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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:DDE
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Accession:CHEBI:16598 term browser browse the term
Definition:A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2.
Synonyms:exact_synonym: 1-chloro-4-[2,2-dichloro-1-(4-chlorophenyl)ethenyl]benzene
 related_synonym: 1,1'-(2,2-dichloroethene-1,1-diyl)bis(4-chlorobenzene);   1,1-bis-(4-chlorophenyl)-2,2-dichloroethene;   1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene;   2,2'-bis(4-chlorophenyl)-1,1-dichloroethylene;   4,4'-DDE;   Formula=C14H8Cl4;   InChI=1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H;   InChIKey=UCNVFOCBFJOQAL-UHFFFAOYSA-N;   SMILES=ClC(Cl)=C(C1=CC=C(Cl)C=C1)C1=CC=C(Cl)C=C1;   p,p'-(Dichlorodiphenyl)-2,2-dichloroethylene;   p,p'-DDE
 alt_id: CHEBI:11130;   CHEBI:18851;   CHEBI:195494;   CHEBI:474
 xref: CAS:72-55-9;   FooDB:FDB097419;   HMDB:HMDB0304759;   KEGG:C04596
 xref_mesh: MESH:D003633
 xref: MetaCyc:DICHLOROBIS-CPD;   PDBeChem:6WS;   PMCID:PMC7208238;   PMID:11513126;   PMID:15070871;   PMID:15710169;   PMID:20368122;   PMID:22142728;   PMID:23415487;   PMID:24328540;   PMID:28042045;   PMID:31792309;   PMID:32393266;   PMID:33287856;   PMID:33756427;   PMID:35623197;   PMID:37236336;   Reaxys:1913355;   UM-BBD_compID:c0406;   Wikipedia:Dichlorodiphenyldichloroethylene


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DDE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ABCB11 mRNA CTD PMID:28392238 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases expression		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ABCB1 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of ABCB1A mRNA
Dichlorodiphenyl Dichloroethylene results in decreased expression of ABCB1 mRNA		 CTD PMID:15710169 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ABCB1B mRNA CTD PMID:15710169 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ABCC2 mRNA CTD PMID:28392238 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ABCC8 mRNA CTD PMID:35457000 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity ISO Dichlorodiphenyl Dichloroethylene metabolite results in decreased activity of ABCG2 protein CTD PMID:23169446 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ABCG8 protein CTD PMID:27203212 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ACACA mRNA CTD PMID:25541407 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of ACADM protein CTD PMID:28397872 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of ACADS protein CTD PMID:28397872 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions EXP [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ACE2 mRNA CTD PMID:30415545 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ACOX1 mRNA CTD PMID:25541407 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Actn1 actinin, alpha 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ACTN1 mRNA CTD PMID:25607892 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Acvr1c activin A receptor type 1C multiple interactions ISO [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVR1C mRNA CTD PMID:19422813 NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Acvrl1 activin A receptor like type 1 multiple interactions ISO [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ACVRL1 mRNA CTD PMID:19422813 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
increases secretion
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ADIPOQ mRNA
Dichlorodiphenyl Dichloroethylene results in increased secretion of ADIPOQ protein
[Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ADIPOQ protein		 CTD PMID:21044676 PMID:25541407 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of ADM mRNA CTD PMID:15885261 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Agt angiotensinogen multiple interactions
increases expression		 EXP [Dichlorodiphenyl Dichloroethylene co-treated with Dietary Fats] results in increased expression of AGT mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of AGT mRNA		 CTD PMID:30415545 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions EXP [Dichlorodiphenyl Dichloroethylene co-treated with Dietary Fats] affects the expression of AGTR1B mRNA CTD PMID:30415545 NCBI chr 2:102,844,969...102,920,232
Ensembl chr 2:102,844,969...102,920,232 		JBrowse link
G Ahr aryl hydrocarbon receptor affects response to substance
increases expression
multiple interactions		 ISO AHR polymorphism affects the susceptibility to Dichlorodiphenyl Dichloroethylene
Dichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNA
TNF protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNA]
AHR protein affects the susceptibility to Dichlorodiphenyl Dichloroethylene
Dichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of AHR protein		 CTD PMID:25084496 PMID:25316167 PMID:32721735 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Alk ALK receptor tyrosine kinase multiple interactions ISO [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ALK mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA CTD PMID:19422813 PMID:28263720 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of AMPD3 mRNA CTD PMID:15885261 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of APAF1 mRNA CTD PMID:25410718 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apoe apolipoprotein E increases response to substance ISO APOE gene polymorphism results in increased susceptibility to Dichlorodiphenyl Dichloroethylene CTD PMID:24473795 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of APP protein CTD PMID:24473795 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Ar androgen receptor multiple interactions
affects binding
increases activity
increases expression		 ISO
EXP		 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein modified form]; [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] promotes the reaction [AR protein mutant form binds to KLK3 enhancer]; [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased expression of KLK3 mRNA; [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of MAPK1 protein; [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of MAPK3 protein; [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of VASP protein; Dichlorodiphenyl Dichloroethylene affects the reaction [CGA protein results in increased expression of AR mRNA]; Dichlorodiphenyl Dichloroethylene affects the reaction [Dihydrotestosterone results in increased activity of AR protein modified form]; Dichlorodiphenyl Dichloroethylene analog inhibits the reaction [Metribolone results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene binds to and results in decreased activity of AR protein; Dichlorodiphenyl Dichloroethylene binds to and results in increased activity of AR protein; Dichlorodiphenyl Dichloroethylene inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of AR mRNA]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dihydrotestosterone binds to AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone affects the localization of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased activity of AR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of AR protein]; Dihydrotestosterone inhibits the reaction [Dichlorodiphenyl Dichloroethylene analog results in increased activity of AR protein]
Dichlorodiphenyl Dichloroethylene binds to AR protein
Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein; Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form
Dichlorodiphenyl Dichloroethylene results in increased expression of AR mRNA
Dichlorodiphenyl Dichloroethylene binds to and results in decreased activity of AR protein; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Androgens binds to AR protein]		 CTD PMID:7791873 PMID:9073609 PMID:9705896 PMID:10053169 PMID:10448550 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arg1 arginase 1 multiple interactions ISO Dichlorodiphenyl Dichloroethylene promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of ARG1 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [IL4 protein results in increased expression of ARG1 mRNA] CTD PMID:26748080 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ARNT mRNA CTD PMID:32721735 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Arx aristaless related homeobox increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ARX mRNA CTD PMID:36674557 NCBI chr  X:58,016,233...58,028,149
Ensembl chr  X:58,016,233...58,028,142 		JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions EXP [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ASS1 mRNA CTD PMID:30415545 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atf3 activating transcription factor 3 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of ATF3 protein CTD PMID:27589886 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf6 activating transcription factor 6 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of ATF6 protein CTD PMID:27589886 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO ATG7 protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein] CTD PMID:32721735 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Avp arginine vasopressin multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of AVP mRNA CTD PMID:34383603 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BACE1 mRNA CTD PMID:25607892 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace2 beta-secretase 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of BACE2 mRNA CTD PMID:25607892 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BAK1 mRNA] CTD PMID:21281706 PMID:21384494 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in increased expression of BAX mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of BAX protein
Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BAX mRNA]		 CTD PMID:19545618 PMID:21281706 PMID:21384494 PMID:25410718 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of BCL2 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of BCL2 protein CTD PMID:19545618 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l11 Bcl2-like 11 affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of BCL2L11 mRNA CTD PMID:24576310 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of BCL2L2 mRNA CTD PMID:21384494 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of BDNF mRNA CTD PMID:25607892 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 multiple interactions
affects expression		 ISO BECN1 protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]
Dichlorodiphenyl Dichloroethylene affects the expression of BECN1 mRNA		 CTD PMID:32721735 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA CTD PMID:28263720 NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage ISO Dichlorodiphenyl Dichloroethylene results in increased cleavage of BID protein CTD PMID:19545618 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bik BCL2-interacting killer affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of BIK mRNA CTD PMID:24576310 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of BRCA1 mRNA
fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BRCA1 mRNA]		 CTD PMID:20206645 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of BSN mRNA CTD PMID:25607892 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of BTG2 protein CTD PMID:27589886 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1A mRNA CTD PMID:25607892 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1B mRNA CTD PMID:25607892 NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1C mRNA CTD PMID:25607892 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA CTD PMID:25607892 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1G mRNA CTD PMID:25607892 NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CACNA1I mRNA CTD PMID:25607892 NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of CACNA2D3 mRNA CTD PMID:25607892 NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351 		JBrowse link
G Cacnb1 calcium voltage-gated channel auxiliary subunit beta 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNB1 mRNA CTD PMID:25607892 NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNB3 mRNA CTD PMID:25607892 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CACNG2 mRNA CTD PMID:25607892 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CACNG6 mRNA CTD PMID:25607892 NCBI chr 1:65,732,910...65,747,377
Ensembl chr 1:65,732,632...65,747,341 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNG7 mRNA CTD PMID:25607892 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cadm1 cell adhesion molecule 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CADM1 mRNA CTD PMID:25607892 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Calb2 calbindin 2 multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of CALB2 mRNA] CTD PMID:28572628 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CAMK2B mRNA CTD PMID:25607892 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of CAMK2G mRNA CTD PMID:25607892 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050 		JBrowse link
G Capn1 calpain 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CAPN1 mRNA CTD PMID:21384494 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CA2 mRNA CTD PMID:15885261 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Card10 caspase recruitment domain family, member 10 affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of CARD10 mRNA CTD PMID:24576310 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224 		JBrowse link
G Card6 caspase recruitment domain family, member 6 affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of CARD6 mRNA CTD PMID:24576310 NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846 		JBrowse link
G Cartpt CART prepropeptide multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in increased expression of CARTPT mRNA CTD PMID:34383603 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp12 caspase 12 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CASP12 mRNA CTD PMID:21384494 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression
affects expression
multiple interactions		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein
Dichlorodiphenyl Dichloroethylene results in increased expression of CASP3 mRNA
Dichlorodiphenyl Dichloroethylene affects the expression of CASP3 protein
ATG7 protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]; BECN1 protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]; diazepinylbenzoic acid inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]; ethyl (5-(diethylglycyl)-10,11-dihydro-5H-dibenzo(b,f)azepin-3-yl)carbamate inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]; RXRA mRNA promotes the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]; RXRB mRNA promotes the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]		 CTD PMID:19545618 PMID:19644561 PMID:20025943 PMID:21384494 PMID:24576310 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CASP4 mRNA CTD PMID:24576310 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 decreases expression
increases activity
increases expression		 EXP
ISO		 Dichlorodiphenyl Dichloroethylene results in decreased expression of CASP8 protein
Dichlorodiphenyl Dichloroethylene results in increased activity of CASP8 protein
Dichlorodiphenyl Dichloroethylene results in increased expression of CASP8 mRNA		 CTD PMID:19545618 PMID:19644561 PMID:20025943 PMID:21384494 PMID:24576310 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CASP8AP2 mRNA CTD PMID:24576310 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Casp9 caspase 9 increases activity
increases expression		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in increased activity of CASP9 protein
Dichlorodiphenyl Dichloroethylene results in increased expression of CASP9 mRNA		 CTD PMID:19545618 PMID:21384494 PMID:24576310 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases activity
multiple interactions		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in decreased activity of CAT protein
[Polychlorinated Biphenyls co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Chlordan co-treated with nonachlor] inhibits the reaction [Fish Oils results in increased expression of CAT mRNA]		 CTD PMID:25386960 PMID:28659405 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccdc85a coiled-coil domain containing 85A increases methylation ISO Dichlorodiphenyl Dichloroethylene results in increased methylation of CCDC85A gene CTD PMID:30822522 NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression		 ISO CTNNB1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 protein]; fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 mRNA]; GLI1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 protein]
Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 protein		 CTD PMID:20206645 PMID:25386960 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of CD36 mRNA] CTD PMID:25541407 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd38 CD38 molecule decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of CD38 mRNA CTD PMID:15885261 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986 		JBrowse link
G Cd40lg CD40 ligand affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of CD40LG mRNA CTD PMID:24576310 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CD44 mRNA CTD PMID:25607892 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd81 Cd81 molecule multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CD81 mRNA CTD PMID:25607892 NCBI chr 1:198,235,861...198,251,660
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [endotoxin, Escherichia coli results in increased expression of CD86 protein] CTD PMID:28412309 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdh2 cadherin 2 decreases expression
increases expression		 EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of CDH2 protein
Dichlorodiphenyl Dichloroethylene results in increased expression of CDH2 mRNA		 CTD PMID:23501609 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases activity ISO Dichlorodiphenyl Dichloroethylene results in decreased activity of CEBPA protein CTD PMID:27589886 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases activity ISO Dichlorodiphenyl Dichloroethylene results in decreased activity of CEBPB protein CTD PMID:27589886 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide multiple interactions ISO Dichlorodiphenyl Dichloroethylene affects the reaction [CGA protein results in increased expression of AR mRNA] CTD PMID:27391359 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Chga chromogranin A multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CHGA mRNA CTD PMID:25607892 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of CHRM2 mRNA] CTD PMID:28572628 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of CHRNA3 mRNA] CTD PMID:28572628 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Clock clock circadian regulator increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of CLOCK protein CTD PMID:27589886 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Clu clusterin increases expression
