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Gene: Calhm5 (calcium homeostasis modulator family member 5) Rattus norvegicus

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Symbol:

Calhm5

Name:

calcium homeostasis modulator family member 5

RGD ID:

1310405

Description:

Predicted to enable monoatomic cation channel activity. Predicted to be involved in ATP export and monoatomic cation transmembrane transport. Predicted to be active in plasma membrane. Orthologous to human CALHM5 (calcium homeostasis modulator family member 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

calcium homeostasis modulator protein 5; Fam26e; family with sequence similarity 26, member E; hypothetical protein LOC294431; LOC294431; RGD1310405; similar to chromosome 6 open reading frame 188

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	26,609,400 - 26,615,478 (-)	NCBI		GRCr8
mRatBN7.2	20	26,066,270 - 26,072,348 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	26,066,242 - 26,072,272 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	27,068,471 - 27,074,549 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	26,454,816 - 26,460,894 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	27,203,055 - 27,209,133 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	27,651,817 - 27,673,817 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	27,651,312 - 27,657,983 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	29,476,316 - 29,497,695 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	37,693,422 - 37,699,449 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	37,716,432 - 37,722,467 (+)	NCBI
Celera	20	27,519,947 - 27,526,025 (-)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

body dysmorphic disorder (ISO)

congenital disorder of glycosylation Iaa (ISO)

intellectual disability (ISO)

microcephaly (ISO)

Tremor (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-bromohexadecanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

chloroprene (ISO)

chromium(6+) (ISO)

dexamethasone (ISO)

dichloroacetic acid (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethylparaben (ISO)

formaldehyde (ISO)

furan (EXP)

gentamycin (EXP)

indometacin (ISO)

lipopolysaccharide (ISO)

paracetamol (EXP)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

pioglitazone (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sevoflurane (ISO)

triclosan (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ATP export (IEA)

monoatomic cation transmembrane transport (IEA)

Cellular Component

plasma membrane (IBA)

Molecular Function

monoatomic cation channel activity (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:23376485

Genomics

Comparative Map Data

Calhm5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	26,609,400 - 26,615,478 (-)	NCBI		GRCr8
mRatBN7.2	20	26,066,270 - 26,072,348 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	26,066,242 - 26,072,272 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	27,068,471 - 27,074,549 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	26,454,816 - 26,460,894 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	27,203,055 - 27,209,133 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	27,651,817 - 27,673,817 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	27,651,312 - 27,657,983 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	29,476,316 - 29,497,695 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	37,693,422 - 37,699,449 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	37,716,432 - 37,722,467 (+)	NCBI
Celera	20	27,519,947 - 27,526,025 (-)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

CALHM5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	116,511,639 - 116,524,788 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	116,511,639 - 116,524,788 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	116,832,802 - 116,845,951 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	116,939,501 - 116,946,402 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	116,939,500 - 116,944,630	NCBI
Celera	6	117,575,879 - 117,582,776 (+)	NCBI		Celera
Cytogenetic Map	6	q22.1	NCBI
HuRef	6	114,412,412 - 114,419,285 (+)	NCBI		HuRef
CHM1_1	6	117,096,424 - 117,103,339 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	117,695,374 - 117,708,525 (+)	NCBI		T2T-CHM13v2.0

Calhm5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	33,967,348 - 33,972,515 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	33,963,811 - 33,972,515 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	34,091,352 - 34,096,519 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	34,087,815 - 34,096,519 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	33,811,158 - 33,816,325 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	33,780,768 - 33,785,935 (-)	NCBI		MGSCv36	mm8
Celera	10	35,001,152 - 35,006,319 (-)	NCBI		Celera
Cytogenetic Map	10	B1	NCBI
cM Map	10	18.85	NCBI

Calhm5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955526	203,971 - 213,328 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955526	203,971 - 213,328 (-)	NCBI	ChiLan1.0	ChiLan1.0

CALHM5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	136,525,202 - 136,531,031 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	134,418,155 - 134,424,692 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	114,319,599 - 114,325,898 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	118,464,517 - 118,471,411 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	118,464,517 - 118,471,411 (+)	Ensembl	panpan1.1		panPan2

CALHM5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	56,928,836 - 56,934,196 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	56,928,864 - 56,933,455 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	57,723,791 - 57,729,997 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	57,110,486 - 57,116,699 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	57,110,685 - 57,115,282 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	57,004,939 - 57,011,144 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	56,853,134 - 56,859,286 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	57,482,079 - 57,488,240 (+)	NCBI		UU_Cfam_GSD_1.0

