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Gene: Hpgds (hematopoietic prostaglandin D synthase) Rattus norvegicus
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Symbol: Hpgds
Name: hematopoietic prostaglandin D synthase
Description: Predicted to have several functions, including glutathione transferase activity; metal ion binding activity; and prostaglandin-D synthase activity. Predicted to be involved in glutathione metabolic process; negative regulation of male germ cell proliferation; and prostaglandin metabolic process. Predicted to localize to the cytoplasm. Orthologous to human HPGDS (hematopoietic prostaglandin D synthase); PARTICIPATES IN prostaglandin biosynthetic pathway; arachidonic acid metabolic pathway; eicosanoid metabolic pathway; INTERACTS WITH (+)-schisandrin B; (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glutathione S-transferase; glutathione-dependent PGD synthase; glutathione-dependent PGD synthetase; glutathione-requiring prostaglandin D synthase; GST class-sigma; H-PGDS; MGC105397; prostaglandin D2 synthase 2; prostaglandin D2 synthase 2 hematopoietic; prostaglandin D2 synthase 2, hematopoietic; prostaglandin-H2 D-isomerase; Ptgds2
Orthologs:
Homo sapiens (human) : HPGDS (hematopoietic prostaglandin D synthase)  HGNC  Alliance
Mus musculus (house mouse) : Hpgds (hematopoietic prostaglandin D synthase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HPGDS (hematopoietic prostaglandin D synthase)
Canis lupus familiaris (dog) : HPGDS (hematopoietic prostaglandin D synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hpgds (hematopoietic prostaglandin D synthase)
Sus scrofa (pig) : HPGDS (hematopoietic prostaglandin D synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0495,945,356 - 95,970,666 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04160,734,255 - 160,758,902 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4494,611,607 - 94,636,147 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1494,856,088 - 94,880,628 (-)NCBI
Celera489,106,678 - 89,131,218 (-)NCBICelera
Cytogenetic Map4q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hpgds
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69251
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.