multiple interactions		 EXP
ISO		 Dichlorodiphenyl Dichloroethylene results in increased expression of CLU mRNA
Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dihydrotestosterone results in decreased expression of CLU mRNA]		 CTD PMID:9007049 PMID:21291947 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of CPT1A mRNA CTD PMID:28397872 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 multiple interactions EXP [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CRABP1 mRNA CTD PMID:30415545 NCBI chr 8:55,138,363...55,159,360
Ensembl chr 8:55,151,285...55,159,360 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases activity ISO Dichlorodiphenyl Dichloroethylene results in decreased activity of CREB1 protein CTD PMID:27589886 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of CREBBP protein CTD PMID:22609851 PMID:27589886 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crem cAMP responsive element modulator increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of CREM protein CTD PMID:27589886 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions ISO
EXP		 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CRH mRNA
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of CRH mRNA		 CTD PMID:32518293 PMID:34383603 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CRHR1 mRNA CTD PMID:32518293 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects activity
increases activity		 ISO CTNNB1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 protein]; CTNNB1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of MYC protein]
Dichlorodiphenyl Dichloroethylene affects the activity of CTNNB1 protein
Dichlorodiphenyl Dichloroethylene results in increased activity of CTNNB1 protein		 CTD PMID:25386960 PMID:27589886 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYBA mRNA CTD PMID:25386960 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression		 EXP Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CYCS mRNA] CTD PMID:21281706 PMID:21384494 PMID:25410718 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP
ISO		 [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of CYP11A1 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP11A1 mRNA		 CTD PMID:32518293 PMID:34000504 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of CYP11B1 mRNA CTD PMID:34000504 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of CYP11B2 mRNA CTD PMID:34000504 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of CYP17A1 mRNA CTD PMID:34000504 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases activity
decreases expression
increases expression
decreases activity		 ISO
EXP		 [Dichlorodiphenyl Dichloroethylene co-treated with bisphenol A] results in decreased activity of CYP19A1 protein; [Dichlorodiphenyl Dichloroethylene co-treated with Chlordecone] results in increased activity of CYP19A1 protein; [Dichlorodiphenyl Dichloroethylene co-treated with FSHB protein] results in increased activity of CYP19A1 protein; [Dichlorodiphenyl Dichloroethylene co-treated with nonylphenol] results in increased activity of CYP19A1 protein; [Dichlorodiphenyl Dichloroethylene co-treated with o,p'-DDT] results in decreased activity of CYP19A1 protein; Dichlorodiphenyl Dichloroethylene results in increased expression of and results in increased activity of CYP19A1 protein
Dichlorodiphenyl Dichloroethylene results in increased activity of CYP19A1 protein
Dichlorodiphenyl Dichloroethylene results in decreased expression of CYP19A1 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of CYP19A1 mRNA
Dichlorodiphenyl Dichloroethylene results in decreased activity of CYP19A1 protein
[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA		 CTD PMID:12035542 PMID:15070871 PMID:16077170 PMID:17599374 PMID:20924025 More... NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
increases methylation		 EXP
ISO		 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CYP1A1 mRNA; [Polychlorinated Biphenyls co-treated with DDT co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CYP1A1 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of CYP1A1
Dichlorodiphenyl Dichloroethylene results in increased methylation of CYP1A1 gene		 CTD PMID:16036770 PMID:21512963 PMID:24878560 PMID:30822522 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYP1B1 mRNA CTD PMID:16040568 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYP27A1 mRNA CTD PMID:28392238 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CYP2B1; Dichlorodiphenyl Dichloroethylene results in increased expression of CYP2B1 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of CYP2B1 protein CTD PMID:12869653 PMID:21512963 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYP2B6 mRNA
[CYP2B6 gene SNP affects the susceptibility to DDT] which affects the abundance of Dichlorodiphenyl Dichloroethylene; CYP2B6 gene SNP affects the reaction [DDT results in increased abundance of Dichlorodiphenyl Dichloroethylene]		 CTD PMID:20686338 PMID:27839851 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYP3A4 mRNA CTD PMID:20686338 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
multiple interactions		 EXP Dichlorodiphenyl Dichloroethylene results in increased expression of CYP3A23-3A1 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of CYP3A23-3A1 protein
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CYP3A23-3A1 mRNA		 CTD PMID:12869653 PMID:24878560 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYP7A1 mRNA CTD PMID:28392238 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of CYP8B1 mRNA CTD PMID:28392238 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DCC mRNA CTD PMID:25607892 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of DDIT3 protein CTD PMID:27589886 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions
decreases expression		 ISO [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DGAT2 mRNA
Dichlorodiphenyl Dichloroethylene results in decreased expression of DGAT2 mRNA		 CTD PMID:38092172 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of DHCR7 mRNA CTD PMID:34000504 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DIO2 mRNA CTD PMID:24878560 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions ISO [Environmental Pollutants results in increased abundance of Dichlorodiphenyl Dichloroethylene] which results in increased methylation of DIO3 promoter CTD PMID:31272017 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Dis3l DIS3-like exosome 3'-5' exoribonuclease decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of DIS3L mRNA; Dichlorodiphenyl Dichloroethylene results in decreased expression of DIS3L protein CTD PMID:32892578 NCBI chr 8:64,803,925...64,840,306
Ensembl chr 8:64,803,927...64,840,165 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DLG1 mRNA CTD PMID:25607892 NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of DLG4 mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DLG4 mRNA CTD PMID:25607892 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlgap3 DLG associated protein 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DLGAP3 mRNA CTD PMID:25607892 NCBI chr 5:139,491,972...139,562,625
Ensembl chr 5:139,492,947...139,562,625 		JBrowse link
G Dlgap4 DLG associated protein 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DLGAP4 mRNA CTD PMID:25607892 NCBI chr 3:145,124,189...145,271,791
Ensembl chr 3:145,175,479...145,270,490 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of DMP1 mRNA CTD PMID:19000923 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323 		JBrowse link
G Dnm1 dynamin 1 multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of DNM1 mRNA CTD PMID:34383603 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of DNMT1 mRNA CTD PMID:30153481 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of DNMT3A mRNA CTD PMID:30153481 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Doc2a double C2 domain alpha multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DOC2A mRNA CTD PMID:25607892 NCBI chr 1:181,457,415...181,462,528
Ensembl chr 1:181,458,390...181,462,030 		JBrowse link
G Dpp10 dipeptidyl peptidase like 10 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DPP10 mRNA CTD PMID:25607892 NCBI chr13:34,584,420...36,269,292
Ensembl chr13:34,595,868...36,269,292 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions EXP [Dichlorodiphenyl Dichloroethylene co-treated with Dietary Fats] results in increased expression of DPP4 mRNA CTD PMID:28572628 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpp6 dipeptidyl peptidase like 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of DPP6 mRNA CTD PMID:25607892 NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DPYD mRNA CTD PMID:25607892 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of EBP mRNA CTD PMID:16498641 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Egf epidermal growth factor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGF mRNA CTD PMID:25607892 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA CTD PMID:28263720 NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900 		JBrowse link