Calhm5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	107,331,091 - 107,336,385 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936824	1,056,098 - 1,062,157 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936824	1,056,082 - 1,061,368 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CALHM5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	82,108,977 - 82,119,476 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	82,109,042 - 82,119,480 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	92,219,733 - 92,220,970 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CALHM5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	57,294,969 - 57,300,539 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	57,294,951 - 57,300,068 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	29,622,343 - 29,630,429 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Calhm5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624856	1,931,511 - 1,935,794 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624856	1,929,416 - 1,936,196 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Calhm5
5 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	428
Count of miRNA genes:	239
Interacting mature miRNAs:	284
Transcripts:	ENSRNOT00000057313
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	17617832	47606836	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	25106722	54435887	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8042410	29322208	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29191651	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29191651	Rat
2317880	Alcrsp25	Alcohol response QTL 25	2.3		response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	17697550	54435887	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578807	Rat
9590092	Insglur9	Insulin/glucose ratio QTL 9	18.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	20	11757515	54435887	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1530655	46530655	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	2892597	26381954	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26123605	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600972	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1527842	46527842	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29191651	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	19190721	54435887	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29191651	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29191651	Rat
7411652	Foco24	Food consumption QTL 24		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	11757515	54435887	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	25209734	54435887	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	2606836	47606836	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	25106722	54435887	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27339237	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600972	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	25106722	54435887	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	37	109	48	47	16	25	16	6	162	85	89	44	56	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089225	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057313 ⟹ ENSRNOP00000054130

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	20	26,066,242 - 26,072,272 (-)	Ensembl
Rnor_6.0 Ensembl	20	27,651,312 - 27,657,983 (-)	Ensembl

RefSeq Acc Id:

NM_001024977 ⟹ NP_001020148

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	26,609,400 - 26,615,478 (-)	NCBI
mRatBN7.2	20	26,066,270 - 26,072,348 (-)	NCBI
Rnor_6.0	20	27,651,817 - 27,657,895 (-)	NCBI
Rnor_5.0	20	29,476,316 - 29,497,695 (-)	NCBI
RGSC_v3.4	20	37,693,422 - 37,699,449 (+)	RGD
Celera	20	27,519,947 - 27,526,025 (-)	RGD

Sequence:

show sequence

CAGAGGAGGACTGTTCTTTCAAAAGAGCTCCACCCTCAGCCACAGCCATAGTTGCTGTGTTAAA
ACCAAGGCAAACGTCTTTTCCTCTTCGTGTGTGTGTGTCCGACATGGATGCTTTTCAGAGCATT
TTAAAATTCTTTCTTAACCAAAAAACTGCTATTGGTTACAGCTTCATGGCTTTGCTCACCGTGG
GAAGTGAACGTCTCTTCTCCCTAGTGGCATTTAAGTGCCCCTGCAGCATTGAGAACACTGCATA
TGGACTGGTTTTCCTCTTTGCCCCTGCCTGGGTGTTACTGATCCTTGGATTCTTTCTGAATAAC
AAGGCCTGGAGGCTCTTCACTGGTTGCTGTATGAACCCCCAAAAAATATTTCCTAGGAGACGCT
GCTGCCGCTTCTTCTACGTCCTGGGCCACATCACACTGAGTTCACTGGTGGCTCCGGTGATGTG
GCTCTCTGTGGCTTTGCTTAATGGGACGTTTTATGAATGTGCTATGAGTGGAACAAGAAGTACA
AGACTCCTGGAGATGATTTGCAAGGGGAAGCCCAAAGAGTGCTGGGAAGAACTGCACAAAGTCT
CTTGCGGTAAAAGTAGCATGGCAGCCATGGACAGTGAAGAGGTGAGGCTGTCTCTGCAGGCCCA
GTCTCAGATTCTAGGATGGTGCCTGATTTGTTCAGCATCCTTCTTCTCCCTGCTGACCACTTGT
TATGCACGCTGCAGATCTAAAGTCAGCTATCTGCAGCTGAGTTTTTGGAAGACATATGCACAAA
GGGAGAAGGAGCAATTGGAAAACAAACTCCTGGAATATGCCAACAAGCTGAGCGAGAGGAACCT
CAAATGCTTTTTTGAAAACAAGAAGCCAGATCCTTTTCCCATGCCCTCTTTTGCTGCCTGGGAG
GCTGCATCCGAGCTACACTCCTTCCACCAAGACCGTGAGCACTATAGCACCCTCCACAAGGTGG
TAGATGATGGTCTGGAACAAACTCCCCAAGAGGAAGAGACGACAATGATCCTTGTGGGTACCGC
CCAGAGTTTATGAATCATCCACCATCCCTGGCTCAGATATCCAGTGGTACACTCATTCTGAGTT
GAATCTTCTGCTGTTTCCATGACAACCTGAGTCTCTGCATTTTCTTACCATTAGAGCTTCTTTA
GACGATAATAACACAGTTGGAAACTGTTCTGAAACCTCCAAGAGCAATGTCTGGATGTGCTCAG
ACTGATGCTGAGTGATGACTGACTCAGGGTTGTGCCCAGGAGGTCCAACAGTTGGTCCAAGTTC
TAAGATTTTATGACTCAGCCCTCAAAGTTTGGCATGGTGGTCTGCCACTGTTTGCAAGCATTCG
GGGAGAGGTCTGTGCACAGTGGTATCCACACTGTGGCCATCAGGATCCCTTTCAGAAATATATC
CAACACCTTTTAAGTTGGAAGGAATTCTGCCATTTAATTAACATTCCTTTCTATAGAATACCTC
CATTCCCAAGGCTTAGTAAACTGAAAGAATATAATGTCTAAACATCAGAGGTTCCTGCATTTTC
CCCAATTTCTGAAAGTCTGCCTGGGGACAGGGCTGCCTCATGACTGCTGTGGGTGGTAGGCGCT
TAAACCTTCACAGGACAATTTCTACATTCAAAAGACAACCACATAAGGCTTACATACAAGACTG
TATTGATATAAAGACAAATACATTAATATTGTAAAAAAAAAAAAAAAAAAAAAAAAAGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001020148	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89225	(Get FASTA)	NCBI Sequence Viewer
	EDL93097	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054130.2
	ENSRNOP00065034603
GenBank Protein	Q5FWS4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020148 ⟸ NM_001024977

