily b, polypeptide 12) Rattus norvegicus
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Symbol: Cyp2b12
Name: cytochrome P450, family 2, subfamily b, polypeptide 12
Description: Exhibits arachidonic acid epoxygenase activity. Involved in epoxygenase P450 pathway. Localizes to the intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CYP2B6 (cytochrome P450 family 2 subfamily B member 6); PARTICIPATES IN cytochrome P450 monooxygenase mediated pathway of arachidonic acid metabolism; arachidonic acid metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH benzo[a]pyrene; copper atom; copper(0).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cyp2b15; CYPIIB12; cytochrome P-450b type b; cytochrome P450 2B12; cytochrome P450, 2b19; cytochrome P450, family 2, subfamily b, polypeptide 15
Orthologs:
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0183,511,167 - 83,522,965 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0184,763,724 - 84,775,524 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4181,780,088 - 81,791,887 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1181,858,198 - 81,931,360 (+)NCBI
Celera176,437,032 - 76,444,656 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp2b12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620088
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.