G Epha8 Eph receptor A8 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA CTD PMID:28263720 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB2 mRNA CTD PMID:25607892 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions ISO
EXP		 [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ERBB3 mRNA
[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ERBB3 mRNA		 CTD PMID:19422813 PMID:25607892 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ERBB4 mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ERBB4 mRNA CTD PMID:25607892 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
affects binding
decreases expression
increases expression		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene analog results in increased activity of ESR1 protein; Dichlorodiphenyl Dichloroethylene results in increased activity of ESR1 protein
Dichlorodiphenyl Dichloroethylene binds to and results in increased activity of ESR1 protein; Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Dihydrotestosterone co-treated with Estradiol] results in decreased expression of ESR1 protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Estradiol binds to ESR1 protein]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of ESR1 mRNA]
Dichlorodiphenyl Dichloroethylene binds to ESR1 protein; Dichlorodiphenyl Dichloroethylene metabolite binds to ESR1 protein
[Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in increased expression of ESR1 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of ESR1 mRNA
[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR1 protein; [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of ESR1 mRNA		 CTD PMID:9860891 PMID:10492897 PMID:14579009 PMID:15064155 PMID:16758953 More... NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 increases activity
affects binding
multiple interactions		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene analog results in increased activity of ESR2 protein
Dichlorodiphenyl Dichloroethylene binds to ESR2 protein
Dichlorodiphenyl Dichloroethylene results in increased activity of ESR2 protein
[o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ESR2 mRNA		 CTD PMID:9860891 PMID:15064155 PMID:17713618 PMID:32518293 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of FABP1 mRNA CTD PMID:38092172 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:26200599 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fas Fas cell surface death receptor increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of FAS mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of FAS protein CTD PMID:20025943 PMID:21384494 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression		 EXP Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein]
Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein		 CTD PMID:16921742 PMID:19644561 PMID:20025943 PMID:21384494 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
decreases expression		 ISO [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of FASN mRNA
Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA]
Dichlorodiphenyl Dichloroethylene results in increased expression of FASN protein
Dichlorodiphenyl Dichloroethylene results in increased expression of FASN mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of FASN protein
Dichlorodiphenyl Dichloroethylene results in decreased expression of FASN mRNA		 CTD PMID:25541407 PMID:26200599 PMID:27203212 PMID:28397872 PMID:38092172 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of FGF15 mRNA CTD PMID:28392238 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of FGFR4 mRNA CTD PMID:15885261 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FKBP5 mRNA CTD PMID:32518293 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FMR1 mRNA CTD PMID:25607892 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Folh1 folate hydrolase 1 multiple interactions
increases expression		 ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in decreased expression of FOLH1 mRNA]
Dichlorodiphenyl Dichloroethylene results in increased expression of FOLH1 protein		 CTD PMID:25682698 NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of FOS protein CTD PMID:27589886 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxc1 forkhead box C1 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of FOXC1 protein CTD PMID:27589886 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxc2 forkhead box C2 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of FOXC2 protein CTD PMID:27589886 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Foxo3 forkhead box O3 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of FOXO3 protein CTD PMID:27589886 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Foxo4 forkhead box O4 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of FOXO4 protein CTD PMID:27589886 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO [Dichlorodiphenyl Dichloroethylene co-treated with FSHB protein] results in increased activity of CYP19A1 protein; Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:15070871 PMID:26895433 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression
increases expression
multiple interactions		 EXP
ISO		 Dichlorodiphenyl Dichloroethylene results in decreased expression of FSHR protein
Dichlorodiphenyl Dichloroethylene results in increased expression of FSHR mRNA
Dichlorodiphenyl Dichloroethylene promotes the reaction [[FSHB protein results in increased activity of FSHR protein] which results in increased abundance of Cyclic AMP]		 CTD PMID:23501609 PMID:26895433 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FYN mRNA CTD PMID:25607892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRA4 mRNA CTD PMID:25607892 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GABRB1 mRNA CTD PMID:25607892 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of GAL mRNA] CTD PMID:28572628 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galr1 galanin receptor 1 multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of GALR1 mRNA] CTD PMID:28572628 NCBI chr18:75,772,021...75,787,577
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Gck glucokinase increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of GCK mRNA CTD PMID:36674557 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression		 ISO Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]
Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA; Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein		 CTD PMID:25263748 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GDNF mRNA CTD PMID:25607892 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA CTD PMID:28263720 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of GIPC1 mRNA CTD PMID:15885261 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Gli1 GLI family zinc finger 1 multiple interactions
increases expression		 ISO GLI1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CCND1 protein]; GLI1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of MYC protein]
Dichlorodiphenyl Dichloroethylene results in increased expression of GLI1 protein		 CTD PMID:25386960 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gls glutaminase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GLS mRNA CTD PMID:25607892 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of GLYAT mRNA CTD PMID:15885261 NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in increased expression of GNRH1 mRNA CTD PMID:16758953 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of GPX1 protein CTD PMID:31022254 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression
increases expression		 EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of GPX4 protein
Dichlorodiphenyl Dichloroethylene results in increased expression of GPX4 mRNA		 CTD PMID:25410718 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIA2 mRNA CTD PMID:25607892 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIA4 mRNA CTD PMID:25607892 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRID2 mRNA CTD PMID:34383603 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIK1 mRNA CTD PMID:25607892 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIK2 mRNA CTD PMID:25607892 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN1 mRNA CTD PMID:25607892 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions EXP
ISO		 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of GRIN2B mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIN2B mRNA		 CTD PMID:25607892 PMID:32518293 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of GRIN2D mRNA CTD PMID:34383603 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grip1 glutamate receptor interacting protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIP1 mRNA CTD PMID:25607892 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects activity ISO Dichlorodiphenyl Dichloroethylene affects the activity of GSK3B protein CTD PMID:25386960 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G H19 H19 imprinted maternally expressed transcript multiple interactions
decreases expression
increases expression
decreases methylation		 EXP [Dichlorodiphenyl Dichloroethylene results in decreased methylation of H19 gene] which results in increased expression of H19 mRNA
Dichlorodiphenyl Dichloroethylene results in decreased expression of H19 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of H19 mRNA		 CTD PMID:28867213 PMID:30153481 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects binding ISO Dichlorodiphenyl Dichloroethylene binds to HBA1 protein CTD PMID:32278787 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbg1 hemoglobin subunit gamma 1 decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of HBG1 mRNA CTD PMID:16498641 NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HES6 mRNA CTD PMID:25607892 NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of HNRNPH1 protein CTD PMID:26186133 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hpgds hematopoietic prostaglandin D synthase affects binding ISO Dichlorodiphenyl Dichloroethylene binds to HPGDS protein CTD PMID:32278787 NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883 		JBrowse link
G Hrk harakiri, BCL2 interacting protein affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of HRK mRNA CTD PMID:24576310 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased expression of HSD3B1 mRNA; [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased expression of HSD3B1 protein; STF-31 inhibits the reaction [[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased expression of HSD3B1 protein] CTD PMID:34311058 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of HSPB1 mRNA CTD PMID:15885261 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of HTR1A mRNA CTD PMID:32518293 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HTR2A mRNA CTD PMID:32518293 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of IDI1 mRNA CTD PMID:16498641 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of ARG1 mRNA] CTD PMID:26748080 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of IGF1 mRNA] CTD PMID:25682698 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased phosphorylation of IGF1R protein CTD PMID:33571556 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases methylation
decreases expression		 EXP Dichlorodiphenyl Dichloroethylene results in decreased methylation of IGF2 gene
Dichlorodiphenyl Dichloroethylene results in decreased expression of IGF2 mRNA		 CTD PMID:25187598 PMID:28867213 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of IGF2R mRNA CTD PMID:25607892 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Il1b interleukin 1 beta decreases expression
increases secretion
decreases secretion		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in decreased expression of IL1B mRNA
Dichlorodiphenyl Dichloroethylene results in increased secretion of IL1B protein
Dichlorodiphenyl Dichloroethylene results in decreased secretion of IL1B protein		 CTD PMID:12007859 PMID:28572628 PMID:37236336 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rapl1 interleukin 1 receptor accessory protein-like 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of IL1RAPL1 mRNA CTD PMID:25607892 NCBI chr  X:51,371,969...52,876,726
Ensembl chr  X:51,378,215...52,876,772 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO [DDT co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of IL4 protein
Dichlorodiphenyl Dichloroethylene promotes the reaction [IL4 protein results in increased expression of ARG1 mRNA]		 CTD PMID:12696651 PMID:26748080 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Inha inhibin subunit alpha multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of INHA mRNA CTD PMID:34000504 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhbb inhibin subunit beta B decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of INHBB mRNA CTD PMID:16519141 PMID:19877505 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Ins1 insulin 1 increases secretion
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased secretion of INS1 protein
[Glucose co-treated with Dichlorodiphenyl Dichloroethylene] results in increased secretion of INS1 protein		 CTD PMID:34225579 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression		 ISO [Dichlorodiphenyl Dichloroethylene co-treated with [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of PPARG mRNA; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FASN mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of LEP mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SLC2A4 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Glucose results in increased secretion of INS protein]
Dichlorodiphenyl Dichloroethylene results in decreased expression of INS2 mRNA		 CTD PMID:26200599 PMID:35457000 PMID:35563431 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Insl3 insulin-like 3 multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of INSL3 mRNA CTD PMID:34000504 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Isl1 ISL LIM homeobox 1 multiple interactions EXP [Dichlorodiphenyl Dichloroethylene co-treated with Dietary Fats] results in increased expression of ISL1 mRNA CTD PMID:28572628 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP [beta-hexachlorocyclohexane co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of JUN mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of JUN mRNA		 CTD PMID:18481421 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of KISS1 mRNA CTD PMID:34383603 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of KIT mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA CTD PMID:19422813 PMID:28263720 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions
affects expression		 ISO [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] promotes the reaction [AR protein mutant form binds to KLK3 enhancer]; [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased expression of KLK3 mRNA; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone promotes the reaction [AR protein binds to KLK3 promoter]]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Metribolone results in increased expression of KLK3 protein]
Dichlorodiphenyl Dichloroethylene affects the expression of KLK3 mRNA		 CTD PMID:18819937 PMID:25682698 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Krt18 keratin 18 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of KRT18 protein CTD PMID:26186133 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of LDLR mRNA CTD PMID:15885261 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin increases secretion
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased secretion of LEP protein
Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of LEP mRNA]		 CTD PMID:21044676 PMID:26200599 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of LHCGR mRNA CTD PMID:34000504 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lhx4 LIM homeobox 4 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of LHX4 mRNA; Dichlorodiphenyl Dichloroethylene results in decreased expression of LHX4 protein CTD PMID:32892578 NCBI chr13:67,877,109...67,917,219
Ensembl chr13:67,877,109...67,927,003 		JBrowse link
G Lrrc2 leucine rich repeat containing 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA CTD PMID:28263720 NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185 		JBrowse link
G Lrrc7 leucine rich repeat containing 7 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of LRRC7 mRNA CTD PMID:25607892 NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547 		JBrowse link
G Mafa MAF bZIP transcription factor A decreases expression
increases expression		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in decreased expression of MAFA mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of MAFA mRNA		 CTD PMID:35457000 PMID:35563431 NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690 		JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MAGI2 mRNA CTD PMID:25607892 NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha affects expression
increases expression		 ISO Dichlorodiphenyl Dichloroethylene affects the expression of MAP1LC3A mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of MAP1LC3A protein		 CTD PMID:32721735 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of MAP1LC3B mRNA CTD PMID:32721735 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity
multiple interactions
increases phosphorylation		 EXP
ISO		 Dichlorodiphenyl Dichloroethylene results in increased activity of MAPK1 protein
[Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of MAPK1 protein
Dichlorodiphenyl Dichloroethylene results in increased phosphorylation of MAPK1 protein		 CTD PMID:12523960 PMID:15531431 PMID:17174995 PMID:18819937 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO
EXP		 [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of MAPK3 protein
Dichlorodiphenyl Dichloroethylene results in increased phosphorylation of MAPK3 protein		 CTD PMID:15531431 PMID:18819937 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mc2r melanocortin 2 receptor multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of MC2R mRNA CTD PMID:32518293 NCBI chr18:62,001,980...62,015,567
Ensembl chr18:62,004,948...62,015,488 		JBrowse link
G Mdga2 MAM domain containing glycosylphosphatidylinositol anchor 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA CTD PMID:25607892 NCBI chr 6:84,746,422...85,608,640
Ensembl chr 6:84,761,941...85,608,126 		JBrowse link
G Meg3 maternally expressed 3 multiple interactions
decreases methylation
increases expression		 EXP [Dichlorodiphenyl Dichloroethylene results in decreased methylation of MEG3 gene] which results in increased expression of MEG3 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of MEG3 mRNA		 CTD PMID:30153481 NCBI chr 6:128,491,808...128,524,010 JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA CTD PMID:28263720 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased expression of and results in increased activity of MMP2 protein; [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased expression of MMP2 mRNA; picropodophyllin inhibits the reaction [[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased activity of MMP2 protein] CTD PMID:33571556 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmrn1 multimerin 1 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of MMRN1 mRNA CTD PMID:15885261 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474 		JBrowse link
G Msmb microseminoprotein, beta increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of MSMB mRNA CTD PMID:15885261 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of MSMO1 mRNA CTD PMID:16498641 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mt2A metallothionein 2A increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of MT2A mRNA CTD PMID:15885261 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression
multiple interactions
increases activity		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of MYC protein
CTNNB1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of MYC protein]; GLI1 affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of MYC protein]
Dichlorodiphenyl Dichloroethylene results in increased activity of MYC protein		 CTD PMID:25386960 PMID:27589886 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NCF1 mRNA
Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of NCF1 mRNA]		 CTD PMID:25386960 PMID:28273962 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NCF2 mRNA CTD PMID:25386960 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NCF4 mRNA CTD PMID:25386960 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389 		JBrowse link
G Nf1 neurofibromin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NF1 mRNA CTD PMID:25607892 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA; Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein
Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]		 CTD PMID:25263748 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NFKB1 protein CTD PMID:19545618 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation ISO Dichlorodiphenyl Dichloroethylene results in increased phosphorylation of NFKBIA protein CTD PMID:19545618 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlgn1 neuroligin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NLGN1 mRNA CTD PMID:25607892 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nmu neuromedin U multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of NMU mRNA] CTD PMID:28572628 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP [Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NOS1 mRNA; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of NOS1 mRNA] CTD PMID:28572628 PMID:30415545 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of NOS2 mRNA
Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA]		 CTD PMID:12007859 PMID:26748080 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NOS3 mRNA
Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of NOS3 mRNA]		 CTD PMID:28273962 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch2 notch receptor 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NOTCH2 mRNA CTD PMID:25607892 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Notch3 notch receptor 3 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NOTCH3 mRNA CTD PMID:25607892 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Notch4 notch receptor 4 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NOTCH4 mRNA CTD PMID:25607892 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Nox1 NADPH oxidase 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NOX1 mRNA CTD PMID:25386960 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of NR0B1 mRNA CTD PMID:34000504 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NR1H4 mRNA CTD PMID:28392238 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions
increases activity		 EXP
ISO		 Dichlorodiphenyl Dichloroethylene results in increased expression of NR1I2 mRNA
Dichlorodiphenyl Dichloroethylene binds to and results in increased activity of NR1I2 protein
Dichlorodiphenyl Dichloroethylene results in increased activity of NR1I2 protein		 CTD PMID:12869653 PMID:20686338 PMID:21115097 PMID:25680588 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
increases activity
multiple interactions
affects response to substance		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in increased expression of NR1I3 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of NR1I3 protein
Dichlorodiphenyl Dichloroethylene results in increased activity of NR1I3 protein
Dichlorodiphenyl Dichloroethylene inhibits the reaction [Androstenols results in decreased activity of NR1I3 protein]
NR1I3 protein affects the susceptibility to Dichlorodiphenyl Dichloroethylene		 CTD PMID:12869653 PMID:16929008 PMID:19746742 PMID:28927721 PMID:32721735 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases activity		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene inhibits the reaction [Hydrocortisone results in increased activity of NR3C1 protein]
Dichlorodiphenyl Dichloroethylene results in increased activity of NR3C1 protein
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NR3C1 mRNA
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of NR3C1 mRNA		 CTD PMID:26647222 PMID:27589886 PMID:32518293 PMID:34383603 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions
decreases expression		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone affects the localization of NR3C2 protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased activity of NR3C2 protein]
Dichlorodiphenyl Dichloroethylene results in decreased expression of NR3C2 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NR3C2 mRNA		 CTD PMID:29149346 PMID:30415545 PMID:32518293 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of NR4A1 protein CTD PMID:27589886 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of NR4A2 protein CTD PMID:27589886 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nrcam neuronal cell adhesion molecule multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NRCAM mRNA CTD PMID:25607892 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NRG1 mRNA; [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NRG1 mRNA CTD PMID:25607892 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrxn1 neurexin 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of NRXN1 mRNA CTD PMID:25607892 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Nrxn2 neurexin 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NRXN2 mRNA CTD PMID:25607892 NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA CTD PMID:28263720 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP
ISO		 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NTRK2 mRNA
[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA		 CTD PMID:25607892 PMID:28263720 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nup62 nucleoporin 62 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of NUP62 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of NUP62 protein CTD PMID:32721735 NCBI chr 1:95,298,995...95,314,902
Ensembl chr 1:95,295,526...95,315,174 		JBrowse link
G Or10al27 olfactory receptor family 10 subfamily AL member 27 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of OR10AL27 mRNA CTD PMID:15885261 NCBI chr20:789,272...790,237
Ensembl chr20:761,025...765,744
Ensembl chr20:761,025...765,744 		JBrowse link
G Or13p4 olfactory receptor family 13 subfamily P member 4 increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of OR13P4 mRNA CTD PMID:15885261 NCBI chr 5:132,216,822...132,217,769
Ensembl chr 5:132,215,327...132,221,481 		JBrowse link
G Or9s23b olfactory receptor family 9 subfamily S member 23B increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of OR9S23B mRNA CTD PMID:15885261 NCBI chr 9:93,117,328...93,118,299
Ensembl chr 9:93,115,232...93,123,441 		JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of ORM1 mRNA CTD PMID:19000923 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions ISO
EXP		 [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXT mRNA
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of OXT mRNA		 CTD PMID:32518293 PMID:34383603 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Oxtr oxytocin receptor multiple interactions ISO [diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXTR mRNA CTD PMID:32518293 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO Dichlorodiphenyl Dichloroethylene results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of PARP1 protein CTD PMID:19545618 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Hydrocortisone results in increased expression of PCK1 mRNA] CTD PMID:26647222 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha multiple interactions ISO [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRA mRNA CTD PMID:19422813 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Dichlorodiphenyldichloroethane co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of PDGFRB mRNA; [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA CTD PMID:19422813 PMID:28263720 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pgr progesterone receptor affects binding
multiple interactions
increases expression		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene binds to PGR protein
