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Gene: Ugt1a8 (UDP glucuronosyltransferase family 1 member A8) Rattus norvegicus
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Symbol: Ugt1a8
Name: UDP glucuronosyltransferase family 1 member A8
Description: Exhibits glucuronosyltransferase activity. Involved in cellular response to organic cyclic compound and coumarin catabolic process. Localizes to the membrane. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic cancer. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; mycophenolic acid pharmacokinetics pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthol; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A3; UDP glycosyltransferase 1 family, polypeptide A8; UDP-glucuronosyltransferase 1-8; UDP-glucuronosyltransferase 1A8; UDPGT; UDPGT 1-8; Ugt1; UGT1*8; UGT1-08; UGT1.8; Ugt1a9
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0995,221,474 - 95,302,822 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl995,161,157 - 95,302,822 (+)Ensembl
Rnor_5.0994,910,377 - 94,990,037 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4987,017,029 - 87,098,362 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1987,202,433 - 87,284,226 (+)NCBI
Celera986,288,443 - 86,369,556 (+)NCBICelera
Cytogenetic Map9q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ugt1a8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708474
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.