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Gene: Hpgds (hematopoietic prostaglandin D synthase) Rattus norvegicus

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Symbol:

Hpgds

Name:

hematopoietic prostaglandin D synthase

RGD ID:

69251

Description:

Predicted to enable several functions, including glutathione transferase activity; metal ion binding activity; and prostaglandin-D synthase activity. Predicted to be involved in glutathione metabolic process and prostaglandin metabolic process. Predicted to act upstream of or within negative regulation of male germ cell proliferation; response to nematode; and response to selenium ion. Predicted to be located in cytosol and nucleoplasm. Orthologous to human HPGDS (hematopoietic prostaglandin D synthase); PARTICIPATES IN prostanoid metabolic pathway; prostaglandin biosynthetic pathway; arachidonic acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

glutathione S-transferase; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; glutathione-requiring prostaglandin D synthase; GST class-sigma; H-PGDS; MGC105397; prostaglandin D2 synthase 2; prostaglandin D2 synthase 2 hematopoietic; prostaglandin D2 synthase 2, hematopoietic; prostaglandin-H2 D-isomerase; Ptgds2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HPGDS (hematopoietic prostaglandin D synthase)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Hpgds (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HPGDS (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HPGDS (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Hpgds (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HPGDS (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HPGDS (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hpgds (hematopoietic prostaglandin D synthase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	HPGDS (hematopoietic prostaglandin D synthase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Hpgds (hematopoietic prostaglandin D synthase)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gst-28	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-11	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	GstS1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	gst-16	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-20	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-24	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-29	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-30	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-32	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-33	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-34	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-37	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-38	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-39	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-5	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-6	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-7	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gst-8	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	hpgds	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	95,698,265 - 95,727,733 (-)	NCBI		GRCr8
mRatBN7.2	4	94,368,426 - 94,397,931 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	94,373,342 - 94,397,883 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	99,611,191 - 99,635,963 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	95,386,132 - 95,410,900 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	93,798,205 - 93,822,753 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	95,945,356 - 95,970,666 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	95,946,025 - 95,970,666 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	160,734,255 - 160,758,902 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	94,611,607 - 94,636,147 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	94,856,088 - 94,880,628 (-)	NCBI
Celera	4	89,106,678 - 89,131,218 (-)	NCBI		Celera
Cytogenetic Map	4	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

Kidney Neoplasms (ISO)

liver disease (ISO)

Testicular Germ Cell Tumor (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,7-dihydropurine-6-thione (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

6-propyl-2-thiouracil (EXP)

9-cis-retinoic acid (EXP)

aflatoxin B1 (EXP)

aldehydo-D-glucose (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bexarotene (EXP)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bupivacaine (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

choline (ISO)

coumarin (ISO)

D-glucose (ISO)

DDE (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (EXP)

diarsenic trioxide (ISO)

diprotium oxide (ISO)

disodium selenite (ISO)

ebselen (ISO)

elemental selenium (ISO)

erythrosin B (ISO)

ethanol (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

furan (EXP)

glucose (ISO)

glyphosate (EXP)

indole-3-methanol (EXP)

iron atom (ISO)

iron(0) (ISO)

isoquinolines (ISO)

L-methionine (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

mercaptopurine (EXP)

methylseleninic acid (ISO)

mifepristone (EXP)

oxaliplatin (EXP)

Oxyfluorfen (ISO)

ozone (ISO)

paracetamol (EXP)

parthenolide (ISO)

pencycuron (ISO)

pentanal (ISO)

phenobarbital (EXP)

prostaglandin D2 (ISO)

purine-6-thiol (EXP)

sanguinarine (ISO)

selenium atom (ISO)

sodium chloride (EXP)

succimer (ISO)

sulforaphane (ISO)

suramin (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

water (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid biosynthetic process (IEA)

fatty acid metabolic process (IEA)

glutathione metabolic process (IBA)

lipid metabolic process (IEA)

negative regulation of male germ cell proliferation (IEA,ISO)

prostaglandin biosynthetic process (IEA,TAS)

prostaglandin metabolic process (IEA,ISO,ISS)

response to nematode (IEA,ISO)

response to selenium ion (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (ISO)

intracellular membrane-bounded organelle (ISO)

nucleoplasm (ISO)

Molecular Function

calcium ion binding (ISO,ISS)

glutathione transferase activity (IBA,IEA)

isomerase activity (IEA)

magnesium ion binding (ISO,ISS)

prostaglandin-D synthase activity (IEA,ISO,ISS,TAS)

protein binding (ISO)

protein homodimerization activity (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

arachidonic acid metabolic pathway (IEA)

prostaglandin biosynthetic pathway (ISO)

prostanoid metabolic pathway (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Prostanoids as regulators of innate and adaptive immunity.	Hirata T and Narumiya S, Adv Immunol. 2012;116:143-74. doi: 10.1016/B978-0-12-394300-2.00005-3.
3.	Cloning and crystal structure of hematopoietic prostaglandin D synthase.	Kanaoka Y, etal., Cell 1997 Sep 19;90(6):1085-95.
4.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
5.	Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn.	Majed BH and Khalil RA, Pharmacol Rev. 2012 Jul;64(3):540-82. doi: 10.1124/pr.111.004770. Epub 2012 Jun 7.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10824118	PMID:12477932	PMID:12627223	PMID:12684506	PMID:15489334	PMID:17259069	PMID:25142465

Genomics

Comparative Map Data

Hpgds
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	95,698,265 - 95,727,733 (-)	NCBI		GRCr8
mRatBN7.2	4	94,368,426 - 94,397,931 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	94,373,342 - 94,397,883 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	99,611,191 - 99,635,963 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	95,386,132 - 95,410,900 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	93,798,205 - 93,822,753 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	95,945,356 - 95,970,666 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	95,946,025 - 95,970,666 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	160,734,255 - 160,758,902 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	94,611,607 - 94,636,147 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	94,856,088 - 94,880,628 (-)	NCBI
Celera	4	89,106,678 - 89,131,218 (-)	NCBI		Celera
Cytogenetic Map	4	q31	NCBI

HPGDS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	94,298,535 - 94,342,836 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	94,298,535 - 94,342,876 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	95,219,686 - 95,263,987 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	95,438,730 - 95,483,050 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	95,577,633 - 95,612,968	NCBI
Celera	4	92,516,831 - 92,561,280 (-)	NCBI		Celera
Cytogenetic Map	4	q22.3	NCBI
HuRef	4	90,957,458 - 91,001,835 (-)	NCBI		HuRef
CHM1_1	4	95,196,420 - 95,241,397 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	97,614,053 - 97,658,342 (-)	NCBI		T2T-CHM13v2.0

Hpgds
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	65,094,019 - 65,121,960 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	65,094,277 - 65,121,892 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	65,117,293 - 65,144,981 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	65,117,293 - 65,144,908 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	65,067,287 - 65,094,724 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	65,048,942 - 65,074,308 (-)	NCBI		MGSCv36	mm8
Celera	6	67,246,090 - 67,273,526 (-)	NCBI		Celera
Cytogenetic Map	6	C1	NCBI
cM Map	6	30.11	NCBI

HPGDS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	92,324,323 - 92,367,772 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	92,595,665 - 92,647,007 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	86,659,551 - 86,702,995 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	97,332,231 - 97,375,684 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	97,332,231 - 97,375,815 (-)	Ensembl	panpan1.1		panPan2

HPGDS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	17,172,372 - 17,196,851 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	17,121,968 - 17,196,851 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	24,752,940 - 24,777,413 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	17,315,689 - 17,375,451 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	17,351,003 - 17,375,432 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	17,323,037 - 17,347,505 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	17,137,331 - 17,161,789 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	22,730,052 - 22,754,426 (+)	NCBI		UU_Cfam_GSD_1.0