Dichlorodiphenyl Dichloroethylene inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Progesterone binds to PGR protein]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [Progesterone results in increased expression of PGR protein]; fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of PGR mRNA]
Dichlorodiphenyl Dichloroethylene results in increased expression of PGR mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of PGR protein
[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PGR mRNA		 CTD PMID:14579009 PMID:16859517 PMID:18262749 PMID:20206645 PMID:25607892 More... NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Plin2 perilipin 2 multiple interactions ISO [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 protein; Dichlorodiphenyl Dichloroethylene promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein] CTD PMID:38092172 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plxnd1 plexin D1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA CTD PMID:28263720 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244 		JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO
EXP		 [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in decreased expression of POMC mRNA
[Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] affects the expression of POMC mRNA		 CTD PMID:16758953 PMID:34383603 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [Dichlorodiphenyl Dichloroethylene co-treated with [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of PPARG mRNA CTD PMID:26200599 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of PPARGC1A protein CTD PMID:27589886 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of PPP1R1B mRNA CTD PMID:34383603 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prl prolactin increases secretion EXP Dichlorodiphenyl Dichloroethylene results in increased secretion of PRL protein CTD PMID:17174995 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptch1 patched 1 increases expression ISO Dichlorodiphenyl Dichloroethylene results in increased expression of PTCH1 mRNA CTD PMID:25386960 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of PTGS2 protein
Dichlorodiphenyl Dichloroethylene inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PTGS2 mRNA]		 CTD PMID:19545618 PMID:23132776 PMID:26748080 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pycard PYD and CARD domain containing increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of PYCARD protein CTD PMID:27589886 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of RACK1 mRNA; Dichlorodiphenyl Dichloroethylene results in decreased expression of RACK1 protein CTD PMID:28412309 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rdx radixin decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of RDX mRNA CTD PMID:16498641 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of REL protein CTD PMID:27589886 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects localization EXP Dichlorodiphenyl Dichloroethylene affects the localization of RELA protein CTD PMID:19644561 PMID:20025943 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reln reelin multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of RELN mRNA CTD PMID:25607892 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Ret ret proto-oncogene multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Retn resistin increases expression
increases secretion		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of RETN mRNA
Dichlorodiphenyl Dichloroethylene results in increased secretion of RETN protein		 CTD PMID:21044676 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of RIPK2 mRNA CTD PMID:24576310 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Robo1 roundabout guidance receptor 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of ROBO1 mRNA CTD PMID:25607892 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Runx1 RUNX family transcription factor 1 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of RUNX1 protein CTD PMID:27589886 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of RUNX3 protein CTD PMID:27589886 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions
increases expression		 EXP
ISO		 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of RXRA mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of RXRA mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of RXRA protein
RXRA mRNA promotes the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]		 CTD PMID:25607892 PMID:26563996 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Rxrb retinoid X receptor beta increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of RXRB mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of RXRB protein
RXRB mRNA promotes the reaction [Dichlorodiphenyl Dichloroethylene results in increased activity of CASP3 protein]		 CTD PMID:26563996 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773 		JBrowse link
G Ryr1 ryanodine receptor 1 affects activity ISO Dichlorodiphenyl Dichloroethylene affects the activity of RYR1 protein CTD PMID:31127943 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions EXP [Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of SCARB1 mRNA CTD PMID:34000504 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
multiple interactions
increases expression		 EXP
ISO		 Dichlorodiphenyl Dichloroethylene results in decreased expression of SCD1 mRNA
[Dietary Fats co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SCD1 mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of SCD1 protein
Dichlorodiphenyl Dichloroethylene results in increased expression of SCD1 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of SCD1 protein
[Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SCD mRNA
Dichlorodiphenyl Dichloroethylene results in decreased expression of SCD mRNA		 CTD PMID:15885261 PMID:25541407 PMID:27203212 PMID:28397872 PMID:38092172 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Scg2 secretogranin II multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of SCG2 mRNA] CTD PMID:28572628 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Sh2d4a SH2 domain containing 4A increases expression EXP Dichlorodiphenyl Dichloroethylene results in increased expression of SH2D4A mRNA CTD PMID:15885261 NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SHANK2 mRNA CTD PMID:25607892 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shbg sex hormone binding globulin multiple interactions
increases expression		 EXP Dichlorodiphenyl Dichloroethylene analog inhibits the reaction [Dihydrotestosterone binds to SHBG protein]
Dichlorodiphenyl Dichloroethylene results in increased expression of SHBG mRNA		 CTD PMID:9171990 PMID:16380112 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of SLC10A2 mRNA CTD PMID:28392238 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO [Environmental Pollutants results in increased abundance of Dichlorodiphenyl Dichloroethylene] which results in increased methylation of SLC16A2 promoter CTD PMID:31272017 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A2 mRNA CTD PMID:25607892 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a6 solute carrier family 1 member 6 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLC1A6 mRNA CTD PMID:25607892 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of SLC2A1 mRNA CTD PMID:36674557 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in decreased expression of SLC2A4 mRNA]
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in decreased expression of SLC2A4 mRNA; [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in decreased expression of SLC2A4 protein; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SLC2A4 mRNA]; STF-31 inhibits the reaction [[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in decreased expression of SLC2A4 mRNA]; STF-31 inhibits the reaction [[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in decreased expression of SLC2A4 protein]		 CTD PMID:25541407 PMID:26200599 PMID:34311058 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc51a solute carrier family 51 member A decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of SLC51A mRNA CTD PMID:28392238 NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485 		JBrowse link
G Slc51b SLC51 subunit beta decreases expression ISO Dichlorodiphenyl Dichloroethylene results in decreased expression of SLC51B mRNA CTD PMID:28392238 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions EXP
ISO		 [Dichlorodiphenyl Dichloroethylene co-treated with Estradiol] promotes the reaction [SLC6A3 protein affects the export of Dopamine]; Dichlorodiphenyl Dichloroethylene inhibits the reaction [SLC6A3 protein affects the export of Dopamine]
Dichlorodiphenyl Dichloroethylene inhibits the reaction [DAT protein results in increased uptake of Dopamine]		 CTD PMID:18533268 PMID:19479021 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slit1 slit guidance ligand 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SLIT1 mRNA CTD PMID:25607892 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127 		JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of SMARCB1 protein CTD PMID:27589886 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Snap25 synaptosome associated protein 25 multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of SNAP25 mRNA] CTD PMID:28572628 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in increased expression of SOD1 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of SOD1 protein
[Polychlorinated Biphenyls co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Chlordan co-treated with nonachlor] inhibits the reaction [Fish Oils results in increased expression of SOD1 mRNA]		 CTD PMID:19545618 PMID:28659405 PMID:31022254 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 EXP Dietary Fats inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of SOD2 protein]; Dietary Fats promotes the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of SOD2 protein] CTD PMID:31022254 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SPTBN2 mRNA CTD PMID:25607892 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases activity ISO Dichlorodiphenyl Dichloroethylene results in decreased activity of SRD5A2 protein CTD PMID:17218080 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
decreases expression		 ISO [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SREBF1 mRNA; Dichlorodiphenyl Dichloroethylene promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]
Dichlorodiphenyl Dichloroethylene results in increased expression of SREBF1 protein
Dichlorodiphenyl Dichloroethylene results in decreased expression of SREBF1 mRNA		 CTD PMID:26200599 PMID:27203212 PMID:38092172 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Sst somatostatin multiple interactions EXP Dichlorodiphenyl Dichloroethylene inhibits the reaction [Dietary Fats results in increased expression of SST mRNA] CTD PMID:28572628 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions		 EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of STAR mRNA
[Pesticides co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Phthalic Acids] results in decreased expression of STAR mRNA		 CTD PMID:16498641 PMID:34000504 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases activity ISO Dichlorodiphenyl Dichloroethylene results in decreased activity of STAT3 protein CTD PMID:27589886 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of STAT5B protein CTD PMID:27589886 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stmn2 stathmin 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of STMN2 mRNA CTD PMID:25607892 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011 		JBrowse link
G Sts steroid sulfatase multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of STS mRNA CTD PMID:25607892 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Stxbp1 syntaxin binding protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of STXBP1 mRNA CTD PMID:25607892 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Syngap1 synaptic Ras GTPase activating protein 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of SYNGAP1 mRNA CTD PMID:25607892 NCBI chr20:5,026,366...5,056,659
Ensembl chr20:5,026,364...5,056,672 		JBrowse link
G Syp synaptophysin multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of SYP mRNA CTD PMID:25607892 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tf transferrin decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of TF mRNA CTD PMID:16380112 PMID:16519141 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfam transcription factor A, mitochondrial increases activity ISO Dichlorodiphenyl Dichloroethylene results in increased activity of TFAM protein CTD PMID:27589886 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tff1 trefoil factor 1 increases expression
multiple interactions		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of TFF1 mRNA
[Dichlorodiphenyl Dichloroethylene co-treated with Dihydrotestosterone co-treated with Estradiol] results in increased expression of TFF1 mRNA; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of TFF1 mRNA]		 CTD PMID:18275596 PMID:20206645 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tg thyroglobulin multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of TG protein CTD PMID:24878560 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of TGFB1 mRNA CTD PMID:25607892 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Plasticizers co-treated with Fungicides, Industrial co-treated with Linuron co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with Dichlorodiphenyl Dichloroethylene co-treated with butylparaben co-treated with Acetaminophen] results in decreased expression of TH mRNA CTD PMID:34383603 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thra thyroid hormone receptor alpha increases expression
multiple interactions		 EXP Dichlorodiphenyl Dichloroethylene results in increased expression of THRA mRNA
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of THRA mRNA		 CTD PMID:21512963 PMID:24878560 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta increases expression
multiple interactions		 EXP Dichlorodiphenyl Dichloroethylene results in increased expression of THRB mRNA
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of THRB mRNA		 CTD PMID:21512963 PMID:24878560 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
multiple interactions		 ISO
EXP		 Dichlorodiphenyl Dichloroethylene results in decreased expression of TNF mRNA
Dichlorodiphenyl Dichloroethylene results in increased expression of TNF protein
Dichlorodiphenyl Dichloroethylene results in increased expression of TNF mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of TNF protein
Dichlorodiphenyl Dichloroethylene inhibits the reaction [endotoxin, Escherichia coli results in increased expression of TNF protein]; TNF protein affects the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of AHR mRNA]		 CTD PMID:12007859 PMID:19545618 PMID:24576310 PMID:25316167 PMID:28412309 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of TNFRSF11B mRNA CTD PMID:24576310 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of TNFRSF1B mRNA CTD PMID:24576310 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 affects expression EXP Dichlorodiphenyl Dichloroethylene affects the expression of TNFRSF10B mRNA CTD PMID:24576310 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309 		JBrowse link
G Tp53 tumor protein p53 increases expression
increases activity		 ISO Dichlorodiphenyl Dichloroethylene results in increased expression of TP53 mRNA
Dichlorodiphenyl Dichloroethylene results in increased activity of TP53 protein		 CTD PMID:19545618 PMID:27589886 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trhr thyrotropin releasing hormone receptor multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of TRHR mRNA CTD PMID:24878560 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309 		JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of TSC2 mRNA CTD PMID:25607892 NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions
increases activity		 ISO Dichlorodiphenyl Dichloroethylene inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]
Dichlorodiphenyl Dichloroethylene results in increased activity of TSC22D3 protein		 CTD PMID:26647222 PMID:27589886 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP
ISO		 [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of TSHB protein
Dichlorodiphenyl Dichloroethylene affects the expression of and affects the secretion of TSHB protein		 CTD PMID:19750101 PMID:24878560 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Ttr transthyretin decreases expression
multiple interactions		 EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of TTR protein
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of TTR protein		 CTD PMID:21512963 PMID:24878560 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions
increases expression		 EXP Dichlorodiphenyl Dichloroethylene promotes the reaction [Dietary Fats results in increased expression of UCP2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Dietary Fats results in increased expression of UCP2 protein]; Dietary Fats inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 mRNA]; Dietary Fats inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 protein]
Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 protein		 CTD PMID:31022254 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 multiple interactions EXP [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of UGT2B17 mRNA CTD PMID:24878560 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Unc5b unc-5 netrin receptor B multiple interactions EXP [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of UNC5B mRNA CTD PMID:25607892 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions ISO [Dichlorodiphenyl Dichloroethylene results in increased activity of AR protein mutant form] which results in increased phosphorylation of VASP protein CTD PMID:18819937 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
G Vim vimentin decreases expression EXP Dichlorodiphenyl Dichloroethylene results in decreased expression of VIM protein CTD PMID:23501609 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      chemical role 19420
        environmental contaminant 18825
          persistent organic pollutant 16665
            DDE 367
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                carbocyclic compound 18559
                                  benzenoid aromatic compound 17968
                                    benzenes 17830
                                      chlorobenzenes 14817
                                        monochlorobenzenes 11624
                                          DDE 367
paths to the root