Crb2 (crumbs cell polarity complex component 2) - Rat Genome Database

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Gene: Crb2 (crumbs cell polarity complex component 2) Rattus norvegicus
Analyze
Symbol: Crb2
Name: crumbs cell polarity complex component 2
RGD ID: 1309368
Description: Predicted to enable aspartic-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including embryonic morphogenesis; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and maintenance of epithelial cell apical/basal polarity. Predicted to be located in several cellular components, including apical plasma membrane; apicolateral plasma membrane; and cell junction. Predicted to be part of subapical complex. Predicted to be active in apical part of cell and plasma membrane. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 9 and ventriculomegaly - cystic kidney disease. Orthologous to human CRB2 (crumbs cell polarity complex component 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; furan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: crumbs 2, cell polarity complex component; crumbs family member 2; crumbs homolog 2; crumbs homolog 2 (Drosophila); LOC366031; RGD1309368; similar to 5930402A21 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8341,946,694 - 41,974,629 (+)NCBIGRCr8
mRatBN7.2321,542,138 - 21,564,876 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl321,542,221 - 21,563,294 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx325,010,380 - 25,030,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0333,595,339 - 33,615,663 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0331,407,370 - 31,427,643 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0322,037,812 - 22,061,247 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl322,038,357 - 22,058,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0327,273,846 - 27,296,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4317,539,288 - 17,559,629 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1317,436,230 - 17,456,001 (+)NCBI
Celera319,976,389 - 19,996,310 (+)NCBICelera
Cytogenetic Map3q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa. Alves CH, etal., Hum Mol Genet. 2014 Feb 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis. Pellissier LP, etal., PLoS Genet. 2013 Dec;9(12):e1003976. doi: 10.1371/journal.pgen.1003976. Epub 2013 Dec 5.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19056867   PMID:20299451   PMID:22072575   PMID:23376485   PMID:23533145   PMID:25636444   PMID:26496195   PMID:27870829  


Genomics

Comparative Map Data
Crb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8341,946,694 - 41,974,629 (+)NCBIGRCr8
mRatBN7.2321,542,138 - 21,564,876 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl321,542,221 - 21,563,294 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx325,010,380 - 25,030,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0333,595,339 - 33,615,663 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0331,407,370 - 31,427,643 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0322,037,812 - 22,061,247 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl322,038,357 - 22,058,871 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0327,273,846 - 27,296,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4317,539,288 - 17,559,629 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1317,436,230 - 17,456,001 (+)NCBI
Celera319,976,389 - 19,996,310 (+)NCBICelera
Cytogenetic Map3q11NCBI
CRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389123,354,065 - 123,380,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9123,356,170 - 123,380,324 (+)EnsemblGRCh38hg38GRCh38
GRCh379126,118,476 - 126,142,605 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369125,158,269 - 125,180,853 (+)NCBINCBI36Build 36hg18NCBI36
Build 349123,198,002 - 123,215,932NCBI
Celera996,766,676 - 96,789,262 (+)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef995,733,274 - 95,755,982 (+)NCBIHuRef
CHM1_19126,267,137 - 126,289,699 (+)NCBICHM1_1
T2T-CHM13v2.09135,551,766 - 135,578,059 (+)NCBIT2T-CHM13v2.0
Crb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39237,666,238 - 37,689,115 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl237,666,261 - 37,689,115 (+)EnsemblGRCm39 Ensembl
GRCm38237,776,225 - 37,799,103 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl237,776,249 - 37,799,103 (+)EnsemblGRCm38mm10GRCm38
MGSCv37237,631,769 - 37,654,623 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera237,461,524 - 37,484,418 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map224.19NCBI
Crb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554194,607,507 - 4,626,608 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554194,604,883 - 4,626,675 (-)NCBIChiLan1.0ChiLan1.0
CRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21115,966,284 - 16,003,414 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1915,968,928 - 16,005,767 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0994,473,423 - 94,511,285 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19123,011,887 - 123,034,544 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9123,011,968 - 123,032,855 (+)Ensemblpanpan1.1panPan2
CRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1959,427,661 - 59,450,436 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl959,427,569 - 59,450,434 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha958,621,652 - 58,645,938 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0960,346,151 - 60,370,373 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl960,346,149 - 60,370,391 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1959,104,766 - 59,129,041 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0959,420,335 - 59,444,621 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0959,512,745 - 59,536,914 (-)NCBIUU_Cfam_GSD_1.0
Crb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947192,024,531 - 192,047,256 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648711,793,005 - 11,812,934 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648711,793,078 - 11,813,803 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1264,276,987 - 264,301,713 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11264,277,549 - 264,301,731 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21297,886,591 - 297,910,766 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11214,756,897 - 14,782,131 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1214,758,618 - 14,779,514 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660791,290,401 - 1,312,970 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476011,579,163 - 11,598,287 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476011,576,683 - 11,598,354 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Crb2
91 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:65
Interacting mature miRNAs:69
Transcripts:ENSRNOT00000037257
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)31043430624512004Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145428441896Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 2 45 111 78 77 47 24 47 4 188 87 93 45 59 30

