Lamtor3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3) - Rat Genome Database

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Gene: Lamtor3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3) Rattus norvegicus
Analyze
Symbol: Lamtor3
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
RGD ID: 1307133
Description: Predicted to enable kinase activator activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and protein localization. Predicted to act upstream of or within positive regulation of MAPK cascade and protein localization to cell junction. Predicted to be located in late endosome membrane. Predicted to be part of FNIP-folliculin RagC/D GAP and Ragulator complex. Predicted to be active in late endosome and lysosomal membrane. Orthologous to human LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 2,6-dinitrotoluene; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; LOC362045; Map2k1ip1; Mapksp1; MEK partner 1; MGC106009; mitogen-activated protein kinase kinase 1 interacting protein 1; mitogen-activated protein kinase kinase 1-interacting protein 1; mitogen-activated protein kinase scaffold protein 1; MP1; ragulator complex protein LAMTOR3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,084,795 - 229,097,028 (+)NCBIGRCr8
mRatBN7.22226,411,389 - 226,423,612 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,411,400 - 226,423,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,166,078 - 234,178,334 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,065,862 - 232,078,076 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02226,930,478 - 226,942,734 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,160,821 - 243,173,057 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,160,917 - 243,173,048 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02261,708,575 - 261,721,120 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,408,727 - 235,421,196 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,395,466 - 235,407,935 (+)NCBI
Celera2218,577,883 - 218,589,947 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Regulation of mTORC1 by amino acids. Bar-Peled L and Sabatini DM, Trends Cell Biol. 2014 Jul;24(7):400-6. doi: 10.1016/j.tcb.2014.03.003. Epub 2014 Mar 31.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes. Nada S, etal., EMBO J. 2009 Mar 4;28(5):477-89. doi: 10.1038/emboj.2008.308. Epub 2009 Jan 29.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15263099   PMID:15489334   PMID:15923628   PMID:19056867   PMID:20381137   PMID:21423176   PMID:22980980   PMID:23376485   PMID:24841562  


Genomics

Comparative Map Data
Lamtor3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,084,795 - 229,097,028 (+)NCBIGRCr8
mRatBN7.22226,411,389 - 226,423,612 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,411,400 - 226,423,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,166,078 - 234,178,334 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,065,862 - 232,078,076 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02226,930,478 - 226,942,734 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,160,821 - 243,173,057 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,160,917 - 243,173,048 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02261,708,575 - 261,721,120 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,408,727 - 235,421,196 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,395,466 - 235,407,935 (+)NCBI
Celera2218,577,883 - 218,589,947 (+)NCBICelera
Cytogenetic Map2q43NCBI
LAMTOR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,878,336 - 99,894,546 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,878,336 - 99,894,428 (-)EnsemblGRCh38hg38GRCh38
GRCh374100,799,493 - 100,815,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364101,021,387 - 101,034,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 344101,159,542 - 101,172,881NCBI
Celera498,096,915 - 98,113,123 (-)NCBICelera
Cytogenetic Map4q23NCBI
HuRef496,537,819 - 96,554,027 (-)NCBIHuRef
CHM1_14100,776,002 - 100,792,210 (-)NCBICHM1_1
T2T-CHM13v2.04103,193,819 - 103,210,029 (-)NCBIT2T-CHM13v2.0
Lamtor3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,624,316 - 137,634,523 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,624,267 - 137,634,661 (+)EnsemblGRCm39 Ensembl
GRCm383137,918,555 - 137,928,762 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3137,918,506 - 137,928,900 (+)EnsemblGRCm38mm10GRCm38
MGSCv373137,581,519 - 137,591,726 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363137,855,942 - 137,866,149 (+)NCBIMGSCv36mm8
Celera3144,329,273 - 144,339,499 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map363.97NCBI
Lamtor3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554967,788,997 - 7,809,143 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554967,789,210 - 7,809,143 (+)NCBIChiLan1.0ChiLan1.0
LAMTOR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,959,862 - 97,976,022 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1498,243,665 - 98,259,762 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0492,304,115 - 92,317,461 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,965,111 - 102,978,205 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,965,111 - 102,978,205 (-)Ensemblpanpan1.1panPan2
LAMTOR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13221,820,853 - 21,834,443 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3221,820,985 - 21,834,351 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3220,062,612 - 20,076,488 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03222,041,383 - 22,055,265 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3222,041,383 - 22,055,230 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13222,017,859 - 22,031,725 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03221,805,029 - 21,818,875 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03218,049,308 - 18,063,178 (+)NCBIUU_Cfam_GSD_1.0
Lamtor3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530119,769,726 - 19,784,773 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365203,113,235 - 3,128,333 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365203,113,178 - 3,128,333 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMTOR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8120,623,550 - 120,643,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18120,625,897 - 120,642,630 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28129,805,161 - 129,821,876 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LAMTOR3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1748,009,857 - 48,025,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603726,481,519 - 26,497,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lamtor3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248307,296,458 - 7,312,186 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248307,296,133 - 7,311,907 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lamtor3
74 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:67
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000014027
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat

Markers in Region
RH127334  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22226,423,312 - 226,423,516 (+)MAPPERmRatBN7.2
Rnor_6.02243,172,761 - 243,172,964NCBIRnor6.0
Rnor_5.02261,720,826 - 261,721,029UniSTSRnor5.0
RGSC_v3.42235,420,902 - 235,421,105UniSTSRGSC3.4
Celera2218,589,653 - 218,589,856UniSTS
Cytogenetic Map2q44UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 56 40 19 40 8 11 74 35 40 11 8
Low 1 1 1 1
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000014027   ⟹   ENSRNOP00000014027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2226,411,400 - 226,423,607 (+)Ensembl
Rnor_6.0 Ensembl2243,160,917 - 243,173,048 (+)Ensembl
RefSeq Acc Id: NM_001008375   ⟹   NP_001008376
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,084,890 - 229,097,028 (+)NCBI
mRatBN7.22226,411,468 - 226,423,607 (+)NCBI
Rnor_6.02243,160,917 - 243,173,055 (+)NCBI
Rnor_5.02261,708,575 - 261,721,120 (+)NCBI
RGSC_v3.42235,408,727 - 235,421,196 (+)RGD
Celera2218,577,883 - 218,589,947 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233383   ⟹   XP_006233445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,084,797 - 229,097,028 (+)NCBI
mRatBN7.22226,411,392 - 226,423,612 (+)NCBI
Rnor_6.02243,160,821 - 243,173,057 (+)NCBI
Rnor_5.02261,708,575 - 261,721,120 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233385   ⟹   XP_006233447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,084,797 - 229,097,028 (+)NCBI
mRatBN7.22226,411,389 - 226,423,612 (+)NCBI
Rnor_6.02243,160,821 - 243,173,057 (+)NCBI
Rnor_5.02261,708,575 - 261,721,120 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063282222   ⟹   XP_063138292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,084,800 - 229,097,028 (+)NCBI
RefSeq Acc Id: XM_063282224   ⟹   XP_063138294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,084,799 - 229,097,028 (+)NCBI
RefSeq Acc Id: XM_063282225   ⟹   XP_063138295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,084,795 - 229,097,028 (+)NCBI
RefSeq Acc Id: NP_001008376   ⟸   NM_001008375
- UniProtKB: Q5U204 (UniProtKB/Swiss-Prot),   A6HW13 (UniProtKB/TrEMBL),   A0A8L2Q6U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233445   ⟸   XM_006233383
- Peptide Label: isoform X2
- UniProtKB: Q5U204 (UniProtKB/Swiss-Prot),   A6HW13 (UniProtKB/TrEMBL),   A0A8L2Q6U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233447   ⟸   XM_006233385
- Peptide Label: isoform X2
- UniProtKB: Q5U204 (UniProtKB/Swiss-Prot),   A6HW13 (UniProtKB/TrEMBL),   A0A8L2Q6U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014027   ⟸   ENSRNOT00000014027
RefSeq Acc Id: XP_063138295   ⟸   XM_063282225
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138294   ⟸   XM_063282224
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063138292   ⟸   XM_063282222
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U204-F1-model_v2 AlphaFold Q5U204 1-124 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691779
Promoter ID:EPDNEW_R2304
Type:initiation region
Name:Lamtor3_1
Description:late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02243,160,885 - 243,160,945EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307133 AgrOrtholog
BioCyc Gene G2FUF-51104 BioCyc
Ensembl Genes ENSRNOG00000010552 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055010783 UniProtKB/Swiss-Prot
  ENSRNOG00060023235 UniProtKB/Swiss-Prot
  ENSRNOG00065025946 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000014027.6 UniProtKB/TrEMBL
  ENSRNOT00055018215 UniProtKB/Swiss-Prot
  ENSRNOT00060040222 UniProtKB/Swiss-Prot
  ENSRNOT00065044736 UniProtKB/Swiss-Prot
Gene3D-CATH Dynein light chain 2a, cytoplasmic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7304027 IMAGE-MGC_LOAD
InterPro LAMTOR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362045 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:106009 IMAGE-MGC_LOAD
NCBI Gene 362045 ENTREZGENE
PANTHER PTHR13378 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAGULATOR COMPLEX PROTEIN LAMTOR3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MAPKK1_Int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lamtor3 PhenoGen
RatGTEx ENSRNOG00000010552 RatGTEx
  ENSRNOG00055010783 RatGTEx
  ENSRNOG00060023235 RatGTEx
  ENSRNOG00065025946 RatGTEx
SMART MAPKK1_Int UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Roadblock/LC7 domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2Q6U4 ENTREZGENE, UniProtKB/TrEMBL
  A6HW13 ENTREZGENE, UniProtKB/TrEMBL
  LTOR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Lamtor3  late endosomal/lysosomal adaptor, MAPK and MTOR activator 3  Map2k1ip1  mitogen-activated protein kinase kinase 1 interacting protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Map2k1ip1  mitogen-activated protein kinase kinase 1 interacting protein 1  Map2k1ip1_predicted  mitogen-activated protein kinase kinase 1 interacting protein 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Map2k1ip1_predicted  mitogen-activated protein kinase kinase 1 interacting protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED