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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1320284 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ADAMTS15 mRNA | CTD | PMID:22079256 | (-)-epigallocatechin 3-gallate | increases expression | ISO | RGD:1320284 | 6480464 | epigallocatechin gallate results in increased expression of ADAMTS15 mRNA | CTD | PMID:22079256 | 1,1-dichloroethene | decreases expression | ISO | RGD:1320285 | 6480464 | vinylidene chloride results in decreased expression of ADAMTS15 mRNA | CTD | PMID:26682919 | 1-chloro-2,4-dinitrobenzene | increases expression | ISO | RGD:1320285 | 6480464 | Dinitrochlorobenzene results in increased expression of ADAMTS15 mRNA | CTD | PMID:19647056 | 17beta-estradiol | increases expression | ISO | RGD:1320284 | 6480464 | Estradiol results in increased expression of ADAMTS15 mRNA | CTD | PMID:19484750 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ADAMTS15 mRNA | CTD | PMID:32741896 | 17beta-estradiol | increases expression | ISO | RGD:1320285 | 6480464 | Estradiol results in increased expression of ADAMTS15 mRNA | CTD | PMID:19484750 | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ADAMTS15 mRNA | CTD | PMID:32741896 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1320285 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ADAMTS15 mRNA | CTD | PMID:26377647 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADAMTS15 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1320285 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ADAMTS15 mRNA | CTD | PMID:29673856 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | RGD:1320284 | 6480464 | 2 more ... | CTD | PMID:26705709 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1320285 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of ADAMTS15 mRNA | CTD | PMID:30951980 | 4-(ethoxymethylene)-2-phenyloxazol-5-one | increases expression | ISO | RGD:1320285 | 6480464 | Oxazolone results in increased expression of ADAMTS15 mRNA | CTD | PMID:19647056 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ADAMTS15 mRNA | CTD | PMID:24780913 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of ADAMTS15 mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | RGD:1320284 | 6480464 | Aflatoxin B1 results in decreased methylation of ADAMTS15 intron | CTD | PMID:30157460 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ADAMTS15 mRNA | CTD | PMID:33354967 | arsane | affects methylation | ISO | RGD:1320284 | 6480464 | Arsenic affects the methylation of ADAMTS15 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1320284 | 6480464 | Arsenic affects the methylation of ADAMTS15 gene | CTD | PMID:25304211 | arsenous acid | decreases expression | ISO | RGD:1320284 | 6480464 | Arsenic Trioxide results in decreased expression of ADAMTS15 mRNA | CTD | PMID:26705709 | belinostat | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA | CTD | PMID:27188386 | benzo[a]pyrene | affects methylation | ISO | RGD:1320284 | 6480464 | Benzo(a)pyrene affects the methylation of ADAMTS15 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | decreases expression | ISO | RGD:1320285 | 6480464 | benzo(b)fluoranthene results in decreased expression of ADAMTS15 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ADAMTS15 mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases expression | ISO | RGD:1320285 | 6480464 | bisphenol A results in increased expression of ADAMTS15 mRNA | CTD | PMID:30951980 | bisphenol A | increases expression | ISO | RGD:1320284 | 6480464 | bisphenol A results in increased expression of ADAMTS15 mRNA | CTD | PMID:27685785 | bisphenol F | increases expression | ISO | RGD:1320285 | 6480464 | bisphenol F results in increased expression of ADAMTS15 mRNA | CTD | PMID:30951980 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of ADAMTS15 mRNA | CTD | PMID:32479839 | carbon nanotube | increases expression | ISO | RGD:1320285 | 6480464 | Nanotubes, Carbon results in increased expression of ADAMTS15 mRNA | CTD | PMID:25620056 | chloroprene | increases expression | ISO | RGD:1320285 | 6480464 | Chloroprene results in increased expression of ADAMTS15 mRNA | CTD | PMID:23125180 | choline | multiple interactions | ISO | RGD:1320285 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADAMTS15 gene more ... | CTD | PMID:20938992 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of ADAMTS15 mRNA | CTD | PMID:22023808 | cisplatin | decreases expression | ISO | RGD:1320284 | 6480464 | Cisplatin results in decreased expression of ADAMTS15 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | EXP | | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of ADAMTS15 mRNA | CTD | PMID:26033743 | copper atom | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of ADAMTS15 mRNA | CTD | PMID:26033743 | copper(0) | increases expression | EXP | | 6480464 | Copper deficiency results in increased expression of ADAMTS15 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | EXP | | 6480464 | [Copper co-treated with Dietary Sucrose] results in increased expression of ADAMTS15 mRNA | CTD | PMID:26033743 | diarsenic trioxide | decreases expression | ISO | RGD:1320284 | 6480464 | Arsenic Trioxide results in decreased expression of ADAMTS15 mRNA | CTD | PMID:26705709 | dichloroacetic acid | increases expression | ISO | RGD:1320285 | 6480464 | Dichloroacetic Acid results in increased expression of ADAMTS15 mRNA | CTD | PMID:28962523 | dioxygen | increases expression | ISO | RGD:1320284 | 6480464 | Oxygen deficiency results in increased expression of ADAMTS15 mRNA | CTD | PMID:26516004 | dorsomorphin | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | RGD:1320285 | 6480464 | Doxorubicin results in increased expression of ADAMTS15 mRNA | CTD | PMID:25896364 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of ADAMTS15 mRNA | CTD | PMID:29391264 | ethanol | multiple interactions | ISO | RGD:1320285 | 6480464 | [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of ADAMTS15 mRNA | CTD | PMID:30517762 | folic acid | multiple interactions | ISO | RGD:1320285 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADAMTS15 gene more ... | CTD | PMID:20938992 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of ADAMTS15 mRNA | CTD | PMID:27387713 | GW 4064 | increases expression | ISO | RGD:1320285 | 6480464 | GW 4064 results in increased expression of ADAMTS15 mRNA | CTD | PMID:26655953 | Indeno[1,2,3-cd]pyrene | decreases expression | ISO | RGD:1320285 | 6480464 | indeno(1 more ... | CTD | PMID:26377693 | L-methionine | multiple interactions | ISO | RGD:1320285 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ADAMTS15 gene more ... | CTD | PMID:20938992 | lead diacetate | decreases expression | ISO | RGD:1320285 | 6480464 | lead acetate results in decreased expression of ADAMTS15 mRNA | CTD | PMID:22613225 | naphthalene | decreases expression | EXP | | 6480464 | naphthalene analog results in decreased expression of ADAMTS15 mRNA | CTD | PMID:24976557 | nitrofen | decreases expression | EXP | | 6480464 | nitrofen results in decreased expression of ADAMTS15 mRNA | CTD | PMID:33484710 | panobinostat | increases expression | ISO | RGD:1320284 | 6480464 | panobinostat results in increased expression of ADAMTS15 mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA | CTD | PMID:27188386 | paracetamol | affects expression | ISO | RGD:1320285 | 6480464 | Acetaminophen affects the expression of ADAMTS15 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ADAMTS15 mRNA | CTD | PMID:33387578 | phenylmercury acetate | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | RGD:1320285 | 6480464 | pirinixic acid results in increased expression of ADAMTS15 mRNA | CTD | PMID:18301758 more ... | potassium chromate | multiple interactions | ISO | RGD:1320284 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ADAMTS15 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | RGD:1320284 | 6480464 | potassium chromate(VI) results in decreased expression of ADAMTS15 mRNA | CTD | PMID:22079256 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | RGD:1320285 | 6480464 | Pregnenolone Carbonitrile results in increased expression of ADAMTS15 mRNA | CTD | PMID:28903501 | S-(1,2-dichlorovinyl)-L-cysteine | decreases expression | ISO | RGD:1320284 | 6480464 | S-(1, 2-dichlorovinyl)cysteine results in decreased expression of ADAMTS15 mRNA | CTD | PMID:33725128 | SB 431542 | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | RGD:1320284 | 6480464 | sodium arsenite results in increased expression of ADAMTS15 mRNA | CTD | PMID:34032870 | sulforaphane | multiple interactions | ISO | RGD:1320285 | 6480464 | [NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAMTS15 mRNA | CTD | PMID:30529165 | sulforaphane | decreases expression | ISO | RGD:1320284 | 6480464 | sulforaphane results in decreased expression of ADAMTS15 mRNA | CTD | PMID:31838189 | sunitinib | increases expression | ISO | RGD:1320284 | 6480464 | Sunitinib results in increased expression of ADAMTS15 mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ADAMTS15 mRNA | CTD | PMID:32741896 | tetrachloromethane | multiple interactions | ISO | RGD:1320285 | 6480464 | [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of ADAMTS15 mRNA | CTD | PMID:30517762 | toluene 2,4-diisocyanate | increases expression | ISO | RGD:1320285 | 6480464 | Toluene 2, 4-Diisocyanate results in increased expression of ADAMTS15 mRNA | CTD | PMID:19647056 | trichostatin A | increases expression | ISO | RGD:1320284 | 6480464 | trichostatin A results in increased expression of ADAMTS15 mRNA | CTD | PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:1320284 | 6480464 | Valproic Acid results in increased expression of ADAMTS15 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA | CTD | PMID:27188386 | vorinostat | increases expression | ISO | RGD:1320284 | 6480464 | vorinostat results in increased expression of ADAMTS15 mRNA | CTD | PMID:26272509 | vorinostat | multiple interactions | ISO | RGD:1320284 | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADAMTS15 mRNA | CTD | PMID:27188386 | |