Sequence


Ensembl Acc Id: ENSRNOT00000037257   ⟹   ENSRNOP00000035420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl321,542,221 - 21,563,294 (+)Ensembl
Rnor_6.0 Ensembl322,038,357 - 22,058,871 (+)Ensembl
RefSeq Acc Id: NM_001135761   ⟹   NP_001129233
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,951,900 - 41,974,629 (+)NCBI
mRatBN7.2321,542,145 - 21,564,876 (+)NCBI
Rnor_6.0322,038,357 - 22,058,871 (+)NCBI
Rnor_5.0327,273,846 - 27,296,956 (+)NCBI
RGSC_v3.4317,539,288 - 17,559,629 (+)RGD
Celera319,976,389 - 19,996,310 (+)RGD
Sequence:
RefSeq Acc Id: XM_063284262   ⟹   XP_063140332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,946,694 - 41,974,629 (+)NCBI
RefSeq Acc Id: XM_063284263   ⟹   XP_063140333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8341,946,694 - 41,974,629 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001129233 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140332 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140333 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM00520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000035420.3
RefSeq Acc Id: NP_001129233   ⟸   NM_001135761
- Peptide Label: precursor
- UniProtKB: D4A3W2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035420   ⟸   ENSRNOT00000037257
RefSeq Acc Id: XP_063140332   ⟸   XM_063284262
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063140333   ⟸   XM_063284263
- Peptide Label: isoform X2
Protein Domains
EGF-like   Laminin G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3W2-F1-model_v2 AlphaFold D4A3W2 1-1283 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309368 AgrOrtholog
BioCyc Gene G2FUF-49921 BioCyc
Ensembl Genes ENSRNOG00000025498 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037257.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_subgrp UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_Ca-bd UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  Notch_Cell-Fate_Det UniProtKB/TrEMBL
KEGG Report rno:366031 UniProtKB/TrEMBL
NCBI Gene 366031 ENTREZGENE
PANTHER CRUMBS FAMILY MEMBER UniProtKB/TrEMBL
  PROTEIN CRUMBS HOMOLOG 2 UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
PhenoGen Crb2 PhenoGen
PRINTS EGFBLOOD UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025498 RatGTEx
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  EGF/Laminin UniProtKB/TrEMBL
UniProt D4A3W2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-04 Crb2  crumbs cell polarity complex component 2  Crb2  crumbs 2, cell polarity complex component  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-01 Crb2  crumbs 2, cell polarity complex component  Crb2  crumbs family member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-02-13 Crb2  crumbs family member 2  Crb2  crumbs homolog 2 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-01 Crb2  crumbs homolog 2 (Drosophila)  RGD1309368  similar to 5930402A21 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1309368  similar to 5930402A21 protein   RGD1309368_predicted  similar to 5930402A21 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1309368_predicted  similar to 5930402A21 protein (predicted)  LOC366031_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC366031_predicted  similar to 5930402A21 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL