 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
 |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
Save List to My RGD
| Create Name: | |
| Description: |
|
| Save what matters to you |
| {{ loginError }} |
| Sign in with your RGD account |
| Create New Account | Recover Password |
{{ watchLinkText }}
Select categories you would like to watch. Updates to this gene will be send to {{ username }}
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Cellular Component
Molecular Function
Gene-Chemical Interaction Annotations
|
|
|
Gene Ontology AnnotationsBiological Process
|
|
Cellular Component
|
|
Molecular Function
|
|
References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | Matsuo H, etal., Neurosci Lett 2004 Mar 25;358(2):123-6. |
| 4. | MGD data from the GO Consortium |
| 5. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 6. | RGD automated data pipeline |
| 7. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Slc7a10 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SLC7A10 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Slc7a10 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Slc7a10 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SLC7A10 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SLC7A10 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Slc7a10 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SLC7A10 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SLC7A10 (Chlorocebus sabaeus - African green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Slc7a10 (Heterocephalus glaber - naked mole-rat) |
No map positions available. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Position Markers| D7Bwg0847e |
|
|||||||||||||||||||||||||||||||||||
| RH131383 |
|
|||||||||||||||||||||||||||||||||||
| RH132091 |
|
QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
||||||||
Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 52 | 18 | 11 | ||||||||||
| Low | 3 | 22 | 38 | 27 | 5 | 27 | 6 | 7 | 22 | 27 | 14 | 6 | |
| Below cutoff | 18 | 11 | 6 | 14 | 6 | 2 | 4 | 8 | 9 | 2 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_053726 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017588653 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017588654 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AAHX01004672 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AB126813 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC109741 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC127467 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473979 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000015205 ⟹ ENSRNOP00000015205 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
|
| RefSeq Acc Id: | NM_053726 ⟹ NP_446178 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
|
||||||||||||||||||||
| Sequence: |
CCGACGGAGGACTGGCGGCGGGCCGGATAGACGGGGTAGCGCAGAGAGCTGGGATGAGGCGGGAhide sequence |
| RefSeq Acc Id: | XM_017588653 ⟹ XP_017444142 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
|
||||||||
| Sequence: |
CCCGTGCCAGCGCATGCGCCCGCCTGTGGGCGCTGTCCCGGGCTGCGAGGGCCGCGAGCGCACChide sequence |
| RefSeq Acc Id: | XM_017588654 ⟹ XP_017444143 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
|
||||||||
| Sequence: |
CCCGTGCCAGCGCATGCGCCCGCCTGTGGGCGCTGTCCCGGGCTGCGAGGGCCGCGAGCGCACChide sequence |
Protein Sequences| Protein RefSeqs | NP_446178 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017444142 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017444143 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAI27468 | (Get FASTA) | NCBI Sequence Viewer |
| BAD17967 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM07629 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM07630 | (Get FASTA) | NCBI Sequence Viewer | |
| P63116 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_446178 ⟸ NM_053726 |
| - UniProtKB: | Q75T81 (UniProtKB/TrEMBL) |
| - Sequence: |
MRRDSDMTGHIQQPGGRGNPSPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIhide sequence |
| RefSeq Acc Id: | XP_017444142 ⟸ XM_017588653 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MRRDSDMTGHIQQPGGRGNPSPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIhide sequence |
| RefSeq Acc Id: | XP_017444143 ⟸ XM_017588654 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MRRDSDMTGHIQQPGGRGNPSPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIhide sequence |
| RefSeq Acc Id: | ENSRNOP00000015205 ⟸ ENSRNOT00000015205 |
TranscriptomePromoters| RGD ID: | 13689965 | ||||||||
| Promoter ID: | EPDNEW_R489 | ||||||||
| Type: | single initiation site | ||||||||
| Name: | Slc7a10_1 | ||||||||
| Description: | solute carrier family 7 member 10 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
|
Strain Variation
Strain Sequence Variants (Rnor 6.0)
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
Damaging VariantsAssembly: Rnor_5.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 92575490 | 92575491 | G | A | snv | SHR/NCrlPrin (KNAW), SHR/NHsd (KNAW), SHR/OlaIpcv (KNAW), SHR/OlaIpcvPrin (KNAW), SHRSP/Gcrc (KNAW), IS-Tlk/Kyo (KyushuU), WKY/N (KNAW), WKY/NCrl (KNAW), WKY/NHsd (KNAW), IS/Kyo (KyushuU), WKY/Gcrc (KNAW) |
Assembly: Rnor_6.0
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 91444792 | 91444793 | G | A | snv | SHR/NHsd (RGD), WKY/Gcrc (RGD), WKY/N (MCW), WKY/NHsd (RGD), SHRSP/Gcrc (RGD) |
| 1 | 91447178 | 91447179 | A | T | snv | ACI/N (MCW) |
| 1 | 91447179 | 91447180 | T | A | snv | F344/NRrrc (MCW) |
Assembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 1 | 87707821 | 87707822 | G | A | snv | SHR/OlaIpcv (ICL), LCR/2Mco (UMich), SHRSP/Gcrc (MDC), HCR/2Mco (UMich), WKY/N (KNAW), SHR/OlaIpcv (KNAW), SHR/OlaIpcv (ICL), SHR/NHsd (ICL), SHRSP/Gcrc (ICL), WKY/Gcrc (ICL), WKY/NHsd (ICL), WKY/NCrl (ICL), HCR/1Mco (UMich), LCR/1Mco (UMich) |
| 1 | 87710207 | 87710208 | A | T | snv | ACI/N (KNAW) |
| 1 | 87710208 | 87710209 | T | A | snv | F344/NRrrc (KNAW) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:621672 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000010938 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000015205 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000015205 | ENTREZGENE, UniProtKB/TrEMBL |
| IMAGE_CLONE | IMAGE:7313174 | IMAGE-MGC_LOAD |
| InterPro | AA/rel_permease1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| KEGG Report | rno:114518 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:156544 | IMAGE-MGC_LOAD |
| NCBI Gene | 114518 | ENTREZGENE |
| Pfam | AA_permease_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PhenoGen | Slc7a10 | PhenoGen |
| UniGene | Rn.128083 | ENTREZGENE |
| UniProt | AAA1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
| Q75T81 | ENTREZGENE, UniProtKB/TrEMBL | |
| UniProt Secondary | Q9CW25 | UniProtKB/Swiss-Prot |
| Q9JMH8 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2016-02-24 | Slc7a10 | solute carrier family 7 member 10 | Slc7a10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2011-08-01 | Slc7a10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 | Slc7a10 | solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-10-23 | Slc7a10 | solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 | Slc7a10 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 10 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-01-20 | Slc7a10 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 10 | solute carrier family 7, (cationic amino acid transporter, y+ system) member 10 | Name updated | 1299863 | APPROVED | |
| 2002-08-07 | Slc7a10 | solute carrier family 7, (cationic amino acid transporter, y+ system) member 10 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
 |
| More on Slc7a10 | |
|
Alliance Gene |
|
NCBI Gene |
|
Ensembl Gene |
|
|
JBrowse: rn5 rn6 |
|
NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 621672 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
