Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: HECW1 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1) Homo sapiens
Analyze
Symbol: HECW1
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of sodium ion transmembrane transporter activity; and regulation of dendrite morphogenesis. Localizes to the cytosol; INTERACTS WITH 17beta-estradiol; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: E3 ubiquitin-protein ligase HECW1; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain-containing protein 1; HECT-type E3 ubiquitin transferase HECW1; hNEDL1; KIAA0322; NEDD4-like E3 ubiquitin-protein ligase 1; NEDD4-like ubiquitin-protein ligase 1; NEDL1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl743,112,629 - 43,566,001 (+)Ensembl
GRCh38743,112,580 - 43,566,001 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37743,152,198 - 43,603,213 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36743,118,723 - 43,569,463 (+)NCBINCBI36hg18NCBI36
Build 34743,124,601 - 43,376,178NCBI
Celera743,142,126 - 43,592,827 (+)NCBI
Cytogenetic Map7p14.1-p13NCBI
HuRef743,037,592 - 43,488,098 (+)NCBIHuRef
CHM1_1743,155,739 - 43,606,212 (+)NCBICHM1_1
CRA_TCAGchr7v2743,191,688 - 43,642,449 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on HECW1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352203
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.