Hpgds
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	24,462,666 - 24,540,537 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936687	1,805,830 - 1,884,319 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936687	1,806,452 - 1,884,310 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HPGDS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	125,375,867 - 125,405,955 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	125,375,906 - 125,406,066 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	134,662,192 - 134,692,377 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HPGDS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	42,555,151 - 42,592,457 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	42,553,848 - 42,592,400 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	20,918,448 - 20,961,381 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hpgds
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624757	22,114,249 - 22,140,059 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624757	22,114,917 - 22,166,833 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Hpgds
147 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	249
Count of miRNA genes:	177
Interacting mature miRNAs:	198
Transcripts:	ENSRNOT00000008826
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582232	Gluco25	Glucose level QTL 25	3.6	0.0023	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	85253748	148090731	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	103194791	Rat
1578655	Bmd11	Bone mineral density QTL 11	11		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	4	90850165	135850165	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	26775591	168368347	Rat
1357342	Bw40	Body weight QTL 40		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	4	76647384	117676292	Rat
631556	Bp135	Blood pressure QTL 135		0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	78881294	117676292	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	57486946	102486946	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	70362013	132642728	Rat
70167	Bw22	Body weight QTL 22	3.1		body mass (VT:0001259)	body weight (CMO:0000012)	4	76647384	117676292	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61697658	115089733	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82798864	152731274	Rat
724522	Bp146	Blood pressure QTL 146	2.2	0.0021	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	73630210	118630210	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	86730991	131730991	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	81192555	126192555	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
2300179	Bmd50	Bone mineral density QTL 50	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	4	60928534	105928534	Rat
2317587	Eae26	Experimental allergic encephalomyelitis QTL 26			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	4	88656681	103194984	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	62933508	114921294	Rat
61364	Iddm2	Insulin dependent diabetes mellitus QTL 2			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	78885890	102684881	Rat
1578670	Bss14	Bone structure and strength QTL 14	16.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	4	87327165	132327165	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	56647873	149491524	Rat
1578657	Bss12	Bone structure and strength QTL 12	8.9		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	4	60220938	105220938	Rat
1578658	Bss13	Bone structure and strength QTL 13	8		femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	4	60220938	105220938	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
1578662	Bss15	Bone structure and strength QTL 15	19.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	4	87327165	132327165	Rat
2302051	Pia28	Pristane induced arthritis QTL 28	5.3	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	73630210	118630210	Rat
2306794	Ean2	Experimental allergic neuritis QTL 2	6.4		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	4	83428419	95853334	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	59948935	154902892	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
738015	Pia9	Pristane induced arthritis QTL 9	4.5	0.048	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	80694870	125694870	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	93308457	167139447	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	73169846	132642728	Rat
634334	Xhs3	X-ray hypersensitivity QTL 3	10		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	84728680	129854654	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	65882107	96130297	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	36303261	103194984	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	70808386	115808386	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	83428419	177635233	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	0.0003	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	78878504	123878504	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	62277855	128289560	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	62879517	107879517	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	85379421	167139601	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	56698790	126192555	Rat
2306899	Bp338	Blood pressure QTL 338		0.071	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	81006124	120102625	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	64528739	157573521	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	62753847	107753847	Rat
12798523	Anxrr56	Anxiety related response QTL 56	2.83	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	85253748	150276390	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	32583980	114627242	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	45	111	91	90	59	25	59	6	214	93	91	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039108297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063286650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF021882	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D82071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000008826 ⟹ ENSRNOP00000008826

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	94,373,342 - 94,397,883 (-)	Ensembl
Rnor_6.0 Ensembl	4	95,946,025 - 95,970,666 (-)	Ensembl

RefSeq Acc Id:

NM_031644 ⟹ NP_113832

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	95,703,179 - 95,727,721 (-)	NCBI
mRatBN7.2	4	94,373,338 - 94,397,883 (-)	NCBI
Rnor_6.0	4	95,946,023 - 95,970,666 (-)	NCBI
Rnor_5.0	4	160,734,255 - 160,758,902 (-)	NCBI
RGSC_v3.4	4	94,611,607 - 94,636,147 (-)	RGD
Celera	4	89,106,678 - 89,131,218 (-)	RGD

Sequence:

show sequence

GGAAAACGTGACAGGACTTGTTCTTATTCCCCAGAGGCCTGTGGTGTAAGACTAAGAAGAAAGA
ACATGTAGCAATCCGTACACACAAGCACCTGTGACTGCGACTTTACTCTTTATGCAAATTTGGT
GGGTATATACAGAGAGCTTGGGAAATGGTGGCAAAAGCTACCAGAGCTCCTTCCAGGCTGAACT
TTGGACGTGTGTATCTCGTGTGAGCAATGCAGGAAGGCTTTTAGGTGGAGGAAGTGGGCTCTGG
CTGTCTTGTGACTATCACTCGCTCATCACAGAAGCCACAGTACAGATAGGAACGGAGACACAGA
GACACAGCACAGCGAAGGGACTCTCGGCATAGAACTGTACCATGCCCAACTACAAACTGCTTTA
TTTTAATATGAGGGGAAGAGCAGAAATTATTCGTTATATATTTGCTTATTTGGACATCAAGTAC
GAAGATCACAGAATAGAACAAGCTGACTGGCCTAAAATCAAACCAACTCTTCCATTTGGCAAAA
TCCCTGTTTTGGAGGTGGAAGGACTTACACTTCACCAGAGCCTCGCAATAGCAAGATATTTGAC
CAAAAACACAGATTTGGCTGGGAAGACAGAGCTGGAGCAGTGTCAAGTGGATGCAGTGGTGGAT
ACCCTGGACGATTTCATGTCACTCTTTCCATGGGCAGAGGAAAATCAAGATCTAAAAGAGCGGA
CGTTCAATGACTTGCTCACACGTCAAGCACCTCATCTTCTGAAAGATTTGGACACATACTTAGG
AGACAAAGAGTGGTTTATTGGCAATTATGTAACTTGGGCAGATTTCTATTGGGATATCTGCAGC
ACCACACTTTTGGTCTTAAAGCCCGACCTGTTGGGCATCTACCCCAGACTGGTGTCACTACGGA
ACAAAGTCCAAGCTATTCCTGCTATTTCTGCCTGGATCCTAAAGAGGCCACAGACAAAACTCTA
AATGATTCTGGACCCATCATCAGATGAGAAGTCCATCAGCCGGCTACAGCATTTGCAAACTTCT
CGCCACCACTAGGCCTTCCTCTCACTTTGTAGTATTGTGCTTGCTGTGTAGGATTCCTTTGTTG
TGACTTTGTCTTTTTCTGTAGGCATTTAGTTTCCAATATTTTTTCAAAACTTCACACGTTTTAT
AATTACAGGGAAATAGTTCACAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006236602 ⟹ XP_006236664

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	95,698,265 - 95,727,721 (-)	NCBI
mRatBN7.2	4	94,368,426 - 94,397,914 (-)	NCBI
Rnor_6.0	4	95,945,356 - 95,970,634 (-)	NCBI
Rnor_5.0	4	160,734,255 - 160,758,902 (-)	NCBI

Sequence:

show sequence

AGAGGCCTGTGGTGTAAGACTAAGAAGAAAGAACATGTAGCAATCCGTACACACAAGCACCTGT
GACTGCGACTTTACTCTTTATGCAAATTTGGTGGGTATATACAGAGAGCTTGGGAAATGGTGGC
AAAAGCTACCAGAGCTCCTTCCAGGCTGAACTTTGGACGTGTGTATCTCGTGTGAGCAATGCAG
GAAGGCTTTTAGGTGGAGGAAGTGGGCTCTGGCTGTCTTGTGACTATCACTCGCTCATCACAGA
AGCCACAGTACAGATAGGAACGGAGACACAGAGACACAGCACAGCGAAGGGACTCTCGGCATAG
AACTGTACCATGCCCAACTACAAACTGCTTTATTTTAATATGAGGGGAAGAGCAGAAATTATTC
GTTATATATTTGCTTATTTGGACATCAAGTACGAAGATCACAGAATAGAACAAGCTGACTGGCC
TAAAATCAAACCAACTCTTCCATTTGGCAAAATCCCTGTTTTGGAGGTGGAAGGACTTACACTT
CACCAGAGCCTCGCAATAGCAAGATATTTGACCAAAAACACAGATTTGGCTGGGAAGACAGAGC
TGGAGCAGTGTCAAGTGGATGCAGTGGTGGATACCCTGGACGATTTCATGTCACTCTTTCCATG
GGCAGAGGAAAATCAAGATCTAAAAGAGCGGACGTTCAATGACTTGCTCACACGTCAAGCACCT
CATCTTCTGAAAGATTTGGACACATACTTAGGAGACAAAGAGTGGTTTATTGGCAATTATCAGG
TAACTTGGGCAGATTTCTATTGGGATATCTGCAGCACCACACTTTTGGTCTTAAAGCCCGACCT
GTTGGGCATCTACCCCAGACTGGTGTCACTACGGAACAAAGTCCAAGCTATTCCTGCTATTTCT
GCCTGGATCCTAAAGAGGCCACAGACAAAACTCTAAATGATTCTGGACCCATCATCAGATGAGA
AGTCCATCAGCCGGCTACAGCATTTGCAAACTTCTCGCCACCACTAGGCCTTCCTCTCACTTTG
TAGTATTGTGCTTGCTGTGTAGGATTCCTTTGTTGTGACTTTGTCTTTTTCTGTAGGCATTTAG
TTTCCAATATTTTTTCAAAACTTCACACGTTTTATAATTACAGGGAAATAGTTCACAATTTATG
TTGTTGTGCATTGATATCAGCTTGCATGGATGCCTCAGTTACACACTAGTTTCCTGGACAGTGT
TATTAGTCAGCACAGTATCTTAATTACGACTAATCATGTGAAATACAGATTTTAGAGCTAGCTA
TTCAATCAACAAATTGCTACCAGAAACTAATGGTCAATATAATGCCCACTAGTCACTACATGTT
CCTCAGGTATACACCAAAGTTACTTTACAAAAATGCACATCTGTCTGACATGTCACAAATTTGG
TAATAAGAAGGAACTCAAAGAGATTAAAGGGCAGCCAAGAAAAGTGATATTGAAGCTTAAATGA
AATTCCACAGAAAGGAGTAACAAAAAGTTGACTGAATTCAGCACTGTTGCAATTCAGGAGGCTG
TAGAGAAAGGACCTCCATCAGCTCACTGACAAGGAAAGGAGCTGTGATGTAGAAAGTTAGGAGC
CCCAGAGACAAGTGAGTGGGTTACAATAATCCTTCACATTAAAACAAAAACAAAAACCAAGCAA
AACAGGCTGGAGATAGTTCAGCAGTTAAGAGCACTCAAGTACATAAATATTAAAATAATAATAA
TAATGGGCTGTGATGTCTAATGGCACTGGCCCAATGAGGGACAACTGAGGATTCATTCTATGTA
ACAAATCCCTATTTACTGCCA

hide sequence

RefSeq Acc Id:

XM_006236603 ⟹ XP_006236665

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	95,698,265 - 95,727,733 (-)	NCBI
mRatBN7.2	4	94,368,426 - 94,397,931 (-)	NCBI
Rnor_6.0	4	95,945,356 - 95,970,656 (-)	NCBI
Rnor_5.0	4	160,734,255 - 160,758,902 (-)	NCBI

Sequence:

show sequence

ACAGGACTTGTTCTTATTCCCCAGAGGCCTGTGGTGTAAGACTAAGAAGAAAGAACATGTAGCA
ATCCGTACACACAAGCACCTGTGACTGCGACTTTACTCTTTATGCAAATTTGGTGGGTATATAC
AGAGAGCTTGGGAAATGGTGGCAAAAGCTACCAGAGCTCCTTCCAGGCTGAACTTTGGACGTGT
GTATCTCGTGTGAGCAATGCAGGAAGGCTTTTAGGTGGAGGAAGTGGGCTCTGGCTGTCTTGTG
ACTATCACTCGCTCATCACAGAAGCCACAGTACAGATAGGAACGGAGACACAGAGACACAGCAC
AGCGAAGGGACTCTCGGCATAGAACTGTACCATGCCCAACTACAAACTGCTTTATTTTAATATG
AGGGGAAGAGCAGAAATTATTCGTTATATATTTGCTTATTTGGACATCAAGTACGAAGATCACA
GAATAGAACAAGCTGACTGGCCTAAAATCAAACCAAATTTGGCTGGGAAGACAGAGCTGGAGCA
GTGTCAAGTGGATGCAGTGGTGGATACCCTGGACGATTTCATGTCACTCTTTCCATGGGCAGAG
GAAAATCAAGATCTAAAAGAGCGGACGTTCAATGACTTGCTCACACGTCAAGCACCTCATCTTC
TGAAAGATTTGGACACATACTTAGGAGACAAAGAGTGGTTTATTGGCAATTATCAGGTAACTTG
GGCAGATTTCTATTGGGATATCTGCAGCACCACACTTTTGGTCTTAAAGCCCGACCTGTTGGGC
ATCTACCCCAGACTGGTGTCACTACGGAACAAAGTCCAAGCTATTCCTGCTATTTCTGCCTGGA
TCCTAAAGAGGCCACAGACAAAACTCTAAATGATTCTGGACCCATCATCAGATGAGAAGTCCAT
CAGCCGGCTACAGCATTTGCAAACTTCTCGCCACCACTAGGCCTTCCTCTCACTTTGTAGTATT
GTGCTTGCTGTGTAGGATTCCTTTGTTGTGACTTTGTCTTTTTCTGTAGGCATTTAGTTTCCAA
TATTTTTTCAAAACTTCACACGTTTTATAATTACAGGGAAATAGTTCACAATTTATGTTGTTGT
GCATTGATATCAGCTTGCATGGATGCCTCAGTTACACACTAGTTTCCTGGACAGTGTTATTAGT
CAGCACAGTATCTTAATTACGACTAATCATGTGAAATACAGATTTTAGAGCTAGCTATTCAATC
AACAAATTGCTACCAGAAACTAATGGTCAATATAATGCCCACTAGTCACTACATGTTCCTCAGG
TATACACCAAAGTTACTTTACAAAAATGCACATCTGTCTGACATGTCACAAATTTGGTAATAAG
AAGGAACTCAAAGAGATTAAAGGGCAGCCAAGAAAAGTGATATTGAAGCTTAAATGAAATTCCA
CAGAAAGGAGTAACAAAAAGTTGACTGAATTCAGCACTGTTGCAATTCAGGAGGCTGTAGAGAA
AGGACCTCCATCAGCTCACTGACAAGGAAAGGAGCTGTGATGTAGAAAGTTAGGAGCCCCAGAG
ACAAGTGAGTGGGTTACAATAATCCTTCACATTAAAACAAAAACAAAAACCAAGCAAAACAGGC
TGGAGATAGTTCAGCAGTTAAGAGCACTCAAGTACATAAATATTAAAATAATAATAATAATGGG
CTGTGATGTCTAATGGCACTGGCCCAATGAGGGACAACTGAGGATTCATTCTATGTAACAAATC
CCTATTTACTGCCA

hide sequence

RefSeq Acc Id:

XM_039108297 ⟹ XP_038964225

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	95,704,812 - 95,727,722 (-)	NCBI
mRatBN7.2	4	94,375,776 - 94,397,916 (-)	NCBI

RefSeq Acc Id:

XM_063286650 ⟹ XP_063142720

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	95,703,179 - 95,727,710 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_113832	(Get FASTA)	NCBI Sequence Viewer
	XP_006236664	(Get FASTA)	NCBI Sequence Viewer
	XP_006236665	(Get FASTA)	NCBI Sequence Viewer
	XP_038964225	(Get FASTA)	NCBI Sequence Viewer
	XP_063142720	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB72099	(Get FASTA)	NCBI Sequence Viewer
	AAH87590	(Get FASTA)	NCBI Sequence Viewer
	BAA22898	(Get FASTA)	NCBI Sequence Viewer
	EDL91600	(Get FASTA)	NCBI Sequence Viewer
	EDL91601	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000008826
	ENSRNOP00000008826.3
	ENSRNOP00000106939
GenBank Protein	O35543	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113832 ⟸ NM_031644

- UniProtKB:

O35351 (UniProtKB/Swiss-Prot), O35543 (UniProtKB/Swiss-Prot), A6KF23 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQS
LAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLL
KDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWIL
KRPQTKL

hide sequence

RefSeq Acc Id:	XP_006236665 ⟸ XM_006236603
- Peptide Label:	isoform X2
- Sequence:	show sequence MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPNLAGKTELEQCQVDAVVDTL DDFMSLFPWAEENQDLKERTFNDLLTRQAPHLLKDLDTYLGDKEWFIGNYQVTWADFYWDICST TLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWILKRPQTKL hide sequence

RefSeq Acc Id:

XP_006236664 ⟸ XM_006236602

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQS
LAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQAPHLL
KDLDTYLGDKEWFIGNYQVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKVQAIPAISAWI
LKRPQTKL

hide sequence

Ensembl Acc Id:

ENSRNOP00000008826 ⟸ ENSRNOT00000008826

RefSeq Acc Id:	XP_038964225 ⟸ XM_039108297
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063142720 ⟸ XM_063286650
- Peptide Label:	isoform X3

Protein Domains

GST C-terminal GST N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35543-F1-model_v2	AlphaFold	O35543	1-199	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693096

Promoter ID:

EPDNEW_R3621

Type:

multiple initiation site

Name:

Hpgds_1

Description:

hematopoietic prostaglandin D synthase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	95,970,372 - 95,970,432	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:69251	AgrOrtholog
BioCyc Gene	G2FUF-44603	BioCyc
BioCyc Pathway	PWY66-374 [C20 prostanoid biosynthesis]	BioCyc
BioCyc Pathway Image	PWY66-374	BioCyc
Ensembl Genes	ENSRNOG00000006583	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000008826	ENTREZGENE
	ENSRNOT00000008826.6	UniProtKB/Swiss-Prot
	ENSRNOT00000123843	ENTREZGENE
Gene3D-CATH	1.20.1050.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutaredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7307804	IMAGE-MGC_LOAD
InterPro	Glutathione-S-Trfase_C-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutathione-S-Trfase_C_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutathione_S-Trfase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutathione_S-Trfase_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_superfamily	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:58962	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:105397	IMAGE-MGC_LOAD
NCBI Gene	58962	ENTREZGENE
PANTHER	GLUTATHIONE S-TRANSFERASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	GST_C_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Hpgds	PhenoGen
PROSITE	GST_CTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GST_NTER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000006583	RatGTEx
Superfamily-SCOP	GST C-terminal domain-like	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	SSF52833	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6KF23	ENTREZGENE, UniProtKB/TrEMBL
	HPGDS_RAT	UniProtKB/Swiss-Prot
	O35351	ENTREZGENE
	O35543	ENTREZGENE
UniProt Secondary	O35351	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-01-14	Hpgds	hematopoietic prostaglandin D synthase	Ptgds2	prostaglandin D2 synthase 2, hematopoietic	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-18	Ptgds2	prostaglandin D2 synthase 2, hematopoietic	Ptgds2	prostaglandin D2 synthase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Ptgds2	prostaglandin D2 synthase 2			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

BioCyc Pathways