- UniProtKB:

Q5FWS4 (UniProtKB/Swiss-Prot), A6K3S5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDAFQSILKFFLNQKTAIGYSFMALLTVGSERLFSLVAFKCPCSIENTAYGLVFLFAPAWVLLI
LGFFLNNKAWRLFTGCCMNPQKIFPRRRCCRFFYVLGHITLSSLVAPVMWLSVALLNGTFYECA
MSGTRSTRLLEMICKGKPKECWEELHKVSCGKSSMAAMDSEEVRLSLQAQSQILGWCLICSASF
FSLLTTCYARCRSKVSYLQLSFWKTYAQREKEQLENKLLEYANKLSERNLKCFFENKKPDPFPM
PSFAAWEAASELHSFHQDREHYSTLHKVVDDGLEQTPQEEETTMILVGTAQSL

hide sequence

Ensembl Acc Id:

ENSRNOP00000054130 ⟸ ENSRNOT00000057313

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FWS4-F1-model_v2	AlphaFold	Q5FWS4	1-309	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701576

Promoter ID:

EPDNEW_R12099

Type:

initiation region

Name:

Calhm5_1

Description:

calcium homeostasis modulator family member 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	27,657,819 - 27,657,879	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310405	AgrOrtholog
BioCyc Gene	G2FUF-3793	BioCyc
Ensembl Genes	ENSRNOG00000000825	Ensembl, UniProtKB/Swiss-Prot
	ENSRNOG00065024639	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000057313.5	UniProtKB/Swiss-Prot
	ENSRNOT00065042302	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7309006	IMAGE-MGC_LOAD
InterPro	CALHM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:294431	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:105561	IMAGE-MGC_LOAD
NCBI Gene	294431	ENTREZGENE
PANTHER	CALCIUM HOMEOSTASIS MODULATOR PROTEIN	UniProtKB/TrEMBL
	CALCIUM HOMEOSTASIS MODULATOR PROTEIN 5	UniProtKB/TrEMBL
	PTHR32261	UniProtKB/Swiss-Prot
	PTHR32261:SF8	UniProtKB/Swiss-Prot
Pfam	Ca_hom_mod	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Calhm5	PhenoGen
RatGTEx	ENSRNOG00000000825	RatGTEx
	ENSRNOG00065024639	RatGTEx
UniProt	A6K3S5	ENTREZGENE, UniProtKB/TrEMBL
	CAHM5_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-07-31	Calhm5	calcium homeostasis modulator family member 5	Fam26e	family with sequence similarity 26, member E	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Fam26e	family with sequence similarity 26, member E	RGD1310405	similar to chromosome 6 open reading frame 188	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1310405	similar to chromosome 6 open reading frame 188	RGD1310405_predicted	similar to chromosome 6 open reading frame 188 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1310405_predicted	similar to chromosome 6 open reading frame 188 (predicted)	LOC294431_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC294431_predicted	similar to chromosome 6 open reading frame 188 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar